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The map label for this gene is arsC [H]

Identifier: 197104901

GI number: 197104901

Start: 1629090

End: 1629500

Strand: Reverse

Name: arsC [H]

Synonym: PHZ_c1436

Alternate gene names: 197104901

Gene position: 1629500-1629090 (Counterclockwise)

Preceding gene: 197104902

Following gene: 197104893

Centisome position: 40.78

GC content: 68.86

Gene sequence:

>411_bases
ATGTCCGAATTCCCGATCACCATCTTCCACAACCCGGCTTGCGGCACCTCCCGCAACACCGTCGCCATGGTGCGGGCCGC
CGGCTACGAGCCCGAGGTCGTCGAGTACCTGCAGGCCGGCTGGACCAAGCCGCAGCTCCAGGAACTGCTCGCCGCCATGG
GCGCCACGCCGCGCGACATCCTCCGCGGCAAGGGGACGCCGGCGGCCGAGCTGGGCCTGCTCGAACCCCATGTCGGCGAC
GACGCCATCCTCGACGCGATGGTGGCGCACCCGATCCTCGTGAACCGCCCCATCGTCGTCACGCCCAAGGGCGTCAAACT
CAGCCGGCCTTCGGAAGCCGTCCTGGACTTGCTCGACCGCAAGCCCGACAGCTTCACCAAGGAAGATGGCGAGGTCGTGC
GGCTCGCCTGA

Upstream 100 bases:

>100_bases
TCGTCGCCATCGTGAACCGGTCCAAGCGCTGGTACGAGCGGGGCGCGGCCGTTCAACGGGTGGCGGCGCGCTGCGCCCCG
CCGATCACGAGGTGAGCTGC

Downstream 100 bases:

>100_bases
CCGGCGCTTGCTACGGTCAGCCGTGCTGGGCGAACACCCGCGTCTTGCCGCCCGGAAGCAGCAGGAGCGTGGCGTAGGCT
TCCCTCCGACCGTCCGGCAT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSEFPITIFHNPACGTSRNTVAMVRAAGYEPEVVEYLQAGWTKPQLQELLAAMGATPRDILRGKGTPAAELGLLEPHVGD
DAILDAMVAHPILVNRPIVVTPKGVKLSRPSEAVLDLLDRKPDSFTKEDGEVVRLA

Sequences:

>Translated_136_residues
MSEFPITIFHNPACGTSRNTVAMVRAAGYEPEVVEYLQAGWTKPQLQELLAAMGATPRDILRGKGTPAAELGLLEPHVGD
DAILDAMVAHPILVNRPIVVTPKGVKLSRPSEAVLDLLDRKPDSFTKEDGEVVRLA
>Mature_135_residues
SEFPITIFHNPACGTSRNTVAMVRAAGYEPEVVEYLQAGWTKPQLQELLAAMGATPRDILRGKGTPAAELGLLEPHVGDD
AILDAMVAHPILVNRPIVVTPKGVKLSRPSEAVLDLLDRKPDSFTKEDGEVVRLA

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=129, Percent_Identity=53.4883720930233, Blast_Score=141, Evalue=2e-35,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=36.8421052631579, Blast_Score=83, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 14680; Mature: 14549

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFPITIFHNPACGTSRNTVAMVRAAGYEPEVVEYLQAGWTKPQLQELLAAMGATPRDI
CCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHH
LRGKGTPAAELGLLEPHVGDDAILDAMVAHPILVNRPIVVTPKGVKLSRPSEAVLDLLDR
HCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCHHCCCCEEECCCCCEECCCHHHHHHHHHC
KPDSFTKEDGEVVRLA
CCCCCCCCCCCEEEEC
>Mature Secondary Structure 
SEFPITIFHNPACGTSRNTVAMVRAAGYEPEVVEYLQAGWTKPQLQELLAAMGATPRDI
CCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHH
LRGKGTPAAELGLLEPHVGDDAILDAMVAHPILVNRPIVVTPKGVKLSRPSEAVLDLLDR
HCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCHHCCCCEEECCCCCEECCCHHHHHHHHHC
KPDSFTKEDGEVVRLA
CCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]