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The map label for this gene is hutI [H]

Identifier: 197103931

GI number: 197103931

Start: 480805

End: 481986

Strand: Direct

Name: hutI [H]

Synonym: PHZ_c0465

Alternate gene names: 197103931

Gene position: 480805-481986 (Clockwise)

Preceding gene: 197103928

Following gene: 197103932

Centisome position: 12.03

GC content: 74.11

Gene sequence:

>1182_bases
ATGAGGGTCTGGCGGAACGCCCGGCTGGCGACGCTCGATCCGCGCCTGCCGGGCCTGGGGATCGTGGAGGACGGCGCCGT
CGCGGCCGACGGCGAGCGGATCGTCTATGTCGGCCCGGCCGCCGACGCGCCGGACGGCGAGACGGTCGACTGCGAAGGCC
GCTGGATCACGCCGGGCCTCATCGACTGCCACACCCACCTCGTCTACGCGGGCGACCGGGCGCACGAGTTCGAGCTGAGG
CTGGCCGGCGCCACCTACGAGGAGATCGCCAGGGCCGGCGGCGGCATCGCCTCGACCGTCGCCGCGACCCGGGCCGCGAC
GGAAGCCGAGCTGACGGCGGCGGCGCGGCCGCGCCTGGAGTCCCTGGTCGCCGAGGGCGTGACGACGGTCGAGATCAAGT
CCGGCTACGGCCTCTCGACGGCCGGGGAGCTCAAGCAGCTGCGCGCGGCGCGGGCGCTCGGAGATGCGGCCACGATCGTC
ACCAGCTTCCTGGGCGCGCACGCGGTTCCCAGCGAGTACGCGGGCGATCCCGACGCCTACATCGACCTGGTCTGCGAGGA
GATGATCCCTGCCGTGGCGGCCGAGGGCCTCGCCGACGCCGTGGACGCCTTCTGCGAGGGGATCGGCTTCGCCCCGGCCC
AGACCGAGCGGGTTTTCCAGGCGGCCAAGCGCCACGGCCTGCCGGTGAAGCTGCACGCCGAACAGCTGTCGAACCTCAAC
GGGGCGGCGCTGGCGGCGCGCTACGGGGCGATCTCGGCCGACCACCTGGAGCACCTGGACGAGGCCGGCGTCGCCGCCAT
GGCCAAGGCCGGGACCGCCGCCGTGCTGCTGCCGGGGGCGTTCTACTTCCTGCGCGACGAACGGCTGCCGCCGATCGGCC
TGCTGCGCGCCGCCGCCGTGCCGATGGCGGTGGCCACCGACTGCAACCCCGGCACCTCGCCGCTGACCTCGCTGCTGCTG
GCGATGAACATGGCCGCGACCCTGTTCCGGCTGACGGTCGACGAGTGCCTGGCCGGCGTCACCCGCAACGCCGCCCGCGC
GCTGGGCCTGCAGGACAGCCTCGGCGTGCTGGCGGCGGGCAAGCGCTGCGATCTCGCCATCTGGGACGTCGAGCGGCCCG
CCGAGCTCGTCTACCGCATGGGATTCAATCCGCTGCACGCCCGCGTCTGGAGGGGCCGTTGA

Upstream 100 bases:

>100_bases
TTCAAACCACAGCGAGCGGGCCTTCGCGATCACTGGACACCCTTCCTGCCTTGGCCATAATGTCTATACATATTCGCGGC
CGCAGGCGAGAGGGAGGACG

Downstream 100 bases:

>100_bases
CCGACATCGTCCTGGAGCCCGGCGCTGCGCCGCTGTCCGTCTGGCGCGAGATCTGGCGCGGGGCGGGGGTGCGCCTCGAT
CCCGCCGCCCACGCCGTGGT

Product: imidazolone-5-propionate hydrolase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MRVWRNARLATLDPRLPGLGIVEDGAVAADGERIVYVGPAADAPDGETVDCEGRWITPGLIDCHTHLVYAGDRAHEFELR
LAGATYEEIARAGGGIASTVAATRAATEAELTAAARPRLESLVAEGVTTVEIKSGYGLSTAGELKQLRAARALGDAATIV
TSFLGAHAVPSEYAGDPDAYIDLVCEEMIPAVAAEGLADAVDAFCEGIGFAPAQTERVFQAAKRHGLPVKLHAEQLSNLN
GAALAARYGAISADHLEHLDEAGVAAMAKAGTAAVLLPGAFYFLRDERLPPIGLLRAAAVPMAVATDCNPGTSPLTSLLL
AMNMAATLFRLTVDECLAGVTRNAARALGLQDSLGVLAAGKRCDLAIWDVERPAELVYRMGFNPLHARVWRGR

Sequences:

>Translated_393_residues
MRVWRNARLATLDPRLPGLGIVEDGAVAADGERIVYVGPAADAPDGETVDCEGRWITPGLIDCHTHLVYAGDRAHEFELR
LAGATYEEIARAGGGIASTVAATRAATEAELTAAARPRLESLVAEGVTTVEIKSGYGLSTAGELKQLRAARALGDAATIV
TSFLGAHAVPSEYAGDPDAYIDLVCEEMIPAVAAEGLADAVDAFCEGIGFAPAQTERVFQAAKRHGLPVKLHAEQLSNLN
GAALAARYGAISADHLEHLDEAGVAAMAKAGTAAVLLPGAFYFLRDERLPPIGLLRAAAVPMAVATDCNPGTSPLTSLLL
AMNMAATLFRLTVDECLAGVTRNAARALGLQDSLGVLAAGKRCDLAIWDVERPAELVYRMGFNPLHARVWRGR
>Mature_393_residues
MRVWRNARLATLDPRLPGLGIVEDGAVAADGERIVYVGPAADAPDGETVDCEGRWITPGLIDCHTHLVYAGDRAHEFELR
LAGATYEEIARAGGGIASTVAATRAATEAELTAAARPRLESLVAEGVTTVEIKSGYGLSTAGELKQLRAARALGDAATIV
TSFLGAHAVPSEYAGDPDAYIDLVCEEMIPAVAAEGLADAVDAFCEGIGFAPAQTERVFQAAKRHGLPVKLHAEQLSNLN
GAALAARYGAISADHLEHLDEAGVAAMAKAGTAAVLLPGAFYFLRDERLPPIGLLRAAAVPMAVATDCNPGTSPLTSLLL
AMNMAATLFRLTVDECLAGVTRNAARALGLQDSLGVLAAGKRCDLAIWDVERPAELVYRMGFNPLHARVWRGR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=367, Percent_Identity=38.4196185286104, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17555004, Length=367, Percent_Identity=33.2425068119891, Blast_Score=201, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 41179; Mature: 41179

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVWRNARLATLDPRLPGLGIVEDGAVAADGERIVYVGPAADAPDGETVDCEGRWITPGL
CCCCCCCCEEEECCCCCCCCEECCCCEEECCCEEEEECCCCCCCCCCEEECCCCEECCCH
IDCHTHLVYAGDRAHEFELRLAGATYEEIARAGGGIASTVAATRAATEAELTAAARPRLE
HHCCEEEEEECCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLVAEGVTTVEIKSGYGLSTAGELKQLRAARALGDAATIVTSFLGAHAVPSEYAGDPDAY
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHH
IDLVCEEMIPAVAAEGLADAVDAFCEGIGFAPAQTERVFQAAKRHGLPVKLHAEQLSNLN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCC
GAALAARYGAISADHLEHLDEAGVAAMAKAGTAAVLLPGAFYFLRDERLPPIGLLRAAAV
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCHHHHHHHHC
PMAVATDCNPGTSPLTSLLLAMNMAATLFRLTVDECLAGVTRNAARALGLQDSLGVLAAG
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCC
KRCDLAIWDVERPAELVYRMGFNPLHARVWRGR
CCCCEEEECCCCHHHHHHHCCCCHHHHHEECCC
>Mature Secondary Structure
MRVWRNARLATLDPRLPGLGIVEDGAVAADGERIVYVGPAADAPDGETVDCEGRWITPGL
CCCCCCCCEEEECCCCCCCCEECCCCEEECCCEEEEECCCCCCCCCCEEECCCCEECCCH
IDCHTHLVYAGDRAHEFELRLAGATYEEIARAGGGIASTVAATRAATEAELTAAARPRLE
HHCCEEEEEECCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLVAEGVTTVEIKSGYGLSTAGELKQLRAARALGDAATIVTSFLGAHAVPSEYAGDPDAY
HHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHH
IDLVCEEMIPAVAAEGLADAVDAFCEGIGFAPAQTERVFQAAKRHGLPVKLHAEQLSNLN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCC
GAALAARYGAISADHLEHLDEAGVAAMAKAGTAAVLLPGAFYFLRDERLPPIGLLRAAAV
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCHHHHHHHHC
PMAVATDCNPGTSPLTSLLLAMNMAATLFRLTVDECLAGVTRNAARALGLQDSLGVLAAG
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCC
KRCDLAIWDVERPAELVYRMGFNPLHARVWRGR
CCCCEEEECCCCHHHHHHHCCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA