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The map label for this gene is lpsC [H]

Identifier: 197103476

GI number: 197103476

Start: 6662

End: 8209

Strand: Direct

Name: lpsC [H]

Synonym: PHZ_c0010

Alternate gene names: 197103476

Gene position: 6662-8209 (Clockwise)

Preceding gene: 197103475

Following gene: 197103477

Centisome position: 0.17

GC content: 71.64

Gene sequence:

>1548_bases
TTGGCTCGACTCGCGGTCTCGACTAGCGTCCCGCCGACGCATGTCCGGAAAACTCGCCAACTTCATCGACCTGCCGGTGA
TCTCGGATCCCCGGGGGAATCTGTGCTTTGCGGAATCGAACCGGCATGTCCCGTTCGCGATCGAGCGGGTCTACTACCTC
TACGACGTGCCCAGCGGCTCTATGCGGGCCGGTCACGCCCACCTGGCGCTGAACCAGCTGCTGCTGGCGGTCTCGGGCAG
CTTCGACGTGCGCCTGCACGACGGGACCACCGAGGAGGTGGTGACCCTGAACCGCCCGCACCGGGGCCTGCACATCGGGC
CGAACCTGTGGCGAGAGATCGAGAATTTCTCGTCGGGGGCGGTCTGCATGGTGCTGGCCTCGATGGTCTACGACGAGAGC
GATTACATCCGCGACTTCGACGCCTTCCTGGCTCACGCCCGCCGATGAAGTTCTTCGACCTGGGCCTGGCCGAGGACGGC
CTGCGAAGCGAGCTGGACGCCGCCTACGCCCGGGTGATCGATTCCGGCTGGACCATCCTGGGCGCCGAGATGGAGGCGTT
CGAGCGTGAGTTCGCCGCCTTCTGCGGGGCGAAGCACGCGGTCGGCGTCGGCAACGGCCTCGACGCCCTGGTGCTGGCGC
TGCGGGCCGCCGGCGTCGGCCCGGGCGCCGAGGTGATCGTCCCCTCGCACACCTTCATCGCCACCTGGCTGGCGGTGGCG
GCGGTCGGGGCCACCATCATCCCCGTCGAGGCCGATCCTCGGACCTACACCCTGGACCCACAGGCCGCGGCTGCGGCGGT
GACGCCGAAGACGGCGGCGATCCTGCCGGTCTCGCTCTACGGCCACCCGGCCGACATGGACGCCCTGATGGAGCTGGCCG
CCCGGCACGGCCTCTTCGTGCTGGAGGACGCCGCCCAGAGCCACGGCGCCGAGCACCGGGGGCGGCGGACGGGCGCGCTG
GCGCACGCCACCGCGTTCAGCTTCTATCCGACCAAGAACCTGGGCGCCCTCGGCGACGCCGGCGCGGTGACGACCGACGA
TCCCGCGCTAGCCGACCGCCTGCGGCGCCTGCGCAACTACGGCTCGGAGCGCAAGTACGTCCACGAGGTGGTGGGCGTGA
ACTCGCGGCTGGATGAGCTGCAGGCGGCGTTCCTGCGGGTCTTCCTGCCGAGGCTCGAAGCCCGGAATGCGCGACGCCGC
GAGGTCGCCGCCGCCTACGCGCGGTCGCTGCCGACCGACATCGTCACGCCGCCGGGCGAGGCCGACTGGGCCCGGGCGGT
CTACCACCTCTACGTCGTGCGCAGCGCCCGGCGCGACGCCCTGCAGGCGAAGCTGGCCGAGGCCGGCGTGCAGACCCTGA
TCCACTATCCCACGCCGTGCCACCTGCAGCCGGCGTTCGCCCACCTGGGCTTCCGGGCCGGGCAGTTCCCGCTCGCCGAG
CGGCTGGCGGCCGAGGTGCTCTCGCTGCCCATGTGGCCGGGCATGACCCCGGCCGACGCGGAAGCGGTCGCAGCGGCGAT
CCGGAGGACGGAGGAGGGCGGCTCGTGA

Upstream 100 bases:

>100_bases
GCATGGCGGGGCCGGCGCGCTCTATGTCGCCCTGAAGCGCAAGCCTCCGAGGTGAGCCAGGGGGTGAGCCAGGGGGTGAG
CCAGGGGATGCAGGCCGCGC

Downstream 100 bases:

>100_bases
GCGCGGCCGGCCTCCTGGAGCCCCTCGAGCAGCAGGCGGCGCTGTTCGCCGCCGCGCCCAACCGATTCAGCCTCATGAAG
GCCGCGCGGGGAGCGCCCGC

Product: perosamine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MARLAVSTSVPPTHVRKTRQLHRPAGDLGSPGESVLCGIEPACPVRDRAGLLPLRRAQRLYAGRSRPPGAEPAAAGGLGQ
LRRAPARRDHRGGGDPEPPAPGPAHRAEPVARDREFLVGGGLHGAGLDGLRRERLHPRLRRLPGSRPPMKFFDLGLAEDG
LRSELDAAYARVIDSGWTILGAEMEAFEREFAAFCGAKHAVGVGNGLDALVLALRAAGVGPGAEVIVPSHTFIATWLAVA
AVGATIIPVEADPRTYTLDPQAAAAAVTPKTAAILPVSLYGHPADMDALMELAARHGLFVLEDAAQSHGAEHRGRRTGAL
AHATAFSFYPTKNLGALGDAGAVTTDDPALADRLRRLRNYGSERKYVHEVVGVNSRLDELQAAFLRVFLPRLEARNARRR
EVAAAYARSLPTDIVTPPGEADWARAVYHLYVVRSARRDALQAKLAEAGVQTLIHYPTPCHLQPAFAHLGFRAGQFPLAE
RLAAEVLSLPMWPGMTPADAEAVAAAIRRTEEGGS

Sequences:

>Translated_515_residues
MARLAVSTSVPPTHVRKTRQLHRPAGDLGSPGESVLCGIEPACPVRDRAGLLPLRRAQRLYAGRSRPPGAEPAAAGGLGQ
LRRAPARRDHRGGGDPEPPAPGPAHRAEPVARDREFLVGGGLHGAGLDGLRRERLHPRLRRLPGSRPPMKFFDLGLAEDG
LRSELDAAYARVIDSGWTILGAEMEAFEREFAAFCGAKHAVGVGNGLDALVLALRAAGVGPGAEVIVPSHTFIATWLAVA
AVGATIIPVEADPRTYTLDPQAAAAAVTPKTAAILPVSLYGHPADMDALMELAARHGLFVLEDAAQSHGAEHRGRRTGAL
AHATAFSFYPTKNLGALGDAGAVTTDDPALADRLRRLRNYGSERKYVHEVVGVNSRLDELQAAFLRVFLPRLEARNARRR
EVAAAYARSLPTDIVTPPGEADWARAVYHLYVVRSARRDALQAKLAEAGVQTLIHYPTPCHLQPAFAHLGFRAGQFPLAE
RLAAEVLSLPMWPGMTPADAEAVAAAIRRTEEGGS
>Mature_514_residues
ARLAVSTSVPPTHVRKTRQLHRPAGDLGSPGESVLCGIEPACPVRDRAGLLPLRRAQRLYAGRSRPPGAEPAAAGGLGQL
RRAPARRDHRGGGDPEPPAPGPAHRAEPVARDREFLVGGGLHGAGLDGLRRERLHPRLRRLPGSRPPMKFFDLGLAEDGL
RSELDAAYARVIDSGWTILGAEMEAFEREFAAFCGAKHAVGVGNGLDALVLALRAAGVGPGAEVIVPSHTFIATWLAVAA
VGATIIPVEADPRTYTLDPQAAAAAVTPKTAAILPVSLYGHPADMDALMELAARHGLFVLEDAAQSHGAEHRGRRTGALA
HATAFSFYPTKNLGALGDAGAVTTDDPALADRLRRLRNYGSERKYVHEVVGVNSRLDELQAAFLRVFLPRLEARNARRRE
VAAAYARSLPTDIVTPPGEADWARAVYHLYVVRSARRDALQAKLAEAGVQTLIHYPTPCHLQPAFAHLGFRAGQFPLAER
LAAEVLSLPMWPGMTPADAEAVAAAIRRTEEGGS

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=387, Percent_Identity=33.3333333333333, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI2367285, Length=315, Percent_Identity=32.0634920634921, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 54884; Mature: 54753

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLAVSTSVPPTHVRKTRQLHRPAGDLGSPGESVLCGIEPACPVRDRAGLLPLRRAQRL
CCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHH
YAGRSRPPGAEPAAAGGLGQLRRAPARRDHRGGGDPEPPAPGPAHRAEPVARDREFLVGG
HCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEEC
GLHGAGLDGLRRERLHPRLRRLPGSRPPMKFFDLGLAEDGLRSELDAAYARVIDSGWTIL
CCCCCCCHHHHHHHHCHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEE
GAEMEAFEREFAAFCGAKHAVGVGNGLDALVLALRAAGVGPGAEVIVPSHTFIATWLAVA
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHH
AVGATIIPVEADPRTYTLDPQAAAAAVTPKTAAILPVSLYGHPADMDALMELAARHGLFV
HHCCEEEEECCCCCEEEECCCHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEE
LEDAAQSHGAEHRGRRTGALAHATAFSFYPTKNLGALGDAGAVTTDDPALADRLRRLRNY
EEHHHHHCCHHHCCCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GSERKYVHEVVGVNSRLDELQAAFLRVFLPRLEARNARRREVAAAYARSLPTDIVTPPGE
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
ADWARAVYHLYVVRSARRDALQAKLAEAGVQTLIHYPTPCHLQPAFAHLGFRAGQFPLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHH
RLAAEVLSLPMWPGMTPADAEAVAAAIRRTEEGGS
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARLAVSTSVPPTHVRKTRQLHRPAGDLGSPGESVLCGIEPACPVRDRAGLLPLRRAQRL
CCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHH
YAGRSRPPGAEPAAAGGLGQLRRAPARRDHRGGGDPEPPAPGPAHRAEPVARDREFLVGG
HCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEEC
GLHGAGLDGLRRERLHPRLRRLPGSRPPMKFFDLGLAEDGLRSELDAAYARVIDSGWTIL
CCCCCCCHHHHHHHHCHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEE
GAEMEAFEREFAAFCGAKHAVGVGNGLDALVLALRAAGVGPGAEVIVPSHTFIATWLAVA
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHH
AVGATIIPVEADPRTYTLDPQAAAAAVTPKTAAILPVSLYGHPADMDALMELAARHGLFV
HHCCEEEEECCCCCEEEECCCHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEE
LEDAAQSHGAEHRGRRTGALAHATAFSFYPTKNLGALGDAGAVTTDDPALADRLRRLRNY
EEHHHHHCCHHHCCCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GSERKYVHEVVGVNSRLDELQAAFLRVFLPRLEARNARRREVAAAYARSLPTDIVTPPGE
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
ADWARAVYHLYVVRSARRDALQAKLAEAGVQTLIHYPTPCHLQPAFAHLGFRAGQFPLAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHH
RLAAEVLSLPMWPGMTPADAEAVAAAIRRTEEGGS
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]