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The map label for this gene is aceE [H]

Identifier: 197103539

GI number: 197103539

Start: 68654

End: 71023

Strand: Reverse

Name: aceE [H]

Synonym: PHZ_c0073

Alternate gene names: 197103539

Gene position: 71023-68654 (Counterclockwise)

Preceding gene: 197103541

Following gene: 197103533

Centisome position: 1.78

GC content: 72.87

Gene sequence:

>2370_bases
ATGCCCCGCGCCCAAGCCGTTCCCGCCGCCGGTCACAACATCGGGACCGCAGACCGGACCCGCGCCCTGACGCGCATCGA
CGAGCGCCTGCGCTGGCTGGCCACCTGGACCATCCACCACGCCAACCACCTGCGCGAGAGCCGCGACGGCCTGAAGGTGG
GCGGCCACCAGGCCTCCTGCGCCTCGATGACCACCATCCTGACGGCGCTGTACTTCCACGCGCTGCGCCCCGAGGACCGG
GTGGCGGTGAAGCCGCACGCCTCCCCGGTCTTCCACGCCGCCCAGTACCTGATGGGCCGGCAGACCCGCGAGCAGCTGGA
GGCCTTCCGCAGCTTCGGCGGCGCCCAGTCCTATCCCTCGCGGACCAAGGACAAGGACGACGTCGACTTCTCCACCGGCT
CGGTCGGCCTGGGCGTGGCGATCACCGCCTTCGCCTCGCTGGCCCAGGATTACCTGAAGGGCCACGGCCTGCTGGATCCG
GCGCGCGAGGGTCGCTTCGTCGCCACGCTGGGCGACGCCGAGCTGGACGAGGGCAACATCTACGAGTGTCTCATCGAGGC
CTACAAGCACGACATCCGCAACGTCTGGTGGATCGTCGACTACAACCGCCAGAGCCTCGACGCGACGACCGCCGACCGGA
TGTTCGACCGGTTCGACGACATCTTCGAGACCGCCGGCTGGCGGGTCGTGACGCTGAAGTGGGGCAAGGCCCAGGAGCGC
GCCTTCGCCCGTCCCGGCGGCGCGGCCCTGCGCAGCTGGATCGAGGCCTGCTCGAACGCCGAATACGCGGCGCTCACCTA
CCAGGGCGGCGCGGCCTGGCGCGCACGCCTGACCCGCGACATCGGCCGCGAGTCGCACGTCCCGGCCCTGCTCGAGAGCT
TCTCGGACGAGGCGCTGCACCAGCTGATGATCGGTCTCGGCGGCCACTGCATCGAGACCCTGACCGAGGCCTTCGACGCC
GCCGCCCGCGACGACACGCCCACCCTGTTCATCGCCTACACGGTCAAGGGCTTCGGCCTGCCGCTGCAGGGCCACAAGGA
CAACCACGCCGGCCTGATGACGCCGTCCCAGGTGGAAGCCCTGCGCGAGGCGATGGGCGTTCCCGCGGGGGCCGAATGGG
AGCCCTACGCCGGCCTGCCGCCCGAGGAGGCCGAGGCGCTGGCGGCCTTCGTGCGCGACGTCCCCTTCGCCGCCGAGGCC
GACCGGCGGCCCCGGGCGGCCCCCGTGCCGGTCCCGCCGCGCGAGGCCTTCCCCGCCCCGGACGGCGCCGAGCAGTCCAC
CCAGGCCGCCTTCGGGCGCATCCTGCTGGACCTCGCCAAGAGCGGCCACCCGATCGCCGACCGGATCGTCACGACCAGCC
CGGACGTGACCGTCTCGACGAACCTCGGCGGCTTCGTGAACCAGCGGGGCCTGTTCCGCCGGCGCGAGACCGCCGACGTG
TTCCGCGACGCCAAGATCCCCTCGCCCCAGAAATGGGCGGGCGGGCGCGCCGGCCAGCACATCGAGCTCGGCATCGCCGA
GCACAACCTGTTCCTGAACCTGGGCGCCCTGGGCCTGACGGCCCCGCTGTTCGGCGAGCGGCTGCTGCCGATCGGGACCG
TGTACGATCCCTTCATCAGCCGCGGCCTCGATGCCCTGAACTACGCCTGCTACCAGGACGCCCGCTTCATGCTGGTGGCG
ACGCCGTCCGGCCTGACGCTGGGCCCGGAAGGCGGGGCGCACCAGTCGATCTACACGCCGCTGATCGGCATCGGCCAGCC
GGGCCTGACCTATTTCGAGCCGGCCTTCGTGGACGAGCTCTCCGAGGTCATGCGCTGGTCGTTCGAGCACATGCAGGCGC
CGGACGGCGGCTCGGTCTACCTGCGCCTGACGACCCGCAGCCTGTCGCAGCCGGAACGGTCCGACGACGCTTGGCGCGAG
CCGGCGCTGAAGGGCGGCTACTGGCTGCGCGAGCCGGCGGAAGGCTCCGAGGCGGCCCTCGTGTTCTGCGGCGCCGTCGC
GCCCGAGGTGCTGGCCGCGGCCGAGCAGCTGGCCGACGACCTGCCGGGGCTGGGCGTGCTGAACGTCGTCTCCCCGGGCC
TGCTGCACCGCGACTGGATGGACGCGCGCCGCGGCCGTTGGACCCGCGGCGAGCGCCGGCGCAGCCACGCCGAGGCGCTG
CTGTCGCGGCTGGCGCCGGGAGCCGGCCTCGTCACCGTCGTCGACGGCTCGCCCGCCACGCTCTCGTGGCTGGGCGGGGT
GCGCGGCATGCGGGTCAGCGCGCTCGGCCTCGACAGCTTCGGCCAGGTCGGCGACCTGCCCGACCTCTACCGCCACTACC
GCCTCGACGTGGACGCCATCGTCGACGCGGCGGCGGAGCTGTTCCTGTAG

Upstream 100 bases:

>100_bases
GCCGCCTGCCCCGGAAACCTGCTAGGAGGGGGTTCGACGTTCCCGAAGCGCCGCCATGGGCGCACGTTCGTCCCCCTCAC
CCCTGACGCCGGAACATTCC

Downstream 100 bases:

>100_bases
TGGGGCTCCCCCTGAAGGGGGAGCGCCGTTACGGAGCCAGCGCCTGCTCCAAGTCTGCGATCAGGTCGTCGGCGGACTCC
ACGCCCACGGACAGGCGGAT

Product: pyruvate dehydrogenase E1 component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 788

Protein sequence:

>789_residues
MPRAQAVPAAGHNIGTADRTRALTRIDERLRWLATWTIHHANHLRESRDGLKVGGHQASCASMTTILTALYFHALRPEDR
VAVKPHASPVFHAAQYLMGRQTREQLEAFRSFGGAQSYPSRTKDKDDVDFSTGSVGLGVAITAFASLAQDYLKGHGLLDP
AREGRFVATLGDAELDEGNIYECLIEAYKHDIRNVWWIVDYNRQSLDATTADRMFDRFDDIFETAGWRVVTLKWGKAQER
AFARPGGAALRSWIEACSNAEYAALTYQGGAAWRARLTRDIGRESHVPALLESFSDEALHQLMIGLGGHCIETLTEAFDA
AARDDTPTLFIAYTVKGFGLPLQGHKDNHAGLMTPSQVEALREAMGVPAGAEWEPYAGLPPEEAEALAAFVRDVPFAAEA
DRRPRAAPVPVPPREAFPAPDGAEQSTQAAFGRILLDLAKSGHPIADRIVTTSPDVTVSTNLGGFVNQRGLFRRRETADV
FRDAKIPSPQKWAGGRAGQHIELGIAEHNLFLNLGALGLTAPLFGERLLPIGTVYDPFISRGLDALNYACYQDARFMLVA
TPSGLTLGPEGGAHQSIYTPLIGIGQPGLTYFEPAFVDELSEVMRWSFEHMQAPDGGSVYLRLTTRSLSQPERSDDAWRE
PALKGGYWLREPAEGSEAALVFCGAVAPEVLAAAEQLADDLPGLGVLNVVSPGLLHRDWMDARRGRWTRGERRRSHAEAL
LSRLAPGAGLVTVVDGSPATLSWLGGVRGMRVSALGLDSFGQVGDLPDLYRHYRLDVDAIVDAAAELFL

Sequences:

