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The map label for this gene is atpB

Identifier: 195977922

GI number: 195977922

Start: 827093

End: 827809

Strand: Direct

Name: atpB

Synonym: Sez_0793

Alternate gene names: 195977922

Gene position: 827093-827809 (Clockwise)

Preceding gene: 195977921

Following gene: 195977923

Centisome position: 40.86

GC content: 38.77

Gene sequence:

>717_bases
ATGGAAGAAGCTAAAGTACCGATGGTAGAGCTTGGTCCAATAACCTTTAATTTGACCCTACTTGCTGTTTGTATTGTTAC
TATCCTACTGATATTTGGCTTTGTTTTTTGGGCAAGTCGTCAGATGACATTAAAACCAAAAGGCAAGCAAACTGCGTTAG
AATATTTAATCAGCTTTGTTAATGGTATTGGGGAAGAGCATTTGGATAGTCATCTTCAGAAGTCTTATTCGCTTTTACTT
TTTACCATTTTTCTTTTTGTGGCAGTTGCCAACAACCTAGGCTTATTTACAAAGCTAGAAACAACCAGTGGCTACAACCT
ATGGACATCGCCAACAGCTAATTTGGCCTTTGACCTAGCCCTATCTCTGTTTGTGACGCTTCTTGTTCATATCGAAGGCA
TTAGACGTCGTGGTTTTGGCGCTTATTTAAAACGCTTTGCGACACCTTGGCCAATGACTCCGATGAACCTATTAGAAGAA
TTTACCAACTTCCTATCACTTGCTATCAGGCTGTTTGGTAATATCTTTGCAGGAGAGGTTGTGACAGGCTTGATTGTTCA
GCTGGCCAATTATCGCCTGTATTGGTGGCCAATTGCTTTCCTTGTTAATATAGCATGGACAGCCTTTTCCATATTTATTT
CCTGCATACAAGCCTTTGTATTTACAAAATTAACAGCAACGTATTTAGGAAAAAAAGTTAATGAATCAGAAGAATAA

Upstream 100 bases:

>100_bases
CCTAGGTGTTGCCTTTATTGAAGGTACCTTCTTCGTTACCCTTGTTATGGCCTTCATTCTAAAATAACAGCCTATTTGAT
ATAGAAAAGGAGGGTATTAA

Downstream 100 bases:

>100_bases
GAAGGGAGGACAAACGAATGTCAGTTACAATTGGTGAGCTCATTGGGAATTTTATTCTGGTAACAGGCTCTGTCATCGTC
TTGTTGCTCTTGATTAAAGC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTLKPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLL
FTIFLFVAVANNLGLFTKLETTSGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQAFVFTKLTATYLGKKVNESEE

Sequences:

>Translated_238_residues
MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTLKPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLL
FTIFLFVAVANNLGLFTKLETTSGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQAFVFTKLTATYLGKKVNESEE
>Mature_238_residues
MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTLKPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLL
FTIFLFVAVANNLGLFTKLETTSGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQAFVFTKLTATYLGKKVNESEE

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=213, Percent_Identity=30.9859154929577, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_STRE4 (C0M715)

Other databases:

- EMBL:   FM204883
- RefSeq:   YP_002746245.1
- EnsemblBacteria:   EBSTRT00000066544
- GeneID:   7695881
- GenomeReviews:   FM204883_GR
- KEGG:   seu:SEQ_0916
- GeneTree:   EBGT00050000028075
- OMA:   LHGQVFL
- ProtClustDB:   PRK05815
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 26902; Mature: 26902

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x139725c8)-; HASH(0x1b3316b8)-; HASH(0x1aff658c)-; HASH(0x194623a4)-; HASH(0x1a08a328)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTLKPKGKQTALEYLISFV
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHH
NGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETTSGYNLWTSPTANLAFDLA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCCHHHHHHHH
LSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEV
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQAFVFTKLTATYLGKKVNESEE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTLKPKGKQTALEYLISFV
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHH
NGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETTSGYNLWTSPTANLAFDLA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCCHHHHHHHH
LSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEEFTNFLSLAIRLFGNIFAGEV
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQAFVFTKLTATYLGKKVNESEE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA