Click here to switch to the map view.

The map label for this gene is fadE25 [H]

Identifier: 197104024

GI number: 197104024

Start: 590316

End: 592064

Strand: Reverse

Name: fadE25 [H]

Synonym: PHZ_c0558

Alternate gene names: 197104024

Gene position: 592064-590316 (Counterclockwise)

Preceding gene: 197104033

Following gene: 197104023

Centisome position: 14.82

GC content: 72.16

Gene sequence:

>1749_bases
ATGACCTTCCGAGCCCCCGTCCGCGACATCGCCTTCGCCCTCAAGACCGTCGGCCACTCGGCGCTGGTGGAACGCGCCTT
CCCCGACCTCGACGAGGACACCGTCCAGGCCGTGCTCGAGGCCGCCGGCGCCTTCGCCGACAACGAGCTCGCGCCGCTGA
ACCGCCGCGGCGACCTGGAAGGCGCCCGTTACGAGAACGGCAAGGTCACCGCCGCGCCGGGCTTCGCCGCCGCCTACAAG
GCCTTCGCCGAGCAGGGATGGAATTCCCTCACCGCCGATCCGCTGTTCGGCGGCCAGGGCCTGCCCAAGGCGATGGAGCT
CGCCGTCTTCGAGATGGCGCACGCCGCCAACATGGCGTTCGCGCTCTGCCCCATGCTGACCCAGGCGGCGATCGAGGCCC
TGACGCTGCACGGGACCGAGCGCCAGAAGCGCCTCGTGCTTCCCAAGCTCGTTTCCGGCGAGTGGACCGGCGCCATGGTG
CTGACCGAACCGCAGGCCGGTTCGGACCTGGCCGCGCTGACCACCCGCGCCGAGCCCGACGGCGAAGGCGGCTACCGCCT
GCACGGCCAGAAGATCTTCATCACCTGGGGCGACCACGACGCCACCGACAACATCATCCACCTGGTGCTGGCCCGCACGC
CCGACGCGCCTCCGGGCGTCAAGGGCATCAGCCTCTTCCTGACCTCGAAGTACGAGCTGAAGGACGACGGCTCGCTGGGG
TCGCGCAACGACTTCCGCCCCGGCTCCATCGAGCACAAGCTGGGCATCCACGCCTCGCCGACCTGCGTCATGCTCTACGA
GGGCGCCAAGGCCGAGCTGGTCGGCGAACTGGGCCAGGGCCTGGCCCACATGTTCGTCATGATGAACGCCGCCCGGGTCC
AGGTGGGCGTACAGGGGGTCGGCATCGCCGAGCGCGCCTTCCAGCAGGCGCTGGCCTTCGCCCAGGAGCGCCGGCAGGGC
CGCGCCGTCTGGTCGGCCGACTATCCGGCGGCGATCTACGACCATCCCGACGTGCGCCGCACGCTGATGCTGATGAAGGC
CAAGATCGAGGCGGCCCGGGGCATCTGCCTGACCACCGGCGTCCTGGCCGATCTCGCGCACCGCGCCGAGGACGAGGACG
AGCGCGCCGCCGCCAAGGCGCGGCAGGAGCTGCTGACGCCGATCGCCAAGGCCTGGTCCACCGACGTCGGGGTCGAGGTC
GCCTCGGCCGGCGTGCAGATCCATGGCGGCATGGGCTTCATCGAGGAGACCGGCGCGGCCCAGCACTACCGCGACGCCCG
CATCGCCCCGATCTACGAAGGCACCAACGGCATCCAGGCCGCCGACCTCGTGGGCCGGAAGGTGCGGATGAACGGCGGCG
AGACCATGCGCGGCCTCTGCGCCGAGATGATGCTCTCGGCCCAGGCGCTGGCCGACAGTCCCGGCCTCGCCCCGGTGGGC
CGCCGGCTCGCCGAGGGCGTGGCGGCGCTGGAGCGCGCCACCGACTGGCTGCTCGGCGCGGACAACGGCGCGGCCCTGGC
CGCCTCCGTTCCCTATCTGAAGCTCGCCGGGGATGTGGTGGGCGGCTGGATCCTCGGCCGACTGGCGATCGCCGCCGACG
GTTCGGACGAGCCCTGGCTGCAGGCCAAGGGCGCGCTGGCCCGCCTCTACGCCGCCCAGGTGCTCAGCACCGCGCCCGGC
GCCGCTGACGGCTTGGGCGAAGGCTGGGACGAGCTCGAACAGACCCCCGCCGCACTCCTCGCTGGGTAG

Upstream 100 bases:

>100_bases
CGCCGTATGGGGATCGGTCGGGTCCACCCGCGGCCGTTACACGAGGGGTGACCCATGCGGCAACTTTCCCGGCTCGCGCC
GTGCGTCTAGAACCCCGGCC

Downstream 100 bases:

>100_bases
AGCCGGCTCCACCATCGGTGGAATAGCATTGTTTTTCTAAGCTTTACCTTTTTCGCGTAAGTCTTTCCGCCGGGAGACAA
GGGCGTCATGTCTGACGGGG

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MTFRAPVRDIAFALKTVGHSALVERAFPDLDEDTVQAVLEAAGAFADNELAPLNRRGDLEGARYENGKVTAAPGFAAAYK
AFAEQGWNSLTADPLFGGQGLPKAMELAVFEMAHAANMAFALCPMLTQAAIEALTLHGTERQKRLVLPKLVSGEWTGAMV
LTEPQAGSDLAALTTRAEPDGEGGYRLHGQKIFITWGDHDATDNIIHLVLARTPDAPPGVKGISLFLTSKYELKDDGSLG
SRNDFRPGSIEHKLGIHASPTCVMLYEGAKAELVGELGQGLAHMFVMMNAARVQVGVQGVGIAERAFQQALAFAQERRQG
RAVWSADYPAAIYDHPDVRRTLMLMKAKIEAARGICLTTGVLADLAHRAEDEDERAAAKARQELLTPIAKAWSTDVGVEV
ASAGVQIHGGMGFIEETGAAQHYRDARIAPIYEGTNGIQAADLVGRKVRMNGGETMRGLCAEMMLSAQALADSPGLAPVG
RRLAEGVAALERATDWLLGADNGAALAASVPYLKLAGDVVGGWILGRLAIAADGSDEPWLQAKGALARLYAAQVLSTAPG
AADGLGEGWDELEQTPAALLAG

Sequences:

>Translated_582_residues
MTFRAPVRDIAFALKTVGHSALVERAFPDLDEDTVQAVLEAAGAFADNELAPLNRRGDLEGARYENGKVTAAPGFAAAYK
AFAEQGWNSLTADPLFGGQGLPKAMELAVFEMAHAANMAFALCPMLTQAAIEALTLHGTERQKRLVLPKLVSGEWTGAMV
LTEPQAGSDLAALTTRAEPDGEGGYRLHGQKIFITWGDHDATDNIIHLVLARTPDAPPGVKGISLFLTSKYELKDDGSLG
SRNDFRPGSIEHKLGIHASPTCVMLYEGAKAELVGELGQGLAHMFVMMNAARVQVGVQGVGIAERAFQQALAFAQERRQG
RAVWSADYPAAIYDHPDVRRTLMLMKAKIEAARGICLTTGVLADLAHRAEDEDERAAAKARQELLTPIAKAWSTDVGVEV
ASAGVQIHGGMGFIEETGAAQHYRDARIAPIYEGTNGIQAADLVGRKVRMNGGETMRGLCAEMMLSAQALADSPGLAPVG
RRLAEGVAALERATDWLLGADNGAALAASVPYLKLAGDVVGGWILGRLAIAADGSDEPWLQAKGALARLYAAQVLSTAPG
AADGLGEGWDELEQTPAALLAG
>Mature_581_residues
TFRAPVRDIAFALKTVGHSALVERAFPDLDEDTVQAVLEAAGAFADNELAPLNRRGDLEGARYENGKVTAAPGFAAAYKA
FAEQGWNSLTADPLFGGQGLPKAMELAVFEMAHAANMAFALCPMLTQAAIEALTLHGTERQKRLVLPKLVSGEWTGAMVL
TEPQAGSDLAALTTRAEPDGEGGYRLHGQKIFITWGDHDATDNIIHLVLARTPDAPPGVKGISLFLTSKYELKDDGSLGS
RNDFRPGSIEHKLGIHASPTCVMLYEGAKAELVGELGQGLAHMFVMMNAARVQVGVQGVGIAERAFQQALAFAQERRQGR
AVWSADYPAAIYDHPDVRRTLMLMKAKIEAARGICLTTGVLADLAHRAEDEDERAAAKARQELLTPIAKAWSTDVGVEVA
SAGVQIHGGMGFIEETGAAQHYRDARIAPIYEGTNGIQAADLVGRKVRMNGGETMRGLCAEMMLSAQALADSPGLAPVGR
RLAEGVAALERATDWLLGADNGAALAASVPYLKLAGDVVGGWILGRLAIAADGSDEPWLQAKGALARLYAAQVLSTAPGA
ADGLGEGWDELEQTPAALLAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=411, Percent_Identity=27.4939172749392, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI4501857, Length=320, Percent_Identity=28.125, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4557233, Length=422, Percent_Identity=27.2511848341232, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=27.2020725388601, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4557235, Length=386, Percent_Identity=27.2020725388601, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI21361497, Length=405, Percent_Identity=26.6666666666667, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=27.5482093663912, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI226958412, Length=438, Percent_Identity=25.3424657534247, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226958414, Length=373, Percent_Identity=26.0053619302949, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI187960098, Length=316, Percent_Identity=28.7974683544304, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4557231, Length=316, Percent_Identity=28.7974683544304, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI87082384, Length=349, Percent_Identity=28.080229226361, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=26.525198938992, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=471, Percent_Identity=27.1762208067941, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI86563381, Length=471, Percent_Identity=27.1762208067941, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17508101, Length=305, Percent_Identity=31.1475409836066, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17533517, Length=408, Percent_Identity=26.7156862745098, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=349, Percent_Identity=28.6532951289398, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71990804, Length=219, Percent_Identity=31.9634703196347, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=371, Percent_Identity=26.9541778975741, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=424, Percent_Identity=25.7075471698113, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=349, Percent_Identity=27.2206303724928, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=323, Percent_Identity=28.1733746130031, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=365, Percent_Identity=26.8493150684932, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=302, Percent_Identity=30.794701986755, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=29.6943231441048, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=366, Percent_Identity=24.5901639344262, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=25.3048780487805, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534353, Length=335, Percent_Identity=25.9701492537313, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666513, Length=421, Percent_Identity=27.0783847980998, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21355753, Length=439, Percent_Identity=27.7904328018223, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356377, Length=421, Percent_Identity=26.8408551068884, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646207, Length=429, Percent_Identity=26.3403263403263, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24660351, Length=350, Percent_Identity=30.8571428571429, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363737, Length=316, Percent_Identity=26.2658227848101, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920834, Length=332, Percent_Identity=27.1084337349398, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 61470; Mature: 61338

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRAPVRDIAFALKTVGHSALVERAFPDLDEDTVQAVLEAAGAFADNELAPLNRRGDLE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GARYENGKVTAAPGFAAAYKAFAEQGWNSLTADPLFGGQGLPKAMELAVFEMAHAANMAF
CCEECCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALCPMLTQAAIEALTLHGTERQKRLVLPKLVSGEWTGAMVLTEPQAGSDLAALTTRAEPD
HHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHCCCCCCEEEEECCCCCCCHHHEEECCCCC
GEGGYRLHGQKIFITWGDHDATDNIIHLVLARTPDAPPGVKGISLFLTSKYELKDDGSLG
CCCCEEEECCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECEEECCCCCCC
SRNDFRPGSIEHKLGIHASPTCVMLYEGAKAELVGELGQGLAHMFVMMNAARVQVGVQGV
CCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
GIAERAFQQALAFAQERRQGRAVWSADYPAAIYDHPDVRRTLMLMKAKIEAARGICLTTG
CHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHHH
VLADLAHRAEDEDERAAAKARQELLTPIAKAWSTDVGVEVASAGVQIHGGMGFIEETGAA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCHHHCCCH
QHYRDARIAPIYEGTNGIQAADLVGRKVRMNGGETMRGLCAEMMLSAQALADSPGLAPVG
HHHCCCCCEEEEECCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
RRLAEGVAALERATDWLLGADNGAALAASVPYLKLAGDVVGGWILGRLAIAADGSDEPWL
HHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCCHH
QAKGALARLYAAQVLSTAPGAADGLGEGWDELEQTPAALLAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHCC
>Mature Secondary Structure 
TFRAPVRDIAFALKTVGHSALVERAFPDLDEDTVQAVLEAAGAFADNELAPLNRRGDLE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GARYENGKVTAAPGFAAAYKAFAEQGWNSLTADPLFGGQGLPKAMELAVFEMAHAANMAF
CCEECCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALCPMLTQAAIEALTLHGTERQKRLVLPKLVSGEWTGAMVLTEPQAGSDLAALTTRAEPD
HHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHCCCCCCEEEEECCCCCCCHHHEEECCCCC
GEGGYRLHGQKIFITWGDHDATDNIIHLVLARTPDAPPGVKGISLFLTSKYELKDDGSLG
CCCCEEEECCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECEEECCCCCCC
SRNDFRPGSIEHKLGIHASPTCVMLYEGAKAELVGELGQGLAHMFVMMNAARVQVGVQGV
CCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
GIAERAFQQALAFAQERRQGRAVWSADYPAAIYDHPDVRRTLMLMKAKIEAARGICLTTG
CHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCHHHHH
VLADLAHRAEDEDERAAAKARQELLTPIAKAWSTDVGVEVASAGVQIHGGMGFIEETGAA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCHHHCCCH
QHYRDARIAPIYEGTNGIQAADLVGRKVRMNGGETMRGLCAEMMLSAQALADSPGLAPVG
HHHCCCCCEEEEECCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
RRLAEGVAALERATDWLLGADNGAALAASVPYLKLAGDVVGGWILGRLAIAADGSDEPWL
HHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHEEEEECCCCCCHH
QAKGALARLYAAQVLSTAPGAADGLGEGWDELEQTPAALLAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]