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The map label for this gene is murN [H]

Identifier: 195978425

GI number: 195978425

Start: 1355405

End: 1356640

Strand: Direct

Name: murN [H]

Synonym: Sez_1320

Alternate gene names: 195978425

Gene position: 1355405-1356640 (Clockwise)

Preceding gene: 195978424

Following gene: 195978428

Centisome position: 66.96

GC content: 42.72

Gene sequence:

>1236_bases
ATGGCTTTAGATATCATTGACAAAGAAACCTTTGGCTCATTTTGCAGTCAAGTGGAGTATAAATCCTTCATTCAATCCAT
AGAAATGGCAGAGCTGCTGCAAAAGCGTGGCTATCAAACACAATACCTTGCAATCAGTGACCAGAAAGATATTAAGGTTG
CAGCCATTCTCTACAGTGTAGCAATGGCCGGCGGCTTACGCATGGAAATCAACTCAGGTCCCGTAGTGGCTGATACGACC
TACACAACAGCCTTTTACAAAGCCCTACAGGACTATGCCAAACAGCAGGGAGCTCTTGAGCTAGTCATCAAGCCCTACGA
TACCTATCAGACCTTTACCGGTGATGGTCACCCAAATGATGATGAAAAGCCAGAACTGATCAAGGCCTTGACAAAGCTCA
ATTTTACACATGATGGCCTGTTAACAGGCTATCCTAACGGTGAGGGCGATTGGCATTATGTTAAAGAGTTAAGTGGCTTA
ACCTCTGCTAACTTAATCAAATCCTTCAGTAAAAAAGGCAAAGCCCTGCTAAAAAAAGCCAAAACCTTTGGCATTAAGCT
ACATAAGCTCAGTCGTGATGAGCTAACGCAATTCAAGGCAATTACTGCTGCTACATCTAGTCGAAGAGATTATACCGACA
AGTCTTTATCTTATTATCAGGATTTCTATGATAGCTTTGGGGATAGCTGTGAATTTATGGTTGCAACCCTCAATTTTGAT
GACTACCTCGCCAACCTAAGGCACAGCCAAGACAGGCTAAAGCAAGGCATGGCTAAATTAGAGGCAGACCTAGCTAAAAA
CCCAAGATCAGAAAAGAAGCAAAATCGGCTTCGGGAGCTCTCCAGCCAATTTGATACCTTTCAAGTTCGGGTAGCTGAAG
CACAGGAGTTGATTATCAAGTATGGCAAAAAAGACGTTCCTCTAGCTGGTAGTCTCTTTGTTTACACCCCGCAGGAGGCT
GTCTATCTCTTTTCTGGCTCCTATCCAGAATTTAACAGGTTCTACGCGCCAGCTCTATTACAAGAACATGTCATGCTAAG
AGCGATTGAAAAGGGAATCAGCTGCTATAATTTTCTTGGTATCATGGGTGAATTTGATGGCTCCGATGGTGTTTTACGCT
TTAAGCAAAACTTTAACGGCTATATCACACGAAAGATGGGAACCTTTAGGTATTATCCAAAGCCCTTCAAATATAAAGCT
ATCAAAACCATCAAAGCCTTGATTAGTCGCAGCTAA

Upstream 100 bases:

>100_bases
TCGAAGAATTTGCAGGAGAATTCAGCATTCCAGTTGGACCTATCTCAAAAGTGGCCATGATAGCCTATAATCTGAGAAAA
AAACTAAGGAGTAACCCTTA

Downstream 100 bases:

>100_bases
GTCAAGCTAGTAGCTAAACAGCCTTTTAAGCCTTCCAATGACTATTGGACACAATTGATAAAGCCTTGATTGCCTTACTC
AGAAACTCTTTAGTAAAGCC

Product: MurN protein

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance A [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MALDIIDKETFGSFCSQVEYKSFIQSIEMAELLQKRGYQTQYLAISDQKDIKVAAILYSVAMAGGLRMEINSGPVVADTT
YTTAFYKALQDYAKQQGALELVIKPYDTYQTFTGDGHPNDDEKPELIKALTKLNFTHDGLLTGYPNGEGDWHYVKELSGL
TSANLIKSFSKKGKALLKKAKTFGIKLHKLSRDELTQFKAITAATSSRRDYTDKSLSYYQDFYDSFGDSCEFMVATLNFD
DYLANLRHSQDRLKQGMAKLEADLAKNPRSEKKQNRLRELSSQFDTFQVRVAEAQELIIKYGKKDVPLAGSLFVYTPQEA
VYLFSGSYPEFNRFYAPALLQEHVMLRAIEKGISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYYPKPFKYKA
IKTIKALISRS

Sequences:

>Translated_411_residues
MALDIIDKETFGSFCSQVEYKSFIQSIEMAELLQKRGYQTQYLAISDQKDIKVAAILYSVAMAGGLRMEINSGPVVADTT
YTTAFYKALQDYAKQQGALELVIKPYDTYQTFTGDGHPNDDEKPELIKALTKLNFTHDGLLTGYPNGEGDWHYVKELSGL
TSANLIKSFSKKGKALLKKAKTFGIKLHKLSRDELTQFKAITAATSSRRDYTDKSLSYYQDFYDSFGDSCEFMVATLNFD
DYLANLRHSQDRLKQGMAKLEADLAKNPRSEKKQNRLRELSSQFDTFQVRVAEAQELIIKYGKKDVPLAGSLFVYTPQEA
VYLFSGSYPEFNRFYAPALLQEHVMLRAIEKGISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYYPKPFKYKA
IKTIKALISRS
>Mature_410_residues
ALDIIDKETFGSFCSQVEYKSFIQSIEMAELLQKRGYQTQYLAISDQKDIKVAAILYSVAMAGGLRMEINSGPVVADTTY
TTAFYKALQDYAKQQGALELVIKPYDTYQTFTGDGHPNDDEKPELIKALTKLNFTHDGLLTGYPNGEGDWHYVKELSGLT
SANLIKSFSKKGKALLKKAKTFGIKLHKLSRDELTQFKAITAATSSRRDYTDKSLSYYQDFYDSFGDSCEFMVATLNFDD
YLANLRHSQDRLKQGMAKLEADLAKNPRSEKKQNRLRELSSQFDTFQVRVAEAQELIIKYGKKDVPLAGSLFVYTPQEAV
YLFSGSYPEFNRFYAPALLQEHVMLRAIEKGISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYYPKPFKYKAI
KTIKALISRS

Specific function: Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. Adds glycines 2 and 3 of the pentaglycine bridge, using glycyl- tRNA(Gly) as donor. Involved in resistance to methicillin [H]

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 46720; Mature: 46589

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDIIDKETFGSFCSQVEYKSFIQSIEMAELLQKRGYQTQYLAISDQKDIKVAAILYSV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
AMAGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELVIKPYDTYQTFTGDGHPND
HHCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
DEKPELIKALTKLNFTHDGLLTGYPNGEGDWHYVKELSGLTSANLIKSFSKKGKALLKKA
CCHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KTFGIKLHKLSRDELTQFKAITAATSSRRDYTDKSLSYYQDFYDSFGDSCEFMVATLNFD
HHHCEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECHH
DYLANLRHSQDRLKQGMAKLEADLAKNPRSEKKQNRLRELSSQFDTFQVRVAEAQELIIK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHH
YGKKDVPLAGSLFVYTPQEAVYLFSGSYPEFNRFYAPALLQEHVMLRAIEKGISCYNFLG
CCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMGEFDGSDGVLRFKQNFNGYITRKMGTFRYYPKPFKYKAIKTIKALISRS
HHCCCCCCCCEEEEECCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALDIIDKETFGSFCSQVEYKSFIQSIEMAELLQKRGYQTQYLAISDQKDIKVAAILYSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
AMAGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELVIKPYDTYQTFTGDGHPND
HHCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
DEKPELIKALTKLNFTHDGLLTGYPNGEGDWHYVKELSGLTSANLIKSFSKKGKALLKKA
CCHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
KTFGIKLHKLSRDELTQFKAITAATSSRRDYTDKSLSYYQDFYDSFGDSCEFMVATLNFD
HHHCEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECHH
DYLANLRHSQDRLKQGMAKLEADLAKNPRSEKKQNRLRELSSQFDTFQVRVAEAQELIIK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHH
YGKKDVPLAGSLFVYTPQEAVYLFSGSYPEFNRFYAPALLQEHVMLRAIEKGISCYNFLG
CCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMGEFDGSDGVLRFKQNFNGYITRKMGTFRYYPKPFKYKAIKTIKALISRS
HHCCCCCCCCEEEEECCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA