Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 197104781

GI number: 197104781

Start: 1491440

End: 1493764

Strand: Reverse

Name: rnr [H]

Synonym: PHZ_c1315

Alternate gene names: 197104781

Gene position: 1493764-1491440 (Counterclockwise)

Preceding gene: 197104782

Following gene: 197104780

Centisome position: 37.38

GC content: 72.47

Gene sequence:

>2325_bases
ATGGCCCGACCGCACAAGCCGAAATCCGCCCGAACGCCCCAGAAGGCGGCCCTGAAAGCCCCTCAGGGCCTGCCGGACCG
CGAGACGCTGCTGAGGTTCATCCGCGAGAGCGGCGAGACCGACAAGGCCGCCATCGCCCGCGCCTTCGGCCTCAAGGGCG
CCGACCGTCGCGCGTTGCGGATGATGCTGAACGATATGCAGGACGACGGGACGTTGGCCCGCCGCAGCCGGCGCGGCTTC
GCCGAGACGGGCGCCCTGCCCGAGGTCGGCGTGGTGGACGTGGTCGAGCGCGATCCGGACGGCGACCTGCTGGTCAAGCT
GACCAAGGGCGAGGACGCCCCGCTCACGCCGCTGGCGCCCGGCGGCGACGTGGCCGGCCCGGCGCCCGGCCTGGGCGACC
GGCTGCTGGTGCGGTTCGTGCGCCTGGAGAACGGCGAGTTCGAGGCCCGGCTGATCAAGCGCCTGGGCCAGAGCGCGCAT
CGCATCCTGGGGGTCGTGCGCAAGGTGCGGCGGGAAGTGCGGCTCGAGCCGGTCGACCGCCGCTCCAAGGACAGCCTGGT
GCTCCCCGACGCCGGCGAGCTTCGGGACGGCGACCTGGTCGTCGCCCAGGTGGAAGGCTCCATCGGCCGCTACGGCCCCA
AGCGCGGCAAGGTGCTGGAGGTGGTGGGGCGCGAGGACGAGCCGCGCGCCGCCTCGCTGATCGCGATCCACGCCCACGGC
ATCCCGACCGGCTTCTCCCAGGCCGCCGAAGCCGAGGCCGAGGCCGCCGAGCCGCCGACGCTGGAGGGCCGTGAGGACCT
GCGCGAGGTCCCGCTGATCACCATCGACCCGGCCGACGCCCGCGACCACGACGACGCGGTCTACGCCCATGCGGACGACG
ATCCGAAGAACCCCGGCGGGTGGGTGGTCTGGGTCGCCATCGCCGACGTGGCCGCCTACGTCCGGCCGGGCTCGGCGCTG
GACAAGGAGGCCCGCGAGAAGGGCAATAGCGTCTACTTCCCCGACCGGGTCGAACCGATGCTGCCCGAGCGGCTGTCCAA
CGGCCTGTGCTCCTTGCGCGAAGGCGAGAACCGCGCCTGCCTCGCCGTGCGGATGGTGTTCGGCGCCGACGGCCGCAAGC
GCTCGCACCGCTTCGTGCGCGGCCTGATGCGCTCGGCCGCCAAGCTCGCCTACGAACAGGCCCAGGCGGCGATCGACGGC
AAGCTCGACGACAAGACCGGGCCGCTGCTGGAGCCGGTGATCAGGCCGCTGTGGGCGGCCTACGCCTGCCTGAAAAAGGG
CCGCGACGCCCGCTCGCCGCTGGCCATCGAGAGCCTGGAGCGCAAGATCCACATCGACGAGATGGGCCGGGTCTCCTCGA
TCCTGCCGCGCGAGGCGCTCGAGGCGCATCGGCTGATCGAGGAGTTCATGATCCAGGCGAACGTCTGCGCCGCCGAGACC
CTGGAGCAGAAGAAGACGCCGCTGATCTACCGGGTGCACGATGCGCCCAGCCAGGAGAAGATCTTCAACCTCGTCGACTT
CCTGGCGACGCTGGGCCTGCCCTGGACCAAGGGCGAGGCGCCGCGCACCGAGCGCTTCAACCGCCTGCTGGACGAGACGC
GGGACACCCCGCACGCGGAGATCGTCAACGAGGTTGTCCTGCGCACCCAGATGCAGGCGCACTACAGCACCGAGAACATC
GGCCATTACGGCCTGAACCTGGCCAAGTACGCCCACTTCACCTCGCCGATCCGCCGCTACGCCGACCTGATCGTGCACCG
GGCGCTGATCGCCTCCCTCGGTCTCGGCAAGGACGGCCTTTCCGAGCGCGACATCGCTCAGATGAAGGGCACGGCCGAGC
AGATCACCTTCGCCGAACGCCGGGCGATGGCCGCCGAGCGCGACGCGACCGACCGCTACATCGCCGCCTTCCTCTCGGAC
CGCATCGGCGCGGAGTTCGCGGGCAAGATCACCGGCGTCACCCGCTTCGGCCTGTTCGTGCGGTTGGCCGAGACCGGCGC
CGACGGCCTCGTGCCGGTCTCCAGCCTGGGCGGGGAGTACTTCGTCCACGACGACCGGGCCCATGCGCTGGTGGGGGAGC
GGACCGGCGCGCGCTGGCCGCTGGGCATGAGCGTGCAGGTGCGCCTGCGCGAGGCCACGCCCATCACGGGCGGACTGCTG
TTCGAGATGCTGAGCGAACCGGCCCCGCCCGACCGCTCGGCGCCGCGGCCCAGGCTGGGCGTGCGGGCGCGCGGCGACCG
GCGGCCCGGCGGCGGCAAGCCTCGCGGCGGCGGCGCGGGCCGCGCGCCGAAGGCCAAGGGTCGGACGACACGCCGCGGGC
GTTGA

Upstream 100 bases:

>100_bases
CTCGCCATGGCTGCCGGGATCCTGGCGGCGGCGGCGCTCGCCTTCCTCTGACCGCTCGCGGGAGCCGCGTCGGGGCGGCG
ACGTTGTGCTAAGCAGCGCC

Downstream 100 bases:

>100_bases
CGCGGCGACAGCCTTCCGCGCCCGCGCCGGGCCTCATACATTTGTTCGATGTCCGACGCCCCGCTCCTGCCCCTGAAGCC
CGAAGGTCCGGCCCGTACGC

Product: exoribonuclease, VacB and RNase II family

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MARPHKPKSARTPQKAALKAPQGLPDRETLLRFIRESGETDKAAIARAFGLKGADRRALRMMLNDMQDDGTLARRSRRGF
AETGALPEVGVVDVVERDPDGDLLVKLTKGEDAPLTPLAPGGDVAGPAPGLGDRLLVRFVRLENGEFEARLIKRLGQSAH
RILGVVRKVRREVRLEPVDRRSKDSLVLPDAGELRDGDLVVAQVEGSIGRYGPKRGKVLEVVGREDEPRAASLIAIHAHG
IPTGFSQAAEAEAEAAEPPTLEGREDLREVPLITIDPADARDHDDAVYAHADDDPKNPGGWVVWVAIADVAAYVRPGSAL
DKEAREKGNSVYFPDRVEPMLPERLSNGLCSLREGENRACLAVRMVFGADGRKRSHRFVRGLMRSAAKLAYEQAQAAIDG
KLDDKTGPLLEPVIRPLWAAYACLKKGRDARSPLAIESLERKIHIDEMGRVSSILPREALEAHRLIEEFMIQANVCAAET
LEQKKTPLIYRVHDAPSQEKIFNLVDFLATLGLPWTKGEAPRTERFNRLLDETRDTPHAEIVNEVVLRTQMQAHYSTENI
GHYGLNLAKYAHFTSPIRRYADLIVHRALIASLGLGKDGLSERDIAQMKGTAEQITFAERRAMAAERDATDRYIAAFLSD
RIGAEFAGKITGVTRFGLFVRLAETGADGLVPVSSLGGEYFVHDDRAHALVGERTGARWPLGMSVQVRLREATPITGGLL
FEMLSEPAPPDRSAPRPRLGVRARGDRRPGGGKPRGGGAGRAPKAKGRTTRRGR

Sequences:

>Translated_774_residues
MARPHKPKSARTPQKAALKAPQGLPDRETLLRFIRESGETDKAAIARAFGLKGADRRALRMMLNDMQDDGTLARRSRRGF
AETGALPEVGVVDVVERDPDGDLLVKLTKGEDAPLTPLAPGGDVAGPAPGLGDRLLVRFVRLENGEFEARLIKRLGQSAH
RILGVVRKVRREVRLEPVDRRSKDSLVLPDAGELRDGDLVVAQVEGSIGRYGPKRGKVLEVVGREDEPRAASLIAIHAHG
IPTGFSQAAEAEAEAAEPPTLEGREDLREVPLITIDPADARDHDDAVYAHADDDPKNPGGWVVWVAIADVAAYVRPGSAL
DKEAREKGNSVYFPDRVEPMLPERLSNGLCSLREGENRACLAVRMVFGADGRKRSHRFVRGLMRSAAKLAYEQAQAAIDG
KLDDKTGPLLEPVIRPLWAAYACLKKGRDARSPLAIESLERKIHIDEMGRVSSILPREALEAHRLIEEFMIQANVCAAET
LEQKKTPLIYRVHDAPSQEKIFNLVDFLATLGLPWTKGEAPRTERFNRLLDETRDTPHAEIVNEVVLRTQMQAHYSTENI
GHYGLNLAKYAHFTSPIRRYADLIVHRALIASLGLGKDGLSERDIAQMKGTAEQITFAERRAMAAERDATDRYIAAFLSD
RIGAEFAGKITGVTRFGLFVRLAETGADGLVPVSSLGGEYFVHDDRAHALVGERTGARWPLGMSVQVRLREATPITGGLL
FEMLSEPAPPDRSAPRPRLGVRARGDRRPGGGKPRGGGAGRAPKAKGRTTRRGR
>Mature_773_residues
ARPHKPKSARTPQKAALKAPQGLPDRETLLRFIRESGETDKAAIARAFGLKGADRRALRMMLNDMQDDGTLARRSRRGFA
ETGALPEVGVVDVVERDPDGDLLVKLTKGEDAPLTPLAPGGDVAGPAPGLGDRLLVRFVRLENGEFEARLIKRLGQSAHR
ILGVVRKVRREVRLEPVDRRSKDSLVLPDAGELRDGDLVVAQVEGSIGRYGPKRGKVLEVVGREDEPRAASLIAIHAHGI
PTGFSQAAEAEAEAAEPPTLEGREDLREVPLITIDPADARDHDDAVYAHADDDPKNPGGWVVWVAIADVAAYVRPGSALD
KEAREKGNSVYFPDRVEPMLPERLSNGLCSLREGENRACLAVRMVFGADGRKRSHRFVRGLMRSAAKLAYEQAQAAIDGK
LDDKTGPLLEPVIRPLWAAYACLKKGRDARSPLAIESLERKIHIDEMGRVSSILPREALEAHRLIEEFMIQANVCAAETL
EQKKTPLIYRVHDAPSQEKIFNLVDFLATLGLPWTKGEAPRTERFNRLLDETRDTPHAEIVNEVVLRTQMQAHYSTENIG
HYGLNLAKYAHFTSPIRRYADLIVHRALIASLGLGKDGLSERDIAQMKGTAEQITFAERRAMAAERDATDRYIAAFLSDR
IGAEFAGKITGVTRFGLFVRLAETGADGLVPVSSLGGEYFVHDDRAHALVGERTGARWPLGMSVQVRLREATPITGGLLF
EMLSEPAPPDRSAPRPRLGVRARGDRRPGGGKPRGGGAGRAPKAKGRTTRRGR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=511, Percent_Identity=27.3972602739726, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI190014625, Length=531, Percent_Identity=26.9303201506591, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI190014623, Length=431, Percent_Identity=29.4663573085847, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI19115966, Length=495, Percent_Identity=29.8989898989899, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI219521928, Length=495, Percent_Identity=29.8989898989899, Blast_Score=152, Evalue=1e-36,
Organism=Escherichia coli, GI87082383, Length=738, Percent_Identity=35.5013550135501, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1787542, Length=443, Percent_Identity=34.3115124153499, Blast_Score=175, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=441, Percent_Identity=29.9319727891156, Blast_Score=162, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17553506, Length=445, Percent_Identity=29.6629213483146, Blast_Score=159, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=480, Percent_Identity=31.0416666666667, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24649634, Length=434, Percent_Identity=29.2626728110599, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI19922976, Length=436, Percent_Identity=26.605504587156, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24654597, Length=436, Percent_Identity=26.605504587156, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24654592, Length=436, Percent_Identity=26.605504587156, Blast_Score=126, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84781; Mature: 84650

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPHKPKSARTPQKAALKAPQGLPDRETLLRFIRESGETDKAAIARAFGLKGADRRALR
CCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHH
MMLNDMQDDGTLARRSRRGFAETGALPEVGVVDVVERDPDGDLLVKLTKGEDAPLTPLAP
HHHHHCCCCHHHHHHHHCCCHHHCCCCCCCCEEHEECCCCCCEEEEEECCCCCCCCCCCC
GGDVAGPAPGLGDRLLVRFVRLENGEFEARLIKRLGQSAHRILGVVRKVRREVRLEPVDR
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RSKDSLVLPDAGELRDGDLVVAQVEGSIGRYGPKRGKVLEVVGREDEPRAASLIAIHAHG
CCCCCEECCCCCCCCCCCEEEEEECCCHHCCCCCCCCEEEEECCCCCCCCEEEEEEEECC
IPTGFSQAAEAEAEAAEPPTLEGREDLREVPLITIDPADARDHDDAVYAHADDDPKNPGG
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCCCC
WVVWVAIADVAAYVRPGSALDKEAREKGNSVYFPDRVEPMLPERLSNGLCSLREGENRAC
EEEEHHHHHHHHHHCCCHHCCHHHHHCCCEEECCCCCCCCCHHHHHCCCEECCCCCCCEE
LAVRMVFGADGRKRSHRFVRGLMRSAAKLAYEQAQAAIDGKLDDKTGPLLEPVIRPLWAA
EEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
YACLKKGRDARSPLAIESLERKIHIDEMGRVSSILPREALEAHRLIEEFMIQANVCAAET
HHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LEQKKTPLIYRVHDAPSQEKIFNLVDFLATLGLPWTKGEAPRTERFNRLLDETRDTPHAE
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
IVNEVVLRTQMQAHYSTENIGHYGLNLAKYAHFTSPIRRYADLIVHRALIASLGLGKDGL
HHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SERDIAQMKGTAEQITFAERRAMAAERDATDRYIAAFLSDRIGAEFAGKITGVTRFGLFV
CHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
RLAETGADGLVPVSSLGGEYFVHDDRAHALVGERTGARWPLGMSVQVRLREATPITGGLL
HHHCCCCCCCCCHHHCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHH
FEMLSEPAPPDRSAPRPRLGVRARGDRRPGGGKPRGGGAGRAPKAKGRTTRRGR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARPHKPKSARTPQKAALKAPQGLPDRETLLRFIRESGETDKAAIARAFGLKGADRRALR
CCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHH
MMLNDMQDDGTLARRSRRGFAETGALPEVGVVDVVERDPDGDLLVKLTKGEDAPLTPLAP
HHHHHCCCCHHHHHHHHCCCHHHCCCCCCCCEEHEECCCCCCEEEEEECCCCCCCCCCCC
GGDVAGPAPGLGDRLLVRFVRLENGEFEARLIKRLGQSAHRILGVVRKVRREVRLEPVDR
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RSKDSLVLPDAGELRDGDLVVAQVEGSIGRYGPKRGKVLEVVGREDEPRAASLIAIHAHG
CCCCCEECCCCCCCCCCCEEEEEECCCHHCCCCCCCCEEEEECCCCCCCCEEEEEEEECC
IPTGFSQAAEAEAEAAEPPTLEGREDLREVPLITIDPADARDHDDAVYAHADDDPKNPGG
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCCCCCC
WVVWVAIADVAAYVRPGSALDKEAREKGNSVYFPDRVEPMLPERLSNGLCSLREGENRAC
EEEEHHHHHHHHHHCCCHHCCHHHHHCCCEEECCCCCCCCCHHHHHCCCEECCCCCCCEE
LAVRMVFGADGRKRSHRFVRGLMRSAAKLAYEQAQAAIDGKLDDKTGPLLEPVIRPLWAA
EEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
YACLKKGRDARSPLAIESLERKIHIDEMGRVSSILPREALEAHRLIEEFMIQANVCAAET
HHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LEQKKTPLIYRVHDAPSQEKIFNLVDFLATLGLPWTKGEAPRTERFNRLLDETRDTPHAE
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
IVNEVVLRTQMQAHYSTENIGHYGLNLAKYAHFTSPIRRYADLIVHRALIASLGLGKDGL
HHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SERDIAQMKGTAEQITFAERRAMAAERDATDRYIAAFLSDRIGAEFAGKITGVTRFGLFV
CHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
RLAETGADGLVPVSSLGGEYFVHDDRAHALVGERTGARWPLGMSVQVRLREATPITGGLL
HHHCCCCCCCCCHHHCCCCEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHH
FEMLSEPAPPDRSAPRPRLGVRARGDRRPGGGKPRGGGAGRAPKAKGRTTRRGR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]