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The map label for this gene is citZ [H]

Identifier: 197103629

GI number: 197103629

Start: 154680

End: 155843

Strand: Direct

Name: citZ [H]

Synonym: PHZ_c0163

Alternate gene names: 197103629

Gene position: 154680-155843 (Clockwise)

Preceding gene: 197103627

Following gene: 197103632

Centisome position: 3.87

GC content: 78.01

Gene sequence:

>1164_bases
ATGCCTCAGCGCGACTGGATTTCCGCCGAAGACGCCCTCGCCCGCCTCGGGGTGCGGCCGCAGACGCTCTACGCCTATGT
CAGCCGCGGCCGGGTGCAGGTGCGGCCCGACCCCGGCGACTCGCGGCGCAGCCTCTATCGCGCGGCCGACATCGCGAACC
TCGCCGAGCGCAAGTCCCGCAGCCGCAAGGCCGCCGACGTCGCCGCCGGCGCGATCAGCTGGGGCGAGCCGGTGCTGGCT
TCCGCGATCACCACCGTTTCGGGCGGGCGGCTCTACTACCGCGGCCGGGACGCCATCCGCCTGGCCGAGACCGAGACCCT
GGAGGCGGTCGCGCGCCTGCTGCGCGGCGGCCACGGCGCGGCCCTGAAACGCACCGACCGGCCCGAGCCGCCGCAGGGGC
CCGACCTGCGCGCGCGGGCGTTCCTGGCGCTCGCCGCCCGGGCCGCGTCCGATCCGCCGGCCCGCGGCCGCGCGCCCCTG
GTGCTGGCGGTCGAGGCGGCCACCCTGCTGGACGTGCTGACCGACGCCGTCGCCGGCCAGGTCGGCGGCGGGGCGATCCA
CAACCGCCTGGCCCTGGCCTGGGGGCAGGGGCCCGGCGGGCCGGGGGCGGACCTGATCCGGCGCATCCTGGTGCTGGTCG
CCGACCATGAGCTGAACGCCTCGGCCTTCGCGGCGCGGGTGGCGGGCTCGACAGGGGCCTCGCTCTCGTCCGCCGCCCTC
GCGGGTCTGGCCACGCTGTCGGGTCCGCGGCATGGCGGGGCGACGGCGGCCGTGCGGACCTTCGTGGCCGAGGCGGCGCA
AGGCGGGCCGGCGGAGGCCATCGCCCGCCGCCTGGCCGAGGATCGGGCGCTGCCGGGCTTCGGCCATCCGCTCTATCCGG
ACGGCGATCCGCGCGCGGCGGCCCTGCTGGACCGGTTCGAGCCGCCGCCGGCGCTCGCCGCGCTCCAGCGGTCCGTGATG
GAGGTCGCGGGCCAGGCGCCGAACGTCGACTTCGCCCTGCTGGCCGCCTGCGAGGCGCTGCGGCTGCCGAAGGACGCGCC
CTTCGCCCTGTTCGCGGTCGCCCGCTGCGCCGGCTGGATCGCCCACGCCATCGAGCAGGGCCAGACCGACGCCCTCATCC
GCCCGCGGGCCCGCTACGTGGGCCCGGAGCCTGAGCTGGTGTGA

Upstream 100 bases:

>100_bases
CTTCAAGTCCGTCCGACATATCGGCCTCCATTGCTCTTGTCGGACGGGAGATTTGCCTCCAGGCTCCTGTCGTCAATCTT
GATCAATATGATCAATATAA

Downstream 100 bases:

>100_bases
CGTCCTCCCCCTCCTCCTGAGGGGGAGGAGTCCTGGCTCTAGGCCCGCCTATGCACGACCTCCTCGGCCTCCAGGGCATG
GTCGAGGCGGCCGACCATCT

Product: citrate synthase

Products: NA

Alternate protein names: Citrate synthase II [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPQRDWISAEDALARLGVRPQTLYAYVSRGRVQVRPDPGDSRRSLYRAADIANLAERKSRSRKAADVAAGAISWGEPVLA
SAITTVSGGRLYYRGRDAIRLAETETLEAVARLLRGGHGAALKRTDRPEPPQGPDLRARAFLALAARAASDPPARGRAPL
VLAVEAATLLDVLTDAVAGQVGGGAIHNRLALAWGQGPGGPGADLIRRILVLVADHELNASAFAARVAGSTGASLSSAAL
AGLATLSGPRHGGATAAVRTFVAEAAQGGPAEAIARRLAEDRALPGFGHPLYPDGDPRAAALLDRFEPPPALAALQRSVM
EVAGQAPNVDFALLAACEALRLPKDAPFALFAVARCAGWIAHAIEQGQTDALIRPRARYVGPEPELV

Sequences:

>Translated_387_residues
MPQRDWISAEDALARLGVRPQTLYAYVSRGRVQVRPDPGDSRRSLYRAADIANLAERKSRSRKAADVAAGAISWGEPVLA
SAITTVSGGRLYYRGRDAIRLAETETLEAVARLLRGGHGAALKRTDRPEPPQGPDLRARAFLALAARAASDPPARGRAPL
VLAVEAATLLDVLTDAVAGQVGGGAIHNRLALAWGQGPGGPGADLIRRILVLVADHELNASAFAARVAGSTGASLSSAAL
AGLATLSGPRHGGATAAVRTFVAEAAQGGPAEAIARRLAEDRALPGFGHPLYPDGDPRAAALLDRFEPPPALAALQRSVM
EVAGQAPNVDFALLAACEALRLPKDAPFALFAVARCAGWIAHAIEQGQTDALIRPRARYVGPEPELV
>Mature_386_residues
PQRDWISAEDALARLGVRPQTLYAYVSRGRVQVRPDPGDSRRSLYRAADIANLAERKSRSRKAADVAAGAISWGEPVLAS
AITTVSGGRLYYRGRDAIRLAETETLEAVARLLRGGHGAALKRTDRPEPPQGPDLRARAFLALAARAASDPPARGRAPLV
LAVEAATLLDVLTDAVAGQVGGGAIHNRLALAWGQGPGGPGADLIRRILVLVADHELNASAFAARVAGSTGASLSSAALA
GLATLSGPRHGGATAAVRTFVAEAAQGGPAEAIARRLAEDRALPGFGHPLYPDGDPRAAALLDRFEPPPALAALQRSVME
VAGQAPNVDFALLAACEALRLPKDAPFALFAVARCAGWIAHAIEQGQTDALIRPRARYVGPEPELV

Specific function: Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect [H]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=218, Percent_Identity=33.4862385321101, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786939, Length=199, Percent_Identity=35.1758793969849, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 40320; Mature: 40189

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQRDWISAEDALARLGVRPQTLYAYVSRGRVQVRPDPGDSRRSLYRAADIANLAERKSR
CCCCCCCCHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SRKAADVAAGAISWGEPVLASAITTVSGGRLYYRGRDAIRLAETETLEAVARLLRGGHGA
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHHHHHHHCCCCCC
ALKRTDRPEPPQGPDLRARAFLALAARAASDPPARGRAPLVLAVEAATLLDVLTDAVAGQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCC
VGGGAIHNRLALAWGQGPGGPGADLIRRILVLVADHELNASAFAARVAGSTGASLSSAAL
CCCCHHHHCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHH
AGLATLSGPRHGGATAAVRTFVAEAAQGGPAEAIARRLAEDRALPGFGHPLYPDGDPRAA
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
ALLDRFEPPPALAALQRSVMEVAGQAPNVDFALLAACEALRLPKDAPFALFAVARCAGWI
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AHAIEQGQTDALIRPRARYVGPEPELV
HHHHHCCCCCCEECCHHHCCCCCCCCC
>Mature Secondary Structure 
PQRDWISAEDALARLGVRPQTLYAYVSRGRVQVRPDPGDSRRSLYRAADIANLAERKSR
CCCCCCCHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SRKAADVAAGAISWGEPVLASAITTVSGGRLYYRGRDAIRLAETETLEAVARLLRGGHGA
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCEEEHHHHHHHHHHHHHCCCCCC
ALKRTDRPEPPQGPDLRARAFLALAARAASDPPARGRAPLVLAVEAATLLDVLTDAVAGQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCC
VGGGAIHNRLALAWGQGPGGPGADLIRRILVLVADHELNASAFAARVAGSTGASLSSAAL
CCCCHHHHCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHH
AGLATLSGPRHGGATAAVRTFVAEAAQGGPAEAIARRLAEDRALPGFGHPLYPDGDPRAA
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
ALLDRFEPPPALAALQRSVMEVAGQAPNVDFALLAACEALRLPKDAPFALFAVARCAGWI
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AHAIEQGQTDALIRPRARYVGPEPELV
HHHHHCCCCCCEECCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8045898; 9387221; 9384377 [H]