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The map label for this gene is asd [H]

Identifier: 195978075

GI number: 195978075

Start: 990103

End: 991191

Strand: Direct

Name: asd [H]

Synonym: Sez_0948

Alternate gene names: 195978075

Gene position: 990103-991191 (Clockwise)

Preceding gene: 195978074

Following gene: 195978076

Centisome position: 48.91

GC content: 45.36

Gene sequence:

>1089_bases
ATGGGGTATACAGTAGCAGTGGTTGGAGCGACAGGCGCTGTCGGTCAGCAAATGATTAAGATGCTGGAGGAGTCAAGACT
GCCTATTTCAGCTATTAAATTATTAGCGTCTGCACGTTCAGCAGGAAAAATCCTCTCATTTAAGGGAGAGGATTTTGTTG
TTGAGGAGATAACAAAAGCAGCCTTCCAAGGCGTTGACCTAGCCCTTTTTTCAGCAGGAGGCAATGTTTCTACAAAGTAT
GTCCCTTATGCTGTTGCGGCAGGTGCTGTTGTGGTTGACAATACCTCTTATTTTCGTCAGCACCCAGCTGTTCCACTTGT
TGTTCCTGAGGTAAATGCTCATGCTCTTGATACACATCAAGGCCTTGTTGCTTGCCCTAATTGCTCTACGATTCAAATGA
TGATAGCGCTGGAGCCTATTCGTCAAAGGTGGGGTCTTGAGCGTATTATTGTTTCCACCTATCAGGCTGTTTCAGGTGCT
GGTCAATCAGCGATTCGTGAGACCCTAGCTCAGTATGACCAGGTTATTAACCAGGGCTTGTCTCCTAAGGAGGTGGAGGC
AAGTGTTTTACCGTCAGCTGGTGACAAGAGACATTATCCAATTGCTTTTAATGCTTTACCACAGATTGATCGTTTCACTG
AAAATGACTACACCTATGAAGAGATGAAAATGACAAATGAAACGAAAAAAATCATGGAGGACGATACGATTAAGGTGTCT
GCGACCTGTGTTCGTATACCCGTTTTATCAGCCCATTCAGAATCTATCTACATTGAAACCAAGGCAGTAGCTACTATCGA
AGCTGTTAAGGAGGCGATTGCACAATTTCCGGGTGCTGTTTTAGAGGACGATACAGGAGTGCAGCGATACCCACAGGCCG
TTAATGCTGTTGGTAGTCGTGAGACCTTTGTAGGAAGGCTTCGTAAGGATTTAGATGTTGAAAAGGGCATTCACATGTGG
GTGGTATCTGACAATTTGCTCAAGGGCGCAGCCTGGAATTCTGTTCAGATTGCAGAGACCCTGCACGAGCGTGGGCTTGT
CCAACCAGCACAGGACAATTTATTTGATTCTAGTGTCTCTTTTGACTGA

Upstream 100 bases:

>100_bases
TAGGCTTCTAGCTTAGCTTGCTTTTCTTTTGTGATGAAATAGGCTATAATAGGTCCAATATCATTTTTTGCAATATCATC
AGTTAAAGTGAGGTCGATCT

Downstream 100 bases:

>100_bases
TCATTCCTAAGAGGTATAGGAGCCTAATAGCTTGACAAATGATGAAAACATTTGCATAATGAATGTAAGCAATGAAACTA
AATGAAAAGAGGCGCTCTTA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGYTVAVVGATGAVGQQMIKMLEESRLPISAIKLLASARSAGKILSFKGEDFVVEEITKAAFQGVDLALFSAGGNVSTKY
VPYAVAAGAVVVDNTSYFRQHPAVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYTYEEMKMTNETKKIMEDDTIKVS
ATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQFPGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMW
VVSDNLLKGAAWNSVQIAETLHERGLVQPAQDNLFDSSVSFD

Sequences:

>Translated_362_residues
MGYTVAVVGATGAVGQQMIKMLEESRLPISAIKLLASARSAGKILSFKGEDFVVEEITKAAFQGVDLALFSAGGNVSTKY
VPYAVAAGAVVVDNTSYFRQHPAVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYTYEEMKMTNETKKIMEDDTIKVS
ATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQFPGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMW
VVSDNLLKGAAWNSVQIAETLHERGLVQPAQDNLFDSSVSFD
>Mature_361_residues
GYTVAVVGATGAVGQQMIKMLEESRLPISAIKLLASARSAGKILSFKGEDFVVEEITKAAFQGVDLALFSAGGNVSTKYV
PYAVAAGAVVVDNTSYFRQHPAVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGAG
QSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYTYEEMKMTNETKKIMEDDTIKVSA
TCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQFPGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWV
VSDNLLKGAAWNSVQIAETLHERGLVQPAQDNLFDSSVSFD

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=31.4868804664723, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=27.247191011236, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320362, Length=404, Percent_Identity=27.7227722772277, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39317; Mature: 39186

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYTVAVVGATGAVGQQMIKMLEESRLPISAIKLLASARSAGKILSFKGEDFVVEEITKA
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AFQGVDLALFSAGGNVSTKYVPYAVAAGAVVVDNTSYFRQHPAVPLVVPEVNAHALDTHQ
HHCCCCEEEEECCCCCCCEECCHHHHCCEEEECCCHHHHHCCCCEEEEECCCCEEEECCC
GLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGAGQSAIRETLAQYDQVINQGL
CEEECCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
SPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYTYEEMKMTNETKKIMEDDTIKVS
CCCHHHHHCCCCCCCCCCCCEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQFPGAVLEDDTGVQRYPQAVNAVGSR
EEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCH
ETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNSVQIAETLHERGLVQPAQDNLFDSSVS
HHHHHHHHHHCCHHCCCEEEEEECCHHCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCC
FD
CC
>Mature Secondary Structure 
GYTVAVVGATGAVGQQMIKMLEESRLPISAIKLLASARSAGKILSFKGEDFVVEEITKA
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AFQGVDLALFSAGGNVSTKYVPYAVAAGAVVVDNTSYFRQHPAVPLVVPEVNAHALDTHQ
HHCCCCEEEEECCCCCCCEECCHHHHCCEEEECCCHHHHHCCCCEEEEECCCCEEEECCC
GLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGAGQSAIRETLAQYDQVINQGL
CEEECCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
SPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYTYEEMKMTNETKKIMEDDTIKVS
CCCHHHHHCCCCCCCCCCCCEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQFPGAVLEDDTGVQRYPQAVNAVGSR
EEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCH
ETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNSVQIAETLHERGLVQPAQDNLFDSSVS
HHHHHHHHHHCCHHCCCEEEEEECCHHCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCC
FD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2434499; 12397186 [H]