>Translated_789_residues
MPRAQAVPAAGHNIGTADRTRALTRIDERLRWLATWTIHHANHLRESRDGLKVGGHQASCASMTTILTALYFHALRPEDR
VAVKPHASPVFHAAQYLMGRQTREQLEAFRSFGGAQSYPSRTKDKDDVDFSTGSVGLGVAITAFASLAQDYLKGHGLLDP
AREGRFVATLGDAELDEGNIYECLIEAYKHDIRNVWWIVDYNRQSLDATTADRMFDRFDDIFETAGWRVVTLKWGKAQER
AFARPGGAALRSWIEACSNAEYAALTYQGGAAWRARLTRDIGRESHVPALLESFSDEALHQLMIGLGGHCIETLTEAFDA
AARDDTPTLFIAYTVKGFGLPLQGHKDNHAGLMTPSQVEALREAMGVPAGAEWEPYAGLPPEEAEALAAFVRDVPFAAEA
DRRPRAAPVPVPPREAFPAPDGAEQSTQAAFGRILLDLAKSGHPIADRIVTTSPDVTVSTNLGGFVNQRGLFRRRETADV
FRDAKIPSPQKWAGGRAGQHIELGIAEHNLFLNLGALGLTAPLFGERLLPIGTVYDPFISRGLDALNYACYQDARFMLVA
TPSGLTLGPEGGAHQSIYTPLIGIGQPGLTYFEPAFVDELSEVMRWSFEHMQAPDGGSVYLRLTTRSLSQPERSDDAWRE
PALKGGYWLREPAEGSEAALVFCGAVAPEVLAAAEQLADDLPGLGVLNVVSPGLLHRDWMDARRGRWTRGERRRSHAEAL
LSRLAPGAGLVTVVDGSPATLSWLGGVRGMRVSALGLDSFGQVGDLPDLYRHYRLDVDAIVDAAAELFL
>Mature_788_residues
PRAQAVPAAGHNIGTADRTRALTRIDERLRWLATWTIHHANHLRESRDGLKVGGHQASCASMTTILTALYFHALRPEDRV
AVKPHASPVFHAAQYLMGRQTREQLEAFRSFGGAQSYPSRTKDKDDVDFSTGSVGLGVAITAFASLAQDYLKGHGLLDPA
REGRFVATLGDAELDEGNIYECLIEAYKHDIRNVWWIVDYNRQSLDATTADRMFDRFDDIFETAGWRVVTLKWGKAQERA
FARPGGAALRSWIEACSNAEYAALTYQGGAAWRARLTRDIGRESHVPALLESFSDEALHQLMIGLGGHCIETLTEAFDAA
ARDDTPTLFIAYTVKGFGLPLQGHKDNHAGLMTPSQVEALREAMGVPAGAEWEPYAGLPPEEAEALAAFVRDVPFAAEAD
RRPRAAPVPVPPREAFPAPDGAEQSTQAAFGRILLDLAKSGHPIADRIVTTSPDVTVSTNLGGFVNQRGLFRRRETADVF
RDAKIPSPQKWAGGRAGQHIELGIAEHNLFLNLGALGLTAPLFGERLLPIGTVYDPFISRGLDALNYACYQDARFMLVAT
PSGLTLGPEGGAHQSIYTPLIGIGQPGLTYFEPAFVDELSEVMRWSFEHMQAPDGGSVYLRLTTRSLSQPERSDDAWREP
ALKGGYWLREPAEGSEAALVFCGAVAPEVLAAAEQLADDLPGLGVLNVVSPGLLHRDWMDARRGRWTRGERRRSHAEALL
SRLAPGAGLVTVVDGSPATLSWLGGVRGMRVSALGLDSFGQVGDLPDLYRHYRLDVDAIVDAAAELFL

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=796, Percent_Identity=26.8844221105528, Blast_Score=179, Evalue=8e-46,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 85964; Mature: 85833

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRAQAVPAAGHNIGTADRTRALTRIDERLRWLATWTIHHANHLRESRDGLKVGGHQASC
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHH
ASMTTILTALYFHALRPEDRVAVKPHASPVFHAAQYLMGRQTREQLEAFRSFGGAQSYPS
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RTKDKDDVDFSTGSVGLGVAITAFASLAQDYLKGHGLLDPAREGRFVATLGDAELDEGNI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCCCCCHH
YECLIEAYKHDIRNVWWIVDYNRQSLDATTADRMFDRFDDIFETAGWRVVTLKWGKAQER
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
AFARPGGAALRSWIEACSNAEYAALTYQGGAAWRARLTRDIGRESHVPALLESFSDEALH
HHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QLMIGLGGHCIETLTEAFDAAARDDTPTLFIAYTVKGFGLPLQGHKDNHAGLMTPSQVEA
HHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
LREAMGVPAGAEWEPYAGLPPEEAEALAAFVRDVPFAAEADRRPRAAPVPVPPREAFPAP
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGAEQSTQAAFGRILLDLAKSGHPIADRIVTTSPDVTVSTNLGGFVNQRGLFRRRETADV
CCCCHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCEEEECCCCCHHHCCCHHHHHHHHHH
FRDAKIPSPQKWAGGRAGQHIELGIAEHNLFLNLGALGLTAPLFGERLLPIGTVYDPFIS
HHHCCCCCCCCCCCCCCCCEEEEEEEECEEEEEECHHHHHHHHHCCCCCCCCHHHHHHHH
RGLDALNYACYQDARFMLVATPSGLTLGPEGGAHQSIYTPLIGIGQPGLTYFEPAFVDEL
CCHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCHHHCCHHCCCCCCCCCCCHHHHHHH
SEVMRWSFEHMQAPDGGSVYLRLTTRSLSQPERSDDAWREPALKGGYWLREPAEGSEAAL
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCEECCCCCCCCEEE
VFCGAVAPEVLAAAEQLADDLPGLGVLNVVSPGLLHRDWMDARRGRWTRGERRRSHAEAL
EEECHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LSRLAPGAGLVTVVDGSPATLSWLGGVRGMRVSALGLDSFGQVGDLPDLYRHYRLDVDAI
HHHHCCCCCEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCHHHH
VDAAAELFL
HHHHHHHCC
>Mature Secondary Structure 
PRAQAVPAAGHNIGTADRTRALTRIDERLRWLATWTIHHANHLRESRDGLKVGGHQASC
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHH
ASMTTILTALYFHALRPEDRVAVKPHASPVFHAAQYLMGRQTREQLEAFRSFGGAQSYPS
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RTKDKDDVDFSTGSVGLGVAITAFASLAQDYLKGHGLLDPAREGRFVATLGDAELDEGNI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCCCCCHH
YECLIEAYKHDIRNVWWIVDYNRQSLDATTADRMFDRFDDIFETAGWRVVTLKWGKAQER
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
AFARPGGAALRSWIEACSNAEYAALTYQGGAAWRARLTRDIGRESHVPALLESFSDEALH
HHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QLMIGLGGHCIETLTEAFDAAARDDTPTLFIAYTVKGFGLPLQGHKDNHAGLMTPSQVEA
HHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
LREAMGVPAGAEWEPYAGLPPEEAEALAAFVRDVPFAAEADRRPRAAPVPVPPREAFPAP
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGAEQSTQAAFGRILLDLAKSGHPIADRIVTTSPDVTVSTNLGGFVNQRGLFRRRETADV
CCCCHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCEEEECCCCCHHHCCCHHHHHHHHHH
FRDAKIPSPQKWAGGRAGQHIELGIAEHNLFLNLGALGLTAPLFGERLLPIGTVYDPFIS
HHHCCCCCCCCCCCCCCCCEEEEEEEECEEEEEECHHHHHHHHHCCCCCCCCHHHHHHHH
RGLDALNYACYQDARFMLVATPSGLTLGPEGGAHQSIYTPLIGIGQPGLTYFEPAFVDEL
CCHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCHHHCCHHCCCCCCCCCCCHHHHHHH
SEVMRWSFEHMQAPDGGSVYLRLTTRSLSQPERSDDAWREPALKGGYWLREPAEGSEAAL
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCCCEECCCCCCCCEEE
VFCGAVAPEVLAAAEQLADDLPGLGVLNVVSPGLLHRDWMDARRGRWTRGERRRSHAEAL
EEECHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
LSRLAPGAGLVTVVDGSPATLSWLGGVRGMRVSALGLDSFGQVGDLPDLYRHYRLDVDAI
HHHHCCCCCEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCHHHH
VDAAAELFL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA