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The map label for this gene is atpA

Identifier: 197103701

GI number: 197103701

Start: 237959

End: 239491

Strand: Direct

Name: atpA

Synonym: PHZ_c0235

Alternate gene names: 197103701

Gene position: 237959-239491 (Clockwise)

Preceding gene: 197103700

Following gene: 197103702

Centisome position: 5.95

GC content: 68.36

Gene sequence:

>1533_bases
ATGGATATCCGCGCCGCCGAAATCTCGGCCATCCTGAAGTCGCAGATCGCCAACTTCGGCGAGGAAGCCGACGTCTCCGA
CGTCGGTTCGGTGCTGTCGGTCGGCGACGGCATCGCCCGCGTCTACGGCCTCGACAACGTCCAGGCTGGCGAGATGGTGG
AATTCCCCTCCGCCGGCGTGAAGGGCATGGCCCTGAACCTCGAACGCGACAACGTCGGCATCGTGATCTTCGGCGAGGAC
CGCGCCATCCGCGAGGGCGACGAAGTCCGCCGCCTCGGCGAGATCGTGGACGTGCCGGTGGGCAAGGGTCTGCTGGGCCG
CGTCGTGAACCCGCTGGGCGAGCCGATCGACGGCAAGGGCCCGATCCAGAACGTGGCCGAACGCCGCCGCGTGGACGTGA
AGGCCCCGGGCATCATCCCGCGCAAGTCGGTGCACGAGCCAGTGCAGACCGGCCTGAAGGCCATCGACACCCTGATCCCG
GTCGGCCGCGGCCAGCGCGAGCTGATCATCGGCGACCGCCAGACCGGCAAGACGGCCGTGGCCGTCGACACCATCCTGAA
CCAGAAGCAGGTCAACGCCGGCGGCGACGAGAGCCAGAAGCTCTACTGCATCTACGTGGCCATCGGTCAGAAGCGCTCGA
CCGTCGCCCAGATCGTGAAGACCCTCGAGGAGCGCGGCGCCCTCGACTACACCATCGTCGTGTCGGCCACGGCCTCCGAG
CCGGCCCCGCTGCAGTTCCTGGCCCCGTTCGCCGGCTGCGCCATGGGCGAGTGGTTCCGCGACAACGGCATGCACGCCGT
GATCATCTATGACGACCTGTCCAAGCAGGCCGTCGCCTACCGCCAGATGTCGCTGCTGCTGCGCCGTCCGCCGGGCCGCG
AAGCCTATCCGGGCGACGTCTTCTACCTGCACTCCCGCCTGCTGGAGCGCGCGGCGAAGCTGAACGAGGACAACGGCCTG
GGCTCGCTGACCGCCCTGCCGATCATCGAGACGCAGGCCAACGACGTGTCGGCCTACATCCCGACCAACGTGATCTCGAT
CACCGACGGCCAGATCTTCCTCGAGACCGACCTGTTCTTCCAGGGCATCCGCCCGGCGGTGAACGTCGGCATCTCGGTCT
CGCGCGTGGGCTCCTCGGCCCAGATCAAGGCGATGAAGACCGCCGCCGGCCCGATCAAGGGCGAGCTCGCCCAGTACCGG
GAAATGGCCGCCTTCGCGAAGTTCGGCTCGGACCTCGACGTCGCCACCCAGCGCCAGCTGGCGCGCGGCGAGCGCCTGAC
CGAGCTCCTGAAGCAGCCGCAGTACTCGCCGCTGGCGGTGGAGGAGCAGGTCGTGTCGGTCTACGCCGGCACCCGCGGCT
ACCTCGACAAGATCCCGACCGCCCAGGTCGGCCGCTTCGAGTCCGAGCTGCTCAGCTACATGCACGCCAAGCACCAGGAC
ATCCTGGACGAGATCCGCACCAAGAAGGACCTCGGCCCGGTGGAGGATCGCCTGAAGTCGGCGCTCGCCGCCTTCGCCGA
CTCCTTCGCCTGA

Upstream 100 bases:

>100_bases
TGGGCGGCATCAAGGTGAAGGTCGGTTCCCGCCTCTTCGACGCTTCGCTCCGTTCGAAGCTCGACTCCCTGAAATTCGCC
CTCAAGAGAGCGTAAAGCCC

Downstream 100 bases:

>100_bases
AGCTGACCGGACCCGGGAGCGAGTAGCAGGCGATGGCCAGCCTCAAGGAGATGCGCAATCGGATCGGAAGCGTGAAGGCC
ACGCAGAAGATCACGAAGGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MDIRAAEISAILKSQIANFGEEADVSDVGSVLSVGDGIARVYGLDNVQAGEMVEFPSAGVKGMALNLERDNVGIVIFGED
RAIREGDEVRRLGEIVDVPVGKGLLGRVVNPLGEPIDGKGPIQNVAERRRVDVKAPGIIPRKSVHEPVQTGLKAIDTLIP
VGRGQRELIIGDRQTGKTAVAVDTILNQKQVNAGGDESQKLYCIYVAIGQKRSTVAQIVKTLEERGALDYTIVVSATASE
PAPLQFLAPFAGCAMGEWFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNEDNGL
GSLTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGISVSRVGSSAQIKAMKTAAGPIKGELAQYR
EMAAFAKFGSDLDVATQRQLARGERLTELLKQPQYSPLAVEEQVVSVYAGTRGYLDKIPTAQVGRFESELLSYMHAKHQD
ILDEIRTKKDLGPVEDRLKSALAAFADSFA

Sequences:

>Translated_510_residues
MDIRAAEISAILKSQIANFGEEADVSDVGSVLSVGDGIARVYGLDNVQAGEMVEFPSAGVKGMALNLERDNVGIVIFGED
RAIREGDEVRRLGEIVDVPVGKGLLGRVVNPLGEPIDGKGPIQNVAERRRVDVKAPGIIPRKSVHEPVQTGLKAIDTLIP
VGRGQRELIIGDRQTGKTAVAVDTILNQKQVNAGGDESQKLYCIYVAIGQKRSTVAQIVKTLEERGALDYTIVVSATASE
PAPLQFLAPFAGCAMGEWFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNEDNGL
GSLTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGISVSRVGSSAQIKAMKTAAGPIKGELAQYR
EMAAFAKFGSDLDVATQRQLARGERLTELLKQPQYSPLAVEEQVVSVYAGTRGYLDKIPTAQVGRFESELLSYMHAKHQD
ILDEIRTKKDLGPVEDRLKSALAAFADSFA
>Mature_510_residues
MDIRAAEISAILKSQIANFGEEADVSDVGSVLSVGDGIARVYGLDNVQAGEMVEFPSAGVKGMALNLERDNVGIVIFGED
RAIREGDEVRRLGEIVDVPVGKGLLGRVVNPLGEPIDGKGPIQNVAERRRVDVKAPGIIPRKSVHEPVQTGLKAIDTLIP
VGRGQRELIIGDRQTGKTAVAVDTILNQKQVNAGGDESQKLYCIYVAIGQKRSTVAQIVKTLEERGALDYTIVVSATASE
PAPLQFLAPFAGCAMGEWFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNEDNGL
GSLTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGISVSRVGSSAQIKAMKTAAGPIKGELAQYR
EMAAFAKFGSDLDVATQRQLARGERLTELLKQPQYSPLAVEEQVVSVYAGTRGYLDKIPTAQVGRFESELLSYMHAKHQD
ILDEIRTKKDLGPVEDRLKSALAAFADSFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=505, Percent_Identity=68.9108910891089, Blast_Score=708, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=505, Percent_Identity=68.9108910891089, Blast_Score=708, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=295, Percent_Identity=28.4745762711864, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913426, Length=295, Percent_Identity=28.135593220339, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI32189394, Length=451, Percent_Identity=23.2815964523282, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1790172, Length=520, Percent_Identity=56.5384615384615, Blast_Score=574, Evalue=1e-165,
Organism=Escherichia coli, GI1790170, Length=440, Percent_Identity=25.6818181818182, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788251, Length=278, Percent_Identity=27.3381294964029, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=505, Percent_Identity=68.7128712871287, Blast_Score=710, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=505, Percent_Identity=68.7128712871287, Blast_Score=709, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=505, Percent_Identity=63.7623762376238, Blast_Score=644, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=293, Percent_Identity=29.0102389078498, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=326, Percent_Identity=26.6871165644172, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=437, Percent_Identity=24.0274599542334, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71988068, Length=77, Percent_Identity=55.8441558441558, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=74, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319370, Length=504, Percent_Identity=69.0476190476191, Blast_Score=718, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=349, Percent_Identity=28.3667621776504, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=406, Percent_Identity=24.384236453202, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=68.4418145956608, Blast_Score=706, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=296, Percent_Identity=29.0540540540541, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646341, Length=296, Percent_Identity=29.0540540540541, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136796, Length=296, Percent_Identity=29.0540540540541, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24638766, Length=449, Percent_Identity=24.4988864142539, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574560, Length=402, Percent_Identity=24.3781094527363, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PHEZH (B4RD45)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002129078.1
- GeneID:   6789725
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c0235
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55211; Mature: 55211

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRAAEISAILKSQIANFGEEADVSDVGSVLSVGDGIARVYGLDNVQAGEMVEFPSAGV
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCCC
KGMALNLERDNVGIVIFGEDRAIREGDEVRRLGEIVDVPVGKGLLGRVVNPLGEPIDGKG
CEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
PIQNVAERRRVDVKAPGIIPRKSVHEPVQTGLKAIDTLIPVGRGQRELIIGDRQTGKTAV
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
AVDTILNQKQVNAGGDESQKLYCIYVAIGQKRSTVAQIVKTLEERGALDYTIVVSATASE
HHHHHHCHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCC
PAPLQFLAPFAGCAMGEWFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHH
FYLHSRLLERAAKLNEDNGLGSLTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFF
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHH
QGIRPAVNVGISVSRVGSSAQIKAMKTAAGPIKGELAQYREMAAFAKFGSDLDVATQRQL
HCCCHHHHCCEEEECCCCCHHEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ARGERLTELLKQPQYSPLAVEEQVVSVYAGTRGYLDKIPTAQVGRFESELLSYMHAKHQD
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ILDEIRTKKDLGPVEDRLKSALAAFADSFA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIRAAEISAILKSQIANFGEEADVSDVGSVLSVGDGIARVYGLDNVQAGEMVEFPSAGV
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCCC
KGMALNLERDNVGIVIFGEDRAIREGDEVRRLGEIVDVPVGKGLLGRVVNPLGEPIDGKG
CEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
PIQNVAERRRVDVKAPGIIPRKSVHEPVQTGLKAIDTLIPVGRGQRELIIGDRQTGKTAV
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
AVDTILNQKQVNAGGDESQKLYCIYVAIGQKRSTVAQIVKTLEERGALDYTIVVSATASE
HHHHHHCHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCC
PAPLQFLAPFAGCAMGEWFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHH
FYLHSRLLERAAKLNEDNGLGSLTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFF
HHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHH
QGIRPAVNVGISVSRVGSSAQIKAMKTAAGPIKGELAQYREMAAFAKFGSDLDVATQRQL
HCCCHHHHCCEEEECCCCCHHEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ARGERLTELLKQPQYSPLAVEEQVVSVYAGTRGYLDKIPTAQVGRFESELLSYMHAKHQD
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ILDEIRTKKDLGPVEDRLKSALAAFADSFA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA