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The map label for this gene is ctaD [H]

Identifier: 197104009

GI number: 197104009

Start: 574385

End: 576034

Strand: Direct

Name: ctaD [H]

Synonym: PHZ_c0543

Alternate gene names: 197104009

Gene position: 574385-576034 (Clockwise)

Preceding gene: 197104008

Following gene: 197104010

Centisome position: 14.37

GC content: 65.33

Gene sequence:

>1650_bases
ATGGCACACGCCGCCGCTCACGATCACGGTCACGATCACAAGCCGCCCTTCATCACGCGTTGGTTCTTCTCGACCAACCA
CAAGGACATCGGCACCCTCTACATCCTGTTCGCCATCATGGCGGGCCTGATCGGGGGCGCCCTGTCCGGCCTGATCCGCT
GGGAACTGGCCGAGCCGGGCATCCAGGTGTTCCGCGAAGGCGGGCTGCTGAGCCAGCTCGGGCTCATCGATCCGACCAAG
CACGGCTACAACGTCGTGGTCACCGCCCACGCCCTGATCATGGTGTTCTTCGTCGTCATGCCGGCGACGATGGGCGGGTT
CGGCAACTGGTTCGTGCCGCTGATGATCGGCGCGCCGGACATGGCCTTCCCGCGGATGAACAACATCTCGTTCTGGCTGC
TGTTCGCCGCCTTCATGCTGCTGTGCGTGTCCCTGTTCGTCGACGGCGGCCCGGGCCGCGGCTTCGGCGGCGGCTGGACG
GCCTATCCGCCGCTGTCCACCTCGGGCCACACCGGCCCCTCGATGGACCTGGCGATCCTGTCGCTCCACCTCGCGGGCGC
CAGCTCGATCCTGGGTTCGATCAACTTCATCACGACGATCTTCAACATGCGCGCGCCGGGCATGACCCTGCACCGCATGC
CGCTGTTCGCGTGGGGCGTGCTGATCACCGCCTTCCTGCTGCTGCTGTCGCTGCCGGTCCTGGCGGGCGCGATCACGATG
CTGCTCACCGACCGCAACTTCAACACGCACTTCTTCGACGCGGCCGGCGGCGGCGACCCGGTGATGTACCAGCACCTGTT
CTGGTTCTTCGGGCACCCCGAGGTCTACATCATGATCCTGCCGGGCTTCGGGATCATCAGCCACATCGTCTCGACGTTCT
CGCGCAAGCCGATCTTCGGTTACCTGGCGATGGCCTACGCCATGGTCGCCATCGGCTTCATCGGCTTCATCGTGTGGGCG
CACCACATGTACACGGTGGGCATGCCCATCAACCTGCGCGCCTACTTCGTGGCCGCGACGATGGTCATCGCCGTTCCGAC
GGGCGTGAAGGTGTTCAGCTGGATCGCCACGATGTGGGGCGGCTCGATCGAGTTCAAGACGCCCATGCTGTGGGCGATCG
GCTTCATCTTCCTGTTCACGGTGGGCGGCGTCACGGGCGTCGTGCTGGCCAACGCCGGCATCGACTACAGCCTGCACGAC
ACCTACTACGTGGTGGCCCACTTCCACTACGTGCTCAGCCTGGGCGCCGTGTTCTCGATCTTCGCCGGCTTCTACTACTG
GTTCGAGAAGATGTGGGGCGTGAAGTACCGCGAGTGGCTGGGCGCCCTGCACTTCTGGGTCACCTTCATCGGCGTGAACC
TGATCTTCTTCCCGCAGCACTTCCTGGGCCTGCAGGGCATGCCCCGGCGCTACGTGGACTATCCCGAGGCGTTCACCTTC
TGGAACCAGGTGTCCTCGCTGGGCTACGTGGTGACCCTGGTGGGCGTGGGGATCTTCCTGGTGGTCCTGCTCGACGCGAT
GGTCTTCCGCCGCAAGGCCGAGGCCAATCCGTGGGGCGAGGGCGCGACGACGCTGGAGTGGACCCTCCCGTCGCCGCCGC
CGTTCCACCAGTTCAACGAACTGCCGGTGGTCAAGCCGGACGCCCACTAG

Upstream 100 bases:

>100_bases
CCGCCGCCGACGCGGCCCAGCCGGCCGCCGCCGAGCCCGCCGCCACCACTCAGCCTGCGCCTGTGGCGCCGGCCGCGAAA
TAAGCCAGGACTAGAGTAAG

Downstream 100 bases:

>100_bases
CGTCAGGCTCCTCCGGGACCATCTATGAGGGGCGCGCTCCGACGGGGCGCGCCCCTCGGACATTGTAGAGTATATGCTCA
TGGCCATGTCGCCGGCCCTC

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MAHAAAHDHGHDHKPPFITRWFFSTNHKDIGTLYILFAIMAGLIGGALSGLIRWELAEPGIQVFREGGLLSQLGLIDPTK
HGYNVVVTAHALIMVFFVVMPATMGGFGNWFVPLMIGAPDMAFPRMNNISFWLLFAAFMLLCVSLFVDGGPGRGFGGGWT
AYPPLSTSGHTGPSMDLAILSLHLAGASSILGSINFITTIFNMRAPGMTLHRMPLFAWGVLITAFLLLLSLPVLAGAITM
LLTDRNFNTHFFDAAGGGDPVMYQHLFWFFGHPEVYIMILPGFGIISHIVSTFSRKPIFGYLAMAYAMVAIGFIGFIVWA
HHMYTVGMPINLRAYFVAATMVIAVPTGVKVFSWIATMWGGSIEFKTPMLWAIGFIFLFTVGGVTGVVLANAGIDYSLHD
TYYVVAHFHYVLSLGAVFSIFAGFYYWFEKMWGVKYREWLGALHFWVTFIGVNLIFFPQHFLGLQGMPRRYVDYPEAFTF
WNQVSSLGYVVTLVGVGIFLVVLLDAMVFRRKAEANPWGEGATTLEWTLPSPPPFHQFNELPVVKPDAH

Sequences:

>Translated_549_residues
MAHAAAHDHGHDHKPPFITRWFFSTNHKDIGTLYILFAIMAGLIGGALSGLIRWELAEPGIQVFREGGLLSQLGLIDPTK
HGYNVVVTAHALIMVFFVVMPATMGGFGNWFVPLMIGAPDMAFPRMNNISFWLLFAAFMLLCVSLFVDGGPGRGFGGGWT
AYPPLSTSGHTGPSMDLAILSLHLAGASSILGSINFITTIFNMRAPGMTLHRMPLFAWGVLITAFLLLLSLPVLAGAITM
LLTDRNFNTHFFDAAGGGDPVMYQHLFWFFGHPEVYIMILPGFGIISHIVSTFSRKPIFGYLAMAYAMVAIGFIGFIVWA
HHMYTVGMPINLRAYFVAATMVIAVPTGVKVFSWIATMWGGSIEFKTPMLWAIGFIFLFTVGGVTGVVLANAGIDYSLHD
TYYVVAHFHYVLSLGAVFSIFAGFYYWFEKMWGVKYREWLGALHFWVTFIGVNLIFFPQHFLGLQGMPRRYVDYPEAFTF
WNQVSSLGYVVTLVGVGIFLVVLLDAMVFRRKAEANPWGEGATTLEWTLPSPPPFHQFNELPVVKPDAH
>Mature_548_residues
AHAAAHDHGHDHKPPFITRWFFSTNHKDIGTLYILFAIMAGLIGGALSGLIRWELAEPGIQVFREGGLLSQLGLIDPTKH
GYNVVVTAHALIMVFFVVMPATMGGFGNWFVPLMIGAPDMAFPRMNNISFWLLFAAFMLLCVSLFVDGGPGRGFGGGWTA
YPPLSTSGHTGPSMDLAILSLHLAGASSILGSINFITTIFNMRAPGMTLHRMPLFAWGVLITAFLLLLSLPVLAGAITML
LTDRNFNTHFFDAAGGGDPVMYQHLFWFFGHPEVYIMILPGFGIISHIVSTFSRKPIFGYLAMAYAMVAIGFIGFIVWAH
HMYTVGMPINLRAYFVAATMVIAVPTGVKVFSWIATMWGGSIEFKTPMLWAIGFIFLFTVGGVTGVVLANAGIDYSLHDT
YYVVAHFHYVLSLGAVFSIFAGFYYWFEKMWGVKYREWLGALHFWVTFIGVNLIFFPQHFLGLQGMPRRYVDYPEAFTFW
NQVSSLGYVVTLVGVGIFLVVLLDAMVFRRKAEANPWGEGATTLEWTLPSPPPFHQFNELPVVKPDAH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=526, Percent_Identity=61.0266159695818, Blast_Score=589, Evalue=1e-168,
Organism=Escherichia coli, GI1786634, Length=529, Percent_Identity=42.34404536862, Blast_Score=380, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226519, Length=549, Percent_Identity=54.2805100182149, Blast_Score=587, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6226524, Length=339, Percent_Identity=58.7020648967552, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6226523, Length=264, Percent_Identity=53.030303030303, Blast_Score=250, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60830; Mature: 60699

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAAAHDHGHDHKPPFITRWFFSTNHKDIGTLYILFAIMAGLIGGALSGLIRWELAEPG
CCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IQVFREGGLLSQLGLIDPTKHGYNVVVTAHALIMVFFVVMPATMGGFGNWFVPLMIGAPD
HHHHHCCCCHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
MAFPRMNNISFWLLFAAFMLLCVSLFVDGGPGRGFGGGWTAYPPLSTSGHTGPSMDLAIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
SLHLAGASSILGSINFITTIFNMRAPGMTLHRMPLFAWGVLITAFLLLLSLPVLAGAITM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTDRNFNTHFFDAAGGGDPVMYQHLFWFFGHPEVYIMILPGFGIISHIVSTFSRKPIFG
HEECCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCHHH
YLAMAYAMVAIGFIGFIVWAHHMYTVGMPINLRAYFVAATMVIAVPTGVKVFSWIATMWG
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GSIEFKTPMLWAIGFIFLFTVGGVTGVVLANAGIDYSLHDTYYVVAHFHYVLSLGAVFSI
CCEEECCHHHHHHHHHHHHHHHCHHEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH
FAGFYYWFEKMWGVKYREWLGALHFWVTFIGVNLIFFPQHFLGLQGMPRRYVDYPEAFTF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHCCCCHHHHH
WNQVSSLGYVVTLVGVGIFLVVLLDAMVFRRKAEANPWGEGATTLEWTLPSPPPFHQFNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
LPVVKPDAH
CCCCCCCCC
>Mature Secondary Structure 
AHAAAHDHGHDHKPPFITRWFFSTNHKDIGTLYILFAIMAGLIGGALSGLIRWELAEPG
CCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IQVFREGGLLSQLGLIDPTKHGYNVVVTAHALIMVFFVVMPATMGGFGNWFVPLMIGAPD
HHHHHCCCCHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
MAFPRMNNISFWLLFAAFMLLCVSLFVDGGPGRGFGGGWTAYPPLSTSGHTGPSMDLAIL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
SLHLAGASSILGSINFITTIFNMRAPGMTLHRMPLFAWGVLITAFLLLLSLPVLAGAITM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTDRNFNTHFFDAAGGGDPVMYQHLFWFFGHPEVYIMILPGFGIISHIVSTFSRKPIFG
HEECCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCHHH
YLAMAYAMVAIGFIGFIVWAHHMYTVGMPINLRAYFVAATMVIAVPTGVKVFSWIATMWG
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GSIEFKTPMLWAIGFIFLFTVGGVTGVVLANAGIDYSLHDTYYVVAHFHYVLSLGAVFSI
CCEEECCHHHHHHHHHHHHHHHCHHEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH
FAGFYYWFEKMWGVKYREWLGALHFWVTFIGVNLIFFPQHFLGLQGMPRRYVDYPEAFTF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHCCCCHHHHH
WNQVSSLGYVVTLVGVGIFLVVLLDAMVFRRKAEANPWGEGATTLEWTLPSPPPFHQFNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
LPVVKPDAH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]