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The map label for this gene is zraS [C]

Identifier: 197103909

GI number: 197103909

Start: 447986

End: 449476

Strand: Direct

Name: zraS [C]

Synonym: PHZ_c0443

Alternate gene names: 197103909

Gene position: 447986-449476 (Clockwise)

Preceding gene: 197103908

Following gene: 197103910

Centisome position: 11.21

GC content: 75.72

Gene sequence:

>1491_bases
ATGATGGCGGACGCCCCAGCGCCCAACGAGCCGCCCGCGCGGGACAGACGGCGCCGCCTGTTCTGGCCCGGCGGCCTCTC
GGCGCGCCTGCTGGTCCTGACCGTGCTGTTCGCGGCCCTGGGCGGGCTTATCGCCATCCCGCCGGCCCTGGCCGCCTTCG
AGCGCCAGTGGCTGCTGGACCGGGTGCGGGCCGCCGAGCTGGCCTCGCTGGCCCCCGAGGTGGCCCCGGACCGGGTGGTG
AGCGAACAGCTCAAGACCGAGCTGCTGCGCGGCGCGGGCGTGGAGATCGTGGCCATATCGGTGGACGGGGTCCGCTCGCT
GGTGTTCGCGGGGGCGAGGCCCGCCGAGGCGCCCTATCTCGTGGACCTGCGGCCCCGGGCGGCGGCGGGCCTGGGGGTGT
TCGCGCCGTTCCGGACGCTGTTCGGGCCCGAGGGGCGGCGGGTGCGGGTGGTGGCCGAGCCGCGGTTCCGCGAGGCCGAG
TTCATCGAGTTCGTCGCCACCGACACCGAGCTGAAGCGCGCGCTGGCGGGCTATCTGTGGCGGCTGATCGGCATCGTGGT
CTTCGTCTCGACGCTGGCCGGGGTGCTGGTGTTCGTGGCGCTGAACCTGTTCCTCGTGCGGCCGATGCAGCGGATCACCC
ACGCCATGGAGCGGTTCCGGGCCGACCCCGACGATCCCGCCGCCCGGGTGGAGCTGTCGGGGCGGCGCGACGAGATCGGC
CGCGCCGAGGCCGAGCTCGACCGCATGCAGGCCGACCTGCGCGTGGCGCTGAACTCGCGGGCGCGGCTGGCGGCCCTGGG
CGAGGCGGTGGCCAAGATCAACCACGACCTGAAGAACATGCTCACCTCGGCCCAGATCGCCTCCGAGCGGCTGGCGGCGC
TGCAGGACCCCAAGGTCTCCCAGGCCCTGCCGCGGCTGGAGCGGGCGCTGGACCGGGCGGTGAAACTCGCCTCGGACGTG
CTGGCCTACGGCAAGACCCAGGAGGCCGCGCCCGAGCCGCGGAGGGTCGCCCTGGCCGAGGCGGTGGCCGAGGCGGCGCT
GGAGGCGCGGCTGTCGGACGAGGGCGTGCGGCTGGTCTCGAAGGTGGAGCGCAGCGCGCAGGTCACGGCCGATCCCGACC
AGCTGCACCGGATCCTCGCCAACCTGTTCCGCAACGCCCGCGAGGCGATCGAGCACCAGGAGGGCCGCACGGCGCCCGGC
CGGGTGGAGGTTTCGCTGGCGGCGGCGAACGGCGGCTGCCTGGTGCGGGTGGCCGACAACGGGCCGGGGATTCCCGGCCG
GGTGCGCGAGCGGCTGTTCCAGCCGTTCGCCGGCTCGGGGCGGCCCGACGGGGCGGGCCTGGGCCTGGCCATCGCCCGCG
AGCTGGCGCTGGGCCACGGCGGCGACCTGTCTCTGGCGGCGACGGGCCCCGAGGGCTCGGTCTTCGAGCTGCGCCTGCCC
GGCGCCCCGACCAAGGCTCCCGCCCGCCGGCGGACGAAGAGTCCGGCCTGA

Upstream 100 bases:

>100_bases
CGGACGGTTTTGCTTCGCTCGGCGACGCGGTGGGCGCAAAATAGCAGAGCTGTCAGGGCCTTGCGTTGCCCTGGCCCTCC
GCTCGCATTAACTCGGAAGG

Downstream 100 bases:

>100_bases
CCCCTGAAGGGCAACGCCGTATGCTGTTCAAGTAATCGGTGTCATTGTATATGTAACGGGTCGCAAATTACGGCGATTCG
AATCCCGCATATTCGGGAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MMADAPAPNEPPARDRRRRLFWPGGLSARLLVLTVLFAALGGLIAIPPALAAFERQWLLDRVRAAELASLAPEVAPDRVV
SEQLKTELLRGAGVEIVAISVDGVRSLVFAGARPAEAPYLVDLRPRAAAGLGVFAPFRTLFGPEGRRVRVVAEPRFREAE
FIEFVATDTELKRALAGYLWRLIGIVVFVSTLAGVLVFVALNLFLVRPMQRITHAMERFRADPDDPAARVELSGRRDEIG
RAEAELDRMQADLRVALNSRARLAALGEAVAKINHDLKNMLTSAQIASERLAALQDPKVSQALPRLERALDRAVKLASDV
LAYGKTQEAAPEPRRVALAEAVAEAALEARLSDEGVRLVSKVERSAQVTADPDQLHRILANLFRNAREAIEHQEGRTAPG
RVEVSLAAANGGCLVRVADNGPGIPGRVRERLFQPFAGSGRPDGAGLGLAIARELALGHGGDLSLAATGPEGSVFELRLP
GAPTKAPARRRTKSPA

Sequences:

>Translated_496_residues
MMADAPAPNEPPARDRRRRLFWPGGLSARLLVLTVLFAALGGLIAIPPALAAFERQWLLDRVRAAELASLAPEVAPDRVV
SEQLKTELLRGAGVEIVAISVDGVRSLVFAGARPAEAPYLVDLRPRAAAGLGVFAPFRTLFGPEGRRVRVVAEPRFREAE
FIEFVATDTELKRALAGYLWRLIGIVVFVSTLAGVLVFVALNLFLVRPMQRITHAMERFRADPDDPAARVELSGRRDEIG
RAEAELDRMQADLRVALNSRARLAALGEAVAKINHDLKNMLTSAQIASERLAALQDPKVSQALPRLERALDRAVKLASDV
LAYGKTQEAAPEPRRVALAEAVAEAALEARLSDEGVRLVSKVERSAQVTADPDQLHRILANLFRNAREAIEHQEGRTAPG
RVEVSLAAANGGCLVRVADNGPGIPGRVRERLFQPFAGSGRPDGAGLGLAIARELALGHGGDLSLAATGPEGSVFELRLP
GAPTKAPARRRTKSPA
>Mature_496_residues
MMADAPAPNEPPARDRRRRLFWPGGLSARLLVLTVLFAALGGLIAIPPALAAFERQWLLDRVRAAELASLAPEVAPDRVV
SEQLKTELLRGAGVEIVAISVDGVRSLVFAGARPAEAPYLVDLRPRAAAGLGVFAPFRTLFGPEGRRVRVVAEPRFREAE
FIEFVATDTELKRALAGYLWRLIGIVVFVSTLAGVLVFVALNLFLVRPMQRITHAMERFRADPDDPAARVELSGRRDEIG
RAEAELDRMQADLRVALNSRARLAALGEAVAKINHDLKNMLTSAQIASERLAALQDPKVSQALPRLERALDRAVKLASDV
LAYGKTQEAAPEPRRVALAEAVAEAALEARLSDEGVRLVSKVERSAQVTADPDQLHRILANLFRNAREAIEHQEGRTAPG
RVEVSLAAANGGCLVRVADNGPGIPGRVRERLFQPFAGSGRPDGAGLGLAIARELALGHGGDLSLAATGPEGSVFELRLP
GAPTKAPARRRTKSPA

Specific function: Member of the two-component regulatory system RT0603/RT0550 [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=27.3469387755102, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=26.8085106382979, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=29.2576419213974, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=30.6034482758621, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=296, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=27.1493212669683, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53339; Mature: 53339

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADAPAPNEPPARDRRRRLFWPGGLSARLLVLTVLFAALGGLIAIPPALAAFERQWLLD
CCCCCCCCCCCCCHHHHCEECCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHH
RVRAAELASLAPEVAPDRVVSEQLKTELLRGAGVEIVAISVDGVRSLVFAGARPAEAPYL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCCCCCEE
VDLRPRAAAGLGVFAPFRTLFGPEGRRVRVVAEPRFREAEFIEFVATDTELKRALAGYLW
EECCCCHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHH
RLIGIVVFVSTLAGVLVFVALNLFLVRPMQRITHAMERFRADPDDPAARVELSGRRDEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHH
RAEAELDRMQADLRVALNSRARLAALGEAVAKINHDLKNMLTSAQIASERLAALQDPKVS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QALPRLERALDRAVKLASDVLAYGKTQEAAPEPRRVALAEAVAEAALEARLSDEGVRLVS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KVERSAQVTADPDQLHRILANLFRNAREAIEHQEGRTAPGRVEVSLAAANGGCLVRVADN
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCC
GPGIPGRVRERLFQPFAGSGRPDGAGLGLAIARELALGHGGDLSLAATGPEGSVFELRLP
CCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECC
GAPTKAPARRRTKSPA
CCCCCCCHHCCCCCCC
>Mature Secondary Structure
MMADAPAPNEPPARDRRRRLFWPGGLSARLLVLTVLFAALGGLIAIPPALAAFERQWLLD
CCCCCCCCCCCCCHHHHCEECCCCCCHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHH
RVRAAELASLAPEVAPDRVVSEQLKTELLRGAGVEIVAISVDGVRSLVFAGARPAEAPYL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCCCCCEE
VDLRPRAAAGLGVFAPFRTLFGPEGRRVRVVAEPRFREAEFIEFVATDTELKRALAGYLW
EECCCCHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHH
RLIGIVVFVSTLAGVLVFVALNLFLVRPMQRITHAMERFRADPDDPAARVELSGRRDEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHH
RAEAELDRMQADLRVALNSRARLAALGEAVAKINHDLKNMLTSAQIASERLAALQDPKVS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QALPRLERALDRAVKLASDVLAYGKTQEAAPEPRRVALAEAVAEAALEARLSDEGVRLVS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KVERSAQVTADPDQLHRILANLFRNAREAIEHQEGRTAPGRVEVSLAAANGGCLVRVADN
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCC
GPGIPGRVRERLFQPFAGSGRPDGAGLGLAIARELALGHGGDLSLAATGPEGSVFELRLP
CCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECC
GAPTKAPARRRTKSPA
CCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA