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The map label for this gene is aroA [H]

Identifier: 195978591

GI number: 195978591

Start: 1525320

End: 1526075

Strand: Direct

Name: aroA [H]

Synonym: Sez_1489

Alternate gene names: 195978591

Gene position: 1525320-1526075 (Clockwise)

Preceding gene: 195978590

Following gene: 195978592

Centisome position: 75.36

GC content: 41.93

Gene sequence:

>756_bases
ATGGGAAACGATATAATAGCTGATTTTTTAAACAAGGGCTGTCAAAAGAGTAACTTTATTGTTGGTCCCTGTGCCATTGA
ATCTTATCAGCAAATCAGACAGGCAGCAGCAAGTGCCAAGGCTTTAGGCTACAAGTATTTTCGAGGGGGAGCCTATAAGC
CCAGAACCTCTTCTAACTCCTTTCAAGGCTTAGGGCTGACAGGGGTTACCTATCTACATGAGGTTTGCCAGGAATTTTCG
CTGAAGGCTGTTAGTGAGATTATGTCTGAAAGACAGCTAGAGGAAGCCTATGACTATTTAGATATTATTCAGATTGGCGC
TCGAAATATGCAAAATTTTGAACTGTTAAAGGTATTGTCAAAGATTGACAAGCCTATCTTGTTTAAACGAGGACTAATGG
CAACCATTGAGGAATATTTGGGTGCTTTATCTTATTTACAAGAAAATGGCAAGCAAAATATTATTTTATGCGAGCGTGGG
GTTCGTGGCTATGATGTGGAAACTAGAAATATGCTAGACATCATGGCAGTCCCTATTATTCAGCAAAAGGTGAAGCTGCC
AATCATTGTTGATGTCTCTCACTCAACAGGAAGAAGAGATTTACTATTGCCTGCGGCTAAGGCCGCTAAGGCTATCGGTG
CCAATGGTATTATGATGGAGGTGCACCCTACACCTGATCTTGCTTTGTCAGATGCCGCACAGCAGATTGACTATCAACAG
CTAGAGCAGCTTGGAAAAGAGCTTTGGGAAAGCTAA

Upstream 100 bases:

>100_bases
ATAGTTCTGTCATGCCTTATTCACAGTATTATCTAAGACAGAGCTGTCATCTTACCTTTGGGGAATCATTCTCTCAATAT
CATATTAGGAAAGAGTATAA

Downstream 100 bases:

>100_bases
CTAACAGCAGTCACCGATCCAGTCATTCGGACTGATGGTGCTTAGGAGAGAAAGACGCATGACACAAACACTTCAGGTTA
AGTCTCGTATCACTGACTAT

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGYKYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFS
LKAVSEIMSERQLEEAYDYLDIIQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIMMEVHPTPDLALSDAAQQIDYQQ
LEQLGKELWES

Sequences:

>Translated_251_residues
MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGYKYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFS
LKAVSEIMSERQLEEAYDYLDIIQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIMMEVHPTPDLALSDAAQQIDYQQ
LEQLGKELWES
>Mature_250_residues
GNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGYKYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSL
KAVSEIMSERQLEEAYDYLDIIQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERGV
RGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIMMEVHPTPDLALSDAAQQIDYQQL
EQLGKELWES

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=215, Percent_Identity=28.8372093023256, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 27940; Mature: 27808

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGYKYFRGGAYKPRTSSNS
CCCHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDIIQIGARNMQNFELLKVLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERGVRGYDVETRNMLDIMAVPII
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
QQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIMMEVHPTPDLALSDAAQQIDYQQ
HHHCCCCEEEEECCCCCCCCEECHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHH
LEQLGKELWES
HHHHHHHHHCC
>Mature Secondary Structure 
GNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGYKYFRGGAYKPRTSSNS
CCHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDIIQIGARNMQNFELLKVLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERGVRGYDVETRNMLDIMAVPII
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
QQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIMMEVHPTPDLALSDAAQQIDYQQ
HHHCCCCEEEEECCCCCCCCEECHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHH
LEQLGKELWES
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]