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The map label for this gene is luxQ [H]

Identifier: 197103592

GI number: 197103592

Start: 118792

End: 120552

Strand: Direct

Name: luxQ [H]

Synonym: PHZ_c0126

Alternate gene names: 197103592

Gene position: 118792-120552 (Clockwise)

Preceding gene: 197103590

Following gene: 197103593

Centisome position: 2.97

GC content: 72.74

Gene sequence:

>1761_bases
ATGTCGCCCAGTTTCAGTTACCACCGCCTCGCGTCGACCCGGGCCCGGGAACTGCCCATGCGGGTGGGCCTTGCGCTCAT
CATCGGCGCCGGGACCCTGTACCTGACGCAGAGCCCCTGGACCTTCGCCTGGCTGGCGGCGGTGGCGGCGACCCAGCTTC
TCGACCTGCGGCTGACGGCGCCGATGCGCCGCGACCCCGATTTCGTCCCCGACCGCGCCCAGGAGCGGGTCTATCTCGCC
TCGGTGACGCTGAACGTCCTCGTCTACTCCGCCATCACGCCGCTGTGCTGGCTGAAGGGCGGGCTGGAGGGCCACCTCTA
CGCCCTGCTGGTGCCGGCGGCGGGGTTGATCAACGTGGCGCTGCAGGCCCAGTCGGCGCCCAAGATGCTGTGGGCCGGCT
GCACGCCGCACGCCCTCTACCTGGTCAGCCTGCCGGTGCTGTCGATCCTCGTGGAGCAGGACGCCGATGTCGCCGGCATG
GCCTTCGTCGCCGTCGGCGCGAGCCTCTACCTGGCCCACCTGTTCATCGCCGTGCTGCGCAACCGCCAGGCGGCGGTGGC
CCTGGACGAGGCGCTCGGCGAGGCCCAGGCGGCCCGGGCCAGGGCCCAGGAGGCGAGCGCCGCCAAGAGCGAGTTCCTGG
CCACCATGAGCCACGAGATCCGCACACCGCTGAACGGGGTGCTGGGGATGGCCCAGGCCATGGCGCACGATCCGCTGCCC
AGGCGCCAGCGCGAGCGGCTGGAGGTGATCCGCCAGTCGGGCGAGGTGCTGCTGGTGCTGCTGAACGACCTGCTCGACAT
TTCCAAGATCGAGGCCGCCAAGCTGGAGCTCGACCTTGCACCGCTGGATCTGCACGACCTTGCGGCCCAGGCGCAGGAGG
CCTTCGCCCCGCTCGCCGCGTCGAAGGACCTCGAGCTCTCGGTGCGGGCCGCGCCCGAGCTCGCCGGCGCCTGGCGGGCG
GACGCGACGCGGGTGCGGCAGATCCTCTACAACCTGCTCGCCAACGCCGTGAAGTTCACCGAGCGCGGGGCCGTGGCCGC
CGATCTCTTCCTGGACGCGGCGGGCCAGGTCGTGCTGCGCGTCCGCGACACCGGACCGGGCGTCGCGCCCGAGCGGCTGG
ACGCCCTGTTCGAGCGTTTCGTGCAGGCCGAGGCCTCGACGACCCGCCGCTACGGCGGCTCGGGCCTGGGGCTGGCCATC
TCCCGCGACCTCGCCCGGCTGATGGGGGGCGACATCGCCGCGCAGAGCACGCCCGGCGCAGGCTCGACCTTCACCGTCAT
CCTGCCGCTGGACCGCGCCGATGCGCCCGAGGTTGTGGGGCCGGCGGCCGCGCCGGCGGAGGTCGCCGCGATCCGGGTGC
TGGTCGCCGAGGACAACGAGACGAACCAGCTGGTGCTGAAGACCCTGCTGGGCCAGCTCGGGGTCGAGGTCGAGATGACC
GCCGACGGCCACGAGGCGGTCGAGGCCTGGCGGCAGGGGCCTTTCGACCTGATCCTGATGGACGTGCAGATGCCGGTGAT
GGACGGCCTCGCCGCCACCCGCCGCATCCGCGAGATCGAGGCGCAGACCGGCCGGGCGCGCACGCCGATCGTCGCCCTGA
CCGCCAACGCGATGTCGCACCACCTGGTCGAGTACGCGCAGGCCGGCATGGACGGCGTCACGGCCAAGCCGATCGAGCTC
AGCCGGCTGGTGGAACAGATGAACGTCGCCCTGAGCGGCCGCCGCTCGGGTCCGGTGACGGGGGCCACCGCGGCCGCCTG
A

Upstream 100 bases:

>100_bases
CCCTCCTCGCCGGCCGCCGTACGCCTGATTCGAAAAAGGCGGCCTGATTGGAACGCTTGATTAAGCCAACCTGGGAAATG
CTGCAGGCTGGGGAGAGGCA

Downstream 100 bases:

>100_bases
CCAGGCGCCGAAGCGGCGAGGTGCAGCGCGCGCCGTTCTCGCCTATATGTCCGCGGCCATGGGACGTCCGTTCCTCAAGA
TGAACGGGCTCGGCAACGAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MSPSFSYHRLASTRARELPMRVGLALIIGAGTLYLTQSPWTFAWLAAVAATQLLDLRLTAPMRRDPDFVPDRAQERVYLA
SVTLNVLVYSAITPLCWLKGGLEGHLYALLVPAAGLINVALQAQSAPKMLWAGCTPHALYLVSLPVLSILVEQDADVAGM
AFVAVGASLYLAHLFIAVLRNRQAAVALDEALGEAQAARARAQEASAAKSEFLATMSHEIRTPLNGVLGMAQAMAHDPLP
RRQRERLEVIRQSGEVLLVLLNDLLDISKIEAAKLELDLAPLDLHDLAAQAQEAFAPLAASKDLELSVRAAPELAGAWRA
DATRVRQILYNLLANAVKFTERGAVAADLFLDAAGQVVLRVRDTGPGVAPERLDALFERFVQAEASTTRRYGGSGLGLAI
SRDLARLMGGDIAAQSTPGAGSTFTVILPLDRADAPEVVGPAAAPAEVAAIRVLVAEDNETNQLVLKTLLGQLGVEVEMT
ADGHEAVEAWRQGPFDLILMDVQMPVMDGLAATRRIREIEAQTGRARTPIVALTANAMSHHLVEYAQAGMDGVTAKPIEL
SRLVEQMNVALSGRRSGPVTGATAAA

Sequences:

>Translated_586_residues
MSPSFSYHRLASTRARELPMRVGLALIIGAGTLYLTQSPWTFAWLAAVAATQLLDLRLTAPMRRDPDFVPDRAQERVYLA
SVTLNVLVYSAITPLCWLKGGLEGHLYALLVPAAGLINVALQAQSAPKMLWAGCTPHALYLVSLPVLSILVEQDADVAGM
AFVAVGASLYLAHLFIAVLRNRQAAVALDEALGEAQAARARAQEASAAKSEFLATMSHEIRTPLNGVLGMAQAMAHDPLP
RRQRERLEVIRQSGEVLLVLLNDLLDISKIEAAKLELDLAPLDLHDLAAQAQEAFAPLAASKDLELSVRAAPELAGAWRA
DATRVRQILYNLLANAVKFTERGAVAADLFLDAAGQVVLRVRDTGPGVAPERLDALFERFVQAEASTTRRYGGSGLGLAI
SRDLARLMGGDIAAQSTPGAGSTFTVILPLDRADAPEVVGPAAAPAEVAAIRVLVAEDNETNQLVLKTLLGQLGVEVEMT
ADGHEAVEAWRQGPFDLILMDVQMPVMDGLAATRRIREIEAQTGRARTPIVALTANAMSHHLVEYAQAGMDGVTAKPIEL
SRLVEQMNVALSGRRSGPVTGATAAA
>Mature_585_residues
SPSFSYHRLASTRARELPMRVGLALIIGAGTLYLTQSPWTFAWLAAVAATQLLDLRLTAPMRRDPDFVPDRAQERVYLAS
VTLNVLVYSAITPLCWLKGGLEGHLYALLVPAAGLINVALQAQSAPKMLWAGCTPHALYLVSLPVLSILVEQDADVAGMA
FVAVGASLYLAHLFIAVLRNRQAAVALDEALGEAQAARARAQEASAAKSEFLATMSHEIRTPLNGVLGMAQAMAHDPLPR
RQRERLEVIRQSGEVLLVLLNDLLDISKIEAAKLELDLAPLDLHDLAAQAQEAFAPLAASKDLELSVRAAPELAGAWRAD
ATRVRQILYNLLANAVKFTERGAVAADLFLDAAGQVVLRVRDTGPGVAPERLDALFERFVQAEASTTRRYGGSGLGLAIS
RDLARLMGGDIAAQSTPGAGSTFTVILPLDRADAPEVVGPAAAPAEVAAIRVLVAEDNETNQLVLKTLLGQLGVEVEMTA
DGHEAVEAWRQGPFDLILMDVQMPVMDGLAATRRIREIEAQTGRARTPIVALTANAMSHHLVEYAQAGMDGVTAKPIELS
RLVEQMNVALSGRRSGPVTGATAAA

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=376, Percent_Identity=35.9042553191489, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788713, Length=378, Percent_Identity=34.3915343915344, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI87081816, Length=377, Percent_Identity=34.2175066312997, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=41.2451361867704, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI145693157, Length=327, Percent_Identity=34.2507645259939, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=33.75, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=29.6943231441048, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=31.3008130081301, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=28.936170212766, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=30.0847457627119, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=32.0512820512821, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=27.34375, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=29.1845493562232, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=28.2608695652174, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=28.310502283105, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=31.9327731092437, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=138, Percent_Identity=35.5072463768116, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322000, Length=109, Percent_Identity=33.9449541284404, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323034, Length=74, Percent_Identity=40.5405405405405, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62473; Mature: 62342

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSFSYHRLASTRARELPMRVGLALIIGAGTLYLTQSPWTFAWLAAVAATQLLDLRLTA
CCCCCCHHHHHHHHHHHCHHHHHHEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHCCC
PMRRDPDFVPDRAQERVYLASVTLNVLVYSAITPLCWLKGGLEGHLYALLVPAAGLINVA
CCCCCCCCCCCCHHCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHH
LQAQSAPKMLWAGCTPHALYLVSLPVLSILVEQDADVAGMAFVAVGASLYLAHLFIAVLR
HHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NRQAAVALDEALGEAQAARARAQEASAAKSEFLATMSHEIRTPLNGVLGMAQAMAHDPLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
RRQRERLEVIRQSGEVLLVLLNDLLDISKIEAAKLELDLAPLDLHDLAAQAQEAFAPLAA
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHCC
SKDLELSVRAAPELAGAWRADATRVRQILYNLLANAVKFTERGAVAADLFLDAAGQVVLR
CCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEE
VRDTGPGVAPERLDALFERFVQAEASTTRRYGGSGLGLAISRDLARLMGGDIAAQSTPGA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
GSTFTVILPLDRADAPEVVGPAAAPAEVAAIRVLVAEDNETNQLVLKTLLGQLGVEVEMT
CCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEE
ADGHEAVEAWRQGPFDLILMDVQMPVMDGLAATRRIREIEAQTGRARTPIVALTANAMSH
CCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
HLVEYAQAGMDGVTAKPIELSRLVEQMNVALSGRRSGPVTGATAAA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPSFSYHRLASTRARELPMRVGLALIIGAGTLYLTQSPWTFAWLAAVAATQLLDLRLTA
CCCCCHHHHHHHHHHHCHHHHHHEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHCCC
PMRRDPDFVPDRAQERVYLASVTLNVLVYSAITPLCWLKGGLEGHLYALLVPAAGLINVA
CCCCCCCCCCCCHHCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHH
LQAQSAPKMLWAGCTPHALYLVSLPVLSILVEQDADVAGMAFVAVGASLYLAHLFIAVLR
HHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NRQAAVALDEALGEAQAARARAQEASAAKSEFLATMSHEIRTPLNGVLGMAQAMAHDPLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
RRQRERLEVIRQSGEVLLVLLNDLLDISKIEAAKLELDLAPLDLHDLAAQAQEAFAPLAA
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHCC
SKDLELSVRAAPELAGAWRADATRVRQILYNLLANAVKFTERGAVAADLFLDAAGQVVLR
CCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEE
VRDTGPGVAPERLDALFERFVQAEASTTRRYGGSGLGLAISRDLARLMGGDIAAQSTPGA
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
GSTFTVILPLDRADAPEVVGPAAAPAEVAAIRVLVAEDNETNQLVLKTLLGQLGVEVEMT
CCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCEEEEE
ADGHEAVEAWRQGPFDLILMDVQMPVMDGLAATRRIREIEAQTGRARTPIVALTANAMSH
CCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
HLVEYAQAGMDGVTAKPIELSRLVEQMNVALSGRRSGPVTGATAAA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]