Click here to switch to the map view.

The map label for this gene is lldR [H]

Identifier: 195977821

GI number: 195977821

Start: 713361

End: 714032

Strand: Direct

Name: lldR [H]

Synonym: Sez_0687

Alternate gene names: 195977821

Gene position: 713361-714032 (Clockwise)

Preceding gene: 195977820

Following gene: 195977822

Centisome position: 35.24

GC content: 43.15

Gene sequence:

>672_bases
ATGGCTAGGCCTTTAGTCGAAAAAACAGCAGAGCGCTTGTTAAAGCTAATTTTAGAACGGGGATATGAGGTTGGAGCAAA
GCTCCCCAATGAATATGAGTTAGCACAGGACTTAGAGGTTGGAAGAAGCACTATTAGAGAAGCTGTTAGAAGCTTAGCAA
CTAGAAATGTTTTAGAGGTTAGACAAGGATCAGGTACTTATATTAGCTCGAAAAAAGGTGTTTCTGAGGATCCTTTAGGC
TTTTCCTTAGTCAAGGACACAGCCAAGCTGACCGCTGATTTGTTTGAATTGCGGCTGTTGCTTGAGCCTAGGATTGCCGC
TTTGACAGCACAGCACGCAACGCCAAAGGAGGTTGAAGCCTTAGAGAAGCTTGTTATTGATATTGAAGAAGCGGTGGCTG
CTGGTGACCCTAAGCACTTGCAGCTGGATGTGAATTTTCATTCCTTGATGGCAAAATACAGCGGTAATATTGCTATGGAT
AGCCTGCTGCCAGTGATTAATCAGTCGATTCATCTGATCAATGCCAATTACACAAATCGTCAGATGAAAGAAGATTCTCT
ACAAGCCCACAGAGATATTTTGAATGCGATTAAAGCAGGAGATCCCGTTGCAGCACATGACGCTATGCTTTTGCATATCA
TGACCGTTAAGCGAACTGCATTTCTATCGTAA

Upstream 100 bases:

>100_bases
TTGGTTTGTTTAAAGAACGTTGGAATACCATTCCCCACTACAATTATAAAAAGAAATAGTGTACAATAGTAGCTAGCAAT
AAGTAGGAAGAAGGGATTGT

Downstream 100 bases:

>100_bases
GTTTAGGCTTTCTTGATGGATACAGCCAAGTGCAGCCTTTTGGGTTTTAACTGATTTATTTGATGGCTTAGATAAGAAGG
CTTGGTCTTAGAGATACTAG

Product: putative L-lactate dehydrogenase operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRSTIREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLG
FSLVKDTAKLTADLFELRLLLEPRIAALTAQHATPKEVEALEKLVIDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPVAAHDAMLLHIMTVKRTAFLS

Sequences:

>Translated_223_residues
MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRSTIREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLG
FSLVKDTAKLTADLFELRLLLEPRIAALTAQHATPKEVEALEKLVIDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPVAAHDAMLLHIMTVKRTAFLS
>Mature_222_residues
ARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRSTIREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGF
SLVKDTAKLTADLFELRLLLEPRIAALTAQHATPKEVEALEKLVIDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMDS
LLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPVAAHDAMLLHIMTVKRTAFLS

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=230, Percent_Identity=31.7391304347826, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=28.3185840707965, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789621, Length=236, Percent_Identity=24.5762711864407, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786303, Length=215, Percent_Identity=31.6279069767442, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=28.6343612334802, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI48994955, Length=217, Percent_Identity=26.2672811059908, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24643; Mature: 24512

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRSTIREAVRSLATRNVLEV
CCCCHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLEPRIAALTAQHATPKEVEA
HCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHH
LEKLVIDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMDSLLPVINQSIHLINANYTNR
HHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCH
QMKEDSLQAHRDILNAIKAGDPVAAHDAMLLHIMTVKRTAFLS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRSTIREAVRSLATRNVLEV
CCCHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLEPRIAALTAQHATPKEVEA
HCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHH
LEKLVIDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMDSLLPVINQSIHLINANYTNR
HHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCH
QMKEDSLQAHRDILNAIKAGDPVAAHDAMLLHIMTVKRTAFLS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]