Click here to switch to the map view.

The map label for this gene is ccrM [H]

Identifier: 197104043

GI number: 197104043

Start: 611885

End: 612964

Strand: Direct

Name: ccrM [H]

Synonym: PHZ_c0577

Alternate gene names: 197104043

Gene position: 611885-612964 (Clockwise)

Preceding gene: 197104042

Following gene: 197104045

Centisome position: 15.31

GC content: 69.26

Gene sequence:

>1080_bases
ATGGGCCTGCCGGTCGACACGATCATCGAGGGCGATTGCCTGGAGGCGCTGAAGAAGCTTCCGGACCGCTCGGTCGACCT
CGTCTTCGCAGACCCGCCCTACAACCTGCAGCTCGGCGGCGACCTCCTGCGGCCCGACAATTCCAAGGTCGACGCCGTCG
ACGATCACTGGGACCAGTTCGAGAGCTTCGAGGCCTATGACGCCTTCACCCGCGCCTGGCTGAAGGAATGCCGGCGGGTC
CTGAAGGACGACGGCGCGATCTGGGTGATCGGCAGCTACCACAACATCTTCCGCGTCGGCGTCGCGGTGCAGGACCTGGG
CTTCTGGATCCTGAACGACATCGTCTGGCGCAAGTCGAACCCGATGCCGAACTTCAAGGGCACGCGGTTCACCAACGCCC
ACGAGACCCTGATCTGGGCCTCCAAATCGCGGGGCGGCCGGCGCTACACCTTCAACTACGACGCCATGAAGATGGCCAAC
GACGAGCTGCAGATGCGCTCGGACTGGACGCTGCCGCTGTGCACCGGCGACGAGCGCCTGAAGGACGGCTCCGGCGCCAA
GGCCCACCCGACCCAGAAGCCCGAGGCCCTGCTGCACCGGGTGATCCTGGCCTCGACCAAGCCCGGCGACGTGATCCTCG
ATCCCTTCTTCGGCACCGGCACCACGGGCGCGGTGGCCAGGCGCCTGGGCCGCAAGTTCGTGGGCATCGAGCGCGAGGCC
GAGTACGCCGCCCTCGCCCGCAAGCGCATCGCCCAGGTGACGCCGGCCACGGCGGACGAGATGGCGGTGACCGGCTCCAA
GCGCGCCGAGCCGCGCGTGCCCTTCGGCACCATCCTCGAGGCCGGGCTGCTGCGGCCGGGCGACGTCCTCTACTGTCCGA
AGGGGCGCAACGCCGCCCGCGTGCGGGCGGACGGCAGCCTGGTGGTGGGCGAGGTGTCCGGCTCGATCCACAAGGTGGGC
GCGCTCGTGCAGTCGGCGCCGGCCTGCAACGGCTGGACCTACTGGCACTTCAAGTCGGACAAGGGCCTCGCCCCCATCGA
TGTGCTGCGCGCCAAGGTCCGCTCGCAGCTCCCCGCCTAG

Upstream 100 bases:

>100_bases
GCCGTTCGGCGAGGCTTAACTTCTCGTTGACCATCCGCGTCAACGGCCTCTTCACCATAAGCCCCGAGGATTCAGACTCT
GGTTCTCTTGGGGTTTGAGC

Downstream 100 bases:

>100_bases
AGCAGGTTCGAGAGCCCCGCGCGGGCCGCCTTCAGGAACACGCTGGGCAGCGCCTCCAGGTCGCCGCGCGGGCTCCAGAT
CACGCCGTCGGCGTCGCCCT

Product: modification methylase

Products: NA

Alternate protein names: M.CcrMI; Adenine-specific methyltransferase CcrMI [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MGLPVDTIIEGDCLEALKKLPDRSVDLVFADPPYNLQLGGDLLRPDNSKVDAVDDHWDQFESFEAYDAFTRAWLKECRRV
LKDDGAIWVIGSYHNIFRVGVAVQDLGFWILNDIVWRKSNPMPNFKGTRFTNAHETLIWASKSRGGRRYTFNYDAMKMAN
DELQMRSDWTLPLCTGDERLKDGSGAKAHPTQKPEALLHRVILASTKPGDVILDPFFGTGTTGAVARRLGRKFVGIEREA
EYAALARKRIAQVTPATADEMAVTGSKRAEPRVPFGTILEAGLLRPGDVLYCPKGRNAARVRADGSLVVGEVSGSIHKVG
ALVQSAPACNGWTYWHFKSDKGLAPIDVLRAKVRSQLPA

Sequences:

>Translated_359_residues
MGLPVDTIIEGDCLEALKKLPDRSVDLVFADPPYNLQLGGDLLRPDNSKVDAVDDHWDQFESFEAYDAFTRAWLKECRRV
LKDDGAIWVIGSYHNIFRVGVAVQDLGFWILNDIVWRKSNPMPNFKGTRFTNAHETLIWASKSRGGRRYTFNYDAMKMAN
DELQMRSDWTLPLCTGDERLKDGSGAKAHPTQKPEALLHRVILASTKPGDVILDPFFGTGTTGAVARRLGRKFVGIEREA
EYAALARKRIAQVTPATADEMAVTGSKRAEPRVPFGTILEAGLLRPGDVLYCPKGRNAARVRADGSLVVGEVSGSIHKVG
ALVQSAPACNGWTYWHFKSDKGLAPIDVLRAKVRSQLPA
>Mature_358_residues
GLPVDTIIEGDCLEALKKLPDRSVDLVFADPPYNLQLGGDLLRPDNSKVDAVDDHWDQFESFEAYDAFTRAWLKECRRVL
KDDGAIWVIGSYHNIFRVGVAVQDLGFWILNDIVWRKSNPMPNFKGTRFTNAHETLIWASKSRGGRRYTFNYDAMKMAND
ELQMRSDWTLPLCTGDERLKDGSGAKAHPTQKPEALLHRVILASTKPGDVILDPFFGTGTTGAVARRLGRKFVGIEREAE
YAALARKRIAQVTPATADEMAVTGSKRAEPRVPFGTILEAGLLRPGDVLYCPKGRNAARVRADGSLVVGEVSGSIHKVGA
LVQSAPACNGWTYWHFKSDKGLAPIDVLRAKVRSQLPA

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=293, Percent_Identity=33.7883959044369, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 39706; Mature: 39575

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPVDTIIEGDCLEALKKLPDRSVDLVFADPPYNLQLGGDLLRPDNSKVDAVDDHWDQF
CCCCHHHEECCHHHHHHHHCCCCCEEEEECCCCCCEEECCCEECCCCCCCCCCHHHHHHH
ESFEAYDAFTRAWLKECRRVLKDDGAIWVIGSYHNIFRVGVAVQDLGFWILNDIVWRKSN
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PMPNFKGTRFTNAHETLIWASKSRGGRRYTFNYDAMKMANDELQMRSDWTLPLCTGDERL
CCCCCCCCEECCCCEEEEEEECCCCCEEEEEECHHHHHCCCHHHHCCCCCEEEECCHHHH
KDGSGAKAHPTQKPEALLHRVILASTKPGDVILDPFFGTGTTGAVARRLGRKFVGIEREA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
EYAALARKRIAQVTPATADEMAVTGSKRAEPRVPFGTILEAGLLRPGDVLYCPKGRNAAR
HHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCEE
VRADGSLVVGEVSGSIHKVGALVQSAPACNGWTYWHFKSDKGLAPIDVLRAKVRSQLPA
EECCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLPVDTIIEGDCLEALKKLPDRSVDLVFADPPYNLQLGGDLLRPDNSKVDAVDDHWDQF
CCCHHHEECCHHHHHHHHCCCCCEEEEECCCCCCEEECCCEECCCCCCCCCCHHHHHHH
ESFEAYDAFTRAWLKECRRVLKDDGAIWVIGSYHNIFRVGVAVQDLGFWILNDIVWRKSN
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PMPNFKGTRFTNAHETLIWASKSRGGRRYTFNYDAMKMANDELQMRSDWTLPLCTGDERL
CCCCCCCCEECCCCEEEEEEECCCCCEEEEEECHHHHHCCCHHHHCCCCCEEEECCHHHH
KDGSGAKAHPTQKPEALLHRVILASTKPGDVILDPFFGTGTTGAVARRLGRKFVGIEREA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
EYAALARKRIAQVTPATADEMAVTGSKRAEPRVPFGTILEAGLLRPGDVLYCPKGRNAAR
HHHHHHHHHHHHCCCCCCHHEEECCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCEE
VRADGSLVVGEVSGSIHKVGALVQSAPACNGWTYWHFKSDKGLAPIDVLRAKVRSQLPA
EECCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8289276 [H]