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The map label for this gene is 197104223

Identifier: 197104223

GI number: 197104223

Start: 834131

End: 835522

Strand: Reverse

Name: 197104223

Synonym: PHZ_c0757

Alternate gene names: NA

Gene position: 835522-834131 (Counterclockwise)

Preceding gene: 197104224

Following gene: 197104221

Centisome position: 20.91

GC content: 68.46

Gene sequence:

>1392_bases
ATGGCCCAGGCGCTGCCGAAGGCGTGCATCATCGGCGCGGGCTGTTCCGGCTTCACGACCGCCAAGCGGCTGAAGGACCT
GGGCGTGCCGTTCGACTGCTTCGAGATGTCGGACGACATCGGCGGCAACTGGTACTTCAAAAACCCGAACGGCCTGTCGG
CCTGCTACGAGAGCCTGCACATCGACACGTCGAAGTGGCGCCTGGCCTTCGAGGACTATCCGGTCCCCGCCGACTGGCCC
GACTTCCCGCACCACGCCCAGCTCCTGAAGTACTTCCACGACTACGTGGACCACTTCGGCCTGCGCCCCCTGATCACCTT
CAACACCGCGGTCACCCACGCCGAGCGCACGGCGGAGGGGCTCTGGTCGGTGACGCTGTCGACCGGTGAGACTCGCCTCT
ACGACGTGCTGTTCGTCTGCAACGGCCACCACTGGGACGCGCGCATCCCGGAGTATCCCGGCGCCTTCGACGGGCCGGCC
TTCCACGCCCACGAATACCGCGACCCGTTCGACCCCGTGGACATGCGCGGCAAGAACATCGTCGTCGTCGGCATGGGCAA
TTCGGCGATGGACATCGCCTCGGAGCTGTCCCAGCGGCCGATCGCGAGGAACCTCTGGGTCGCCGCCCGGCGCGGCGTCT
GGGTGCTGCCGAAGTACATGGACGGCCGGCCGGCGGACAAGGCGGCCCTGCCCCCCTGGTTCCCGCGCAAGCTGGGCCTG
GCGCTGGCCCGCAAGAAAATCAAGCGGGCCATCGGGCGGATGGAGGACTACGGCCTGCCCAAGCCCGACCACGAGCCGCT
GGAGGCGCACCCGTCCGTCTCGGGCGAGTTCCTGACCCGGGCCGGCTGCGGCGACGTGAAGTTCAAGCCGAACATCGCCG
AGCTGATGGGCAAGAAGGTCCGCTTCGAGGACGGCAGCGTCGAGGACGTGGACGCCATCGTCTACGCCACCGGCTACAGG
ATCAGCTTCCCGTTCTTCACGGATCCCGAGCTGCTGCCGGACGCCGAGCACCGCTTCCCGCTGTTCAAGCGGATGATGAA
GCCGGGAATCCCGAACCTGTTCTTCATGGGCCTGGCCCAGCCCCTGCCGACGCTGGTCAACTTCGCCGAGCAGCAGGCCA
AGCTCGCCGGCGCCTACCTCGTGGGCCGCTACAAGCCGCCCGCGCCCGCGGAGATGGCGCAGGTCACCGCCAAGGACGAG
GCCCTGCACCTCGGCCCCTACTACAAGTCGGCCAGGCACACGATCCAGGTGGACTTCGGGATCTACGTCCACGACCTCCT
GAAGGAGATCGAGCGCGGCGGGAAGCGGGCGAAGGCCGCCGGCTACGCCCTGCCAGTTCCCGCCCGCGCGGTCAGCGCGT
CACGATCGGAAAGTCCGGCCGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GCGCGCTGGTGTGAGGCGGCGTCCCTCCCGGCAAGGGAGGGTTGCCCGCCCCCACGGAAGGCCGTGAAACTCTCCCCGAC
GACTTAGGGGAGAAACCACC

Downstream 100 bases:

>100_bases
GGAAGCCCAGCAGGCGGACGAGCGCCCCGGCTTCGCCCTCCGAGGCCGCCGGCGGCCTGGCCCCCGCCAGGGCCGCCGCC
AGGAACTGGGCCCGCGGCAG

Product: monooxygenase, flavin-binding family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MAQALPKACIIGAGCSGFTTAKRLKDLGVPFDCFEMSDDIGGNWYFKNPNGLSACYESLHIDTSKWRLAFEDYPVPADWP
DFPHHAQLLKYFHDYVDHFGLRPLITFNTAVTHAERTAEGLWSVTLSTGETRLYDVLFVCNGHHWDARIPEYPGAFDGPA
FHAHEYRDPFDPVDMRGKNIVVVGMGNSAMDIASELSQRPIARNLWVAARRGVWVLPKYMDGRPADKAALPPWFPRKLGL
ALARKKIKRAIGRMEDYGLPKPDHEPLEAHPSVSGEFLTRAGCGDVKFKPNIAELMGKKVRFEDGSVEDVDAIVYATGYR
ISFPFFTDPELLPDAEHRFPLFKRMMKPGIPNLFFMGLAQPLPTLVNFAEQQAKLAGAYLVGRYKPPAPAEMAQVTAKDE
ALHLGPYYKSARHTIQVDFGIYVHDLLKEIERGGKRAKAAGYALPVPARAVSASRSESPAAAA

Sequences:

>Translated_463_residues
MAQALPKACIIGAGCSGFTTAKRLKDLGVPFDCFEMSDDIGGNWYFKNPNGLSACYESLHIDTSKWRLAFEDYPVPADWP
DFPHHAQLLKYFHDYVDHFGLRPLITFNTAVTHAERTAEGLWSVTLSTGETRLYDVLFVCNGHHWDARIPEYPGAFDGPA
FHAHEYRDPFDPVDMRGKNIVVVGMGNSAMDIASELSQRPIARNLWVAARRGVWVLPKYMDGRPADKAALPPWFPRKLGL
ALARKKIKRAIGRMEDYGLPKPDHEPLEAHPSVSGEFLTRAGCGDVKFKPNIAELMGKKVRFEDGSVEDVDAIVYATGYR
ISFPFFTDPELLPDAEHRFPLFKRMMKPGIPNLFFMGLAQPLPTLVNFAEQQAKLAGAYLVGRYKPPAPAEMAQVTAKDE
ALHLGPYYKSARHTIQVDFGIYVHDLLKEIERGGKRAKAAGYALPVPARAVSASRSESPAAAA
>Mature_462_residues
AQALPKACIIGAGCSGFTTAKRLKDLGVPFDCFEMSDDIGGNWYFKNPNGLSACYESLHIDTSKWRLAFEDYPVPADWPD
FPHHAQLLKYFHDYVDHFGLRPLITFNTAVTHAERTAEGLWSVTLSTGETRLYDVLFVCNGHHWDARIPEYPGAFDGPAF
HAHEYRDPFDPVDMRGKNIVVVGMGNSAMDIASELSQRPIARNLWVAARRGVWVLPKYMDGRPADKAALPPWFPRKLGLA
LARKKIKRAIGRMEDYGLPKPDHEPLEAHPSVSGEFLTRAGCGDVKFKPNIAELMGKKVRFEDGSVEDVDAIVYATGYRI
SFPFFTDPELLPDAEHRFPLFKRMMKPGIPNLFFMGLAQPLPTLVNFAEQQAKLAGAYLVGRYKPPAPAEMAQVTAKDEA
LHLGPYYKSARHTIQVDFGIYVHDLLKEIERGGKRAKAAGYALPVPARAVSASRSESPAAAA

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI221316672, Length=436, Percent_Identity=35.7798165137615, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI221316674, Length=420, Percent_Identity=35.4761904761905, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4503757, Length=448, Percent_Identity=33.0357142857143, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI4503759, Length=445, Percent_Identity=28.7640449438202, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI4503755, Length=453, Percent_Identity=30.242825607064, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI50541965, Length=444, Percent_Identity=29.954954954955, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI50541961, Length=444, Percent_Identity=29.954954954955, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI221316678, Length=275, Percent_Identity=37.4545454545455, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17541300, Length=449, Percent_Identity=34.5211581291759, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI25150462, Length=454, Percent_Identity=32.8193832599119, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25145785, Length=435, Percent_Identity=29.4252873563218, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17561948, Length=448, Percent_Identity=32.8125, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17555726, Length=451, Percent_Identity=32.5942350332594, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI193202226, Length=217, Percent_Identity=32.7188940092166, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506045, Length=212, Percent_Identity=29.7169811320755, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921694, Length=216, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19922866, Length=211, Percent_Identity=27.0142180094787, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 51474; Mature: 51343

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQALPKACIIGAGCSGFTTAKRLKDLGVPFDCFEMSDDIGGNWYFKNPNGLSACYESLH
CCCCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCCEEEEECCCHHHHHHHHHC
IDTSKWRLAFEDYPVPADWPDFPHHAQLLKYFHDYVDHFGLRPLITFNTAVTHAERTAEG
CCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCC
LWSVTLSTGETRLYDVLFVCNGHHWDARIPEYPGAFDGPAFHAHEYRDPFDPVDMRGKNI
EEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VVVGMGNSAMDIASELSQRPIARNLWVAARRGVWVLPKYMDGRPADKAALPPWFPRKLGL
EEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHH
ALARKKIKRAIGRMEDYGLPKPDHEPLEAHPSVSGEFLTRAGCGDVKFKPNIAELMGKKV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEECCCHHHHCCCEE
RFEDGSVEDVDAIVYATGYRISFPFFTDPELLPDAEHRFPLFKRMMKPGIPNLFFMGLAQ
ECCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
PLPTLVNFAEQQAKLAGAYLVGRYKPPAPAEMAQVTAKDEALHLGPYYKSARHTIQVDFG
HHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCEEECCCHHHCCCEEEEEECC
IYVHDLLKEIERGGKRAKAAGYALPVPARAVSASRSESPAAAA
HHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AQALPKACIIGAGCSGFTTAKRLKDLGVPFDCFEMSDDIGGNWYFKNPNGLSACYESLH
CCCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCCEEEEECCCHHHHHHHHHC
IDTSKWRLAFEDYPVPADWPDFPHHAQLLKYFHDYVDHFGLRPLITFNTAVTHAERTAEG
CCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCC
LWSVTLSTGETRLYDVLFVCNGHHWDARIPEYPGAFDGPAFHAHEYRDPFDPVDMRGKNI
EEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VVVGMGNSAMDIASELSQRPIARNLWVAARRGVWVLPKYMDGRPADKAALPPWFPRKLGL
EEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHH
ALARKKIKRAIGRMEDYGLPKPDHEPLEAHPSVSGEFLTRAGCGDVKFKPNIAELMGKKV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEECCCHHHHCCCEE
RFEDGSVEDVDAIVYATGYRISFPFFTDPELLPDAEHRFPLFKRMMKPGIPNLFFMGLAQ
ECCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHH
PLPTLVNFAEQQAKLAGAYLVGRYKPPAPAEMAQVTAKDEALHLGPYYKSARHTIQVDFG
HHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCEEECCCHHHCCCEEEEEECC
IYVHDLLKEIERGGKRAKAAGYALPVPARAVSASRSESPAAAA
HHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]