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The map label for this gene is cdd [H]

Identifier: 195978062

GI number: 195978062

Start: 972966

End: 973355

Strand: Direct

Name: cdd [H]

Synonym: Sez_0935

Alternate gene names: 195978062

Gene position: 972966-973355 (Clockwise)

Preceding gene: 195978061

Following gene: 195978063

Centisome position: 48.07

GC content: 44.62

Gene sequence:

>390_bases
ATGGAGGCTACTGATTTAGTTTCGTTAGCCATTGAAGCTAGTAAAAGGGCTTATGTGCCTTACTCACATTTCCCGATCGG
AGCTGCTTTAAAGACAAAGGACGGAACAATCTATACTGGCTGTAATATCGAGAATGCCAGCTTTGGCTTGACCAATTGTG
GGGAGCGAACAGCTATTTTTAAGGCTGTTTCTGAGGGACATCAGCAGCTTTTAGAAATTGCCATTTATGGAGAGACTGAT
GAGCCAATCTCTCCTTGTGGGGCCTGTCGTCAGGTCATGGCAGAATTTTTTGAAGCCACTGCTCCAGTAACGCTAATTGC
TAAGGACGGTCGTACCATGCGCACAACTGTTGGCGAGTTACTTCCTTATTCGTTTACAGATTTATCGTAA

Upstream 100 bases:

>100_bases
GGTGCTCGTTCTCTAGAGGACGCTTTAGCTTTTGTCGAAGCAGGAGCTACACGTATTGGAACTTCTGCAGGGGTAACGAT
TATGAAAGGTGAAGTTGCCA

Downstream 100 bases:

>100_bases
TCTGGCTTAATTTTGTTATCTAGCCATTAGGCTTTATATTTACTTTCGGCAATTGGTTTGCTAGAAATATTTTTAGGAGG
GTTCATATTCATGAACAAGA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGCNIENASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETD
EPISPCGACRQVMAEFFEATAPVTLIAKDGRTMRTTVGELLPYSFTDLS

Sequences:

>Translated_129_residues
MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGCNIENASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETD
EPISPCGACRQVMAEFFEATAPVTLIAKDGRTMRTTVGELLPYSFTDLS
>Mature_129_residues
MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGCNIENASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETD
EPISPCGACRQVMAEFFEATAPVTLIAKDGRTMRTTVGELLPYSFTDLS

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=55.7377049180328, Blast_Score=126, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=49.1803278688525, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17551074, Length=121, Percent_Identity=46.2809917355372, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=119, Percent_Identity=38.655462184874, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24582741, Length=127, Percent_Identity=43.3070866141732, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19920920, Length=137, Percent_Identity=43.0656934306569, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582744, Length=142, Percent_Identity=35.2112676056338, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13917; Mature: 13917

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGCNIENASFGLTNCGERTAIF
CCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCHHHHH
KAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAPVTLIAKDGRTMRTTVGEL
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
LPYSFTDLS
CCCCCCCCC
>Mature Secondary Structure
MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGCNIENASFGLTNCGERTAIF
CCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCHHHHH
KAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAPVTLIAKDGRTMRTTVGEL
HHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
LPYSFTDLS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]