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The map label for this gene is hflC [H]

Identifier: 197104343

GI number: 197104343

Start: 970119

End: 971012

Strand: Reverse

Name: hflC [H]

Synonym: PHZ_c0877

Alternate gene names: 197104343

Gene position: 971012-970119 (Counterclockwise)

Preceding gene: 197104344

Following gene: 197104340

Centisome position: 24.3

GC content: 71.14

Gene sequence:

>894_bases
ATGAGCCGCCGTCTCTGGACCTACCTGATCGTCGGGATCGGCGCCCTCGTGGTGCTGGCCAACACCCTCTACATCGTCGA
CCAGCGCGAGCAGGCGATCGTGCTGCGCTTCGGCGACCCCGTGCGGGTCGTCAACGCGCCGGACGCGCCGGGCGCGGGCT
TGAACGCGAAGATCCCGTTCTGGGAGAACGTGATCAAGTTCGACCGGCGGAACCTGGCGCTCGAGAGCCAGCAGGAAGAG
ATCATCACCGCCGACCAGCAGCGGCTCGTCGTCGACGCCTTCGTCCGCTACCGCATCTCGGATCCGCTGGCCTTCTACCG
GACCCTGCGCGACGAGCGCACCGCCACCGACCGGATCGAGCGGCTGGTGAACTCGTCCCTGCGCCAGGTGCTGGGCTCGG
CGCCCCAGACCGAGATCATCTCGGGCGGCCGCGGCCGGCTGATGCAGCTCGCGCGCAACGACGTCGCCCGCCGGGCCGAG
GCCTCGCGCTTCGGCATCCAGGTGATTGACGTGCGGATCCGCCGGGCCGACTTCCCGGCCGGCAACCAGGAGGCCGTGTT
CCGCCGCATGCAGACCTCGCGTCAGCAGGAGGCCGCGCGCATCCGGGCCGAGGGCGAGCAGCAGAAGCGCGAGATCATCG
CCCAGGCCGACCGCGAGGTGACCATCACCCTCGCCCAGGCCCGCGAGCTGGGCGAGACCACCCGAGGCGAGGGCGACGCC
CAGCGCACCCGGATCTTCGCCCAGAGCTTCGGCCGCGACCCGTCGTTCGCCGCCTTCTGGCGCTCGATGCAGGCCTACGA
GGCGAGCCTGGCCCAGGGGGACACCACCATGGTGCTCTCGCCGGACAGCGCGTTCTTCCGCTACTTCGAGCGGGGCCCGT
CGGGCAGCCGCTAG

Upstream 100 bases:

>100_bases
GCGCCTCCGCGCCGATCATCCTGCCGCCCGACGTGTTCCGGCCCAGGACCCAGCCGCAGGCGCCCGCGCCGCAGGCCGTC
CCGCAGACGGAGGCCGCCCA

Downstream 100 bases:

>100_bases
GCCGCTTGACCCGCGAGATTACGCGCGTAACCTGACGTTGGATTACGAAAGTAATCTGACTGCTTACCGCAATCCCCTTC
CCCTCTCCGGCCCGTCCGGG

Product: protease subunit hflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSRRLWTYLIVGIGALVVLANTLYIVDQREQAIVLRFGDPVRVVNAPDAPGAGLNAKIPFWENVIKFDRRNLALESQQEE
IITADQQRLVVDAFVRYRISDPLAFYRTLRDERTATDRIERLVNSSLRQVLGSAPQTEIISGGRGRLMQLARNDVARRAE
ASRFGIQVIDVRIRRADFPAGNQEAVFRRMQTSRQQEAARIRAEGEQQKREIIAQADREVTITLAQARELGETTRGEGDA
QRTRIFAQSFGRDPSFAAFWRSMQAYEASLAQGDTTMVLSPDSAFFRYFERGPSGSR

Sequences:

>Translated_297_residues
MSRRLWTYLIVGIGALVVLANTLYIVDQREQAIVLRFGDPVRVVNAPDAPGAGLNAKIPFWENVIKFDRRNLALESQQEE
IITADQQRLVVDAFVRYRISDPLAFYRTLRDERTATDRIERLVNSSLRQVLGSAPQTEIISGGRGRLMQLARNDVARRAE
ASRFGIQVIDVRIRRADFPAGNQEAVFRRMQTSRQQEAARIRAEGEQQKREIIAQADREVTITLAQARELGETTRGEGDA
QRTRIFAQSFGRDPSFAAFWRSMQAYEASLAQGDTTMVLSPDSAFFRYFERGPSGSR
>Mature_296_residues
SRRLWTYLIVGIGALVVLANTLYIVDQREQAIVLRFGDPVRVVNAPDAPGAGLNAKIPFWENVIKFDRRNLALESQQEEI
ITADQQRLVVDAFVRYRISDPLAFYRTLRDERTATDRIERLVNSSLRQVLGSAPQTEIISGGRGRLMQLARNDVARRAEA
SRFGIQVIDVRIRRADFPAGNQEAVFRRMQTSRQQEAARIRAEGEQQKREIIAQADREVTITLAQARELGETTRGEGDAQ
RTRIFAQSFGRDPSFAAFWRSMQAYEASLAQGDTTMVLSPDSAFFRYFERGPSGSR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=316, Percent_Identity=32.5949367088608, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI193209764, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17569493, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18860517, Length=245, Percent_Identity=27.3469387755102, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33641; Mature: 33509

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRLWTYLIVGIGALVVLANTLYIVDQREQAIVLRFGDPVRVVNAPDAPGAGLNAKIPF
CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCEEEEECCCCCCCCCCCCCCH
WENVIKFDRRNLALESQQEEIITADQQRLVVDAFVRYRISDPLAFYRTLRDERTATDRIE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RLVNSSLRQVLGSAPQTEIISGGRGRLMQLARNDVARRAEASRFGIQVIDVRIRRADFPA
HHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCC
GNQEAVFRRMQTSRQQEAARIRAEGEQQKREIIAQADREVTITLAQARELGETTRGEGDA
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCHH
QRTRIFAQSFGRDPSFAAFWRSMQAYEASLAQGDTTMVLSPDSAFFRYFERGPSGSR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRRLWTYLIVGIGALVVLANTLYIVDQREQAIVLRFGDPVRVVNAPDAPGAGLNAKIPF
CCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCEEEEECCCCCCCCCCCCCCH
WENVIKFDRRNLALESQQEEIITADQQRLVVDAFVRYRISDPLAFYRTLRDERTATDRIE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RLVNSSLRQVLGSAPQTEIISGGRGRLMQLARNDVARRAEASRFGIQVIDVRIRRADFPA
HHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCC
GNQEAVFRRMQTSRQQEAARIRAEGEQQKREIIAQADREVTITLAQARELGETTRGEGDA
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCHH
QRTRIFAQSFGRDPSFAAFWRSMQAYEASLAQGDTTMVLSPDSAFFRYFERGPSGSR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]