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The map label for this gene is luxQ [H]

Identifier: 197104499

GI number: 197104499

Start: 1151940

End: 1154441

Strand: Direct

Name: luxQ [H]

Synonym: PHZ_c1033

Alternate gene names: 197104499

Gene position: 1151940-1154441 (Clockwise)

Preceding gene: 197104496

Following gene: 197104500

Centisome position: 28.83

GC content: 73.5

Gene sequence:

>2502_bases
ATGGTGACCGCGTTCCCCCCGCTCGCGCCCGCCGGCGCGGCCCTGTTGTGGCGCATCGCCCTGCTGGTCGCGGTGGTGGC
GGGCCTGTCGTACGTCGGCATGGTCGCGCCCAAGGAAGCCGGCAAGGTGGCCCCGATCTGGCTGGCTAACGCCCCGGTGC
TGGCCTGCCTGCTGCGGGCCCCGGTCCGGAACTGGTGGATCTGGGTGGCCGCGGGCCTGGCCGGCAGCCTCGCGGGAGAG
ATCGCGGCGGGCGGGCGGCTGGAGCCCAGCGTGGCGCTGTCGCTGTGCAGCAGCCTGGAGGTCGTGCTGTGCGCGACGGT
GGCGGGCAAGCTGATCGGCGGCCAGATGGACGTGACCCGCGCCTGGCACCTGGCCGCCATGGCCCTTTCGGCCTGCCTGT
CGGCGGTGATCTCGGCGACGCTGGCCTCAAGCTACCTCGGGCTGATGGGCGAGGGACGGTTCCTCGACCACCTGATGCTC
TGGTCGGTGTCGAACGCCCTGGGGCTGACGCTGCTGACGCCATGCCTGCTGGTGCTGGTGGAGTGGCGGGGCTGGCTGGC
GGAACGGCCGATGTCGCGCGCCGGGGCGGCCTCGCTGACCGGACTGGCGGGCCTGGCGGTGGCCGTGTTCGGCCAGGACA
GCTGGCCGCTGACCTTCCTGATCCCGCCCGCGATCCTGGTCGCCTGCCTGACGCTGGAGATGTTCGGCGCGGCGGTGGCT
GTGATGCTGACCTGTTCGATCGCGGTGGGCTTCACGCTGAAGGACCACGGCCCGCTGGCCATGACGAGCGGCGGCTGGAC
CGCGCGGCTGATGGTGCTGCAGCTGTTCCTGCTGGTGGACGCGCTGCTGGCCTTCCAGGTGGCGGCCCTGCTGCGCAACC
GGCGGCTGATGCGCGAGGAGCTGGAGGCGGCCCGCCAGGAGGCCGAGGCGCGCGCCGCCGACGCCGAGGAGGCCAAGTCG
CAGTACCGGCTGCTGGCCGAGCGGGTCACCGACGTGATGAGCCGCTCCACGGTGACGGGGCAGATCACCTACCTGTCGCC
CAGCGTGGTCAAGCTCTCGGGCTTCTCGCCCGAGGACCTGGTGGGGCAGCAGATGCTGGAGGGCGTCCATCCCGAGGACC
AGGCCGCCTTCCTGCACGCGCACATGGACATGCTGCGCGGCCGCCGCGCGCCGGGAACGCCGATCCGCTACCGGGTCGCC
TGCAAGACCGGCGGCTGGGTGTGGATCGAGGGCAACCCCTCGCTGGTGCGCGACGAGCGGGGGCGTCCCGTCGAGTTCGT
GGACGTCTCGCGCAACGTGACCGAGCGGGTCGAGCTGGAGGCGCGGCTGGCGGCGGCGGTGGCCGAGGCCGAGCGGGCGG
CGACGGTGAAGTCGGACTTCCTGGCCAACATGAGCCACGAGATCCGCACGCCGCTGACCTCGATCCTGGGGTTCGCCTCG
TTCCTGGACGAGCTGAAGCTGCCCGAGCCGGCGGGGGGCTACGCCGCCAAGGTGACGACCGCCAGCCGCACGCTGCTGGC
CATCGTCAACGACGTGCTGGACTTCTCGAAGCTGGAGGCCGGGCGGCTGGAGATGAAGCCGCGGCCCACCGACCCGGCCG
AGTGCGCGCGCGACGTGCTGGACCTGTTCGGGCCGCAGGCGCAGGCCAAGGGGCTGGAGCTGGTGCTGGAGCCGGCGGCG
CCGGCCGTGGCGATGATCGACGCCGACCGGCTGCGGCAGGTGCTGATGAACCTGGTCGGCAATGCGGTGAAGTTCACCCA
GTCGGGCTCGGTGCGGCTGTCGTGCGCCTACGATCCGGCCGAGCGGCGGCTGACCTGCAAGGTGGCCGACACCGGGCCCG
GGATCGGGGCCGCGGCGATGGAGAAGCTGTTCCAGCGCTTCAGCCAGGTGGACGGCTCGACGACCCGGGCGCACGGCGGG
ACGGGCCTGGGGCTGGCGATCAGCAAGGGCCTGGTCGAGGCCATGGGCGGGCGGATCGGGGTGGAGAGCGCGCCGGGCCG
CGGCTCGACGTTCTGGTTCGAGGCCCCGGCCGAGCCGGCCGCGGCGGCGCCGGCCGAGGCCGACGAGGCGCCGGACGTGC
AGGTGATGGCCGGGGTGCGGGTGCTGGCCGCCGACGACAATCCGCAGAACCTGGAGATCGTCCGCTCGATCCTGACGCCG
CTGGGGGTGGACCTGACCGAGGCCCAGAGCGGGGCCGAGGCGGTGGAGGCGGCGCGCCTGGCGCCCTTCGACGTGATCCT
GATGGACCTGCGGATGCCGGGGGTGGACGGCTGGGCGGCGGCGAACGCGATCCGGGAAGGCCACGGGCCGAACCGCGACG
CCCCGATTCTGGCGTTCTCGGCCGACGTGGCGCCCGACCGGCGCGAGGCGATGGGCGTGTTCCAGGACCTGGTCAGCAAG
CCGATCGAGCCGCCGGCGCTCCTGCGGGCGATCCTGCGCTGGACGCTGGCGGAACCGGCGGCGGCGGACGGCGAGGAGTC
CTCGGGACGGGCGGCCGGTTGA

