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The map label for this gene is murM [H]

Identifier: 195978424

GI number: 195978424

Start: 1354191

End: 1355405

Strand: Direct

Name: murM [H]

Synonym: Sez_1319

Alternate gene names: 195978424

Gene position: 1354191-1355405 (Clockwise)

Preceding gene: 195978423

Following gene: 195978425

Centisome position: 66.9

GC content: 43.13

Gene sequence:

>1215_bases
ATGTATACATATAAAATCGGAATTTCAGCTAAAGAGCACGATCAGTTTGTCCTATCACATCCTCAGGTCAATCTGCTGCA
AAGCGCTCATTGGGCTCAGGTAAAGGATAACTGGGAGCATGAGCTCATTGGCTTTTACCAAGATGACAAGCAAGTCGCTG
CTGCTGCTTGTCTGATCAAGAGACTGCCTCTAGGCATGACCATGATTTACATTCCTCGAGGGCCAATTATGGACTATTCT
GACTTTGAGTTGGTTAACTTTGTCATGACTAGCCTAAAGGCTTACGGTAAATCCAAGCGAGCCCTCTTGATTAAATGCGA
TCCTTCCTTGTTTATCAGTCAGGCCTTAATAGGTGAGGAAAGAAAAGACAATGACTTTACCCTCTCTACTATTGACTTTT
TAAAGACCATCGGTGTTGAGTGGGCTGGCAGGACCAAGGAACTTGAGCAAACGATTCAGCCCCGCTTTCAGGCCAATATT
TATGCCAAGGACTTTAAGCTCCAAAGCTTATCAAAAAAGGCCAGACAGTCTATCCGAACTGCTCAAAATAAGGGAGTCGA
GATTATTATTGGCTCAACAGAGCTACTTGAAGACTTCTCAGCACTGATGAAAAAGACCGAGGAGCGCAAACACATTTCTT
TGCGCGGCATTTCCTATTATGACAAATTAATGACCACTTACGCTAATCAGGCTTACATTACCATGGCCAGATTGAATCTT
CCCAAGCAAAAAACGCTCATACAGCAGCAATTAGAGGAAGTCTTAAGCAATCAGCAAGTCTTTACCCAAAACAGCAAGCC
AGGTAAGGTCGCAGAAAACCAAAATACCATTAAAAGGCTTGAAAGGGAGCTGGCTTTTCTAGATAAAGAAATACAAGCAG
GTAAAAGCATTGTACCTCTAGCAGCCACCCTGACGCTGATCTATGGGCGAACCTCTGAAAACCTATACGCAGGTATGGAT
AATGACTTTCGCCAATATCAGGCAGCTCTCTTAACCTGGTATCATACCGCAGAGGAGGCCTTTAAGCGCGGTTGTCAATG
GCACAATTTAGGAGGCGTTGAAAACCAATTAGATGGCGGACTGTTTCAGTTTAAAGCAAGATTAAACCCAGCTATCGAAG
AATTTGCAGGAGAATTCAGCATTCCAGTTGGACCTATCTCAAAAGTGGCCATGATAGCCTATAATCTGAGAAAAAAACTA
AGGAGTAACCCTTAA

Upstream 100 bases:

>100_bases
AAAATGGGGCTCCCGAGCTGAAAAAGCTGGCCAAATACATCACCAAATCAAACAATGACAGCGGCGTAGCGCATGCTATT
CGGAAGTGGGTATTAAACTA

Downstream 100 bases:

>100_bases
TGGCTTTAGATATCATTGACAAAGAAACCTTTGGCTCATTTTGCAGTCAAGTGGAGTATAAATCCTTCATTCAATCCATA
GAAATGGCAGAGCTGCTGCA

Product: putative peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme MurM

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIGFYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYS
DFELVNFVMTSLKAYGKSKRALLIKCDPSLFISQALIGEERKDNDFTLSTIDFLKTIGVEWAGRTKELEQTIQPRFQANI
YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGISYYDKLMTTYANQAYITMARLNL
PKQKTLIQQQLEEVLSNQQVFTQNSKPGKVAENQNTIKRLERELAFLDKEIQAGKSIVPLAATLTLIYGRTSENLYAGMD
NDFRQYQAALLTWYHTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMIAYNLRKKL
RSNP

Sequences:

>Translated_404_residues
MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIGFYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYS
DFELVNFVMTSLKAYGKSKRALLIKCDPSLFISQALIGEERKDNDFTLSTIDFLKTIGVEWAGRTKELEQTIQPRFQANI
YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGISYYDKLMTTYANQAYITMARLNL
PKQKTLIQQQLEEVLSNQQVFTQNSKPGKVAENQNTIKRLERELAFLDKEIQAGKSIVPLAATLTLIYGRTSENLYAGMD
NDFRQYQAALLTWYHTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMIAYNLRKKL
RSNP
>Mature_404_residues
MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIGFYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYS
DFELVNFVMTSLKAYGKSKRALLIKCDPSLFISQALIGEERKDNDFTLSTIDFLKTIGVEWAGRTKELEQTIQPRFQANI
YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGISYYDKLMTTYANQAYITMARLNL
PKQKTLIQQQLEEVLSNQQVFTQNSKPGKVAENQNTIKRLERELAFLDKEIQAGKSIVPLAATLTLIYGRTSENLYAGMD
NDFRQYQAALLTWYHTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMIAYNLRKKL
RSNP

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 46096; Mature: 46096

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIGFYQDDKQVAAAACLIK
CEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHEEEECCHHHHHHHHHHHH
RLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRALLIKCDPSLFISQALIGEE
HCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCC
RKDNDFTLSTIDFLKTIGVEWAGRTKELEQTIQPRFQANIYAKDFKLQSLSKKARQSIRT
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHCEEEEHHHHHHHHHHHHHHHHHH
AQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGISYYDKLMTTYANQAYITMARLNL
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHCCCCEEEEEECCC
PKQKTLIQQQLEEVLSNQQVFTQNSKPGKVAENQNTIKRLERELAFLDKEIQAGKSIVPL
CHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
AATLTLIYGRTSENLYAGMDNDFRQYQAALLTWYHTAEEAFKRGCQWHNLGGVENQLDGG
HHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCC
LFQFKARLNPAIEEFAGEFSIPVGPISKVAMIAYNLRKKLRSNP
CEEHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIGFYQDDKQVAAAACLIK
CEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCHHEEEECCHHHHHHHHHHHH
RLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRALLIKCDPSLFISQALIGEE
HCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCC
RKDNDFTLSTIDFLKTIGVEWAGRTKELEQTIQPRFQANIYAKDFKLQSLSKKARQSIRT
CCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHCEEEEHHHHHHHHHHHHHHHHHH
AQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGISYYDKLMTTYANQAYITMARLNL
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHCCCCEEEEEECCC
PKQKTLIQQQLEEVLSNQQVFTQNSKPGKVAENQNTIKRLERELAFLDKEIQAGKSIVPL
CHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
AATLTLIYGRTSENLYAGMDNDFRQYQAALLTWYHTAEEAFKRGCQWHNLGGVENQLDGG
HHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCC
LFQFKARLNPAIEEFAGEFSIPVGPISKVAMIAYNLRKKLRSNP
CEEHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA