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The map label for this gene is yesM [H]

Identifier: 195977700

GI number: 195977700

Start: 587665

End: 589383

Strand: Direct

Name: yesM [H]

Synonym: Sez_0562

Alternate gene names: 195977700

Gene position: 587665-589383 (Clockwise)

Preceding gene: 195977699

Following gene: 195977701

Centisome position: 29.03

GC content: 43.98

Gene sequence:

>1719_bases
ATGAAGCGCTACCCTCTTTTAGTACAATTAGTGAGTTATTTTTTTCTGATTGTGATTTCACTAATCACTATTCTGGGAGT
GATTTATTATCAGACCAGCTCTCATAATATCAGGCAGCTCATTGAACGTGAAACAAGACAGAGCATTCGGCAGAGCTCAC
AATTTATTGATGCTTACATTAAGCCTTTGAAGGAGACAACCTCAGCCTTGGCTAATCATACGAGCATTCAGGCCTTTGCT
AAGGACGCTAACAGTAATGATCAAAGCCAGGTATTGGCATTGATGACAACTGTGCTGTCGACCAATTCGGACTTGCTCTC
TGCGGTTTTAGTGACAAAGGACGGTCGTATGGTAACAACCAATCCGAAGCTAACCATGACCACCTCACACGATATGATGG
CAGAGCTCTGGTACAAGTCAGCCATTGATCGTAAGGCCATGCCTGTCTTGACTCCTGCAAGGCAGCTATCCTCACATTCT
AAAAAGGACTGGGTGGTCTCTGTGACCCAAGAGGTTGTGGATCAAGCAGGTAACAATCTGGGGGTGCTGCGGCTAGATAT
TGGCTACAATACCATCAAATCCTCCCTAGATCAATTGCAGCTTGGGCGTAAGGGCTTTGCTTTTATTGTTAATGATAAGC
ATGAATTTGTCTATCACCCTAAAAATACCGTCTATAGCTCAGAGCGAGAAATGGCCGCAATGAAGCCCTACCTTGCTGTT
GCTGATGGCTATACAAAGCCTAAGGATTATTTTGTTTACCAAAGGGTGATTCCAGACAGTCAATGGACCTTGATTGGAGT
TGCCTCTTTGGATCAGCTGTATCATGTGCAAAGGCAGATTTTTTGGTCCTTTTTAGGGACGGGGCTGCTTGCAACTATCA
TCTGTGGTCTTGGAACAGTATTTGTTCTGAGAAGCTGGATTGGTCCTATTAGGAGGCTTCAGGCTCTCATTTTAGCTATT
CAAAAGGGTAACCGTCAGCTGCGTGCTGAGGAAACTGGCTCGCCTGAGTTAGCTGATTTGGCACGTCAGTTTAATGCCAT
GCTGGATCAAATTGATAGCCTTATGGTATCAGTGGCCGACAAGGAAAAAGCCATTGGGCAGTATCGTCTGCAAGCCTTAG
CCAGCCAAATTAACCCTCATTTTTTGTACAACACCTTAGATACTATTATTTGGATGGCAGAGTTTAATGACAGCCAGCGT
GTAGTTGATGTCACCAAGTCTCTGGCTAAGTATTTCCGCTTGGCCTTAAATCAGGGAAATGAATTCATTAGCCTTGCTGA
TGAATTGGATCACGCTCGTCAGTATTTGTTTATACAAAAGCAGCGCTATGGTGAGAAGCTGCACTATGAGATCAAGGGGC
TTGAGAAATATCAGGACTTTATGATTCCTAAGCTGATTCTTCAGCCCTTGGTGGAAAACGCCATTTATCATGGTATTAAG
GAGGTTGATAGACCTGGAATGATCAGAGTAACTGTATTAGAAGCTGATCGTCATGTGATATTATCCGTTTGGGATAATGG
AAAGGGCATAAGCTTAGTTGATGACAGCAGTCAGGCCCTGCTTGAGCGTGGCGGTGTTGGTTTAAAAAATGTTGACCAGC
GCTTGAAATTACAGTATGGTCATCTCTATAGAATGGCAATCACTAGCGAGCAGGCTGTTTTTACTGAGATTAAGCTTTAT
CTTCCCAAGCCGCTTGATGGCCTAAATGAGCTCCCCTAA

Upstream 100 bases:

>100_bases
TAGCAGAGCAGGTTGGCTTTGAGGATATTAATTATTTTTCCCAGCGCTTTAAGCAGTTGGTTGGAACGACACCAAGGCAA
TATAAAAAAGGAGAAGGCCA

Downstream 100 bases:

>100_bases
TCAATCTGCCCTTAGTAGCAACAAGGAAAAGAGAGGTTTATGTCTTTAGAATCCGATTATTTTAAGCGAAAAAGTCCTGT
ATTTGAGGCCCTTATCCCTT

Product: two-component sensor kinase YesM-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERETRQSIRQSSQFIDAYIKPLKETTSALANHTSIQAFA
KDANSNDQSQVLALMTTVLSTNSDLLSAVLVTKDGRMVTTNPKLTMTTSHDMMAELWYKSAIDRKAMPVLTPARQLSSHS
KKDWVVSVTQEVVDQAGNNLGVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVYHPKNTVYSSEREMAAMKPYLAV
ADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHVQRQIFWSFLGTGLLATIICGLGTVFVLRSWIGPIRRLQALILAI
QKGNRQLRAEETGSPELADLARQFNAMLDQIDSLMVSVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQR
VVDVTKSLAKYFRLALNQGNEFISLADELDHARQYLFIQKQRYGEKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIK
EVDRPGMIRVTVLEADRHVILSVWDNGKGISLVDDSSQALLERGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLY
LPKPLDGLNELP

Sequences:

>Translated_572_residues
MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERETRQSIRQSSQFIDAYIKPLKETTSALANHTSIQAFA
KDANSNDQSQVLALMTTVLSTNSDLLSAVLVTKDGRMVTTNPKLTMTTSHDMMAELWYKSAIDRKAMPVLTPARQLSSHS
KKDWVVSVTQEVVDQAGNNLGVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVYHPKNTVYSSEREMAAMKPYLAV
ADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHVQRQIFWSFLGTGLLATIICGLGTVFVLRSWIGPIRRLQALILAI
QKGNRQLRAEETGSPELADLARQFNAMLDQIDSLMVSVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQR
VVDVTKSLAKYFRLALNQGNEFISLADELDHARQYLFIQKQRYGEKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIK
EVDRPGMIRVTVLEADRHVILSVWDNGKGISLVDDSSQALLERGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLY
LPKPLDGLNELP
>Mature_572_residues
MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERETRQSIRQSSQFIDAYIKPLKETTSALANHTSIQAFA
KDANSNDQSQVLALMTTVLSTNSDLLSAVLVTKDGRMVTTNPKLTMTTSHDMMAELWYKSAIDRKAMPVLTPARQLSSHS
KKDWVVSVTQEVVDQAGNNLGVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVYHPKNTVYSSEREMAAMKPYLAV
ADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHVQRQIFWSFLGTGLLATIICGLGTVFVLRSWIGPIRRLQALILAI
QKGNRQLRAEETGSPELADLARQFNAMLDQIDSLMVSVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQR
VVDVTKSLAKYFRLALNQGNEFISLADELDHARQYLFIQKQRYGEKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIK
EVDRPGMIRVTVLEADRHVILSVWDNGKGISLVDDSSQALLERGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLY
LPKPLDGLNELP

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=204, Percent_Identity=32.3529411764706, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788723, Length=226, Percent_Identity=33.1858407079646, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64974; Mature: 64974

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERETRQSIRQSSQFIDAYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLKETTSALANHTSIQAFAKDANSNDQSQVLALMTTVLSTNSDLLSAVLVTKDGRMVTT
HHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHEEECCCEEEEC
NPKLTMTTSHDMMAELWYKSAIDRKAMPVLTPARQLSSHSKKDWVVSVTQEVVDQAGNNL
CCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCE
GVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVYHPKNTVYSSEREMAAMKPYLAV
EEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHCCHHEE
ADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHVQRQIFWSFLGTGLLATIICGLGTV
CCCCCCCHHHEEEHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLRSWIGPIRRLQALILAIQKGNRQLRAEETGSPELADLARQFNAMLDQIDSLMVSVAD
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQRVVDVTKSLAKYFRLALNQGN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
EFISLADELDHARQYLFIQKQRYGEKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIK
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDRPGMIRVTVLEADRHVILSVWDNGKGISLVDDSSQALLERGGVGLKNVDQRLKLQYG
HCCCCCEEEEEEEECCCEEEEEEECCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHC
HLYRMAITSEQAVFTEIKLYLPKPLDGLNELP
CEEEEEECCCHHHHHHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERETRQSIRQSSQFIDAYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLKETTSALANHTSIQAFAKDANSNDQSQVLALMTTVLSTNSDLLSAVLVTKDGRMVTT
HHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHEEECCCEEEEC
NPKLTMTTSHDMMAELWYKSAIDRKAMPVLTPARQLSSHSKKDWVVSVTQEVVDQAGNNL
CCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCE
GVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVYHPKNTVYSSEREMAAMKPYLAV
EEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHCCHHEE
ADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHVQRQIFWSFLGTGLLATIICGLGTV
CCCCCCCHHHEEEHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLRSWIGPIRRLQALILAIQKGNRQLRAEETGSPELADLARQFNAMLDQIDSLMVSVAD
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQRVVDVTKSLAKYFRLALNQGN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
EFISLADELDHARQYLFIQKQRYGEKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIK
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDRPGMIRVTVLEADRHVILSVWDNGKGISLVDDSSQALLERGGVGLKNVDQRLKLQYG
HCCCCCEEEEEEEECCCEEEEEEECCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHC
HLYRMAITSEQAVFTEIKLYLPKPLDGLNELP
CEEEEEECCCHHHHHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]