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The map label for this gene is aacA4 [H]

Identifier: 197104577

GI number: 197104577

Start: 1266520

End: 1267017

Strand: Reverse

Name: aacA4 [H]

Synonym: PHZ_c1111

Alternate gene names: 197104577

Gene position: 1267017-1266520 (Counterclockwise)

Preceding gene: 197104578

Following gene: 197104572

Centisome position: 31.71

GC content: 72.49

Gene sequence:

>498_bases
GTGAGCGGGCAGATCGTCCTTCGCCCGGCCACGATGGACGACCTGGCGCTGCTGCGGCGCTGGGACGAGGAGCCCCATGT
GGTGGAGTCCGATCCCAACGACGACTGGGGCTGGGAGGTCGAGCTCGCCCGCGACCCCGACTGGCGCGAACAGCTCGTCG
CCGAGGCGGGCGGCCGTCCGGTCGGCTTCGTCCAGATCATCGACCCCGCGCGCGAGCAGAGCCGCTACTGGGGCGACTGT
CCGCCCGGCCTGCGCGCCATCGACATCTGGATCGGCGAGGCCGACGCGCTCGGCCGCGGCTACGGAACGCAGATGATGCG
GCAGGCGATCGCCCGCTGCTTCGCCGATGCGGCCGTCACGGCGATCCTGATCGACCCGCTGCAGAGCAACGTCCGGGCGA
TCCGCTTCTACGAGCGGCTGGGCTTCCGGGCCGTCGGTCCCCGCCGGTTCGGCGAGGACGACTGCCTGGTCATGCGCCTG
GAGCGGCCGGGCTCCTAG

Upstream 100 bases:

>100_bases
AGGTCACCGCCGCGGACGTGCAGGCCGCCGCCCAGCGCTGGCTGCGGGCCGAGCGCGCCTTCCGCCTGGTCGTGAAGCCG
GCCGCCCCCTTGAGCGGGAA

Downstream 100 bases:

>100_bases
GCGGCGGCCTTCTCGTCGCCGTAGACCGGCGCGTCCTCGGCCGGCAGGAAGGCCTTGCCGCGGATCGCGTCCGAGATCTT
CTCGGCGATCATGATGGTCG

Product: GCN5-related N-acetyltransferase

Products: NA

Alternate protein names: AAC(6'); Amikacin resistance protein [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSGQIVLRPATMDDLALLRRWDEEPHVVESDPNDDWGWEVELARDPDWREQLVAEAGGRPVGFVQIIDPAREQSRYWGDC
PPGLRAIDIWIGEADALGRGYGTQMMRQAIARCFADAAVTAILIDPLQSNVRAIRFYERLGFRAVGPRRFGEDDCLVMRL
ERPGS

Sequences:

>Translated_165_residues
MSGQIVLRPATMDDLALLRRWDEEPHVVESDPNDDWGWEVELARDPDWREQLVAEAGGRPVGFVQIIDPAREQSRYWGDC
PPGLRAIDIWIGEADALGRGYGTQMMRQAIARCFADAAVTAILIDPLQSNVRAIRFYERLGFRAVGPRRFGEDDCLVMRL
ERPGS
>Mature_164_residues
SGQIVLRPATMDDLALLRRWDEEPHVVESDPNDDWGWEVELARDPDWREQLVAEAGGRPVGFVQIIDPAREQSRYWGDCP
PGLRAIDIWIGEADALGRGYGTQMMRQAIARCFADAAVTAILIDPLQSNVRAIRFYERLGFRAVGPRRFGEDDCLVMRLE
RPGS

Specific function: Resistance to antibiotics containing the purpurosamine ring including gentamicin, kanamycin, tobramycin, and neomycin [H]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR019432 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF10331 AlcB [H]

EC number: =2.3.1.82 [H]

Molecular weight: Translated: 18667; Mature: 18536

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQIVLRPATMDDLALLRRWDEEPHVVESDPNDDWGWEVELARDPDWREQLVAEAGGRP
CCCCEEEECCCHHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCC
VGFVQIIDPAREQSRYWGDCPPGLRAIDIWIGEADALGRGYGTQMMRQAIARCFADAAVT
EEEEEEECCHHHHCCCCCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHH
AILIDPLQSNVRAIRFYERLGFRAVGPRRFGEDDCLVMRLERPGS
HHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
SGQIVLRPATMDDLALLRRWDEEPHVVESDPNDDWGWEVELARDPDWREQLVAEAGGRP
CCCEEEECCCHHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCC
VGFVQIIDPAREQSRYWGDCPPGLRAIDIWIGEADALGRGYGTQMMRQAIARCFADAAVT
EEEEEEECCHHHHCCCCCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHH
AILIDPLQSNVRAIRFYERLGFRAVGPRRFGEDDCLVMRLERPGS
HHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841303; 1963948 [H]