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The map label for this gene is panC [H]

Identifier: 197104759

GI number: 197104759

Start: 1472939

End: 1473787

Strand: Reverse

Name: panC [H]

Synonym: PHZ_c1293

Alternate gene names: 197104759

Gene position: 1473787-1472939 (Counterclockwise)

Preceding gene: 197104762

Following gene: 197104758

Centisome position: 36.88

GC content: 74.68

Gene sequence:

>849_bases
ATGCCGCTGCCGATCGTCCGCACCGTCGCCGAGCTCCGCGCCCGGGTCGCCGCCTGGAAGGCCGGCGGAGAGCGGGTAGG
CTTCGTCCCCACCATGGGCGCGCTGCACGAGGGCCACCTGTCGCTGGTGCGCCTGGCCCGGACCAGGGCGCAGCGGGTGG
TGGCGAGCGTATTCGTCAATCCGACCCAGTTCGCCCCGAACGAGGACTTCGACGCCTACCCCCGGGACGAGGCGCGCGAC
GCCGCCCTCCTGGCGAGCGCCGGCTGCGACCTGCTGTTCGCCCCGACCCTGGCCGAGATGTACCCCGAGGGCTTCGCGAC
CACCGTCACCGTGGCCGGCGTCTCAGAGCCGCTGGACGGTCAGGCGCGGCCGGGCCACTTCACGGGCGTCGCCACCGTGG
TGACCAAGCTGCTCAACCAGGTCCAGGCCGACGTCGCGGTCTTCGGCGAGAAGGACTACCAGCAGCTCCAGGTGATCCGG
CGCCTGGTCCGCGACCTCGACATGCCCGTGGAGATCGTGGGCGGCCCGACCGCGCGGGCCGACGACGGCCTCGCCCTCTC
CTCGCGCAACGCCTACCTCGCCGCCGAGGAGCGGCCGGTGGCGGCGCGGCTGAACCAGGTGATGCGCGAGGCGATCGCCG
CCCTGAACGCCGGCGAGGCCGTAGCGGCGGTCGAGGCGCGCGCGGCCGAGGCGCTCGCGGCGGCCGGCTTCGGGCGGATC
GACTATGTGGAGGTGCGCGACGCCGGCGACCTCTCGCGCCTCGGACCCGGCCCGGTGGACCGTCCCGCCCGCCTCCTGGC
GGCCGCCGTCCTCGGACGGACCCGGCTGATCGACAACATGGCCGTCTAG

Upstream 100 bases:

>100_bases
ACCTATGCTACGTGAGCCCGCGCCGCCGAGCGCCGTCAACGCGCGGATCATCGCGGGCTGTGGATGGACTTGGGCCCCGC
CCCTCGCCATAAGCCCGGCC

Downstream 100 bases:

>100_bases
AGGCCTCCCGCGGCCCCTCGCCGCACGACAATCGGCGCCGGAGGGCTGCGGCCCGCCGCACCTCTAGGCTCCCGCGCGCC
GGCGAAGGGCTCGCCGGGAG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MPLPIVRTVAELRARVAAWKAGGERVGFVPTMGALHEGHLSLVRLARTRAQRVVASVFVNPTQFAPNEDFDAYPRDEARD
AALLASAGCDLLFAPTLAEMYPEGFATTVTVAGVSEPLDGQARPGHFTGVATVVTKLLNQVQADVAVFGEKDYQQLQVIR
RLVRDLDMPVEIVGGPTARADDGLALSSRNAYLAAEERPVAARLNQVMREAIAALNAGEAVAAVEARAAEALAAAGFGRI
DYVEVRDAGDLSRLGPGPVDRPARLLAAAVLGRTRLIDNMAV

Sequences:

>Translated_282_residues
MPLPIVRTVAELRARVAAWKAGGERVGFVPTMGALHEGHLSLVRLARTRAQRVVASVFVNPTQFAPNEDFDAYPRDEARD
AALLASAGCDLLFAPTLAEMYPEGFATTVTVAGVSEPLDGQARPGHFTGVATVVTKLLNQVQADVAVFGEKDYQQLQVIR
RLVRDLDMPVEIVGGPTARADDGLALSSRNAYLAAEERPVAARLNQVMREAIAALNAGEAVAAVEARAAEALAAAGFGRI
DYVEVRDAGDLSRLGPGPVDRPARLLAAAVLGRTRLIDNMAV
>Mature_281_residues
PLPIVRTVAELRARVAAWKAGGERVGFVPTMGALHEGHLSLVRLARTRAQRVVASVFVNPTQFAPNEDFDAYPRDEARDA
ALLASAGCDLLFAPTLAEMYPEGFATTVTVAGVSEPLDGQARPGHFTGVATVVTKLLNQVQADVAVFGEKDYQQLQVIRR
LVRDLDMPVEIVGGPTARADDGLALSSRNAYLAAEERPVAARLNQVMREAIAALNAGEAVAAVEARAAEALAAAGFGRID
YVEVRDAGDLSRLGPGPVDRPARLLAAAVLGRTRLIDNMAV

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=281, Percent_Identity=46.9750889679715, Blast_Score=233, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322046, Length=314, Percent_Identity=37.5796178343949, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 29914; Mature: 29782

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPIVRTVAELRARVAAWKAGGERVGFVPTMGALHEGHLSLVRLARTRAQRVVASVFVN
CCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTQFAPNEDFDAYPRDEARDAALLASAGCDLLFAPTLAEMYPEGFATTVTVAGVSEPLDG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHCCCCCEEEEEEECCCCCCCC
QARPGHFTGVATVVTKLLNQVQADVAVFGEKDYQQLQVIRRLVRDLDMPVEIVGGPTARA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCC
DDGLALSSRNAYLAAEERPVAARLNQVMREAIAALNAGEAVAAVEARAAEALAAAGFGRI
CCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
DYVEVRDAGDLSRLGPGPVDRPARLLAAAVLGRTRLIDNMAV
EEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLPIVRTVAELRARVAAWKAGGERVGFVPTMGALHEGHLSLVRLARTRAQRVVASVFVN
CCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTQFAPNEDFDAYPRDEARDAALLASAGCDLLFAPTLAEMYPEGFATTVTVAGVSEPLDG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCHHHHHCCCCCEEEEEEECCCCCCCC
QARPGHFTGVATVVTKLLNQVQADVAVFGEKDYQQLQVIRRLVRDLDMPVEIVGGPTARA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCC
DDGLALSSRNAYLAAEERPVAARLNQVMREAIAALNAGEAVAAVEARAAEALAAAGFGRI
CCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
DYVEVRDAGDLSRLGPGPVDRPARLLAAAVLGRTRLIDNMAV
EEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]