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The map label for this gene is putA [H]

Identifier: 197103805

GI number: 197103805

Start: 338107

End: 341202

Strand: Direct

Name: putA [H]

Synonym: PHZ_c0339

Alternate gene names: 197103805

Gene position: 338107-341202 (Clockwise)

Preceding gene: 197103803

Following gene: 197103806

Centisome position: 8.46

GC content: 73.39

Gene sequence:

>3096_bases
TTGCCGTTCGATCATCTGGATGCCGGCAAGTTCGCCGACGAACGTACGGTCCTGACCAGGGCGCTGGCCGCCCGGCCGCT
CAGCCCGCAGGACCGCGAGGCGGTCCGGCAGGAGGCCGAGGCTCTGGTCCGCGCCGCGCGCAAGGCGGCCCGCAAGCAGG
GAGTGGTCGAGAGCTTCCTGCAGGAGTTCAGCCTCTCCACCCGCGAGGGCCTGGCCCTGATGTGCCTGGCCGAGGCCCTG
CTGCGCACCCCCGACGAGGAGACCCGCGACCGCCTGATCGCCGAGAAGATCGCCTCGGCCGACTGGGCCAGCCACGCCGG
CCGCTCGGACTCGCTGCTGGTCAACGCCTCCACCTGGAGCCTGATGCTCACCGGCCGGCTGATCGACCCGGACGAGGAGG
CCAGGAACGACCTGCCGGGCTTCATCAAGCGCCTGGCCGGGCGCCTGGGCGAGCCCGTCATCCGCAAGGCCGTCGGCGCC
GCCGTCCGCATCATGGGCGAGCAGTTCGTCCTGGGCGCCACCATCGAGAAGGCGATCCGCCGGGCCGCGGCCGACGGCTT
CGTCTGCTCGTTCGACATGCTGGGCGAGGGGGCCCGCACCGACGCCGACGCCGACCGCTACGAAGCCGCCTACGCCGAGG
CCATCCGCGTCGTCGGCAAGTCCGCGACCGGTCAGGGCCCCGAGGCCGGGCACGGCGTCTCGGTGAAGCTGTCGGCCCTG
TCGCCCCGCTACGAAGCCCGCCAGGCTGAGCGGGTGTTCGCCGATCTCTATCCTCGGATCCTGCGCCTGGCTCAGATGGG
GGCGGAGGCCGACATCAACCTGACCCTCGACGCCGAGGAGGCCGACCGCCTCGTCATCTCGCTCCAGCTCCTGGATCGGC
TCGCCCGCGAGCCGGCCCTGCGAGACTGGAAGGGCCTCGGCCTCGCCGTCCAGGCCTACCAGAAGCGCGGCCCCGAGGTG
ATCGCCGCCGTCGCCGACATCGCCCGCTCCAGCGGCCGCCGGCTGATGGTTCGCCTCGTGAAGGGCGCCTACTGGGATTC
CGAGATCAAGCGCGCCCAGGTGGCCGGCCTGTCCGGCTATCCGGTGTTCACCACCAAGGCGGCGACGGACCTGTCCTATC
TCGTCTGCGCCAGGGCCCTGCTGGCCGCCGCCCCCGCGCTCTACGCCCAGTTCGCCACCCACAACGCCCACACCCTGGCC
GCCGTCCGCCAGATGGCCGCCCAGGCCCAGGTGAAGTTCGAGTTCCAGCGTCTGCACGGCATGGGCGAGGCGCTCTACGG
CGCCGCCCAGGAGCGCTATGGCGACTTCCCGCTGCGCGTCTACGCCCCCGTCGGCAGCCACGAGGACCTCCTGCCCTACC
TCGTCCGCCGCCTGCTGGAGAACGGCGCCAACACCTCCTTCGTCCATGCCCTGCTCGACGAGAAGACCCCGGTCTCCAAG
GTCGTCGTGGACCCGATCTCGGCCGTGGAGGCCGCCGGCGGCGCCCCGCACCCGCGCATCCCGCTGCCGCGCGACCTCTA
CGGACCGGCCCGGAAGAACTCCGAGGGCCTCGACCTGTCGATCAAGGCCGTGCGCGACGACCTGACCGCCGCCGTCGCGC
GGCTCGACGGCGAGTCGCTCAAGGGCGCGCCCATCGTGTCGGGCCGCCTGCTGACGGACGGGGAAGGCGCCGAGGCCCGC
TCGCCCGCCGAGCTCTCCCGCGTGATCGGCCGGACCTGGCAGGCGAGCCCCAGGCAGGTGGACGAGGCTTTCGCCGTCGC
CCGCGAGGCGCAGCCCGGCTGGGACGCCCTCGGCGGCGAGGGCCGCGCCAAGGTGCTGCGCGCCATGGGCGATGCGCTGG
AGGCCCATCGCGAGCGCCTGATCGCCATCTGCGTGCGGGAGGCCGGCAAGACCCTGGCCGACGCCATCGCCGAGGTGCGC
GAGGCCGCCGATTTCTGCCGCTACTACGCCCACCTCGCAGAGCGCCAGTTCGCCAGCCCTGAGACCCTGCGCGGGCCCGT
CGGCGAGACGAACCAGCTCCAGCTCCACGGCCGCGGCGTGTTCGTCTGCATCAGCCCCTGGAACTTCCCCCTGGCCATCT
TCACCGGCCAGGTCGCGGCGGCGCTCGCCGCCGGCAACGGCGTGCTGGCCAAGCCCGCCGAGCAGACCCCGATCATCGCC
GCCGAGGCGGTCAGGCTGTTCCACGCCGCCGGCGCGCCAGCCGGCCTGCTGCACCTGCTGCCCGGCGACGGCGCCGTGGT
CGGCCAGGCCCTCGTCTCGCATCCGGGCTGCGACGGCGTGGCCTTCACCGGCGGCACCGACACGGCCTGGGCGATCAACC
GCACCCTGGCGGCCCGCCAGGGGCCGATCGTGCCGTTCATCGCCGAGACCGGCGGGCTGAACGCCATGTTCGTCGACACC
ACGGCCCTGCGCGAACAGGTCATCGACGACGTGTTGCTGTCGGGCTTCGGCTCGGCGGGCCAGCGCTGCTCGGCCCTGCG
CATCCTGTTCCTGCCGCACGAGACCGCCGACGCCCTGCTCGACGGCCTGAAGGGGGCCATGCGGACGCTGGTGGTGACCG
ATCCCGCCGACCCGCGCGCCGATGTCGGGCCGGTGATCGACGCCGAGGCCAAGGCCGCCCTCGAGGCCCACGTGCAGCGG
CTGGAGGCCGAGGCGCGGGTGCTGGCCCGGTTGGACGTCCCCGCGGGCGGGCATTTCTTCGCCCCGACACTGGCCGAGAT
CCCGGACGCGAGCTTCCTGGGCAAGGAGGTGTTCGGCCCGATCCTGCACGTGGTCCGCTACGATCCCGCCCGCCTCGCCG
AGGCCGCCGCGCCGCTGGTCCAGGCCCGCTACGGCCTGACGCTGGGCGTCCATTCCCGCATCGAAGCCTTCGCCGAGGAG
GTCCAGCGGGCGGTCCCGGCCGGCAACGCCTACGTCAACCGCTCGATGATCGGCGCGGTCGTCGGGGTCCAGCCGTTCGG
CGGCGAAGGCCTCTCGGGAACCGGCCCCAAGGCCGGCGGGCCGCACGCCCTGCTGCGCTATGCGGTGGAACGGGCGGTCA
GCGTCAACATCACCGCCCAGGGCGGCGATCCGGCCCTGCTCAACCTCGACGCCTGA

Upstream 100 bases:

>100_bases
CCCGTTTCCGCCGTGGAAGCTGCGGCGACCTCGCCGCCGAACCGTGATACATTCGGCGCTAAGTACCATATCCCGAATGC
TGTCGCAGCAGGAGGCTCCC

Downstream 100 bases:

>100_bases
CGGCGCAGCCGGACGGCCCGAGCCGCGTTCTACATTCCTGAGCCGGCCCGCGCCGGCGCGAGGGATGCCTATGACATTGC
AGCAGGCCCTGGCCTTCGGG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1031; Mature: 1030

Protein sequence:

>1031_residues
MPFDHLDAGKFADERTVLTRALAARPLSPQDREAVRQEAEALVRAARKAARKQGVVESFLQEFSLSTREGLALMCLAEAL
LRTPDEETRDRLIAEKIASADWASHAGRSDSLLVNASTWSLMLTGRLIDPDEEARNDLPGFIKRLAGRLGEPVIRKAVGA
AVRIMGEQFVLGATIEKAIRRAAADGFVCSFDMLGEGARTDADADRYEAAYAEAIRVVGKSATGQGPEAGHGVSVKLSAL
SPRYEARQAERVFADLYPRILRLAQMGAEADINLTLDAEEADRLVISLQLLDRLAREPALRDWKGLGLAVQAYQKRGPEV
IAAVADIARSSGRRLMVRLVKGAYWDSEIKRAQVAGLSGYPVFTTKAATDLSYLVCARALLAAAPALYAQFATHNAHTLA
AVRQMAAQAQVKFEFQRLHGMGEALYGAAQERYGDFPLRVYAPVGSHEDLLPYLVRRLLENGANTSFVHALLDEKTPVSK
VVVDPISAVEAAGGAPHPRIPLPRDLYGPARKNSEGLDLSIKAVRDDLTAAVARLDGESLKGAPIVSGRLLTDGEGAEAR
SPAELSRVIGRTWQASPRQVDEAFAVAREAQPGWDALGGEGRAKVLRAMGDALEAHRERLIAICVREAGKTLADAIAEVR
EAADFCRYYAHLAERQFASPETLRGPVGETNQLQLHGRGVFVCISPWNFPLAIFTGQVAAALAAGNGVLAKPAEQTPIIA
AEAVRLFHAAGAPAGLLHLLPGDGAVVGQALVSHPGCDGVAFTGGTDTAWAINRTLAARQGPIVPFIAETGGLNAMFVDT
TALREQVIDDVLLSGFGSAGQRCSALRILFLPHETADALLDGLKGAMRTLVVTDPADPRADVGPVIDAEAKAALEAHVQR
LEAEARVLARLDVPAGGHFFAPTLAEIPDASFLGKEVFGPILHVVRYDPARLAEAAAPLVQARYGLTLGVHSRIEAFAEE
VQRAVPAGNAYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHALLRYAVERAVSVNITAQGGDPALLNLDA

Sequences:

>Translated_1031_residues
MPFDHLDAGKFADERTVLTRALAARPLSPQDREAVRQEAEALVRAARKAARKQGVVESFLQEFSLSTREGLALMCLAEAL
LRTPDEETRDRLIAEKIASADWASHAGRSDSLLVNASTWSLMLTGRLIDPDEEARNDLPGFIKRLAGRLGEPVIRKAVGA
AVRIMGEQFVLGATIEKAIRRAAADGFVCSFDMLGEGARTDADADRYEAAYAEAIRVVGKSATGQGPEAGHGVSVKLSAL
SPRYEARQAERVFADLYPRILRLAQMGAEADINLTLDAEEADRLVISLQLLDRLAREPALRDWKGLGLAVQAYQKRGPEV
IAAVADIARSSGRRLMVRLVKGAYWDSEIKRAQVAGLSGYPVFTTKAATDLSYLVCARALLAAAPALYAQFATHNAHTLA
AVRQMAAQAQVKFEFQRLHGMGEALYGAAQERYGDFPLRVYAPVGSHEDLLPYLVRRLLENGANTSFVHALLDEKTPVSK
VVVDPISAVEAAGGAPHPRIPLPRDLYGPARKNSEGLDLSIKAVRDDLTAAVARLDGESLKGAPIVSGRLLTDGEGAEAR
SPAELSRVIGRTWQASPRQVDEAFAVAREAQPGWDALGGEGRAKVLRAMGDALEAHRERLIAICVREAGKTLADAIAEVR
EAADFCRYYAHLAERQFASPETLRGPVGETNQLQLHGRGVFVCISPWNFPLAIFTGQVAAALAAGNGVLAKPAEQTPIIA
AEAVRLFHAAGAPAGLLHLLPGDGAVVGQALVSHPGCDGVAFTGGTDTAWAINRTLAARQGPIVPFIAETGGLNAMFVDT
TALREQVIDDVLLSGFGSAGQRCSALRILFLPHETADALLDGLKGAMRTLVVTDPADPRADVGPVIDAEAKAALEAHVQR
LEAEARVLARLDVPAGGHFFAPTLAEIPDASFLGKEVFGPILHVVRYDPARLAEAAAPLVQARYGLTLGVHSRIEAFAEE
VQRAVPAGNAYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHALLRYAVERAVSVNITAQGGDPALLNLDA
>Mature_1030_residues
PFDHLDAGKFADERTVLTRALAARPLSPQDREAVRQEAEALVRAARKAARKQGVVESFLQEFSLSTREGLALMCLAEALL
RTPDEETRDRLIAEKIASADWASHAGRSDSLLVNASTWSLMLTGRLIDPDEEARNDLPGFIKRLAGRLGEPVIRKAVGAA
VRIMGEQFVLGATIEKAIRRAAADGFVCSFDMLGEGARTDADADRYEAAYAEAIRVVGKSATGQGPEAGHGVSVKLSALS
PRYEARQAERVFADLYPRILRLAQMGAEADINLTLDAEEADRLVISLQLLDRLAREPALRDWKGLGLAVQAYQKRGPEVI
AAVADIARSSGRRLMVRLVKGAYWDSEIKRAQVAGLSGYPVFTTKAATDLSYLVCARALLAAAPALYAQFATHNAHTLAA
VRQMAAQAQVKFEFQRLHGMGEALYGAAQERYGDFPLRVYAPVGSHEDLLPYLVRRLLENGANTSFVHALLDEKTPVSKV
VVDPISAVEAAGGAPHPRIPLPRDLYGPARKNSEGLDLSIKAVRDDLTAAVARLDGESLKGAPIVSGRLLTDGEGAEARS
PAELSRVIGRTWQASPRQVDEAFAVAREAQPGWDALGGEGRAKVLRAMGDALEAHRERLIAICVREAGKTLADAIAEVRE
AADFCRYYAHLAERQFASPETLRGPVGETNQLQLHGRGVFVCISPWNFPLAIFTGQVAAALAAGNGVLAKPAEQTPIIAA
EAVRLFHAAGAPAGLLHLLPGDGAVVGQALVSHPGCDGVAFTGGTDTAWAINRTLAARQGPIVPFIAETGGLNAMFVDTT
ALREQVIDDVLLSGFGSAGQRCSALRILFLPHETADALLDGLKGAMRTLVVTDPADPRADVGPVIDAEAKAALEAHVQRL
EAEARVLARLDVPAGGHFFAPTLAEIPDASFLGKEVFGPILHVVRYDPARLAEAAAPLVQARYGLTLGVHSRIEAFAEEV
QRAVPAGNAYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHALLRYAVERAVSVNITAQGGDPALLNLDA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=510, Percent_Identity=29.6078431372549, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI25777734, Length=510, Percent_Identity=29.6078431372549, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI12007648, Length=481, Percent_Identity=28.6902286902287, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI238859541, Length=473, Percent_Identity=30.0211416490486, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI25777732, Length=461, Percent_Identity=27.9826464208243, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI21614513, Length=428, Percent_Identity=29.2056074766355, Blast_Score=150, Evalue=7e-36,
Organism=Homo sapiens, GI153266822, Length=445, Percent_Identity=27.8651685393258, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI21361176, Length=460, Percent_Identity=27.6086956521739, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI25777724, Length=437, Percent_Identity=28.604118993135, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI238814322, Length=432, Percent_Identity=27.5462962962963, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25777728, Length=429, Percent_Identity=28.9044289044289, Blast_Score=140, Evalue=8e-33,
Organism=Homo sapiens, GI25777730, Length=468, Percent_Identity=27.7777777777778, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI188035924, Length=486, Percent_Identity=26.9547325102881, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI115387104, Length=464, Percent_Identity=25, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128093, Length=467, Percent_Identity=27.4089935760171, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI310128103, Length=467, Percent_Identity=27.4089935760171, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI4507229, Length=439, Percent_Identity=27.7904328018223, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI25952152, Length=475, Percent_Identity=26.7368421052632, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI25777721, Length=452, Percent_Identity=27.4336283185841, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI11095441, Length=444, Percent_Identity=26.8018018018018, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI310128091, Length=385, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI310128087, Length=291, Percent_Identity=28.1786941580756, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI301500698, Length=273, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI206597441, Length=348, Percent_Identity=25.2873563218391, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI206597439, Length=348, Percent_Identity=25.2873563218391, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI22907049, Length=348, Percent_Identity=25.2873563218391, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4502043, Length=328, Percent_Identity=28.3536585365854, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI238814371, Length=328, Percent_Identity=28.3536585365854, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI71773324, Length=328, Percent_Identity=28.3536585365854, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI310128089, Length=322, Percent_Identity=26.3975155279503, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI310128099, Length=232, Percent_Identity=28.0172413793103, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI310128101, Length=217, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI73695881, Length=328, Percent_Identity=27.1341463414634, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI73695879, Length=328, Percent_Identity=27.1341463414634, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=9e-12,
Organism=Homo sapiens, GI310128097, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787250, Length=1026, Percent_Identity=50.3898635477583, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=424, Percent_Identity=32.7830188679245, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789015, Length=494, Percent_Identity=28.9473684210526, Blast_Score=166, Evalue=9e-42,
Organism=Escherichia coli, GI1788042, Length=461, Percent_Identity=31.0195227765727, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1787684, Length=446, Percent_Identity=30.4932735426009, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786504, Length=477, Percent_Identity=27.4633123689727, Blast_Score=146, Evalue=7e-36,
Organism=Escherichia coli, GI1787558, Length=451, Percent_Identity=29.0465631929047, Blast_Score=146, Evalue=7e-36,
Organism=Escherichia coli, GI1787715, Length=488, Percent_Identity=29.7131147540984, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87082295, Length=505, Percent_Identity=26.1386138613861, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI87081926, Length=401, Percent_Identity=26.4339152119701, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI1787653, Length=379, Percent_Identity=26.9129287598945, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534447, Length=515, Percent_Identity=31.0679611650485, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI115532534, Length=419, Percent_Identity=32.4582338902148, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25143874, Length=455, Percent_Identity=28.1318681318681, Blast_Score=149, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=496, Percent_Identity=27.6209677419355, Blast_Score=149, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=455, Percent_Identity=28.1318681318681, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI115534176, Length=507, Percent_Identity=27.2189349112426, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17562198, Length=475, Percent_Identity=28.6315789473684, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25144435, Length=475, Percent_Identity=27.5789473684211, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32564736, Length=424, Percent_Identity=28.5377358490566, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI32564151, Length=448, Percent_Identity=29.0178571428571, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=492, Percent_Identity=26.0162601626016, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=468, Percent_Identity=25.8547008547009, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534119, Length=447, Percent_Identity=25.9507829977629, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71995613, Length=403, Percent_Identity=25.5583126550869, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71986308, Length=453, Percent_Identity=26.7108167770419, Blast_Score=109, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71990744, Length=338, Percent_Identity=28.4023668639053, Blast_Score=97, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320917, Length=467, Percent_Identity=30.406852248394, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=484, Percent_Identity=28.7190082644628, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323821, Length=484, Percent_Identity=28.099173553719, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321826, Length=528, Percent_Identity=27.2727272727273, Blast_Score=151, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=492, Percent_Identity=27.8455284552846, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324950, Length=446, Percent_Identity=25.5605381165919, Blast_Score=135, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6325196, Length=403, Percent_Identity=27.5434243176179, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321828, Length=466, Percent_Identity=26.1802575107296, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24668425, Length=508, Percent_Identity=28.740157480315, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24668417, Length=508, Percent_Identity=28.740157480315, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24668413, Length=508, Percent_Identity=28.740157480315, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281362580, Length=458, Percent_Identity=27.7292576419214, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI62472918, Length=458, Percent_Identity=27.7292576419214, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI62472926, Length=458, Percent_Identity=27.7292576419214, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI62472936, Length=458, Percent_Identity=27.7292576419214, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21356737, Length=458, Percent_Identity=27.7292576419214, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28571798, Length=491, Percent_Identity=27.4949083503055, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571796, Length=491, Percent_Identity=27.4949083503055, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571794, Length=491, Percent_Identity=27.4949083503055, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571802, Length=491, Percent_Identity=27.4949083503055, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571800, Length=491, Percent_Identity=27.4949083503055, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571806, Length=491, Percent_Identity=27.4949083503055, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24585660, Length=494, Percent_Identity=27.1255060728745, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI20129399, Length=464, Percent_Identity=26.5086206896552, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24666674, Length=463, Percent_Identity=26.3498920086393, Blast_Score=130, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28574525, Length=500, Percent_Identity=24.2, Blast_Score=128, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24650465, Length=464, Percent_Identity=24.3534482758621, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24638878, Length=444, Percent_Identity=25, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24638876, Length=444, Percent_Identity=25, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI45552499, Length=415, Percent_Identity=24.8192771084337, Blast_Score=85, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281360303, Length=411, Percent_Identity=24.8175182481752, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 109647; Mature: 109516

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDHLDAGKFADERTVLTRALAARPLSPQDREAVRQEAEALVRAARKAARKQGVVESFL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEFSLSTREGLALMCLAEALLRTPDEETRDRLIAEKIASADWASHAGRSDSLLVNASTWS
HHHCCCHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCEEEECCCEE
LMLTGRLIDPDEEARNDLPGFIKRLAGRLGEPVIRKAVGAAVRIMGEQFVLGATIEKAIR
EEEECCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHH
RAAADGFVCSFDMLGEGARTDADADRYEAAYAEAIRVVGKSATGQGPEAGHGVSVKLSAL
HHHCCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
SPRYEARQAERVFADLYPRILRLAQMGAEADINLTLDAEEADRLVISLQLLDRLAREPAL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCC
RDWKGLGLAVQAYQKRGPEVIAAVADIARSSGRRLMVRLVKGAYWDSEIKRAQVAGLSGY
HHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCC
PVFTTKAATDLSYLVCARALLAAAPALYAQFATHNAHTLAAVRQMAAQAQVKFEFQRLHG
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MGEALYGAAQERYGDFPLRVYAPVGSHEDLLPYLVRRLLENGANTSFVHALLDEKTPVSK
HHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
VVVDPISAVEAAGGAPHPRIPLPRDLYGPARKNSEGLDLSIKAVRDDLTAAVARLDGESL
HHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCC
KGAPIVSGRLLTDGEGAEARSPAELSRVIGRTWQASPRQVDEAFAVAREAQPGWDALGGE
CCCCEECCEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GRAKVLRAMGDALEAHRERLIAICVREAGKTLADAIAEVREAADFCRYYAHLAERQFASP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETLRGPVGETNQLQLHGRGVFVCISPWNFPLAIFTGQVAAALAAGNGVLAKPAEQTPIIA
HHCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AEAVRLFHAAGAPAGLLHLLPGDGAVVGQALVSHPGCDGVAFTGGTDTAWAINRTLAARQ
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCC
GPIVPFIAETGGLNAMFVDTTALREQVIDDVLLSGFGSAGQRCSALRILFLPHETADALL
CCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHH
DGLKGAMRTLVVTDPADPRADVGPVIDAEAKAALEAHVQRLEAEARVLARLDVPAGGHFF
HHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
APTLAEIPDASFLGKEVFGPILHVVRYDPARLAEAAAPLVQARYGLTLGVHSRIEAFAEE
CCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHH
VQRAVPAGNAYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHALLRYAVERAVSVNITAQ
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEEC
GGDPALLNLDA
CCCCEEEEECC
>Mature Secondary Structure 
PFDHLDAGKFADERTVLTRALAARPLSPQDREAVRQEAEALVRAARKAARKQGVVESFL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEFSLSTREGLALMCLAEALLRTPDEETRDRLIAEKIASADWASHAGRSDSLLVNASTWS
HHHCCCHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCEEEECCCEE
LMLTGRLIDPDEEARNDLPGFIKRLAGRLGEPVIRKAVGAAVRIMGEQFVLGATIEKAIR
EEEECCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHH
RAAADGFVCSFDMLGEGARTDADADRYEAAYAEAIRVVGKSATGQGPEAGHGVSVKLSAL
HHHCCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
SPRYEARQAERVFADLYPRILRLAQMGAEADINLTLDAEEADRLVISLQLLDRLAREPAL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCC
RDWKGLGLAVQAYQKRGPEVIAAVADIARSSGRRLMVRLVKGAYWDSEIKRAQVAGLSGY
HHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCC
PVFTTKAATDLSYLVCARALLAAAPALYAQFATHNAHTLAAVRQMAAQAQVKFEFQRLHG
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MGEALYGAAQERYGDFPLRVYAPVGSHEDLLPYLVRRLLENGANTSFVHALLDEKTPVSK
HHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
VVVDPISAVEAAGGAPHPRIPLPRDLYGPARKNSEGLDLSIKAVRDDLTAAVARLDGESL
HHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCC
KGAPIVSGRLLTDGEGAEARSPAELSRVIGRTWQASPRQVDEAFAVAREAQPGWDALGGE
CCCCEECCEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GRAKVLRAMGDALEAHRERLIAICVREAGKTLADAIAEVREAADFCRYYAHLAERQFASP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ETLRGPVGETNQLQLHGRGVFVCISPWNFPLAIFTGQVAAALAAGNGVLAKPAEQTPIIA
HHCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AEAVRLFHAAGAPAGLLHLLPGDGAVVGQALVSHPGCDGVAFTGGTDTAWAINRTLAARQ
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCC
GPIVPFIAETGGLNAMFVDTTALREQVIDDVLLSGFGSAGQRCSALRILFLPHETADALL
CCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHH
DGLKGAMRTLVVTDPADPRADVGPVIDAEAKAALEAHVQRLEAEARVLARLDVPAGGHFF
HHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
APTLAEIPDASFLGKEVFGPILHVVRYDPARLAEAAAPLVQARYGLTLGVHSRIEAFAEE
CCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHH
VQRAVPAGNAYVNRSMIGAVVGVQPFGGEGLSGTGPKAGGPHALLRYAVERAVSVNITAQ
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEEC
GGDPALLNLDA
CCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]