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The map label for this gene is sdhB [H]

Identifier: 197103679

GI number: 197103679

Start: 210893

End: 211675

Strand: Direct

Name: sdhB [H]

Synonym: PHZ_c0213

Alternate gene names: 197103679

Gene position: 210893-211675 (Clockwise)

Preceding gene: 197103678

Following gene: 197103680

Centisome position: 5.28

GC content: 67.94

Gene sequence:

>783_bases
ATGGCCGAGATCCGCCTGCCCAAGAACTCCCGCGTCACCCAGGGCCGCCACCACCCGGCGCCCGCCGGCGCGGCCCGCAC
CAAGACCTTCAAGGTCTACCGCTACGACCCGGACGACGCGGCCAACCCGCGCTGGGACACCTACGAGGTGGACGTGGACG
CCTGCGGCCCGATGGTCCTGGACGTCCTGATCCATATCAAGAACACCATGGACCCGACGCTGACCTTCCGGCGCTCGTGC
CGGGAGGGCGTCTGCGGCTCGTGCGCCATGAACATCGGCGGCCGCAACACGCTCGCCTGCACCCACGGCTGGGAGGAGGT
CCCCGGCCAGGCCGTGCAGATCAGCCCGCTGCCGCACATGCCGGTGGTCAAGGACCTGGTCCCGGACCTGACCCTGTTCT
ACGCCCAGTACGCCTCGATCGAGCCCTGGCTGCACACCAAGACCCCCGAGCCGCAGACCGAGTGGGCGCAGAGCCCCGAG
GACCGCGAGAAGCTGGACGGCCTCTACGAGTGCATCCTGTGCGCCTGCTGCTCCACGAGCTGCCCCAGCTACTGGTGGAA
CCAGGAGAAGTACCTGGGGCCTGCCGCCCTGCTGCACGCCTACCGATGGATCATCGACTCGCGCGACGAGGCCACCGGCG
AGCGCCTGGACGAGCTGGAGGATCCCTTCAAGCTCTACCGCTGCCACACCATCATGAACTGCGCCCAGGTCTGTCCTAAG
GGTCTCAACCCAGCCAAGGCCATCGGGGAAATCAAGAAGCTGCTGGTGGACCGGGTCGTCTGA

Upstream 100 bases:

>100_bases
GACGACCGTCCGGTGCACAACTTCACCATGTCCAACGACATCGCCTACATCCCGCCGAAGGCGCGGGTGTACTAAGGCCA
GCCCCAGGAAGACCCGCCCG

Downstream 100 bases:

>100_bases
CGCCCGGGGCCGCCGGGTTCCGGCGGGGAAAAGTTGACGGGGCCGTCACTTTTGGGCATCGAGGTTCCATGAGCGACGCT
ACGGCGCATGTGGTGATCCT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAEIRLPKNSRVTQGRHHPAPAGAARTKTFKVYRYDPDDAANPRWDTYEVDVDACGPMVLDVLIHIKNTMDPTLTFRRSC
REGVCGSCAMNIGGRNTLACTHGWEEVPGQAVQISPLPHMPVVKDLVPDLTLFYAQYASIEPWLHTKTPEPQTEWAQSPE
DREKLDGLYECILCACCSTSCPSYWWNQEKYLGPAALLHAYRWIIDSRDEATGERLDELEDPFKLYRCHTIMNCAQVCPK
GLNPAKAIGEIKKLLVDRVV

Sequences:

>Translated_260_residues
MAEIRLPKNSRVTQGRHHPAPAGAARTKTFKVYRYDPDDAANPRWDTYEVDVDACGPMVLDVLIHIKNTMDPTLTFRRSC
REGVCGSCAMNIGGRNTLACTHGWEEVPGQAVQISPLPHMPVVKDLVPDLTLFYAQYASIEPWLHTKTPEPQTEWAQSPE
DREKLDGLYECILCACCSTSCPSYWWNQEKYLGPAALLHAYRWIIDSRDEATGERLDELEDPFKLYRCHTIMNCAQVCPK
GLNPAKAIGEIKKLLVDRVV
>Mature_259_residues
AEIRLPKNSRVTQGRHHPAPAGAARTKTFKVYRYDPDDAANPRWDTYEVDVDACGPMVLDVLIHIKNTMDPTLTFRRSCR
EGVCGSCAMNIGGRNTLACTHGWEEVPGQAVQISPLPHMPVVKDLVPDLTLFYAQYASIEPWLHTKTPEPQTEWAQSPED
REKLDGLYECILCACCSTSCPSYWWNQEKYLGPAALLHAYRWIIDSRDEATGERLDELEDPFKLYRCHTIMNCAQVCPKG
LNPAKAIGEIKKLLVDRVV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=242, Percent_Identity=66.1157024793389, Blast_Score=338, Evalue=2e-93,
Organism=Escherichia coli, GI1786943, Length=233, Percent_Identity=55.793991416309, Blast_Score=270, Evalue=8e-74,
Organism=Escherichia coli, GI1790596, Length=225, Percent_Identity=33.7777777777778, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=234, Percent_Identity=63.2478632478632, Blast_Score=324, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=65.948275862069, Blast_Score=323, Evalue=1e-89,
Organism=Drosophila melanogaster, GI17137106, Length=243, Percent_Identity=64.1975308641975, Blast_Score=338, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643156, Length=238, Percent_Identity=63.0252100840336, Blast_Score=318, Evalue=2e-87,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29346; Mature: 29215

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIRLPKNSRVTQGRHHPAPAGAARTKTFKVYRYDPDDAANPRWDTYEVDVDACGPMVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEHHHCCHHHH
DVLIHIKNTMDPTLTFRRSCREGVCGSCAMNIGGRNTLACTHGWEEVPGQAVQISPLPHM
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCEEEECCCHHHCCCCEEEECCCCCC
PVVKDLVPDLTLFYAQYASIEPWLHTKTPEPQTEWAQSPEDREKLDGLYECILCACCSTS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNQEKYLGPAALLHAYRWIIDSRDEATGERLDELEDPFKLYRCHTIMNCAQVCPK
CCCHHCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLNPAKAIGEIKKLLVDRVV
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEIRLPKNSRVTQGRHHPAPAGAARTKTFKVYRYDPDDAANPRWDTYEVDVDACGPMVL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEHHHCCHHHH
DVLIHIKNTMDPTLTFRRSCREGVCGSCAMNIGGRNTLACTHGWEEVPGQAVQISPLPHM
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCEEEECCCHHHCCCCEEEECCCCCC
PVVKDLVPDLTLFYAQYASIEPWLHTKTPEPQTEWAQSPEDREKLDGLYECILCACCSTS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNQEKYLGPAALLHAYRWIIDSRDEATGERLDELEDPFKLYRCHTIMNCAQVCPK
CCCHHCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLNPAKAIGEIKKLLVDRVV
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA