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The map label for this gene is cirA [H]

Identifier: 197104500

GI number: 197104500

Start: 1155090

End: 1157051

Strand: Direct

Name: cirA [H]

Synonym: PHZ_c1034

Alternate gene names: 197104500

Gene position: 1155090-1157051 (Clockwise)

Preceding gene: 197104499

Following gene: 197104501

Centisome position: 28.9

GC content: 72.63

Gene sequence:

>1962_bases
ATGCGGCGGAGAGGCGAGGGAGTCCGGACGCGGCTGGCGGCCGCGACGGCGGTCGCGGCGCTGGCCGGGGCGCTGGCCGG
GGCGGGGTTGACCGCCGGGACGGCGCAGGCGGAGGAGGCGGCCGCGCCGCCGGGACCCGCCCAGGCGCTGGGCGAGCTCT
CCATCGAGGAGCTGTCGCAGGTCAACGTGACCTCGGTCTCCAAGCGGCCCGAGCCGCTCGGCCACGCGGCGGCCTCCATC
TACCTGATCACCAACGAGGCCCTGCTGCGCTCGGGGGCGATGAGCCTGCCCGAGGCCCTGCGGCTCGCGCCCAACGTCGA
GGTGCTGCGGATCGACGCCCTGGACTATTCGATCAGCAGCCGCGGCTTCGCCGGCTTCGAGAGCTCGAACAAGCAGCTGG
TGCTGGTCGACGGGCGCAGCGTCTACACCCCGCTGTTCTCGGGCGTGGACTGGGACCAGCACCACCTCGTCATGGAGGAT
ATCGAGCGCATCGAGGTGATCAGCGGGCCGGGCGGGACGCTGTGGGGCGCGAACGCGGTGAACGGCGTCATCAACGTGGT
CAGCAAGAGCGCCTTCGACACCGACGGCCTGCTGGCGGCGGCCAACCTCGGGACGCTGGACAGCGACGTGCGGCTGCGCG
CGGGTCGCCCGCTGGGCGACATCGCCGCGGGCCGGGTCTACGTCACCGCCTTCCGGCGCGGCGACCTGGAGACGGCGGAC
GGCGCCGACGCCAACGACGGCTGGGACGGCTGGCAGGCCGGCTTCCGGGTCGACGTGGCGGGCGACCGCGACACCTTCAC
CCTGCAGGGCGACGTGCAGGACGCCGACATCCCCGAGAGCCTGGGATTCGCCTCGGGCTATGCGCGGGGCGGCAACCTGG
TGGCCCGCTGGACCCGGCGGACGGCCGGAGGGACACAGCTGGAGCTGCAGGGCTACTACGACGTCATGGAGCGCGAGGCG
CGCCAGGCCCATGACGAGCAGCGGGTCTGGGACGCGGCGCTGCAGGTCTCGCGGCCGATCGGGACGCGCCACCAGCTGGT
GGCCGGCGGCGGCTACCGGGTGACCAAGGACGAGTTCCGCACGCTCCTCGAGCCGCAGCTGCTGGCGACGCCGCGGCGCA
CGACCGAGATCGGCAACCTGTTCGTCGAGGACGAAATCGCCCTGACCCCCGAGCTGCTGCTGGCGGTGGGGGTGAAGCTG
GAGACGAACAGCTACACCAAGGCCGAATGGATGCCGAGCGCGCGGCTCGGCTGGCGGGTGAGCGAGCGGCAGTTCCTGTG
GGCCTCGGTGTCGCGGGCGGTGCGCAATCCCTCGCGCATCGAGCGGGACTTCACCATCGAGGGCCTGGTGCGGCCGGGCG
TGATGGGCTCGGAGAAGCTGATCGCCTACGAGGGCGGCTGGCGCGGGCGGCTGACGCCGCGGGCGACCGCCTCGATCACG
CTGTTCTATCACGACTACGACGACATCCGGACGAACGAGCTGACCCCGCCGGGGACCCTGCCGATCGTCGTCGGCAACGG
CATCGAGGGCGAGACCTGGGGCGTGGAGGCCTGGGCCGACGTGCAGGTCACCGACCGCTGGCGGCTGAGCGTCGGCGGCG
TGCGGCTGGAGAAGCAGTTCCGGATCAAGGACGGGGTCATCGACCTGTCGGGCTTCGAGGCCGCCGGCGCCGATCCCGCC
TGGTGGCTCAAGGCCAACTCGCACATCGACCTGACCGACCGGCTGAGCCTGGACGTCGGGGTTCGCGCCTTCGACGCCAT
CCCGCGCCTGGCGCCGGCCGACTACGTGGGCGCGGATGGCTATGTGGAGGCCCAGGCGCGGCTCGCCTTCAAGGTGCGCG
AGGACCTGGAGCTGTCGCTCACCGGCCTGAACCTGCTGCACGCCCGCCACGCCGAGGCCAGCGAGGCGCGGCGCAACGAA
ATCCCGCGCAGCGTCCACGTCGGCCTGCGCTGGATGCGCTGA

Upstream 100 bases:

>100_bases
GCGGGAGCTTCGGCGTTCCGGTGACGGTGAAGCTTTTTTCGCCCTCGTGCGTTTGAACACGACCGGCGGCGCGGGGGCGC
CGCCCGAGCAAGGGGGGGTC

Downstream 100 bases:

>100_bases
TGGGAGCACCCGCCCGGACCCGGCTGGCGGCGGCCGCGCTCGCGGCGGCGGCCCTCGCGCCCGCGGCGGCCGGCGCGCAG
CCGCTGGAGACGCAGGTGAA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MRRRGEGVRTRLAAATAVAALAGALAGAGLTAGTAQAEEAAAPPGPAQALGELSIEELSQVNVTSVSKRPEPLGHAAASI
YLITNEALLRSGAMSLPEALRLAPNVEVLRIDALDYSISSRGFAGFESSNKQLVLVDGRSVYTPLFSGVDWDQHHLVMED
IERIEVISGPGGTLWGANAVNGVINVVSKSAFDTDGLLAAANLGTLDSDVRLRAGRPLGDIAAGRVYVTAFRRGDLETAD
GADANDGWDGWQAGFRVDVAGDRDTFTLQGDVQDADIPESLGFASGYARGGNLVARWTRRTAGGTQLELQGYYDVMEREA
RQAHDEQRVWDAALQVSRPIGTRHQLVAGGGYRVTKDEFRTLLEPQLLATPRRTTEIGNLFVEDEIALTPELLLAVGVKL
ETNSYTKAEWMPSARLGWRVSERQFLWASVSRAVRNPSRIERDFTIEGLVRPGVMGSEKLIAYEGGWRGRLTPRATASIT
LFYHDYDDIRTNELTPPGTLPIVVGNGIEGETWGVEAWADVQVTDRWRLSVGGVRLEKQFRIKDGVIDLSGFEAAGADPA
WWLKANSHIDLTDRLSLDVGVRAFDAIPRLAPADYVGADGYVEAQARLAFKVREDLELSLTGLNLLHARHAEASEARRNE
IPRSVHVGLRWMR

Sequences:

>Translated_653_residues
MRRRGEGVRTRLAAATAVAALAGALAGAGLTAGTAQAEEAAAPPGPAQALGELSIEELSQVNVTSVSKRPEPLGHAAASI
YLITNEALLRSGAMSLPEALRLAPNVEVLRIDALDYSISSRGFAGFESSNKQLVLVDGRSVYTPLFSGVDWDQHHLVMED
IERIEVISGPGGTLWGANAVNGVINVVSKSAFDTDGLLAAANLGTLDSDVRLRAGRPLGDIAAGRVYVTAFRRGDLETAD
GADANDGWDGWQAGFRVDVAGDRDTFTLQGDVQDADIPESLGFASGYARGGNLVARWTRRTAGGTQLELQGYYDVMEREA
RQAHDEQRVWDAALQVSRPIGTRHQLVAGGGYRVTKDEFRTLLEPQLLATPRRTTEIGNLFVEDEIALTPELLLAVGVKL
ETNSYTKAEWMPSARLGWRVSERQFLWASVSRAVRNPSRIERDFTIEGLVRPGVMGSEKLIAYEGGWRGRLTPRATASIT
LFYHDYDDIRTNELTPPGTLPIVVGNGIEGETWGVEAWADVQVTDRWRLSVGGVRLEKQFRIKDGVIDLSGFEAAGADPA
WWLKANSHIDLTDRLSLDVGVRAFDAIPRLAPADYVGADGYVEAQARLAFKVREDLELSLTGLNLLHARHAEASEARRNE
IPRSVHVGLRWMR
>Mature_653_residues
MRRRGEGVRTRLAAATAVAALAGALAGAGLTAGTAQAEEAAAPPGPAQALGELSIEELSQVNVTSVSKRPEPLGHAAASI
YLITNEALLRSGAMSLPEALRLAPNVEVLRIDALDYSISSRGFAGFESSNKQLVLVDGRSVYTPLFSGVDWDQHHLVMED
IERIEVISGPGGTLWGANAVNGVINVVSKSAFDTDGLLAAANLGTLDSDVRLRAGRPLGDIAAGRVYVTAFRRGDLETAD
GADANDGWDGWQAGFRVDVAGDRDTFTLQGDVQDADIPESLGFASGYARGGNLVARWTRRTAGGTQLELQGYYDVMEREA
RQAHDEQRVWDAALQVSRPIGTRHQLVAGGGYRVTKDEFRTLLEPQLLATPRRTTEIGNLFVEDEIALTPELLLAVGVKL
ETNSYTKAEWMPSARLGWRVSERQFLWASVSRAVRNPSRIERDFTIEGLVRPGVMGSEKLIAYEGGWRGRLTPRATASIT
LFYHDYDDIRTNELTPPGTLPIVVGNGIEGETWGVEAWADVQVTDRWRLSVGGVRLEKQFRIKDGVIDLSGFEAAGADPA
WWLKANSHIDLTDRLSLDVGVRAFDAIPRLAPADYVGADGYVEAQARLAFKVREDLELSLTGLNLLHARHAEASEARRNE
IPRSVHVGLRWMR

