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The map label for this gene is regA [H]

Identifier: 197103692

GI number: 197103692

Start: 227699

End: 228256

Strand: Reverse

Name: regA [H]

Synonym: PHZ_c0226

Alternate gene names: 197103692

Gene position: 228256-227699 (Counterclockwise)

Preceding gene: 197103693

Following gene: 197103684

Centisome position: 5.71

GC content: 72.94

Gene sequence:

>558_bases
ATGACCGATCTCTCCGCCGATATTTCCGCGCTTCCCGACAAGTCCCTGCTGGTGCTCGACGACGACGCGCCGCTCCGCAA
CCGGCTGGGCCGGGCGCTGGAGCAGCGGGGATTCGAGCCCACGCTGGTGGGCAGCGTCGCCGAGGCGATCGCCGCGGTGC
GGGCCAAGCCGCCCGCCTACGCCGTGCTCGACATGCGTCTGGAGGACGGCTCGGGCCTGAAGGTGGTGGAGGCGGTGCGC
GACGCCCGCCCCGACGCCAAGATCATCATGCTGACCGGCTACGGCAACATCGCCACCGCGGTGCAGGCGGTGAAGGCCGG
GGCGGTGGACTACCTCTCCAAGCCCGCCGACGCCGACGACGTGGCCCGCGCCCTGCTGGCCCGCGGCGGCGACGCCCCCG
CGCCCCCCGAGAACCCGATGAGCGCCGACCGGGTGCGCTGGGAGCACATCCAGCGGGTCTACGAGCTCTGCAACCACAAC
GTCTCCGAGACCGCCCGGCGGCTGAACATGCACCGCCGCACCCTGCAGCGGATCCTCGCCAAGCGGGCGCCCCGCTAG

Upstream 100 bases:

>100_bases
ATCGAGGCCGGCTGAACGGCGGCAGCCAAGCTTGCCCTGATGCGTTGAGGTGCGACAGACTGCCGCAGAGCACAGTGAGG
GAGCCCGCCGGGATTTGAGT

Downstream 100 bases:

>100_bases
GCGCGGACGGCCGGCCATGGCGACCTGGGACGACATCCGCGCCGCCGCCCTGCCCCTTCCCGGCGCCGAGGAGGACGTCT
GGTACGGCGAGCCCATGTTC

Product: response regulator(CheY-like receiver domain and a Fis-type HTH domain)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTDLSADISALPDKSLLVLDDDAPLRNRLGRALEQRGFEPTLVGSVAEAIAAVRAKPPAYAVLDMRLEDGSGLKVVEAVR
DARPDAKIIMLTGYGNIATAVQAVKAGAVDYLSKPADADDVARALLARGGDAPAPPENPMSADRVRWEHIQRVYELCNHN
VSETARRLNMHRRTLQRILAKRAPR

Sequences:

>Translated_185_residues
MTDLSADISALPDKSLLVLDDDAPLRNRLGRALEQRGFEPTLVGSVAEAIAAVRAKPPAYAVLDMRLEDGSGLKVVEAVR
DARPDAKIIMLTGYGNIATAVQAVKAGAVDYLSKPADADDVARALLARGGDAPAPPENPMSADRVRWEHIQRVYELCNHN
VSETARRLNMHRRTLQRILAKRAPR
>Mature_184_residues
TDLSADISALPDKSLLVLDDDAPLRNRLGRALEQRGFEPTLVGSVAEAIAAVRAKPPAYAVLDMRLEDGSGLKVVEAVRD
ARPDAKIIMLTGYGNIATAVQAVKAGAVDYLSKPADADDVARALLARGGDAPAPPENPMSADRVRWEHIQRVYELCNHNV
SETARRLNMHRRTLQRILAKRAPR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=139, Percent_Identity=27.3381294964029, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=34.5132743362832, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=30.9090909090909, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=111, Percent_Identity=28.8288288288288, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20110; Mature: 19979

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSADISALPDKSLLVLDDDAPLRNRLGRALEQRGFEPTLVGSVAEAIAAVRAKPPAY
CCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCE
AVLDMRLEDGSGLKVVEAVRDARPDAKIIMLTGYGNIATAVQAVKAGAVDYLSKPADADD
EEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHH
VARALLARGGDAPAPPENPMSADRVRWEHIQRVYELCNHNVSETARRLNMHRRTLQRILA
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KRAPR
HCCCC
>Mature Secondary Structure 
TDLSADISALPDKSLLVLDDDAPLRNRLGRALEQRGFEPTLVGSVAEAIAAVRAKPPAY
CCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCE
AVLDMRLEDGSGLKVVEAVRDARPDAKIIMLTGYGNIATAVQAVKAGAVDYLSKPADADD
EEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHH
VARALLARGGDAPAPPENPMSADRVRWEHIQRVYELCNHNVSETARRLNMHRRTLQRILA
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KRAPR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA