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The map label for this gene is ffh [H]

Identifier: 197103583

GI number: 197103583

Start: 106420

End: 107946

Strand: Reverse

Name: ffh [H]

Synonym: PHZ_c0117

Alternate gene names: 197103583

Gene position: 107946-106420 (Counterclockwise)

Preceding gene: 197103586

Following gene: 197103582

Centisome position: 2.7

GC content: 70.07

Gene sequence:

>1527_bases
TTGCACTTGTTCGACGCGCTTTCTGATCGGCTGACATCCGTCTTCGACCGGCTCTCCGGTCGCGGCGTGCTGTCCGAGAA
GGACATCGACGAGGCGATGCGCGAGGTGCGCGTCGCCCTGCTCGAGGCCGACGTCGCCCTGCCGGTCGTCCGGCAGTTCA
TCGACAAGGCCAAGGAGCGCGCGACGGGCGAGGCGGTGATCCGCTCGGTCAAGCCCGCCGACCAGGTCATCAAGATCACC
TACGACGGCCTCGTCGAGATGCTGGGCGGAGACGGCGAGCCCGAGGGCCTGCGCCTGTCGGCCAACCCGCCGACCGTGAT
CCTGATGAGCGGCCTGCAGGGGTCGGGCAAGACGACCACCGCCGGCAAGCTCGCCCTGCGCCTCTCAAAGGAGCGCAAGA
AGGTCCTCCTGGCCTCGCTCGACACCCGCCGCCCGGCGGCCATGGAGCAGCTGGCCATGCTGGCGACCCAGGCCGGGGTG
GACTCGCTGCCGATCGTGCCGGGCCAGTCGGCGCCGGACATCACCCGCCGCGCGCTGCAGGCGGCCAGGCTGCAGGGCTA
CGACGTCCTGATCCTCGACACCGCCGGCCGCACGACGCTGGACGAGGCGATGATGAGCGAGGCGGCCGAGATCGCGAAGA
TCTCGAACCCCTCCGAGACCCTGCTCGTCGCCGACGCCCTGACTGGCCAGGACGCGGTGCGCACCGCCAAGGCCTTCCAC
GAGCGCCTGCCGCTCACCGGCTTGGTGCTCACCCGCGCCGATGGCGACGGCCGCGGCGGCGCGGCCCTGTCGATGCGCGC
GGTCACCGGCCTGCCGATCAAGTTCCTCGGCGTGTCCGAGAAGATCGACGGCCTCGACGCCTTCGACGCCCACCGCGTGG
CCGGCCGCATCCTGGGCCGCGGCGACGTCGTGGCCCTTGTCGAGAAGGCCGCCCAGGACCTCGACGTCGAGCGCGCCGAG
GCGATGGCCAAGAAGCTGGCCAAGGGCCAGTTCGACCTCGACCTGATGGCCGAGCAGCTCAAGCAGATGAAGCGCATGGG
CGGCATGGAAGGCCTGATGGGCCTGCTGCCCGGCGTGCAGAAGATGAAGAAGCAGATCGCCGAGAGCGGGGTCAGCGACA
AGACCTTCGACCGCCAGCTCGCGATCATCTCGTCCATGACCAAGGCCGAGCGGAAGAAGCCCGACATCCTGCAGGCTTCG
CGCAAGCGCCGGATCGCCGCGGGCGCCGGCGTCGACGTGGCCGAGATCAACCGCCTGCTCAAGCAGCACCGCCAGATGGC
CGACGCCTTCAAGGCGCTGTCCAAGAACGGCGGCAAGGGCTTCGGCCAGATGGCCAAGATGCTCGGCGGCGGCGACATGG
ACCTGGGCAAGCTGGCCCAGCTCGGCGGCGGCAAGGCGCCGACGCCCGAGCAGATGGAAGAGCTCCAGAAACAACTCGGC
GCCGGCCCCAAGGGGGCCCTGGGCGGCCTGAAGCTTCCCGGCCTCGGCGGCGGCCTGCCGCCGGGCTTCAATCCCTTCAA
GAAATAA

Upstream 100 bases:

>100_bases
CTCCACCGCCACGACCCCCACCACCATATGGGACGAGGGCGGCGAGGCCCCCCGTCGACGCAATCGTCCACGGGGGCTGA
TCGCGTTTGGGCCATAGGAG

Downstream 100 bases:

>100_bases
GACCTGAGGACCTAGACCAATGCTGAAGATCCGTCTCGCCCGCGGCGGCGCCAAGAAGCGCCCCTACTACTCGATCGTCA
TCGCCGACAGCCACTCGCCC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MHLFDALSDRLTSVFDRLSGRGVLSEKDIDEAMREVRVALLEADVALPVVRQFIDKAKERATGEAVIRSVKPADQVIKIT
YDGLVEMLGGDGEPEGLRLSANPPTVILMSGLQGSGKTTTAGKLALRLSKERKKVLLASLDTRRPAAMEQLAMLATQAGV
DSLPIVPGQSAPDITRRALQAARLQGYDVLILDTAGRTTLDEAMMSEAAEIAKISNPSETLLVADALTGQDAVRTAKAFH
ERLPLTGLVLTRADGDGRGGAALSMRAVTGLPIKFLGVSEKIDGLDAFDAHRVAGRILGRGDVVALVEKAAQDLDVERAE
AMAKKLAKGQFDLDLMAEQLKQMKRMGGMEGLMGLLPGVQKMKKQIAESGVSDKTFDRQLAIISSMTKAERKKPDILQAS
RKRRIAAGAGVDVAEINRLLKQHRQMADAFKALSKNGGKGFGQMAKMLGGGDMDLGKLAQLGGGKAPTPEQMEELQKQLG
AGPKGALGGLKLPGLGGGLPPGFNPFKK

Sequences:

>Translated_508_residues
MHLFDALSDRLTSVFDRLSGRGVLSEKDIDEAMREVRVALLEADVALPVVRQFIDKAKERATGEAVIRSVKPADQVIKIT
YDGLVEMLGGDGEPEGLRLSANPPTVILMSGLQGSGKTTTAGKLALRLSKERKKVLLASLDTRRPAAMEQLAMLATQAGV
DSLPIVPGQSAPDITRRALQAARLQGYDVLILDTAGRTTLDEAMMSEAAEIAKISNPSETLLVADALTGQDAVRTAKAFH
ERLPLTGLVLTRADGDGRGGAALSMRAVTGLPIKFLGVSEKIDGLDAFDAHRVAGRILGRGDVVALVEKAAQDLDVERAE
AMAKKLAKGQFDLDLMAEQLKQMKRMGGMEGLMGLLPGVQKMKKQIAESGVSDKTFDRQLAIISSMTKAERKKPDILQAS
RKRRIAAGAGVDVAEINRLLKQHRQMADAFKALSKNGGKGFGQMAKMLGGGDMDLGKLAQLGGGKAPTPEQMEELQKQLG
AGPKGALGGLKLPGLGGGLPPGFNPFKK
>Mature_508_residues
MHLFDALSDRLTSVFDRLSGRGVLSEKDIDEAMREVRVALLEADVALPVVRQFIDKAKERATGEAVIRSVKPADQVIKIT
YDGLVEMLGGDGEPEGLRLSANPPTVILMSGLQGSGKTTTAGKLALRLSKERKKVLLASLDTRRPAAMEQLAMLATQAGV
DSLPIVPGQSAPDITRRALQAARLQGYDVLILDTAGRTTLDEAMMSEAAEIAKISNPSETLLVADALTGQDAVRTAKAFH
ERLPLTGLVLTRADGDGRGGAALSMRAVTGLPIKFLGVSEKIDGLDAFDAHRVAGRILGRGDVVALVEKAAQDLDVERAE
AMAKKLAKGQFDLDLMAEQLKQMKRMGGMEGLMGLLPGVQKMKKQIAESGVSDKTFDRQLAIISSMTKAERKKPDILQAS
RKRRIAAGAGVDVAEINRLLKQHRQMADAFKALSKNGGKGFGQMAKMLGGGDMDLGKLAQLGGGKAPTPEQMEELQKQLG
AGPKGALGGLKLPGLGGGLPPGFNPFKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=481, Percent_Identity=28.8981288981289, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI226371618, Length=383, Percent_Identity=30.5483028720627, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI23308697, Length=310, Percent_Identity=27.0967741935484, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI295424842, Length=310, Percent_Identity=27.0967741935484, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI89061728, Length=156, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788963, Length=426, Percent_Identity=53.7558685446009, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1789874, Length=269, Percent_Identity=35.6877323420074, Blast_Score=146, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=502, Percent_Identity=26.6932270916335, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI193206261, Length=312, Percent_Identity=27.8846153846154, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325345, Length=472, Percent_Identity=29.4491525423729, Blast_Score=200, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6320498, Length=211, Percent_Identity=29.8578199052133, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17647949, Length=492, Percent_Identity=28.2520325203252, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24641198, Length=317, Percent_Identity=28.0757097791798, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53919; Mature: 53919

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLFDALSDRLTSVFDRLSGRGVLSEKDIDEAMREVRVALLEADVALPVVRQFIDKAKER
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGEAVIRSVKPADQVIKITYDGLVEMLGGDGEPEGLRLSANPPTVILMSGLQGSGKTTT
CHHHHHHHHCCCHHHEEEEHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCCH
AGKLALRLSKERKKVLLASLDTRRPAAMEQLAMLATQAGVDSLPIVPGQSAPDITRRALQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
AARLQGYDVLILDTAGRTTLDEAMMSEAAEIAKISNPSETLLVADALTGQDAVRTAKAFH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHH
ERLPLTGLVLTRADGDGRGGAALSMRAVTGLPIKFLGVSEKIDGLDAFDAHRVAGRILGR
HHCCCCEEEEEECCCCCCCCCEEEEHHHCCCCEEEECCCHHCCCCCHHHHHHHHHHHCCC
GDVVALVEKAAQDLDVERAEAMAKKLAKGQFDLDLMAEQLKQMKRMGGMEGLMGLLPGVQ
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KMKKQIAESGVSDKTFDRQLAIISSMTKAERKKPDILQASRKRRIAAGAGVDVAEINRLL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
KQHRQMADAFKALSKNGGKGFGQMAKMLGGGDMDLGKLAQLGGGKAPTPEQMEELQKQLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHC
AGPKGALGGLKLPGLGGGLPPGFNPFKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHLFDALSDRLTSVFDRLSGRGVLSEKDIDEAMREVRVALLEADVALPVVRQFIDKAKER
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGEAVIRSVKPADQVIKITYDGLVEMLGGDGEPEGLRLSANPPTVILMSGLQGSGKTTT
CHHHHHHHHCCCHHHEEEEHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCCH
AGKLALRLSKERKKVLLASLDTRRPAAMEQLAMLATQAGVDSLPIVPGQSAPDITRRALQ
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
AARLQGYDVLILDTAGRTTLDEAMMSEAAEIAKISNPSETLLVADALTGQDAVRTAKAFH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHH
ERLPLTGLVLTRADGDGRGGAALSMRAVTGLPIKFLGVSEKIDGLDAFDAHRVAGRILGR
HHCCCCEEEEEECCCCCCCCCEEEEHHHCCCCEEEECCCHHCCCCCHHHHHHHHHHHCCC
GDVVALVEKAAQDLDVERAEAMAKKLAKGQFDLDLMAEQLKQMKRMGGMEGLMGLLPGVQ
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KMKKQIAESGVSDKTFDRQLAIISSMTKAERKKPDILQASRKRRIAAGAGVDVAEINRLL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
KQHRQMADAFKALSKNGGKGFGQMAKMLGGGDMDLGKLAQLGGGKAPTPEQMEELQKQLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHC
AGPKGALGGLKLPGLGGGLPPGFNPFKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]