Click here to switch to the map view.

The map label for this gene is murI

Identifier: 197103587

GI number: 197103587

Start: 111774

End: 112625

Strand: Direct

Name: murI

Synonym: PHZ_c0121

Alternate gene names: 197103587

Gene position: 111774-112625 (Clockwise)

Preceding gene: 197103585

Following gene: 197103589

Centisome position: 2.8

GC content: 72.42

Gene sequence:

>852_bases
ATGGCCATTGGTGTCTTCGACTCCGGCGTGGGCGGCCTGACCGTCCACCACAGGCTCGTGGAGCGCTTCCCCGACGCCGA
CTTCGTCTATCTCGCCGACCAGGCGAACGCGCCGTACGGCGGCCGCCCCGGCGAGGAGATCGTCGAGCTGACCAAGGCGG
GCTGCATCCGGCTGTTCGAGGCGGGCTGCGACCTCGTCGTGCTGGCCTGCAACACCGCCGCCAGCGTGGCCCTGCGCCGC
CTGCAGCAGACCTGGCTGCCGGGCTACCGCCGCGAGACGGGGCGGGCGCTGAACGTGCTGGGCATCGTCGTGCCGACCAT
CGAGGCGGCCACGGGCCTGCCGTGGGAGCACGAGGCCGAGCGGCGCGGCGAGAAGGTCGAGAAGCTCGACATCCTCGGCG
TCTTCTCCACCCCCGCCACCGCCCGCAGCCGGGTCTACGAGATCGAGATCGACAAGCGCCGGCAGGACGTGGCGGTCTTT
TCCGAGCCCTGCCCCGAGCTCGCCCGGATGATCGAGGCCGGCGCCCCGCGCGAGGAGCTGAAGGCGGTGATCGAGGGCCA
CGTCCAGGCGCTGAGGACCCGTATCGGCCGCGCGCCGGATCGCGCGATCCTCGGCTGCACCCATTACGAGATCGTCGCCG
ACCTGTTTCGCGAGGCGCTGCCGCCCGGAACCCCGCTGATCCGCCAGCCCGAGGCGACCGCCGACGCCCTGGCGCGCTAC
CTCGACCGGCATCCGGAGTTCGATCCCGGCCGTTCGGGCCTGCGGCGGTTCCTGACCACGGGCGAGCCCGGCGCCCAGAA
CAGCCTGGTCGAGACCTTCTGGGGCGGCCCGCTAAGCTTCGAGCCCGCCTGA

Upstream 100 bases:

>100_bases
GGCCTTGATATGACGCCGGTTTTCCCGCGGGCTCGCCCGGCGAGGCGCGGGCCGCACGACGGCCTAGCCGCCGGTCGGGA
CGCAGTTTAAGCAACCGGAC

Downstream 100 bases:

>100_bases
AGGGGAGGAGTCCCCCCATGAGCACCCGCGTCAGACCCGTCATGCTCGCCGGCGCCATGATCGCCGCAGCCTTCGCCGGC
GCGGCCCGGGCCGAGGTGGT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAIGVFDSGVGGLTVHHRLVERFPDADFVYLADQANAPYGGRPGEEIVELTKAGCIRLFEAGCDLVVLACNTAASVALRR
LQQTWLPGYRRETGRALNVLGIVVPTIEAATGLPWEHEAERRGEKVEKLDILGVFSTPATARSRVYEIEIDKRRQDVAVF
SEPCPELARMIEAGAPREELKAVIEGHVQALRTRIGRAPDRAILGCTHYEIVADLFREALPPGTPLIRQPEATADALARY
LDRHPEFDPGRSGLRRFLTTGEPGAQNSLVETFWGGPLSFEPA

Sequences:

>Translated_283_residues
MAIGVFDSGVGGLTVHHRLVERFPDADFVYLADQANAPYGGRPGEEIVELTKAGCIRLFEAGCDLVVLACNTAASVALRR
LQQTWLPGYRRETGRALNVLGIVVPTIEAATGLPWEHEAERRGEKVEKLDILGVFSTPATARSRVYEIEIDKRRQDVAVF
SEPCPELARMIEAGAPREELKAVIEGHVQALRTRIGRAPDRAILGCTHYEIVADLFREALPPGTPLIRQPEATADALARY
LDRHPEFDPGRSGLRRFLTTGEPGAQNSLVETFWGGPLSFEPA
>Mature_282_residues
AIGVFDSGVGGLTVHHRLVERFPDADFVYLADQANAPYGGRPGEEIVELTKAGCIRLFEAGCDLVVLACNTAASVALRRL
QQTWLPGYRRETGRALNVLGIVVPTIEAATGLPWEHEAERRGEKVEKLDILGVFSTPATARSRVYEIEIDKRRQDVAVFS
EPCPELARMIEAGAPREELKAVIEGHVQALRTRIGRAPDRAILGCTHYEIVADLFREALPPGTPLIRQPEATADALARYL
DRHPEFDPGRSGLRRFLTTGEPGAQNSLVETFWGGPLSFEPA

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=275, Percent_Identity=28.3636363636364, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_PHEZH (B4RCD6)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002128964.1
- GeneID:   6789609
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c0121
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   CLSK891657
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 31046; Mature: 30915

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGVFDSGVGGLTVHHRLVERFPDADFVYLADQANAPYGGRPGEEIVELTKAGCIRLFE
CEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
AGCDLVVLACNTAASVALRRLQQTWLPGYRRETGRALNVLGIVVPTIEAATGLPWEHEAE
CCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHH
RRGEKVEKLDILGVFSTPATARSRVYEIEIDKRRQDVAVFSEPCPELARMIEAGAPREEL
HCCCHHHHHEEEEEECCCCHHHHEEEEEEECCCHHHHHHHHCCCHHHHHHHHCCCCHHHH
KAVIEGHVQALRTRIGRAPDRAILGCTHYEIVADLFREALPPGTPLIRQPEATADALARY
HHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LDRHPEFDPGRSGLRRFLTTGEPGAQNSLVETFWGGPLSFEPA
HHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AIGVFDSGVGGLTVHHRLVERFPDADFVYLADQANAPYGGRPGEEIVELTKAGCIRLFE
EEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
AGCDLVVLACNTAASVALRRLQQTWLPGYRRETGRALNVLGIVVPTIEAATGLPWEHEAE
CCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHH
RRGEKVEKLDILGVFSTPATARSRVYEIEIDKRRQDVAVFSEPCPELARMIEAGAPREEL
HCCCHHHHHEEEEEECCCCHHHHEEEEEEECCCHHHHHHHHCCCHHHHHHHHCCCCHHHH
KAVIEGHVQALRTRIGRAPDRAILGCTHYEIVADLFREALPPGTPLIRQPEATADALARY
HHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LDRHPEFDPGRSGLRRFLTTGEPGAQNSLVETFWGGPLSFEPA
HHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA