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The map label for this gene is luxQ [H]

Identifier: 197104642

GI number: 197104642

Start: 1349554

End: 1351323

Strand: Reverse

Name: luxQ [H]

Synonym: PHZ_c1176

Alternate gene names: 197104642

Gene position: 1351323-1349554 (Counterclockwise)

Preceding gene: 197104645

Following gene: 197104641

Centisome position: 33.81

GC content: 76.67

Gene sequence:

>1770_bases
GTGGCCGACATCTCCCAGCCCGCAGACGCCGGCGGCGTCACCGTCAACGAACAGGCCCTGAAGGCCCAGGCGGCCCTGCT
GCCCTACGCCCTCGCCGCGTTCGCGGTCAGCCTGCCGGTGTTCGTCTGGGCGGGCAGCCATGCGGTGAACGGCGCCTGGA
TGAGCGCCAGCTTCGCCCTGTTCGCCATCGGCTGGGGCGGCTTCTACGCCATCGTTAACTGGTTGAAGACCCCCGCGGCC
CGCGACCTGAAGACGCGCGGGCGGGTGCATGTGCTGGGCGGCCTGCTCTGGGCGGCGACGATCGCCCAGCTCGCGGCGTT
CGCCGACGGCGCGGGCCCGGCGCGCGAGACCCTGTTGCTGCTGTCGCTGGGGGCGGCCCTGATCTGCGTCTTCTTCGCCG
CCCCCTGGCTGCCCAGCCTGCTGATCGTGGCCCCGGCCGCCGTGGCGGGCCCCCTAGTCGCCCTCTTCAGCCGCGCCGCC
GACCAGCCGCTGGCCAAGCTGGGCCTGGCCGCCACCGCCCTGGCGCTGGCCCTGGCGCTCTTGGTGAACCGGATCCTGCG
CGGACAGTTCGCCCTCGCCGGCGAGCGCGAGCAGCTGATCGCCGAACGCGCCGAACAGGCCGAGGCCGCGCGGCGGCTGG
CCCGCTCGAAGTCGGACCTCGTCTCCACGCTGTCCGACGAAATCCGCAACGGTCTGACCGGCGTCGCCCACCTGCTGGCC
TCGGCGGCGGGCCAGGGCGGGCGGGCGGCTCCCTCGCGCCAGCAGGTCGCCGCCGCCCTCGACGCCGTGAACGACCTCCT
GGGCGTGCTCGACACCACCGTCGACGCCGAGACGGCCGAGGCCGGCGAGATCCACGTGGCGCCCCGCCCCGTCGACCTCG
TCGCGGTCGCCCGCGACCTCCTCCTGGCGCATCGCGCCGCCGCGGCGGCGAAGGGCCTGGAGATCGCCCTGCACGTGGAC
GCCGAGCTCGCCGGCGATTCCGGCGCCGCGATCGCCGATCCGCTGCGCGCGCGCCAGGCCCTCTCGGCCCTGATCGCCAA
CGCCGTGAAATTCACCCTCCGCGGCCGCGTCGAGGTCCGGCTGTCGCGCGCCGGCGAGCGCCGCATCGCCGTGGCGATCG
CGGACACCGGGCCCGGCCTGAGCGACGAGGAGCTCGCCACCGCCCTGCAGCCTTTCCAGCGCGTGGCGCGCACCAGCGCC
GGCGCCCCGGGCGCCGGTCTCGGCCTGCCGCTCGCCTGCCAGCTGGCGCGCCTGATGGGCGGCGAGATCCGCGCGCAGAG
CGCGGTCGGCGTCGGCAGCTGCTTCACGCTGGAGCTACCCTACGATCCCGACGTCGCCGCCTCAGCGGACGCTCCGCAGG
CCGCCGAGCCCGAGACGCGCCGGCTGCGCGTGCTGCTGGTCGAGGACGACGCGCTCGGCCGCGCCACCCTGCGCGCGACG
CTGGAGCAGCTCGGCCACCAGGTGGTCCAGGCGGCGGACCGCGCCCGCGCCGTCGAGCTGGCGCGGGTCTGCGACCTCGA
CCTGGCCGTCGTCGGCGCCGGCTCGGGCGGCCACGAGACCATCGCGGCCCTGCGCAGCCTGGCGGGGGACGCGGCCCGCA
CGCCCGTGGTCGCGGCGATCGGCGGCGATCCAGACGAGGCGCGCGCCTGCCAGGCCGCCGGCGCCGACGCCCTGCTGCGC
AAGCCCGTGGCCGTCCCGGCCGCCGCAAGAGCCATCGCCCAGGCGCTCTCGCCCCGCCCCTCGCCCGCCAATGACCGCGC
GGTAGCCTGA

Upstream 100 bases:

>100_bases
AGACCTTGCCGGCCGAATCTGTGGATTAAGGATCTCGCGTAACCGCCCGCCAACCCGGGGCCCCTACCCTCGCGGACCAG
CTTCGCGAAGGAGGCCCGCC

Downstream 100 bases:

>100_bases
CAAGGCCTCCAACACGCGTTTAAATGCCTCCAAACAGAGGGAGGCGCGCGTGCTGCTGCAGGGCCTGAAGGTCGTCGACT
TCACCGCCTATATCGCCGGG

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MADISQPADAGGVTVNEQALKAQAALLPYALAAFAVSLPVFVWAGSHAVNGAWMSASFALFAIGWGGFYAIVNWLKTPAA
RDLKTRGRVHVLGGLLWAATIAQLAAFADGAGPARETLLLLSLGAALICVFFAAPWLPSLLIVAPAAVAGPLVALFSRAA
DQPLAKLGLAATALALALALLVNRILRGQFALAGEREQLIAERAEQAEAARRLARSKSDLVSTLSDEIRNGLTGVAHLLA
SAAGQGGRAAPSRQQVAAALDAVNDLLGVLDTTVDAETAEAGEIHVAPRPVDLVAVARDLLLAHRAAAAAKGLEIALHVD
AELAGDSGAAIADPLRARQALSALIANAVKFTLRGRVEVRLSRAGERRIAVAIADTGPGLSDEELATALQPFQRVARTSA
GAPGAGLGLPLACQLARLMGGEIRAQSAVGVGSCFTLELPYDPDVAASADAPQAAEPETRRLRVLLVEDDALGRATLRAT
LEQLGHQVVQAADRARAVELARVCDLDLAVVGAGSGGHETIAALRSLAGDAARTPVVAAIGGDPDEARACQAAGADALLR
KPVAVPAAARAIAQALSPRPSPANDRAVA

Sequences:

>Translated_589_residues
MADISQPADAGGVTVNEQALKAQAALLPYALAAFAVSLPVFVWAGSHAVNGAWMSASFALFAIGWGGFYAIVNWLKTPAA
RDLKTRGRVHVLGGLLWAATIAQLAAFADGAGPARETLLLLSLGAALICVFFAAPWLPSLLIVAPAAVAGPLVALFSRAA
DQPLAKLGLAATALALALALLVNRILRGQFALAGEREQLIAERAEQAEAARRLARSKSDLVSTLSDEIRNGLTGVAHLLA
SAAGQGGRAAPSRQQVAAALDAVNDLLGVLDTTVDAETAEAGEIHVAPRPVDLVAVARDLLLAHRAAAAAKGLEIALHVD
AELAGDSGAAIADPLRARQALSALIANAVKFTLRGRVEVRLSRAGERRIAVAIADTGPGLSDEELATALQPFQRVARTSA
GAPGAGLGLPLACQLARLMGGEIRAQSAVGVGSCFTLELPYDPDVAASADAPQAAEPETRRLRVLLVEDDALGRATLRAT
LEQLGHQVVQAADRARAVELARVCDLDLAVVGAGSGGHETIAALRSLAGDAARTPVVAAIGGDPDEARACQAAGADALLR
KPVAVPAAARAIAQALSPRPSPANDRAVA
>Mature_588_residues
ADISQPADAGGVTVNEQALKAQAALLPYALAAFAVSLPVFVWAGSHAVNGAWMSASFALFAIGWGGFYAIVNWLKTPAAR
DLKTRGRVHVLGGLLWAATIAQLAAFADGAGPARETLLLLSLGAALICVFFAAPWLPSLLIVAPAAVAGPLVALFSRAAD
QPLAKLGLAATALALALALLVNRILRGQFALAGEREQLIAERAEQAEAARRLARSKSDLVSTLSDEIRNGLTGVAHLLAS
AAGQGGRAAPSRQQVAAALDAVNDLLGVLDTTVDAETAEAGEIHVAPRPVDLVAVARDLLLAHRAAAAAKGLEIALHVDA
ELAGDSGAAIADPLRARQALSALIANAVKFTLRGRVEVRLSRAGERRIAVAIADTGPGLSDEELATALQPFQRVARTSAG
APGAGLGLPLACQLARLMGGEIRAQSAVGVGSCFTLELPYDPDVAASADAPQAAEPETRRLRVLLVEDDALGRATLRATL
EQLGHQVVQAADRARAVELARVCDLDLAVVGAGSGGHETIAALRSLAGDAARTPVVAAIGGDPDEARACQAAGADALLRK
PVAVPAAARAIAQALSPRPSPANDRAVA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=384, Percent_Identity=29.6875, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788713, Length=389, Percent_Identity=26.2210796915167, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081816, Length=321, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1789149, Length=274, Percent_Identity=28.1021897810219, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=27.5, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87082128, Length=253, Percent_Identity=27.6679841897233, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60081; Mature: 59950

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADISQPADAGGVTVNEQALKAQAALLPYALAAFAVSLPVFVWAGSHAVNGAWMSASFAL
CCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHH
FAIGWGGFYAIVNWLKTPAARDLKTRGRVHVLGGLLWAATIAQLAAFADGAGPARETLLL
EEECHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LSLGAALICVFFAAPWLPSLLIVAPAAVAGPLVALFSRAADQPLAKLGLAATALALALAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVNRILRGQFALAGEREQLIAERAEQAEAARRLARSKSDLVSTLSDEIRNGLTGVAHLLA
HHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAGQGGRAAPSRQQVAAALDAVNDLLGVLDTTVDAETAEAGEIHVAPRPVDLVAVARDL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHH
LLAHRAAAAAKGLEIALHVDAELAGDSGAAIADPLRARQALSALIANAVKFTLRGRVEVR
HHHHHHHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LSRAGERRIAVAIADTGPGLSDEELATALQPFQRVARTSAGAPGAGLGLPLACQLARLMG
EECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
GEIRAQSAVGVGSCFTLELPYDPDVAASADAPQAAEPETRRLRVLLVEDDALGRATLRAT
CCHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHH
LEQLGHQVVQAADRARAVELARVCDLDLAVVGAGSGGHETIAALRSLAGDAARTPVVAAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEE
GGDPDEARACQAAGADALLRKPVAVPAAARAIAQALSPRPSPANDRAVA
CCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADISQPADAGGVTVNEQALKAQAALLPYALAAFAVSLPVFVWAGSHAVNGAWMSASFAL
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHH
FAIGWGGFYAIVNWLKTPAARDLKTRGRVHVLGGLLWAATIAQLAAFADGAGPARETLLL
EEECHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LSLGAALICVFFAAPWLPSLLIVAPAAVAGPLVALFSRAADQPLAKLGLAATALALALAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVNRILRGQFALAGEREQLIAERAEQAEAARRLARSKSDLVSTLSDEIRNGLTGVAHLLA
HHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAGQGGRAAPSRQQVAAALDAVNDLLGVLDTTVDAETAEAGEIHVAPRPVDLVAVARDL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHH
LLAHRAAAAAKGLEIALHVDAELAGDSGAAIADPLRARQALSALIANAVKFTLRGRVEVR
HHHHHHHHHHCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LSRAGERRIAVAIADTGPGLSDEELATALQPFQRVARTSAGAPGAGLGLPLACQLARLMG
EECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
GEIRAQSAVGVGSCFTLELPYDPDVAASADAPQAAEPETRRLRVLLVEDDALGRATLRAT
CCHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHH
LEQLGHQVVQAADRARAVELARVCDLDLAVVGAGSGGHETIAALRSLAGDAARTPVVAAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEE
GGDPDEARACQAAGADALLRKPVAVPAAARAIAQALSPRPSPANDRAVA
CCCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA