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The map label for this gene is hflK [H]

Identifier: 197104344

GI number: 197104344

Start: 971009

End: 972154

Strand: Reverse

Name: hflK [H]

Synonym: PHZ_c0878

Alternate gene names: 197104344

Gene position: 972154-971009 (Counterclockwise)

Preceding gene: 197104346

Following gene: 197104343

Centisome position: 24.33

GC content: 72.51

Gene sequence:

>1146_bases
ATGCCCTGGAACGATAACGCCAATCCCGGCCCGTGGGGCTCGCCCCCGTCCGGCGACGGCGACCGCCGAGACAACACCCC
CAAGCGCCCGCGCGGCGGCGGACCCCGCCGTCCCGAAGGCCCCGACTTCAACGCCAACTTCGACCGGCTGGGCCGGCGGC
TGCGCGACTTCTTCAGCGGCGGCCCCGGCGGCGGGGTCCGGCCCGGCGCGATCGCCGCGGTCGTGGGCGCGGCCTTCGGC
CTGTGGGCGCTGTCGGGGATCTACGTGGTCCAGCCGAACGAGGAGGCCGTGGTCACCACCTTCGGCGCCTATTCGCGCAA
CGAGGGCCCCGGCCTGCGCTACCACCTGCCCGCTCCTATCGAGCGCGTGCAGAAGGTGCCGGTCACCAGCCTGCAGCGGC
TGGACGTGGGCGGCGCCGCCGCCGGCGCGGTGCCGGAAGAGAGCCTGATGCTCACCGGCGACGAGAACATCATCGACCTG
CAATTCAGCGTCACCTGGCGCGTCGCCGACGCCGACCGCTTCGTCTTCACCATCCGCGACCCCGAAGGCTCGGTGAAGGC
GGTGGCGGAGAGCGCCATGCGCGAGGTCGTCGGCCGCACCAACCTGCTGGACATCCTCACCACCGGCCGCGGCCAGGTGC
AGCAGCAGGCGGCCGAACTGATGCAGCGGACCCTGGATTCCTGGGGCGCCGGCGTGCGCATCGACGAGGTGCAGATCCGC
TCGGCCAACCCGCCGCAGCAGGTGCTGGCGGCGTTCCGCGACGTGGTCAGCGCCCAGCAGGACCAGGAGTCGGCGGTCAA
CGAGGCCAACACCTACCGCAACCGGGTGATCAACGAGGCCAAGGGCGACGCCGCGCGCATCGTGCAGGCCGCCCAGGCCT
ACCGCGAGCAGGCCGTGCGCGAGGCCACCGGCGATGCGTCCCGCTTCAACGCCATCCTGAACGAATACCGCCGCGCTCCG
GGCGCCACCCGGGACCGGATCTACATCGAGACCATGCAGCGCGTGCTCGCCCGTTCGAACAAGGTGATCGTCGACAGCGA
AGGCGCCTCCGCGCCGATCATCCTGCCGCCCGACGTGTTCCGGCCCAGGACCCAGCCGCAGGCGCCCGCGCCGCAGGCCG
TCCCGCAGACGGAGGCCGCCCAATGA

Upstream 100 bases:

>100_bases
AGGGGCCTCATATCCGGCTGGAAGCGCCGGTTTACAAGCCCATGCAGGGCTTTAAGCAGAGGACCGCTAGGCCCCACTTG
AGTACGACGCGACCTGGCTG

Downstream 100 bases:

>100_bases
GCCGCCGTCTCTGGACCTACCTGATCGTCGGGATCGGCGCCCTCGTGGTGCTGGCCAACACCCTCTACATCGTCGACCAG
CGCGAGCAGGCGATCGTGCT

Product: protease subunit hflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MPWNDNANPGPWGSPPSGDGDRRDNTPKRPRGGGPRRPEGPDFNANFDRLGRRLRDFFSGGPGGGVRPGAIAAVVGAAFG
LWALSGIYVVQPNEEAVVTTFGAYSRNEGPGLRYHLPAPIERVQKVPVTSLQRLDVGGAAAGAVPEESLMLTGDENIIDL
QFSVTWRVADADRFVFTIRDPEGSVKAVAESAMREVVGRTNLLDILTTGRGQVQQQAAELMQRTLDSWGAGVRIDEVQIR
SANPPQQVLAAFRDVVSAQQDQESAVNEANTYRNRVINEAKGDAARIVQAAQAYREQAVREATGDASRFNAILNEYRRAP
GATRDRIYIETMQRVLARSNKVIVDSEGASAPIILPPDVFRPRTQPQAPAPQAVPQTEAAQ

Sequences:

>Translated_381_residues
MPWNDNANPGPWGSPPSGDGDRRDNTPKRPRGGGPRRPEGPDFNANFDRLGRRLRDFFSGGPGGGVRPGAIAAVVGAAFG
LWALSGIYVVQPNEEAVVTTFGAYSRNEGPGLRYHLPAPIERVQKVPVTSLQRLDVGGAAAGAVPEESLMLTGDENIIDL
QFSVTWRVADADRFVFTIRDPEGSVKAVAESAMREVVGRTNLLDILTTGRGQVQQQAAELMQRTLDSWGAGVRIDEVQIR
SANPPQQVLAAFRDVVSAQQDQESAVNEANTYRNRVINEAKGDAARIVQAAQAYREQAVREATGDASRFNAILNEYRRAP
GATRDRIYIETMQRVLARSNKVIVDSEGASAPIILPPDVFRPRTQPQAPAPQAVPQTEAAQ
>Mature_380_residues
PWNDNANPGPWGSPPSGDGDRRDNTPKRPRGGGPRRPEGPDFNANFDRLGRRLRDFFSGGPGGGVRPGAIAAVVGAAFGL
WALSGIYVVQPNEEAVVTTFGAYSRNEGPGLRYHLPAPIERVQKVPVTSLQRLDVGGAAAGAVPEESLMLTGDENIIDLQ
FSVTWRVADADRFVFTIRDPEGSVKAVAESAMREVVGRTNLLDILTTGRGQVQQQAAELMQRTLDSWGAGVRIDEVQIRS
ANPPQQVLAAFRDVVSAQQDQESAVNEANTYRNRVINEAKGDAARIVQAAQAYREQAVREATGDASRFNAILNEYRRAPG
ATRDRIYIETMQRVLARSNKVIVDSEGASAPIILPPDVFRPRTQPQAPAPQAVPQTEAAQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=274, Percent_Identity=35.036496350365, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 41237; Mature: 41105

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWNDNANPGPWGSPPSGDGDRRDNTPKRPRGGGPRRPEGPDFNANFDRLGRRLRDFFSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GPGGGVRPGAIAAVVGAAFGLWALSGIYVVQPNEEAVVTTFGAYSRNEGPGLRYHLPAPI
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCCEEEECCCHH
ERVQKVPVTSLQRLDVGGAAAGAVPEESLMLTGDENIIDLQFSVTWRVADADRFVFTIRD
HHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEECCCEEEEEEEC
PEGSVKAVAESAMREVVGRTNLLDILTTGRGQVQQQAAELMQRTLDSWGAGVRIDEVQIR
CCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
SANPPQQVLAAFRDVVSAQQDQESAVNEANTYRNRVINEAKGDAARIVQAAQAYREQAVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EATGDASRFNAILNEYRRAPGATRDRIYIETMQRVLARSNKVIVDSEGASAPIILPPDVF
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCCC
RPRTQPQAPAPQAVPQTEAAQ
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PWNDNANPGPWGSPPSGDGDRRDNTPKRPRGGGPRRPEGPDFNANFDRLGRRLRDFFSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GPGGGVRPGAIAAVVGAAFGLWALSGIYVVQPNEEAVVTTFGAYSRNEGPGLRYHLPAPI
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCCEEEECCCHH
ERVQKVPVTSLQRLDVGGAAAGAVPEESLMLTGDENIIDLQFSVTWRVADADRFVFTIRD
HHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEEEEEECCCEEEEEEEC
PEGSVKAVAESAMREVVGRTNLLDILTTGRGQVQQQAAELMQRTLDSWGAGVRIDEVQIR
CCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
SANPPQQVLAAFRDVVSAQQDQESAVNEANTYRNRVINEAKGDAARIVQAAQAYREQAVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EATGDASRFNAILNEYRRAPGATRDRIYIETMQRVLARSNKVIVDSEGASAPIILPPDVF
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCCC
RPRTQPQAPAPQAVPQTEAAQ
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]