Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 195978592

GI number: 195978592

Start: 1526110

End: 1527216

Strand: Direct

Name: aroB [H]

Synonym: Sez_1490

Alternate gene names: 195978592

Gene position: 1526110-1527216 (Clockwise)

Preceding gene: 195978591

Following gene: 195978593

Centisome position: 75.39

GC content: 43.81

Gene sequence:

>1107_bases
ATGGTGCTTAGGAGAGAAAGACGCATGACACAAACACTTCAGGTTAAGTCTCGTATCACTGACTATCCGATTATCTTTGC
AGACGATGTTTTTCAGCCGCTGAATCAATTTCTTGCTGAAAAAGGAGATGTCAAGCTATTGTTTATCACTGACCAAACGG
TATTTGATTTATACCAGCCTTTATTTAGACGTTTTCAACAGGATTACGATAGTTATCTTCATATTGCTGCTCCAGGGGGG
CAATCTAAATCTCTAGAGGAGGCTAGCCGAATTTACGATCAACTGATTAGAGCTAATTTTTCTAAGAAGGACATCATTGT
TACTGTTGGAGGAGGGGTGATTGGAGATCTTGGGGGATTTGTTGCGGCAACCTTTTACCGCGGGATTTCCTACGTTCAGA
TTCCAACAACCTTACTTAGTCAGGTAGATAGCAGTATTGGTGGTAAGGTTGGGGTTCATTTTAAGGGCTTGACCAATATG
ATAGGCAGTATCTACCCTCCAAACCAGATTATCGTGTCTACCAAGTTTTTGGACACGCTTCCTGAAAGAGAATTTGCCTG
CGGCATCAGCGAAATGATTAAAATCGGTTTTATTCATGATCGCAAGCTCTTTCAACAGCTCCTAGCCTTCCCCAAGGACC
GCAATCAAGAGCAGCTCAGGCAAATGATTTTTCAAGCGATTTGCCATAAAAAAAGAGTGGTTGAAAAAGATGAATTTGAA
GGTAATCTCCGCATGTCCTTAAATTTCGGGCATACGCTAGGGCATGCGGTTGAAGCCTTGTGCCATCACGAGCTTTACAG
GCATGGCGAGGCTATTGCGATTGGCATGGTCTTTGAGGCCAAGCTGGCCGTCCAGCAGCAACTACTGAGCCAACAGGATT
TAGAGGCATTACAGGCTGCCTTTGAGGCTTATCAGCTACCGACCACACTTGAGGCTAAGTCAATGACAGCCGAAGCCTTG
ATGACTGTTTTAAAAACAGATAAGAAAAATTCTGGTCAGCATATTGTCCTTATTTTGCCAACGACGGAAGGCTATATAAG
CTTTCCTATCGCTAAGCATGACAATCACCTGCTGGATTGGCTAAGAAGCCTGCTAGATATCGCCTGA

Upstream 100 bases:

>100_bases
GATGCCGCACAGCAGATTGACTATCAACAGCTAGAGCAGCTTGGAAAAGAGCTTTGGGAAAGCTAACTAACAGCAGTCAC
CGATCCAGTCATTCGGACTG

Downstream 100 bases:

>100_bases
GAAGGCTTTTCTCCTGTCTTATTAGTCGAGTGAAAAAACTTGCTGCTTCTGAAAAACAAAAAGGCTTCAAAGCCTCTTGT
GATATACTCCCCTTATAGTG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MVLRRERRMTQTLQVKSRITDYPIIFADDVFQPLNQFLAEKGDVKLLFITDQTVFDLYQPLFRRFQQDYDSYLHIAAPGG
QSKSLEEASRIYDQLIRANFSKKDIIVTVGGGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNM
IGSIYPPNQIIVSTKFLDTLPEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQAICHKKRVVEKDEFE
GNLRMSLNFGHTLGHAVEALCHHELYRHGEAIAIGMVFEAKLAVQQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEAL
MTVLKTDKKNSGQHIVLILPTTEGYISFPIAKHDNHLLDWLRSLLDIA

Sequences:

>Translated_368_residues
MVLRRERRMTQTLQVKSRITDYPIIFADDVFQPLNQFLAEKGDVKLLFITDQTVFDLYQPLFRRFQQDYDSYLHIAAPGG
QSKSLEEASRIYDQLIRANFSKKDIIVTVGGGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNM
IGSIYPPNQIIVSTKFLDTLPEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQAICHKKRVVEKDEFE
GNLRMSLNFGHTLGHAVEALCHHELYRHGEAIAIGMVFEAKLAVQQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEAL
MTVLKTDKKNSGQHIVLILPTTEGYISFPIAKHDNHLLDWLRSLLDIA
>Mature_368_residues
MVLRRERRMTQTLQVKSRITDYPIIFADDVFQPLNQFLAEKGDVKLLFITDQTVFDLYQPLFRRFQQDYDSYLHIAAPGG
QSKSLEEASRIYDQLIRANFSKKDIIVTVGGGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNM
IGSIYPPNQIIVSTKFLDTLPEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQAICHKKRVVEKDEFE
GNLRMSLNFGHTLGHAVEALCHHELYRHGEAIAIGMVFEAKLAVQQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEAL
MTVLKTDKKNSGQHIVLILPTTEGYISFPIAKHDNHLLDWLRSLLDIA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=349, Percent_Identity=34.9570200573066, Blast_Score=173, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320332, Length=299, Percent_Identity=34.4481605351171, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 41651; Mature: 41651

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLRRERRMTQTLQVKSRITDYPIIFADDVFQPLNQFLAEKGDVKLLFITDQTVFDLYQP
CCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHH
LFRRFQQDYDSYLHIAAPGGQSKSLEEASRIYDQLIRANFSKKDIIVTVGGGVIGDLGGF
HHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
VAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPNQIIVSTKFLDTL
HHHHHHHCCCEEEHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCEEEEEEHHHHHC
PEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQAICHKKRVVEKDEFE
CCHHHHCCHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GNLRMSLNFGHTLGHAVEALCHHELYRHGEAIAIGMVFEAKLAVQQQLLSQQDLEALQAA
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
FEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTTEGYISFPIAKHDNHLLDW
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECCCCCCCCHHHHH
LRSLLDIA
HHHHHCCC
>Mature Secondary Structure
MVLRRERRMTQTLQVKSRITDYPIIFADDVFQPLNQFLAEKGDVKLLFITDQTVFDLYQP
CCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHH
LFRRFQQDYDSYLHIAAPGGQSKSLEEASRIYDQLIRANFSKKDIIVTVGGGVIGDLGGF
HHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
VAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPNQIIVSTKFLDTL
HHHHHHHCCCEEEHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCEEEEEEHHHHHC
PEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQAICHKKRVVEKDEFE
CCHHHHCCHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GNLRMSLNFGHTLGHAVEALCHHELYRHGEAIAIGMVFEAKLAVQQQLLSQQDLEALQAA
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
FEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTTEGYISFPIAKHDNHLLDW
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEECCCCCCCCHHHHH
LRSLLDIA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA