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The map label for this gene is fadB [H]

Identifier: 197104596

GI number: 197104596

Start: 1293152

End: 1293994

Strand: Direct

Name: fadB [H]

Synonym: PHZ_c1130

Alternate gene names: 197104596

Gene position: 1293152-1293994 (Clockwise)

Preceding gene: 197104595

Following gene: 197104598

Centisome position: 32.36

GC content: 73.19

Gene sequence:

>843_bases
ATGAACGACCGCGTGACCGTGGACATCCAGGACGGCGTCGCCGACGTGCGCCTGGTCCGCAGCGACAAGATGAACGCCCT
CGACGGCGCCATGTTCGACGCCCTGATCGAGACGGGCGAGCGGCTGAAGGGCGAGGCGGGCGTCCGCGCGGTGGTGATCT
CGGGCGAGGGCCGGGCGTTCTGCGCCGGCCTCGACATGGGCAACTTCCAGTCGATGGCCTCGGGCGAGCGCAAGGGCGGG
CAGGGCTCGGCCGGGGCGCTGCTGACCCGCGACCGCACGCCCGGGGGCTCGAACCGGGCGCAGCACGCCTGCATGGTCTG
GCGCGAGATTCCCGTGCCGGTGATCGCCGCCGTGCATGGCGTCGCGTTCGGCGGCGGATTCCAGCTCGCCCTGGGCGCGG
ACCTGCGGTTCGTCGCCCCCGACGCGCGCATGTCGGTCATGGAGATCAAGTGGGGCCTGGTGCCCGACATGGCGGGCATG
GTGCTGATGCGCGGCCTGGTGCGCGACGACCTCGCGCGCGAGCTCACCTGGAGCGGCCGGATCTTCGACGGACAGGAAGC
CGCGACGCTGGGCCTGGCCACCCGGGTCTGCGCCGACCCGCGCGCCGAGGCGCTGGCGTTCGCGCGCGACGTGGCCGGCA
AGAGCCCCGACGCGATCCGCGCGGGCAAGCGCCTGCTGAACCTGATGGGCCATGCGAGCCAGCACGAGATCCTGCTGGAG
GAGAGCCGCGAGCAGGCGGCCCTGATCGGCTCGCCCAACCAGGTCGAGGCGGTGATGGCCAACCTCCAGAAGCGGGCGCC
GGCGTTCGCCGACGGGGCCGCGCCCGAAAAGGCGGAGGTCTGA

Upstream 100 bases:

>100_bases
GCGGATCGTGATCGCCCGCGAGGGCGAGGGCCTCGGCCTCGTGCATGTGCATTTCCCGCGCGCCGGCTATGCGCTGGCCC
GGGCCTGAACGGAGAGACTG

Downstream 100 bases:

>100_bases
CGGCAGGCGACGGCTGGGGAGCGGGCGCGTCGCCGCCCGCTCCCGCCGCCCCCTTACCGCGACGCCAGCTTGGCGTTCGC
GGCCAGCTTGGCGGCCGCCG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNDRVTVDIQDGVADVRLVRSDKMNALDGAMFDALIETGERLKGEAGVRAVVISGEGRAFCAGLDMGNFQSMASGERKGG
QGSAGALLTRDRTPGGSNRAQHACMVWREIPVPVIAAVHGVAFGGGFQLALGADLRFVAPDARMSVMEIKWGLVPDMAGM
VLMRGLVRDDLARELTWSGRIFDGQEAATLGLATRVCADPRAEALAFARDVAGKSPDAIRAGKRLLNLMGHASQHEILLE
ESREQAALIGSPNQVEAVMANLQKRAPAFADGAAPEKAEV

Sequences:

>Translated_280_residues
MNDRVTVDIQDGVADVRLVRSDKMNALDGAMFDALIETGERLKGEAGVRAVVISGEGRAFCAGLDMGNFQSMASGERKGG
QGSAGALLTRDRTPGGSNRAQHACMVWREIPVPVIAAVHGVAFGGGFQLALGADLRFVAPDARMSVMEIKWGLVPDMAGM
VLMRGLVRDDLARELTWSGRIFDGQEAATLGLATRVCADPRAEALAFARDVAGKSPDAIRAGKRLLNLMGHASQHEILLE
ESREQAALIGSPNQVEAVMANLQKRAPAFADGAAPEKAEV
>Mature_280_residues
MNDRVTVDIQDGVADVRLVRSDKMNALDGAMFDALIETGERLKGEAGVRAVVISGEGRAFCAGLDMGNFQSMASGERKGG
QGSAGALLTRDRTPGGSNRAQHACMVWREIPVPVIAAVHGVAFGGGFQLALGADLRFVAPDARMSVMEIKWGLVPDMAGM
VLMRGLVRDDLARELTWSGRIFDGQEAATLGLATRVCADPRAEALAFARDVAGKSPDAIRAGKRLLNLMGHASQHEILLE
ESREQAALIGSPNQVEAVMANLQKRAPAFADGAAPEKAEV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=240, Percent_Identity=33.75, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI194097323, Length=267, Percent_Identity=25.0936329588015, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI68989263, Length=258, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4502327, Length=268, Percent_Identity=28.7313432835821, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31542718, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI221142681, Length=283, Percent_Identity=27.208480565371, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787659, Length=270, Percent_Identity=28.1481481481481, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790281, Length=204, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=238, Percent_Identity=28.9915966386555, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=273, Percent_Identity=24.9084249084249, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=274, Percent_Identity=27.7372262773723, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17554946, Length=263, Percent_Identity=26.9961977186312, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25145438, Length=264, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=230, Percent_Identity=27.3913043478261, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920382, Length=267, Percent_Identity=29.5880149812734, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653139, Length=273, Percent_Identity=26.7399267399267, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129971, Length=268, Percent_Identity=25.7462686567164, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653477, Length=268, Percent_Identity=25.7462686567164, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29618; Mature: 29618

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRVTVDIQDGVADVRLVRSDKMNALDGAMFDALIETGERLKGEAGVRAVVISGEGRAF
CCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
CAGLDMGNFQSMASGERKGGQGSAGALLTRDRTPGGSNRAQHACMVWREIPVPVIAAVHG
EEECCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
VAFGGGFQLALGADLRFVAPDARMSVMEIKWGLVPDMAGMVLMRGLVRDDLARELTWSGR
HEECCCEEEEECCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
IFDGQEAATLGLATRVCADPRAEALAFARDVAGKSPDAIRAGKRLLNLMGHASQHEILLE
EECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ESREQAALIGSPNQVEAVMANLQKRAPAFADGAAPEKAEV
HCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDRVTVDIQDGVADVRLVRSDKMNALDGAMFDALIETGERLKGEAGVRAVVISGEGRAF
CCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
CAGLDMGNFQSMASGERKGGQGSAGALLTRDRTPGGSNRAQHACMVWREIPVPVIAAVHG
EEECCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
VAFGGGFQLALGADLRFVAPDARMSVMEIKWGLVPDMAGMVLMRGLVRDDLARELTWSGR
HEECCCEEEEECCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
IFDGQEAATLGLATRVCADPRAEALAFARDVAGKSPDAIRAGKRLLNLMGHASQHEILLE
EECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ESREQAALIGSPNQVEAVMANLQKRAPAFADGAAPEKAEV
HCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]