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The map label for this gene is aroK

Identifier: 195977833

GI number: 195977833

Start: 728676

End: 729170

Strand: Direct

Name: aroK

Synonym: Sez_0701

Alternate gene names: 195977833

Gene position: 728676-729170 (Clockwise)

Preceding gene: 195977832

Following gene: 195977834

Centisome position: 36.0

GC content: 40.0

Gene sequence:

>495_bases
ATGACTAAGCTGCTATTAGGATTTATGGGAGTTGGCAAGACGACAGTTGCAGCCCAATTAGATGAGCATTTTTTGGATAT
GGATAGGCTTATTGAGGCTAAAATAGGCATGAGCATATCAGCATTTTTTTCCTATCGTGGTGAAGCAGCCTTTAGAAAAC
TTGAGTCAGATACCTTACAGGAAGTGCTGGCACTTGATAATGAGACTATCGTATCAACTGGTGGAGGTGTTGTCCTTAGT
AAGGCAAACCGAGAATTAATCAGAAAAAATCACAAACATAATATCCTCTTAACAGCCTCCTTTGAGGTTTTGTATGACAG
GCTTAAAAAAGATAGGCTGTGCCAAAGACCACTGTTTTTAAACCATTCTAAAGCAGAATTCTATGCTATTTTTCAGCAGC
GCATGGCCTTGTATGAGGGATTGGCAGACAAAGTGATTAATGTTGAGCATAGGACACCAAAGGAGGTTGCAGCAATCATT
GCCAATATGTCGTAA

Upstream 100 bases:

>100_bases
GCAGCCCTACTGGTTGAAGAAGGACAGGTCACCCTAGAGCGAGCAGAAGCTATCCTGACTTCTTATCCTGACTTTTTTAA
GGATTTAGAGAGGTTATGGC

Downstream 100 bases:

>100_bases
CTGCTGAGGATTAGACTTTTAGCCTCCTATTCGCAGCCCAGCTTTTCTTAATGATTAGGTATGAAAAGCTAATAATAGGA
TGAAATAAAGTTGAATTCTA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFSYRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLS
KANRELIRKNHKHNILLTASFEVLYDRLKKDRLCQRPLFLNHSKAEFYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
ANMS

Sequences:

>Translated_164_residues
MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFSYRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLS
KANRELIRKNHKHNILLTASFEVLYDRLKKDRLCQRPLFLNHSKAEFYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
ANMS
>Mature_163_residues
TKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFSYRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSK
ANRELIRKNHKHNILLTASFEVLYDRLKKDRLCQRPLFLNHSKAEFYAIFQQRMALYEGLADKVINVEHRTPKEVAAIIA
NMS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI1786587, Length=166, Percent_Identity=28.3132530120482, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_STREM (B4U247)

Other databases:

- EMBL:   CP001129
- RefSeq:   YP_002123077.1
- EnsemblBacteria:   EBSTRT00000010175
- GeneID:   6761642
- GenomeReviews:   CP001129_GR
- KEGG:   sez:Sez_0701
- GeneTree:   EBGT00050000027776
- HOGENOM:   HBG335815
- OMA:   MSISAFF
- ProtClustDB:   PRK00131
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 18518; Mature: 18387

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 28-28 BINDING 52-52 BINDING 75-75 BINDING 116-116 BINDING 134-134 BINDING 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFSYRGEAAFRKLESDTLQ
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
EVLALDNETIVSTGGGVVLSKANRELIRKNHKHNILLTASFEVLYDRLKKDRLCQRPLFL
HHHHCCCCEEEECCCCEEEECCCHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
NHSKAEFYAIFQQRMALYEGLADKVINVEHRTPKEVAAIIANMS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFSYRGEAAFRKLESDTLQ
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
EVLALDNETIVSTGGGVVLSKANRELIRKNHKHNILLTASFEVLYDRLKKDRLCQRPLFL
HHHHCCCCEEEECCCCEEEECCCHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
NHSKAEFYAIFQQRMALYEGLADKVINVEHRTPKEVAAIIANMS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA