Click here to switch to the map view.

The map label for this gene is hisZ [H]

Identifier: 197103799

GI number: 197103799

Start: 330458

End: 331609

Strand: Direct

Name: hisZ [H]

Synonym: PHZ_c0333

Alternate gene names: 197103799

Gene position: 330458-331609 (Clockwise)

Preceding gene: 197103798

Following gene: 197103800

Centisome position: 8.27

GC content: 78.12

Gene sequence:

>1152_bases
ATGCGCGTCGAGCCGCCCGTGCCGGAGGCGGCGCTCGCCGCCATCCGCGCGCCCCTGGAGGCCGCCGGCGCGACTCGCGC
CGACGCGCCCCTGCTGCAGCCGCTGAACCTCTTCCTGGACTTGGCCGGGGAGGCGATGCGCGCGCGGCTGTTCGTGGTGC
AGGCCGAGGGCGGGGCCGAGGCGTGCCTGCGCCCCGACTTCACCGTCGCCATCGCCCGCGCCCACCTGGAGTCGGGCAGG
CGCGACGGGCGCTATCTCTACGAGGGCGCCGCCTTCCGCGCCTCTGCCGGCGCCGAGCGGCCCGAGGAGTTCCTGCAGGT
GGGGTTGGAGCTGTTCGCCCCCCAGAGCCAGGGGGGCGACGGTGCGGCCGAGGCCGCCGACGCCGAGATCGCCGGCCTGG
CCTGGCGCGCGTGCGCGGCCGGCGGGCGGGCCGACCTCTCCCTGCGGCTCGGCGATGTCGGCCTGTTCGGCCCGTTCATC
GAGAGCCTGTCCCTGGCCGAGGGGCTCGCCGCGCGGCTCAAGCGGGTGGCGGGCCGGCCGCGCCTGCTGCAGGCCGAGCT
GGCGCGCACCGGCGAGACGGCCGGCGGCGCGCGCGGAACCCTGGCCAGCATCCTGTCGGGCCTGTCGCAGGCCGAGGCCG
GCGCCCTGCTGGAGGAGGTCTGGGCCTTGGCCGGCGTCGAGCCCGTGGGCGGCCGCGGGCCGGCCGAGATCGCCGCGCGG
CTGGTGCGCAAGGCCGAGGCGGCCGCCGCGCCGGCGCTCACCGACGACCAGGCGGGCGCCATCCGCGCGTTCATGGCCAT
CGACGATTCGCCCGACGCGGCCCTCGCCCGGGTGGGCGAGCTCGCCGGCCGCAACGACAGGGCGCTGAATGCGGCGCTGG
AGGGCTGGGCGCGGCGCTTGGCCGAGCTCGCCAGGGTCGCCGACCCGCACCGGATGCGGTTCGCCCCCGCCCTCGGCCAC
GCCTTCGACTACTACGACGGCCTGACCTTCGAAGTGGTCAGCGAGGCCCTCGGCCCCGAGCGGCCGGTGGCCGTCGGCGG
CCGCTACGACGGCCTGCTGGCCCGCCTTGGGGCTGGCCTCGGGGGCGGCGAAGGGAGGGCGGTGGGCTGCATGGTCCGGC
CCTGGCGCGCATGGGACGGAGGCGAGCAATGA

Upstream 100 bases:

>100_bases
TGACCGACAACGCCGAGTGGCGCGAGCAGCGGCCCGGCCAGCAGACCATCGCCCGCGCCGAGCTGATCCCCGCCCTGCGC
CGCATCCTGGACGCCGGCTG

Downstream 100 bases:

>100_bases
GCGAGCTGGTCATCGCGGTCCCGTCCAAGGGCCGCCTGAAGGAGCAGGTGGAGGCCTGGCTGGCCGACGCCGGCCTCGAC
CTTTCCGTCACCGGCGGGGC

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRVEPPVPEAALAAIRAPLEAAGATRADAPLLQPLNLFLDLAGEAMRARLFVVQAEGGAEACLRPDFTVAIARAHLESGR
RDGRYLYEGAAFRASAGAERPEEFLQVGLELFAPQSQGGDGAAEAADAEIAGLAWRACAAGGRADLSLRLGDVGLFGPFI
ESLSLAEGLAARLKRVAGRPRLLQAELARTGETAGGARGTLASILSGLSQAEAGALLEEVWALAGVEPVGGRGPAEIAAR
LVRKAEAAAAPALTDDQAGAIRAFMAIDDSPDAALARVGELAGRNDRALNAALEGWARRLAELARVADPHRMRFAPALGH
AFDYYDGLTFEVVSEALGPERPVAVGGRYDGLLARLGAGLGGGEGRAVGCMVRPWRAWDGGEQ

Sequences:

>Translated_383_residues
MRVEPPVPEAALAAIRAPLEAAGATRADAPLLQPLNLFLDLAGEAMRARLFVVQAEGGAEACLRPDFTVAIARAHLESGR
RDGRYLYEGAAFRASAGAERPEEFLQVGLELFAPQSQGGDGAAEAADAEIAGLAWRACAAGGRADLSLRLGDVGLFGPFI
ESLSLAEGLAARLKRVAGRPRLLQAELARTGETAGGARGTLASILSGLSQAEAGALLEEVWALAGVEPVGGRGPAEIAAR
LVRKAEAAAAPALTDDQAGAIRAFMAIDDSPDAALARVGELAGRNDRALNAALEGWARRLAELARVADPHRMRFAPALGH
AFDYYDGLTFEVVSEALGPERPVAVGGRYDGLLARLGAGLGGGEGRAVGCMVRPWRAWDGGEQ
>Mature_383_residues
MRVEPPVPEAALAAIRAPLEAAGATRADAPLLQPLNLFLDLAGEAMRARLFVVQAEGGAEACLRPDFTVAIARAHLESGR
RDGRYLYEGAAFRASAGAERPEEFLQVGLELFAPQSQGGDGAAEAADAEIAGLAWRACAAGGRADLSLRLGDVGLFGPFI
ESLSLAEGLAARLKRVAGRPRLLQAELARTGETAGGARGTLASILSGLSQAEAGALLEEVWALAGVEPVGGRGPAEIAAR
LVRKAEAAAAPALTDDQAGAIRAFMAIDDSPDAALARVGELAGRNDRALNAALEGWARRLAELARVADPHRMRFAPALGH
AFDYYDGLTFEVVSEALGPERPVAVGGRYDGLLARLGAGLGGGEGRAVGCMVRPWRAWDGGEQ

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39692; Mature: 39692

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEPPVPEAALAAIRAPLEAAGATRADAPLLQPLNLFLDLAGEAMRARLFVVQAEGGAE
CCCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCC
ACLRPDFTVAIARAHLESGRRDGRYLYEGAAFRASAGAERPEEFLQVGLELFAPQSQGGD
CCCCCCHHHHHHHHHHHCCCCCCCEEECCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
GAAEAADAEIAGLAWRACAAGGRADLSLRLGDVGLFGPFIESLSLAEGLAARLKRVAGRP
CCHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLLQAELARTGETAGGARGTLASILSGLSQAEAGALLEEVWALAGVEPVGGRGPAEIAAR
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LVRKAEAAAAPALTDDQAGAIRAFMAIDDSPDAALARVGELAGRNDRALNAALEGWARRL
HHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AELARVADPHRMRFAPALGHAFDYYDGLTFEVVSEALGPERPVAVGGRYDGLLARLGAGL
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCHHHHHHHHCCCC
GGGEGRAVGCMVRPWRAWDGGEQ
CCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MRVEPPVPEAALAAIRAPLEAAGATRADAPLLQPLNLFLDLAGEAMRARLFVVQAEGGAE
CCCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCC
ACLRPDFTVAIARAHLESGRRDGRYLYEGAAFRASAGAERPEEFLQVGLELFAPQSQGGD
CCCCCCHHHHHHHHHHHCCCCCCCEEECCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
GAAEAADAEIAGLAWRACAAGGRADLSLRLGDVGLFGPFIESLSLAEGLAARLKRVAGRP
CCHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLLQAELARTGETAGGARGTLASILSGLSQAEAGALLEEVWALAGVEPVGGRGPAEIAAR
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LVRKAEAAAAPALTDDQAGAIRAFMAIDDSPDAALARVGELAGRNDRALNAALEGWARRL
HHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AELARVADPHRMRFAPALGHAFDYYDGLTFEVVSEALGPERPVAVGGRYDGLLARLGAGL
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCHHHHHHHHCCCC
GGGEGRAVGCMVRPWRAWDGGEQ
CCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]