Upstream 100 bases:

>100_bases
CAGTCCGGGGGCGGCTGGCCGGCGCGGGCGCGGAGCTAAAGCCGCCCCCGCTGCCCCCGCGTTAACGGAATAGAGGGGCG
TTGCGCGGTCCAGTTGAGGG

Downstream 100 bases:

>100_bases
GGCCGGGCGGAACAAAACCGACGCGGGAACATCATTTGCAGTTGTCAAGCTGGCGGCGGCGCGCTTCGCTCGTCGGTTCG
AAGAAGGCCTCACGCATGAA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 833; Mature: 833

Protein sequence:

>833_residues
MVTAFPPLAPAGAALLWRIALLVAVVAGLSYVGMVAPKEAGKVAPIWLANAPVLACLLRAPVRNWWIWVAAGLAGSLAGE
IAAGGRLEPSVALSLCSSLEVVLCATVAGKLIGGQMDVTRAWHLAAMALSACLSAVISATLASSYLGLMGEGRFLDHLML
WSVSNALGLTLLTPCLLVLVEWRGWLAERPMSRAGAASLTGLAGLAVAVFGQDSWPLTFLIPPAILVACLTLEMFGAAVA
VMLTCSIAVGFTLKDHGPLAMTSGGWTARLMVLQLFLLVDALLAFQVAALLRNRRLMREELEAARQEAEARAADAEEAKS
QYRLLAERVTDVMSRSTVTGQITYLSPSVVKLSGFSPEDLVGQQMLEGVHPEDQAAFLHAHMDMLRGRRAPGTPIRYRVA
CKTGGWVWIEGNPSLVRDERGRPVEFVDVSRNVTERVELEARLAAAVAEAERAATVKSDFLANMSHEIRTPLTSILGFAS
FLDELKLPEPAGGYAAKVTTASRTLLAIVNDVLDFSKLEAGRLEMKPRPTDPAECARDVLDLFGPQAQAKGLELVLEPAA
PAVAMIDADRLRQVLMNLVGNAVKFTQSGSVRLSCAYDPAERRLTCKVADTGPGIGAAAMEKLFQRFSQVDGSTTRAHGG
TGLGLAISKGLVEAMGGRIGVESAPGRGSTFWFEAPAEPAAAAPAEADEAPDVQVMAGVRVLAADDNPQNLEIVRSILTP
LGVDLTEAQSGAEAVEAARLAPFDVILMDLRMPGVDGWAAANAIREGHGPNRDAPILAFSADVAPDRREAMGVFQDLVSK
PIEPPALLRAILRWTLAEPAAADGEESSGRAAG

Sequences:

>Translated_833_residues
MVTAFPPLAPAGAALLWRIALLVAVVAGLSYVGMVAPKEAGKVAPIWLANAPVLACLLRAPVRNWWIWVAAGLAGSLAGE
IAAGGRLEPSVALSLCSSLEVVLCATVAGKLIGGQMDVTRAWHLAAMALSACLSAVISATLASSYLGLMGEGRFLDHLML
WSVSNALGLTLLTPCLLVLVEWRGWLAERPMSRAGAASLTGLAGLAVAVFGQDSWPLTFLIPPAILVACLTLEMFGAAVA
VMLTCSIAVGFTLKDHGPLAMTSGGWTARLMVLQLFLLVDALLAFQVAALLRNRRLMREELEAARQEAEARAADAEEAKS
QYRLLAERVTDVMSRSTVTGQITYLSPSVVKLSGFSPEDLVGQQMLEGVHPEDQAAFLHAHMDMLRGRRAPGTPIRYRVA
CKTGGWVWIEGNPSLVRDERGRPVEFVDVSRNVTERVELEARLAAAVAEAERAATVKSDFLANMSHEIRTPLTSILGFAS
FLDELKLPEPAGGYAAKVTTASRTLLAIVNDVLDFSKLEAGRLEMKPRPTDPAECARDVLDLFGPQAQAKGLELVLEPAA
PAVAMIDADRLRQVLMNLVGNAVKFTQSGSVRLSCAYDPAERRLTCKVADTGPGIGAAAMEKLFQRFSQVDGSTTRAHGG
TGLGLAISKGLVEAMGGRIGVESAPGRGSTFWFEAPAEPAAAAPAEADEAPDVQVMAGVRVLAADDNPQNLEIVRSILTP
LGVDLTEAQSGAEAVEAARLAPFDVILMDLRMPGVDGWAAANAIREGHGPNRDAPILAFSADVAPDRREAMGVFQDLVSK
PIEPPALLRAILRWTLAEPAAADGEESSGRAAG
>Mature_833_residues
MVTAFPPLAPAGAALLWRIALLVAVVAGLSYVGMVAPKEAGKVAPIWLANAPVLACLLRAPVRNWWIWVAAGLAGSLAGE
IAAGGRLEPSVALSLCSSLEVVLCATVAGKLIGGQMDVTRAWHLAAMALSACLSAVISATLASSYLGLMGEGRFLDHLML
WSVSNALGLTLLTPCLLVLVEWRGWLAERPMSRAGAASLTGLAGLAVAVFGQDSWPLTFLIPPAILVACLTLEMFGAAVA
VMLTCSIAVGFTLKDHGPLAMTSGGWTARLMVLQLFLLVDALLAFQVAALLRNRRLMREELEAARQEAEARAADAEEAKS
QYRLLAERVTDVMSRSTVTGQITYLSPSVVKLSGFSPEDLVGQQMLEGVHPEDQAAFLHAHMDMLRGRRAPGTPIRYRVA
CKTGGWVWIEGNPSLVRDERGRPVEFVDVSRNVTERVELEARLAAAVAEAERAATVKSDFLANMSHEIRTPLTSILGFAS
FLDELKLPEPAGGYAAKVTTASRTLLAIVNDVLDFSKLEAGRLEMKPRPTDPAECARDVLDLFGPQAQAKGLELVLEPAA
PAVAMIDADRLRQVLMNLVGNAVKFTQSGSVRLSCAYDPAERRLTCKVADTGPGIGAAAMEKLFQRFSQVDGSTTRAHGG
TGLGLAISKGLVEAMGGRIGVESAPGRGSTFWFEAPAEPAAAAPAEADEAPDVQVMAGVRVLAADDNPQNLEIVRSILTP
LGVDLTEAQSGAEAVEAARLAPFDVILMDLRMPGVDGWAAANAIREGHGPNRDAPILAFSADVAPDRREAMGVFQDLVSK
PIEPPALLRAILRWTLAEPAAADGEESSGRAAG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=410, Percent_Identity=34.6341463414634, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1789149, Length=301, Percent_Identity=39.202657807309, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1788713, Length=366, Percent_Identity=31.9672131147541, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI87081816, Length=391, Percent_Identity=33.7595907928389, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI145693157, Length=320, Percent_Identity=34.6875, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=33.6206896551724, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=30.9322033898305, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788549, Length=394, Percent_Identity=25.8883248730964, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=299, Percent_Identity=29.4314381270903, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=32.0675105485232, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=26.8722466960352, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=31.7307692307692, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=27.8026905829596, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789808, Length=242, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88026; Mature: 88026

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTAFPPLAPAGAALLWRIALLVAVVAGLSYVGMVAPKEAGKVAPIWLANAPVLACLLRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHH
PVRNWWIWVAAGLAGSLAGEIAAGGRLEPSVALSLCSSLEVVLCATVAGKLIGGQMDVTR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AWHLAAMALSACLSAVISATLASSYLGLMGEGRFLDHLMLWSVSNALGLTLLTPCLLVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWRGWLAERPMSRAGAASLTGLAGLAVAVFGQDSWPLTFLIPPAILVACLTLEMFGAAVA
HHHHHHHHCCCHHCCCHHHHHHHHHHHEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHH
VMLTCSIAVGFTLKDHGPLAMTSGGWTARLMVLQLFLLVDALLAFQVAALLRNRRLMREE
HHHHHHHHEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAARQEAEARAADAEEAKSQYRLLAERVTDVMSRSTVTGQITYLSPSVVKLSGFSPEDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHH
VGQQMLEGVHPEDQAAFLHAHMDMLRGRRAPGTPIRYRVACKTGGWVWIEGNPSLVRDER
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCEECCCC
GRPVEFVDVSRNVTERVELEARLAAAVAEAERAATVKSDFLANMSHEIRTPLTSILGFAS
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLDELKLPEPAGGYAAKVTTASRTLLAIVNDVLDFSKLEAGRLEMKPRPTDPAECARDVL
HHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHH
DLFGPQAQAKGLELVLEPAAPAVAMIDADRLRQVLMNLVGNAVKFTQSGSVRLSCAYDPA
HHHCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCC
ERRLTCKVADTGPGIGAAAMEKLFQRFSQVDGSTTRAHGGTGLGLAISKGLVEAMGGRIG
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
VESAPGRGSTFWFEAPAEPAAAAPAEADEAPDVQVMAGVRVLAADDNPQNLEIVRSILTP
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECEEEEEECCCCCHHHHHHHHHHH
LGVDLTEAQSGAEAVEAARLAPFDVILMDLRMPGVDGWAAANAIREGHGPNRDAPILAFS
CCCCHHHHHCCHHHHHHHHCCCHHHHEEEHCCCCCCCHHHHHHHHHCCCCCCCCCEEEEE
ADVAPDRREAMGVFQDLVSKPIEPPALLRAILRWTLAEPAAADGEESSGRAAG
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVTAFPPLAPAGAALLWRIALLVAVVAGLSYVGMVAPKEAGKVAPIWLANAPVLACLLRA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHH
PVRNWWIWVAAGLAGSLAGEIAAGGRLEPSVALSLCSSLEVVLCATVAGKLIGGQMDVTR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AWHLAAMALSACLSAVISATLASSYLGLMGEGRFLDHLMLWSVSNALGLTLLTPCLLVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWRGWLAERPMSRAGAASLTGLAGLAVAVFGQDSWPLTFLIPPAILVACLTLEMFGAAVA
HHHHHHHHCCCHHCCCHHHHHHHHHHHEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHH
VMLTCSIAVGFTLKDHGPLAMTSGGWTARLMVLQLFLLVDALLAFQVAALLRNRRLMREE
HHHHHHHHEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAARQEAEARAADAEEAKSQYRLLAERVTDVMSRSTVTGQITYLSPSVVKLSGFSPEDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHH
VGQQMLEGVHPEDQAAFLHAHMDMLRGRRAPGTPIRYRVACKTGGWVWIEGNPSLVRDER
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCEECCCC
GRPVEFVDVSRNVTERVELEARLAAAVAEAERAATVKSDFLANMSHEIRTPLTSILGFAS
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLDELKLPEPAGGYAAKVTTASRTLLAIVNDVLDFSKLEAGRLEMKPRPTDPAECARDVL
HHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHH
DLFGPQAQAKGLELVLEPAAPAVAMIDADRLRQVLMNLVGNAVKFTQSGSVRLSCAYDPA
HHHCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCC
ERRLTCKVADTGPGIGAAAMEKLFQRFSQVDGSTTRAHGGTGLGLAISKGLVEAMGGRIG
CCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
VESAPGRGSTFWFEAPAEPAAAAPAEADEAPDVQVMAGVRVLAADDNPQNLEIVRSILTP
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECEEEEEECCCCCHHHHHHHHHHH
LGVDLTEAQSGAEAVEAARLAPFDVILMDLRMPGVDGWAAANAIREGHGPNRDAPILAFS
CCCCHHHHHCCHHHHHHHHCCCHHHHEEEHCCCCCCCHHHHHHHHHCCCCCCCCCEEEEE
ADVAPDRREAMGVFQDLVSKPIEPPALLRAILRWTLAEPAAADGEESSGRAAG
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]