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 70931; Mature: 70931

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRGEGVRTRLAAATAVAALAGALAGAGLTAGTAQAEEAAAPPGPAQALGELSIEELSQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHCCCHHHHHC
VNVTSVSKRPEPLGHAAASIYLITNEALLRSGAMSLPEALRLAPNVEVLRIDALDYSISS
CCEEECCCCCCCCCCCEEEEEEEECHHHHHCCCCCCCHHHHCCCCCEEEEEEEECCCCCC
RGFAGFESSNKQLVLVDGRSVYTPLFSGVDWDQHHLVMEDIERIEVISGPGGTLWGANAV
CCCCCCCCCCCEEEEECCCEEEHHHHCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCHHH
NGVINVVSKSAFDTDGLLAAANLGTLDSDVRLRAGRPLGDIAAGRVYVTAFRRGDLETAD
HHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHCCCEEEEEEEECCCCCCCC
GADANDGWDGWQAGFRVDVAGDRDTFTLQGDVQDADIPESLGFASGYARGGNLVARWTRR
CCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCEEEEEECC
TAGGTQLELQGYYDVMEREARQAHDEQRVWDAALQVSRPIGTRHQLVAGGGYRVTKDEFR
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECHHHHH
TLLEPQLLATPRRTTEIGNLFVEDEIALTPELLLAVGVKLETNSYTKAEWMPSARLGWRV
HHCCCHHHCCCCCCHHHCCEEEECCCCCCHHHHHHCCCEEECCCCCCHHCCCCCCCCEEE
SERQFLWASVSRAVRNPSRIERDFTIEGLVRPGVMGSEKLIAYEGGWRGRLTPRATASIT
CCCHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEEE
LFYHDYDDIRTNELTPPGTLPIVVGNGIEGETWGVEAWADVQVTDRWRLSVGGVRLEKQF
EEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEECEEEEEECCEEEEEEE
RIKDGVIDLSGFEAAGADPAWWLKANSHIDLTDRLSLDVGVRAFDAIPRLAPADYVGADG
EEECCEEEECCCCCCCCCCEEEEEECCEECCHHCCEEECCCHHHHHCCCCCCCCCCCCCC
YVEAQARLAFKVREDLELSLTGLNLLHARHAEASEARRNEIPRSVHVGLRWMR
EEEEEEEEEEEECCCCEEEEECCHHHHHHCCCHHHHHHHCCCCEEECCEEECC
>Mature Secondary Structure
MRRRGEGVRTRLAAATAVAALAGALAGAGLTAGTAQAEEAAAPPGPAQALGELSIEELSQ
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHCCCHHHHHC
VNVTSVSKRPEPLGHAAASIYLITNEALLRSGAMSLPEALRLAPNVEVLRIDALDYSISS
CCEEECCCCCCCCCCCEEEEEEEECHHHHHCCCCCCCHHHHCCCCCEEEEEEEECCCCCC
RGFAGFESSNKQLVLVDGRSVYTPLFSGVDWDQHHLVMEDIERIEVISGPGGTLWGANAV
CCCCCCCCCCCEEEEECCCEEEHHHHCCCCCCCCHHHHHHHHHEEEEECCCCCCCCCHHH
NGVINVVSKSAFDTDGLLAAANLGTLDSDVRLRAGRPLGDIAAGRVYVTAFRRGDLETAD
HHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHCCCEEEEEEEECCCCCCCC
GADANDGWDGWQAGFRVDVAGDRDTFTLQGDVQDADIPESLGFASGYARGGNLVARWTRR
CCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCEEEEEECC
TAGGTQLELQGYYDVMEREARQAHDEQRVWDAALQVSRPIGTRHQLVAGGGYRVTKDEFR
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECHHHHH
TLLEPQLLATPRRTTEIGNLFVEDEIALTPELLLAVGVKLETNSYTKAEWMPSARLGWRV
HHCCCHHHCCCCCCHHHCCEEEECCCCCCHHHHHHCCCEEECCCCCCHHCCCCCCCCEEE
SERQFLWASVSRAVRNPSRIERDFTIEGLVRPGVMGSEKLIAYEGGWRGRLTPRATASIT
CCCHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEEE
LFYHDYDDIRTNELTPPGTLPIVVGNGIEGETWGVEAWADVQVTDRWRLSVGGVRLEKQF
EEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEECEEEEEECCEEEEEEE
RIKDGVIDLSGFEAAGADPAWWLKANSHIDLTDRLSLDVGVRAFDAIPRLAPADYVGADG
EEECCEEEECCCCCCCCCCEEEEEECCEECCHHCCEEECCCHHHHHCCCCCCCCCCCCCC
YVEAQARLAFKVREDLELSLTGLNLLHARHAEASEARRNEIPRSVHVGLRWMR
EEEEEEEEEEEECCCCEEEEECCHHHHHHCCCHHHHHHHCCCCEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]