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The map label for this gene is sdaAA [H]

Identifier: 195979022

GI number: 195979022

Start: 1996022

End: 1996894

Strand: Direct

Name: sdaAA [H]

Synonym: Sez_1934

Alternate gene names: 195979022

Gene position: 1996022-1996894 (Clockwise)

Preceding gene: 195979021

Following gene: 195979023

Centisome position: 98.61

GC content: 45.25

Gene sequence:

>873_bases
ATGTTTTACACAATTGAAGAGCTTGTCAAGCAAGCTGATGATAGATTTGATGGTAATGTAGCAGAGCTAATGATTGCTAC
AGAGGTTGAAATGACTGGTCGAAGCAGGGAAGAAATTCTATCCATCATGTCACAGCATTTACAGGTAATGAAGGATTCTG
TTGTCAGCGGATTGACAGCAACCAAATCTATTAGCGGCTTAACTGGCGGTGATGCTCTTAAGATGGATCATTACATCAAA
AAAGGAAAGGGGCTTTCAGATCAAACCATTTTAACAGCTGTGAGAAATGCTATGGCTGTCAATGAGCTAAATGCAAAAAT
GGGACTTGTTTGTGCAACACCGACTGCTGGAAGTGCGGGCTGTCTACCTGCAGTCCTTGCTGTTGCTATTGATAAGCTCA
AGCTATCAGAAAAGGAGCAGCTGGACTTTCTCTTTACAGCCGGTGCCTTTGGCTTAGTCATTGGAAATAATGCCTCTATC
TCTGGAGCAGAAGGAGGCTGTCAAGCCGAGGTGGGCTCTGCCTCTGCAATGAGTGCTGCAGCCCTTGTTAAGGCAGCAGG
TGGTACTGCTTATCAGGCTAGCCAAGCGGTAGCCTTTGTAATCAAAAATCTATTGGGATTGGTTTGTGATCCTGTTGCTG
GATTGGTCGAAGTTCCCTGTGTTAAGCGTAATGCATTAGGATCAAGCTTTGCTCTTGTTGCTGCTGATATGGCATTGGCT
GATATTCAGTCACAAATTCCTGTAGATGAGGTCGTTGACGCCATGTATCAGGTTGGTGCCGCAATGCCAACAGCCTTTAA
GGAGACAGCTGAGGGAGGATTAGCAGCAACCCCAACAGGTAGACGGTATAGTAAAGAGATTTTCGGAGACTAA

Upstream 100 bases:

>100_bases
TTATTGAGGTTGATTCTCGTGACTGTCAAGCTGCTGTTAAGCAGATTGCAACTATCCCTAATCTGCATAATGTCAATTTC
TTTGACTAGAAAGGTATGTC

Downstream 100 bases:

>100_bases
TATAATCACGTAAAGATAGACTGAGGAGACAGTATGAAAGCAATCCTATTTGACTTAGATGGTACTTTGGTGGACTCTAG
TATAGGAATACTAAACGCCT

Product: probable L-serine dehydratase alpha chain SdaAA

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSREEILSIMSQHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIK
KGKGLSDQTILTAVRNAMAVNELNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEVPCVKRNALGSSFALVAADMALA
DIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAATPTGRRYSKEIFGD

Sequences:

>Translated_290_residues
MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSREEILSIMSQHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIK
KGKGLSDQTILTAVRNAMAVNELNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEVPCVKRNALGSSFALVAADMALA
DIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAATPTGRRYSKEIFGD
>Mature_290_residues
MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSREEILSIMSQHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIK
KGKGLSDQTILTAVRNAMAVNELNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEVPCVKRNALGSSFALVAADMALA
DIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAATPTGRRYSKEIFGD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=283, Percent_Identity=34.982332155477, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1788116, Length=181, Percent_Identity=44.7513812154696, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1789161, Length=261, Percent_Identity=36.0153256704981, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29963; Mature: 29963

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSREEILSIMSQHLQVMKDSVVSGLTA
CCCCHHHHHHHHHCCCCCCHHHEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNELNAKMGLVCATPTAGSAG
HHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
CLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASISGAEGGCQAEVGSASAMSAA
HHHHHHHHHHHHHHCCCHHHHHEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
ALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEVPCVKRNALGSSFALVAADMALA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH
DIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAATPTGRRYSKEIFGD
HHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCCHHHHHHCCC
>Mature Secondary Structure
MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSREEILSIMSQHLQVMKDSVVSGLTA
CCCCHHHHHHHHHCCCCCCHHHEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNELNAKMGLVCATPTAGSAG
HHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
CLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASISGAEGGCQAEVGSASAMSAA
HHHHHHHHHHHHHHCCCHHHHHEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
ALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEVPCVKRNALGSSFALVAADMALA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHH
DIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAATPTGRRYSKEIFGD
HHHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]