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The map label for this gene is aroA [H]

Identifier: 195977832

GI number: 195977832

Start: 727400

End: 728683

Strand: Direct

Name: aroA [H]

Synonym: Sez_0700

Alternate gene names: 195977832

Gene position: 727400-728683 (Clockwise)

Preceding gene: 195977831

Following gene: 195977833

Centisome position: 35.94

GC content: 46.18

Gene sequence:

>1284_bases
ATGAAATTAAGAACAAAAGCTAAGGCGCTTAGGGGACGTCTAAGGGTACCAGGTGACAAGTCAATTAGCCATCGTGCAGT
CATCTTTGGTGCTATAGCAGAGGGGCAAACGGTGATTCATGGTCTTTTAAGGGGGCAAGATGTTTTAGCCACCATTCAAG
CCTTTCGAGACCTAGGTGTCACCATTTACGAGTCAGCTGATAGCTTGATCATTGAAGGAAGAGGCTTTAAAGGCCTAAAG
CCAGCTCAAAAGCCTCTAGACATGGGAAATTCAGGTACTTCTATGCGCCTGCTTGCAGGGCTATTAGCAGCACAGGATTT
TTCGGTGCAGCTGTTTGGAGATGATAGCCTATCAAGGCGTCCTATGGATCGTATTACCATACCATTGTCTCTAATGGGAG
CAGAGCTATCTGGTCAAGGAGAAAAAGAGCTTCCACCACTGATTGTAAAAGGCTGTCAGGGCTTGCGGCCAATCCATTAT
CAACTGCCTGTGGCGTCTGCTCAGGTCAAGTCTGCTATTTTATTAGCTGCTTTGCAGACACAGGGAGAGACTGTTATCCT
TGAAAAGGAATTGACAAGAAATCATACCGAAGAGATGATTGAACAATTTGGAGGAAAGCTCTCAGTAGCTGGAAAGCAAA
TCAGTATCAAAGGACCGCAGCGTTTGCAGGGACAGACCTTACAGATTCCTGGCGATCTCTCTAGCGCAGCCTTTTGGTTA
GCTGCTGGTCTGATTGTTCCGGGGTCAGATCTTGTGCTCGAAAATGTAGGAATTAATCCTACGCGGACAGGTCTTTTGGA
GGTTATTGAGAAAATGGGCGGCCAGCTTTCTTATCAGGCTGTTGATAAGGATATACAGACTGCTACCCTAAAAGTGTCTT
ATTCCACCCTAAAGGGCATTGAGATTTCTGGTGACTTGATTCCTCGCTTGATTGACGAATTGCCTGTCATTGCTTTGCTG
GCAACTCAGGCACAGGGAACGACTTATATCAGGGACGCTCAAGAATTACGGGTCAAGGAAACTGACCGCATTCAGGCTGT
TACTGATGTATTAGGACAGATGGGTGCTGATATTCAGGCGACAGAGGACGGTATGGTGATTAGAGGCAAAACACCATTAC
ATGGTGCAGCTGTCAGTACCTGTGGAGATCATAGAATTGGCATGATGACAGCTATTGCAGCCCTACTGGTTGAAGAAGGA
CAGGTCACCCTAGAGCGAGCAGAAGCTATCCTGACTTCTTATCCTGACTTTTTTAAGGATTTAGAGAGGTTATGGCATGA
CTAA

Upstream 100 bases:

>100_bases
TTGGTGATTAGTTGATGGGGTAAGGGCCCTTGTCCTTACTTCATTTTCTTTTATTTGCTTTGCTGAGCCGATGCTGGTAT
GCTAAAAGACAGGAGTAGTG

Downstream 100 bases:

>100_bases
GCTGCTATTAGGATTTATGGGAGTTGGCAAGACGACAGTTGCAGCCCAATTAGATGAGCATTTTTTGGATATGGATAGGC
TTATTGAGGCTAAAATAGGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKLRTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLK
PAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLFGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHY
QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWL
AAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQLSYQAVDKDIQTATLKVSYSTLKGIEISGDLIPRLIDELPVIALL
ATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQATEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEG
QVTLERAEAILTSYPDFFKDLERLWHD

Sequences:

>Translated_427_residues
MKLRTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLK
PAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLFGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHY
QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWL
AAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQLSYQAVDKDIQTATLKVSYSTLKGIEISGDLIPRLIDELPVIALL
ATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQATEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEG
QVTLERAEAILTSYPDFFKDLERLWHD
>Mature_427_residues
MKLRTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLK
PAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLFGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHY
QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWL
AAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQLSYQAVDKDIQTATLKVSYSTLKGIEISGDLIPRLIDELPVIALL
ATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQATEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEG
QVTLERAEAILTSYPDFFKDLERLWHD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=424, Percent_Identity=30.188679245283, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=429, Percent_Identity=26.5734265734266, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46024; Mature: 46024

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGV
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEHHCCHHHHHHHHCCHHHHHHHHHHHHCCE
TIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLFGDDSLSRR
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCC
PMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHYQLPVASAQVKSAILLAALQT
CCHHEEEEHHEECCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHC
QGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWL
CCCEEEEEHHHHHHHHHHHHHHHCCEEEECCCEEEECCCCCCCCCEEECCCCCHHHHHHH
AAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQLSYQAVDKDIQTATLKVSYSTLKGI
HHCEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEHHHHCCCCEEEEEEEEHHHHCCE
EISGDLIPRLIDELPVIALLATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQA
EECHHHHHHHHHHCCEEEEEEECCCCCEEECCHHHHCCCHHHHHHHHHHHHHHHCCCCEE
TEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEGQVTLERAEAILTSYPDFFKD
CCCCEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
LERLWHD
HHHHHCC
>Mature Secondary Structure
MKLRTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGV
CCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEHHCCHHHHHHHHCCHHHHHHHHHHHHCCE
TIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLFGDDSLSRR
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCC
PMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHYQLPVASAQVKSAILLAALQT
CCHHEEEEHHEECCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHC
QGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWL
CCCEEEEEHHHHHHHHHHHHHHHCCEEEECCCEEEECCCCCCCCCEEECCCCCHHHHHHH
AAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQLSYQAVDKDIQTATLKVSYSTLKGI
HHCEECCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEHHHHCCCCEEEEEEEEHHHHCCE
EISGDLIPRLIDELPVIALLATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQA
EECHHHHHHHHHHCCEEEEEEECCCCCEEECCHHHHCCCHHHHHHHHHHHHHHHCCCCEE
TEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEGQVTLERAEAILTSYPDFFKD
CCCCEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
LERLWHD
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA