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The map label for this gene is dcp [H]

Identifier: 197103586

GI number: 197103586

Start: 109448

End: 111604

Strand: Reverse

Name: dcp [H]

Synonym: PHZ_c0120

Alternate gene names: 197103586

Gene position: 111604-109448 (Counterclockwise)

Preceding gene: 197103588

Following gene: 197103583

Centisome position: 2.79

GC content: 69.36

Gene sequence:

>2157_bases
ATGCGCCGTCGCACCTTCCTCGCCGCCACCTCGGCCCTCGCCGCCACCTCGGCCCTCGCCGCCGCCGCCGCCCTGCCCGC
CGCCGTCCTGGCCCAGGACCTTCCCAAGGACTTGGCCGCCAACCCGGCCGCGGCCCCGTGGACTGGGCCCTTCGGCGGCG
TGCCCGCCTTCGACAAGGTGCGGCTGGAGCACTTCCGTCCCGCGCTGGAGGCCGGCATGGCGCAGGAGTGGGCCGAGGTG
GAGGCGATCGCGAACGATCCCGCCCCGCCCACCTTCGACAACACCATCGAGGCCCTGGAGCGTAGCGGCTCTGCCCTCGA
CCGCGTCCAGACGATCTACGGCGTCTGGGTGGCGACCCTGTCCACGCCCGAGCTGCGCGCGCTCGACAAGGAGATGCAGC
CGAAGCTCGCGGCCCATAGCGACCGCATCCTGCAGAACGAGAAGCTCTTCCAGCGCATCGACGCGGTCTACCGCCAGCGC
GAGAGCCTGAAGCTCACCCCCGAGCAGGACCGGCTGCTGTGGCTGCGCTGGAACACCTTCGTCCGCAACGGCGCCCAGCT
CGCCCCCGAGGCCAAGGCCAGGGTCGCGGCGATCAACGCCGAGTTGGCCACGGCCTTCACCGCCTTCAGCCAGAACCTGC
TGCACGACGAGAACGAGTACGACCTCTACCTGAAGGAGGCCGACCTCGCCGGCCTGCCCGCCGACGTGCGCGCGGCCATG
GCCGCGGCGGCCAAGGCCAAGGGCCGCGACGGCGAGTACGTGATCGTCAACACGCGCTCGTCGGTGGACCCGTTCCTCAC
CTACGCCGAGCGCCGCGACCTGCGCGAGAAGGTCTGGCGCACCTACTACAGCCGCGGCGACAACGGCGGAGCTCACGACA
ACAACGGCCTGATCCGCCAGATCCTGAAGCTGCGCGCCGAGCGGGCGAAGCTGTTCGGCTATCCGACCCACGCCCACTGG
CGGCTGGCCAACAACTCCATGGCCGAGACCCCGCAGGCCGCCAGCGAGCTGATGGAGCGGGTGTGGCCCTTCGCCGTCGC
CCGCGTGAAGGAGGAGGTGGCCGAGATGCAGGCCATCGCCGACAAGGAAGGCGCCGGGATCAAGATCGAGCCCTGGGACT
ACCGGTTCTACGCCGAGAAGGTCCGCAAGGCCCGCTACGACCTCGATATGAACGAGGTGAAGCCTTACCTGCAGCTCGAG
AAGCTGCGCGAGGGCATGTTCTGGGCCGCCGGCCAGCTCTACGGCTTCACGTTCCATCCGGTGACGAACGTGCCCGTGCA
GCATCCGGACGTCCGCGTCTGGGAGGTGAAGCGCGGGGCCGAGCACATCGGCCTGTGGTACTTCGATCCCTACGCCCGGA
CCGGCAAGCGCTCGGGCGCCTGGATGAACGCCTACCGGGCGCAGGAGACCTTCGACGGCAAGGTCACCACCATCGTCTCG
AACAACTCGAACTTCGTGAAGGGCGCCCCCGGCGAGGCGGTGCTGATCTCGTGGGACGACGCCGAGACCATGTTCCACGA
GTTCGGCCACGCCCTGCACGGCCTCAACTCGGCGGTGACCTATCCCTCCGTGTCGGGCACCCGGGTGTTCCGCGACTACG
TGGAGTTCCCCTCGACGGTGAACGAGTCCTGGCTGCGCACGCCCCAGGTGCTGAACCGGTTCGCCCTGCATCATCAGACC
GGCAAGCCGATCCCGCCCGAGCTGGTCGCCAAGATCGAGAACGCCTCGACCTTCCGCCAGGGCTTCGACGTCACCGAATT
CCTCGCCTCGGCGCTGATCGACATGAAGCTGCACCTGGCCGGCGACGCCGACATCGATCCCGACGCCTTCGAGCGCGAGG
AGCTGGCGAAACTCGGCATGCCCGCCGAGCTGCCGATGCGCCACCGCACGCCGCAGTTCGGGCACATCTTCGCGTCCGAC
GGCTATTCGGCCGGCTACTACTCGTACCTGTGGGCCGAGGTGATCGCGCTGGACGCCGTCGAGGCGTTCCGCGAGGCGCC
GGGCGGCCTCTACGACAAGGGCGTCGCCAAGCGGCTGCACGACCACGTCATGAGCGTCGGCAACTCGGTCCACCCGCGCG
AGGGCTACCGCGCCTTCCGCGGCCGCGACCCCGACGTGAAGGCCTACCTGAAGGACAAGGGCTTCCCGACGAGCTGA

Upstream 100 bases:

>100_bases
CCCGCGGGAAAACCGGCGTCATATCAAGGCCCTGTCACGTGACGTTCAGCTCCGATCCTGCTTAAGGTCGCAGGCAATGA
GCCGTCCGACCGGAGATTCC

Downstream 100 bases:

>100_bases
CCCTCAGGCGAACAGGTCGCCCTGGGGAGTCTCCTTCGGGATGGCCGCCTTCGCGCCCTCGATGGCGAGCAGCCTCAGCT
TGGTGTCCACCCCGCCGCGG

Product: peptidyl-dipeptidase DCP

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MRRRTFLAATSALAATSALAAAAALPAAVLAQDLPKDLAANPAAAPWTGPFGGVPAFDKVRLEHFRPALEAGMAQEWAEV
EAIANDPAPPTFDNTIEALERSGSALDRVQTIYGVWVATLSTPELRALDKEMQPKLAAHSDRILQNEKLFQRIDAVYRQR
ESLKLTPEQDRLLWLRWNTFVRNGAQLAPEAKARVAAINAELATAFTAFSQNLLHDENEYDLYLKEADLAGLPADVRAAM
AAAAKAKGRDGEYVIVNTRSSVDPFLTYAERRDLREKVWRTYYSRGDNGGAHDNNGLIRQILKLRAERAKLFGYPTHAHW
RLANNSMAETPQAASELMERVWPFAVARVKEEVAEMQAIADKEGAGIKIEPWDYRFYAEKVRKARYDLDMNEVKPYLQLE
KLREGMFWAAGQLYGFTFHPVTNVPVQHPDVRVWEVKRGAEHIGLWYFDPYARTGKRSGAWMNAYRAQETFDGKVTTIVS
NNSNFVKGAPGEAVLISWDDAETMFHEFGHALHGLNSAVTYPSVSGTRVFRDYVEFPSTVNESWLRTPQVLNRFALHHQT
GKPIPPELVAKIENASTFRQGFDVTEFLASALIDMKLHLAGDADIDPDAFEREELAKLGMPAELPMRHRTPQFGHIFASD
GYSAGYYSYLWAEVIALDAVEAFREAPGGLYDKGVAKRLHDHVMSVGNSVHPREGYRAFRGRDPDVKAYLKDKGFPTS

Sequences:

>Translated_718_residues
MRRRTFLAATSALAATSALAAAAALPAAVLAQDLPKDLAANPAAAPWTGPFGGVPAFDKVRLEHFRPALEAGMAQEWAEV
EAIANDPAPPTFDNTIEALERSGSALDRVQTIYGVWVATLSTPELRALDKEMQPKLAAHSDRILQNEKLFQRIDAVYRQR
ESLKLTPEQDRLLWLRWNTFVRNGAQLAPEAKARVAAINAELATAFTAFSQNLLHDENEYDLYLKEADLAGLPADVRAAM
AAAAKAKGRDGEYVIVNTRSSVDPFLTYAERRDLREKVWRTYYSRGDNGGAHDNNGLIRQILKLRAERAKLFGYPTHAHW
RLANNSMAETPQAASELMERVWPFAVARVKEEVAEMQAIADKEGAGIKIEPWDYRFYAEKVRKARYDLDMNEVKPYLQLE
KLREGMFWAAGQLYGFTFHPVTNVPVQHPDVRVWEVKRGAEHIGLWYFDPYARTGKRSGAWMNAYRAQETFDGKVTTIVS
NNSNFVKGAPGEAVLISWDDAETMFHEFGHALHGLNSAVTYPSVSGTRVFRDYVEFPSTVNESWLRTPQVLNRFALHHQT
GKPIPPELVAKIENASTFRQGFDVTEFLASALIDMKLHLAGDADIDPDAFEREELAKLGMPAELPMRHRTPQFGHIFASD
GYSAGYYSYLWAEVIALDAVEAFREAPGGLYDKGVAKRLHDHVMSVGNSVHPREGYRAFRGRDPDVKAYLKDKGFPTS
>Mature_718_residues
MRRRTFLAATSALAATSALAAAAALPAAVLAQDLPKDLAANPAAAPWTGPFGGVPAFDKVRLEHFRPALEAGMAQEWAEV
EAIANDPAPPTFDNTIEALERSGSALDRVQTIYGVWVATLSTPELRALDKEMQPKLAAHSDRILQNEKLFQRIDAVYRQR
ESLKLTPEQDRLLWLRWNTFVRNGAQLAPEAKARVAAINAELATAFTAFSQNLLHDENEYDLYLKEADLAGLPADVRAAM
AAAAKAKGRDGEYVIVNTRSSVDPFLTYAERRDLREKVWRTYYSRGDNGGAHDNNGLIRQILKLRAERAKLFGYPTHAHW
RLANNSMAETPQAASELMERVWPFAVARVKEEVAEMQAIADKEGAGIKIEPWDYRFYAEKVRKARYDLDMNEVKPYLQLE
KLREGMFWAAGQLYGFTFHPVTNVPVQHPDVRVWEVKRGAEHIGLWYFDPYARTGKRSGAWMNAYRAQETFDGKVTTIVS
NNSNFVKGAPGEAVLISWDDAETMFHEFGHALHGLNSAVTYPSVSGTRVFRDYVEFPSTVNESWLRTPQVLNRFALHHQT
GKPIPPELVAKIENASTFRQGFDVTEFLASALIDMKLHLAGDADIDPDAFEREELAKLGMPAELPMRHRTPQFGHIFASD
GYSAGYYSYLWAEVIALDAVEAFREAPGGLYDKGVAKRLHDHVMSVGNSVHPREGYRAFRGRDPDVKAYLKDKGFPTS

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=635, Percent_Identity=28.9763779527559, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI14149738, Length=639, Percent_Identity=25.1956181533646, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI156105687, Length=648, Percent_Identity=22.5308641975309, Blast_Score=129, Evalue=1e-29,
Organism=Escherichia coli, GI1787819, Length=682, Percent_Identity=39.7360703812317, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1789913, Length=685, Percent_Identity=31.970802919708, Blast_Score=300, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI32565901, Length=568, Percent_Identity=22.7112676056338, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71999758, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319793, Length=615, Percent_Identity=25.5284552845528, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322715, Length=522, Percent_Identity=20.6896551724138, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356111, Length=491, Percent_Identity=25.6619144602851, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI20129717, Length=415, Percent_Identity=25.7831325301205, Blast_Score=101, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 80352; Mature: 80352

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRTFLAATSALAATSALAAAAALPAAVLAQDLPKDLAANPAAAPWTGPFGGVPAFDKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHH
RLEHFRPALEAGMAQEWAEVEAIANDPAPPTFDNTIEALERSGSALDRVQTIYGVWVATL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHC
STPELRALDKEMQPKLAAHSDRILQNEKLFQRIDAVYRQRESLKLTPEQDRLLWLRWNTF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHH
VRNGAQLAPEAKARVAAINAELATAFTAFSQNLLHDENEYDLYLKEADLAGLPADVRAAM
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHH
AAAAKAKGRDGEYVIVNTRSSVDPFLTYAERRDLREKVWRTYYSRGDNGGAHDNNGLIRQ
HHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
ILKLRAERAKLFGYPTHAHWRLANNSMAETPQAASELMERVWPFAVARVKEEVAEMQAIA
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKEGAGIKIEPWDYRFYAEKVRKARYDLDMNEVKPYLQLEKLREGMFWAAGQLYGFTFHP
CCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEECCCEEEEEECC
VTNVPVQHPDVRVWEVKRGAEHIGLWYFDPYARTGKRSGAWMNAYRAQETFDGKVTTIVS
CCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHCCCCEEEEEEE
NNSNFVKGAPGEAVLISWDDAETMFHEFGHALHGLNSAVTYPSVSGTRVFRDYVEFPSTV
CCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCC
NESWLRTPQVLNRFALHHQTGKPIPPELVAKIENASTFRQGFDVTEFLASALIDMKLHLA
CHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEC
GDADIDPDAFEREELAKLGMPAELPMRHRTPQFGHIFASDGYSAGYYSYLWAEVIALDAV
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
EAFREAPGGLYDKGVAKRLHDHVMSVGNSVHPREGYRAFRGRDPDVKAYLKDKGFPTS
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHEECCCCCCC
>Mature Secondary Structure
MRRRTFLAATSALAATSALAAAAALPAAVLAQDLPKDLAANPAAAPWTGPFGGVPAFDKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCHHHH
RLEHFRPALEAGMAQEWAEVEAIANDPAPPTFDNTIEALERSGSALDRVQTIYGVWVATL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHC
STPELRALDKEMQPKLAAHSDRILQNEKLFQRIDAVYRQRESLKLTPEQDRLLWLRWNTF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHH
VRNGAQLAPEAKARVAAINAELATAFTAFSQNLLHDENEYDLYLKEADLAGLPADVRAAM
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHH
AAAAKAKGRDGEYVIVNTRSSVDPFLTYAERRDLREKVWRTYYSRGDNGGAHDNNGLIRQ
HHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
ILKLRAERAKLFGYPTHAHWRLANNSMAETPQAASELMERVWPFAVARVKEEVAEMQAIA
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKEGAGIKIEPWDYRFYAEKVRKARYDLDMNEVKPYLQLEKLREGMFWAAGQLYGFTFHP
CCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEECCCEEEEEECC
VTNVPVQHPDVRVWEVKRGAEHIGLWYFDPYARTGKRSGAWMNAYRAQETFDGKVTTIVS
CCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHCCCCEEEEEEE
NNSNFVKGAPGEAVLISWDDAETMFHEFGHALHGLNSAVTYPSVSGTRVFRDYVEFPSTV
CCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCC
NESWLRTPQVLNRFALHHQTGKPIPPELVAKIENASTFRQGFDVTEFLASALIDMKLHLA
CHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEC
GDADIDPDAFEREELAKLGMPAELPMRHRTPQFGHIFASDGYSAGYYSYLWAEVIALDAV
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
EAFREAPGGLYDKGVAKRLHDHVMSVGNSVHPREGYRAFRGRDPDVKAYLKDKGFPTS
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]