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The map label for this gene is galE [H]

Identifier: 195978839

GI number: 195978839

Start: 1800201

End: 1801211

Strand: Direct

Name: galE [H]

Synonym: Sez_1743

Alternate gene names: 195978839

Gene position: 1800201-1801211 (Clockwise)

Preceding gene: 195978838

Following gene: 195978840

Centisome position: 88.94

GC content: 46.88

Gene sequence:

>1011_bases
ATGACTGTTCTAGTTTTAGGCGGTGCAGGCTACATTGGATCACATACCGTAGACCGTCTCGTAGCACAGGGAAAAGAAAA
AGTCGTTGTTGTTGATAGCTTGGTGACAGGACACCGCAAGGCTGTTCACCCAGAGGCTATGTTTTACAAAGGAGACTTAG
CAGACAAAGCCTTTATGCGTCAAGTCTTTAGGGACAATCCAGACATAGACACTGTCATTCACTTTGCTGCCTCTTCCTTG
GTCGCAGAATCGATGACAGACCCTCTGAAATACTTTGACAATAACACAGCAGGTATGATTAAGCTGCTTGAGGTCATGAG
AGAAGCCAAGGTTAAGCGCATTGTCTTTTCATCAACAGCAGCCGTCTATGGCATTCCAAAAACAGTTCCCATCTTAGAGT
CAGCGCCTAAATGCCCAATCAATCCTTATGGCCAAAGCAAGCTTATGATGGAAACGATAATGACCTGGGCCGACAAAGCC
TATGGCATCACATTTGTGGCCCTTCGCTACTTCAATGTTGCCGGAGCAAAGCCAGATGGCTCCATCGGTGAAGACCACGA
GCCAGAAACACATTTATTACCCATTATCCTACAGACTGCACAGGGAGTGCGTGAGCAGGTGATGATTTTTGGTGATGATT
ATGACACACCAGATGGTACTAACGTTCGAGATTACGTCCATCCTATCGATTTAGCTGATGCACACATTTTAGCAATGGCA
TATCTGCGTCAGGGCAAACCATCACAGGTCTTTAATCTAGGCTCCCAAACAGGCTTTTCCAATCGTCAACTGCTTGAAGC
CGCTCGTCGGGTAACAGGACAAGCCATACCAGCCAAAAAAGCTGCAAGACGTCCCGGTGACCCAGACACCTTAATTGCGT
CATCAGAAAAAGCACGCAAGGTTCTCAATTGGAAGCCAAGCTATGACGATATTGACAAGATAATCGCATCAGCCTGGGCC
TGGCATACCAAGCACCCAAAAGGGTATGACGATAAAACAAGTGGCAGCTAG

Upstream 100 bases:

>100_bases
GGACGCTGGCGTCTACAAACGTGATCAAGAAGGTCAAGCAGCCTTTATGCGTTTTCTTAAGAGCATTGGCATTGAAGCAA
TTGAAGAATAGGAGGAAAAA

Downstream 100 bases:

>100_bases
TCCCTCAAGGCAGCTACCACAGCAAGTACTCAGCCTCTCTTAATTCATACACCTATACTAATAGGAGAAATAAACTGTGA
ACATTTATCAAGACATCATT

Product: UDP-glucose 4-epimerase GalE

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTVLVLGGAGYIGSHTVDRLVAQGKEKVVVVDSLVTGHRKAVHPEAMFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSL
VAESMTDPLKYFDNNTAGMIKLLEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPDGTNVRDYVHPIDLADAHILAMA
YLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAIPAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWA
WHTKHPKGYDDKTSGS

Sequences:

>Translated_336_residues
MTVLVLGGAGYIGSHTVDRLVAQGKEKVVVVDSLVTGHRKAVHPEAMFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSL
VAESMTDPLKYFDNNTAGMIKLLEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPDGTNVRDYVHPIDLADAHILAMA
YLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAIPAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWA
WHTKHPKGYDDKTSGS
>Mature_335_residues
TVLVLGGAGYIGSHTVDRLVAQGKEKVVVVDSLVTGHRKAVHPEAMFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLV
AESMTDPLKYFDNNTAGMIKLLEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKAY
GITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPDGTNVRDYVHPIDLADAHILAMAY
LRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAIPAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAW
HTKHPKGYDDKTSGS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=39.3063583815029, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=39.3063583815029, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=39.3063583815029, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI7657641, Length=269, Percent_Identity=28.2527881040892, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI42516563, Length=317, Percent_Identity=24.6056782334385, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1786974, Length=343, Percent_Identity=41.6909620991254, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1788353, Length=369, Percent_Identity=25.4742547425474, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994969, Length=333, Percent_Identity=26.7267267267267, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790049, Length=256, Percent_Identity=28.125, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788366, Length=348, Percent_Identity=23.8505747126437, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=36.7816091954023, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=36.5714285714286, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17539532, Length=250, Percent_Identity=27.6, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=352, Percent_Identity=26.9886363636364, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568069, Length=277, Percent_Identity=27.4368231046931, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=346, Percent_Identity=39.5953757225434, Blast_Score=235, Evalue=7e-63,
Organism=Drosophila melanogaster, GI19923002, Length=352, Percent_Identity=39.4886363636364, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI21356223, Length=317, Percent_Identity=26.813880126183, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36975; Mature: 36844

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVLGGAGYIGSHTVDRLVAQGKEKVVVVDSLVTGHRKAVHPEAMFYKGDLADKAFMR
CEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECHHHCCHHHCCCHHHEEECCHHHHHHHH
QVFRDNPDIDTVIHFAASSLVAESMTDPLKYFDNNTAGMIKLLEVMREAKVKRIVFSSTA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCH
AVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKAYGITFVALRYFNVAGAKPDG
HHCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
SIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPDGTNVRDYVHPIDLADAHILAMA
CCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHH
YLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAIPAKKAARRPGDPDTLIASSEKARK
HHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEECCHHHHH
VLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKTSGS
HHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVLVLGGAGYIGSHTVDRLVAQGKEKVVVVDSLVTGHRKAVHPEAMFYKGDLADKAFMR
EEEEEECCCCCCHHHHHHHHHCCCCCEEEEECHHHCCHHHCCCHHHEEECCHHHHHHHH
QVFRDNPDIDTVIHFAASSLVAESMTDPLKYFDNNTAGMIKLLEVMREAKVKRIVFSSTA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCH
AVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKAYGITFVALRYFNVAGAKPDG
HHCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
SIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPDGTNVRDYVHPIDLADAHILAMA
CCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHH
YLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAIPAKKAARRPGDPDTLIASSEKARK
HHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEECCHHHHH
VLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKTSGS
HHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973358; 12397186 [H]