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The map label for this gene is paaG [C]

Identifier: 195977547

GI number: 195977547

Start: 433621

End: 434481

Strand: Direct

Name: paaG [C]

Synonym: Sez_0404

Alternate gene names: 195977547

Gene position: 433621-434481 (Clockwise)

Preceding gene: 195977546

Following gene: 195977548

Centisome position: 21.42

GC content: 43.67

Gene sequence:

>861_bases
TTGATTGTCAAATTATTTGGTCATAAAATTATTTGTTCATCAAATAAGCTGTCAGAAAAGAGGAGTGATATGACGTTTCA
AAATATCATTTTTGAGCTTGAAGAGGATTTGGCCATTTTAACCTTAAATCGTCCAGAGGTTTCTAATGGCTTTAATATTC
CAGCCTGTCAGGAGATTCTTGAGGCTATCCAGTTGGTTAAGGATAATCCCTCTTTGCGCTTTTTAGTGATTAAGGCAAAG
GGTAAGGTCTTTTCAGTCGGTGGTGACTTGGTTGAGATGCAAAATGCTGTTGAAAGAGATGATGTCCAGTCTCTGGTCAA
GATTGCTGAGCTGGTTCAGGACATTTCCTTTGCTATCAAGCAATTGCCAAAGCCTGTTATCCTCTGTGCTGATGGTGCGG
TGGCTGGTGCGGCCTTTAATATTGCCTTAGCGGTGGATTTTTGTATTGCTAGCACCCAGACAAAATTTATTCAGGCCTTT
GTTAATGTCGGCTTAGCGCCAGATGCAGGCGGTCTTTTCTTGTTAACACGTGCCGTTGGCCTAAATAGAGCGACTCATCT
GGTGATGACCGGTGAGGGGGTGACAGCAGAAAAAGGGCTTGAGTACGGATTTGTCTATCGAGCTGCTGAGTCAGATAAGC
TTGATAAGACCTGTAGTCAGCTGTTAAAGCGTTTGAGGCGTGGGTCTTCAAATTCCTACGCCGGCATGAAATCTTTGGTA
TGGCAAAGCTTTTTTGCAGGTTGGGAGGATTATGCTCAAAAAGAGCTTGCTATTCAAGAGGAATTGGCCTTTAAGGAGGA
CTTTAAAGAGGGCGTCAGGGCTTATGGAGATAGGAGGCGGCCAAATTTTCAGGGGAAATAG

Upstream 100 bases:

>100_bases
AACTGAACTTTTTAAATTGCGTATATAATTTTAATGTATTTTTTACAATCTTTTTCTTGCATAACGACTGATTCTAGTGT
ACTATAGTCTAGTAATTAAT

Downstream 100 bases:

>100_bases
CTCTTATGTGCTTGCAAAATACTTTGATGTCTGATATACTTTGAAAATCAAAGTATTTTACAGCTAGGGAGGTGTTTACT
TGGAATATAATAAGATTAAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MIVKLFGHKIICSSNKLSEKRSDMTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIQLVKDNPSLRFLVIKAK
GKVFSVGGDLVEMQNAVERDDVQSLVKIAELVQDISFAIKQLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAF
VNVGLAPDAGGLFLLTRAVGLNRATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLV
WQSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFQGK

Sequences:

>Translated_286_residues
MIVKLFGHKIICSSNKLSEKRSDMTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIQLVKDNPSLRFLVIKAK
GKVFSVGGDLVEMQNAVERDDVQSLVKIAELVQDISFAIKQLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAF
VNVGLAPDAGGLFLLTRAVGLNRATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLV
WQSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFQGK
>Mature_286_residues
MIVKLFGHKIICSSNKLSEKRSDMTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIQLVKDNPSLRFLVIKAK
GKVFSVGGDLVEMQNAVERDDVQSLVKIAELVQDISFAIKQLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAF
VNVGLAPDAGGLFLLTRAVGLNRATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLV
WQSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFQGK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=266, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI31542718, Length=243, Percent_Identity=24.2798353909465, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI70995211, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787660, Length=263, Percent_Identity=30.7984790874525, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=27.1317829457364, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=23.9700374531835, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=25.9541984732824, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788597, Length=266, Percent_Identity=25.187969924812, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790281, Length=202, Percent_Identity=24.2574257425743, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788682, Length=199, Percent_Identity=26.1306532663317, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=263, Percent_Identity=25.4752851711027, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=179, Percent_Identity=29.608938547486, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=177, Percent_Identity=29.9435028248588, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=271, Percent_Identity=22.5092250922509, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=175, Percent_Identity=24.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=204, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922422, Length=259, Percent_Identity=24.7104247104247, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI20129971, Length=305, Percent_Identity=22.6229508196721, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653477, Length=305, Percent_Identity=22.6229508196721, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654903, Length=226, Percent_Identity=23.8938053097345, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19920382, Length=178, Percent_Identity=32.5842696629214, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31594; Mature: 31594

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKLFGHKIICSSNKLSEKRSDMTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEIL
CEEEEECCEEEECCCHHHHHHHCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
EAIQLVKDNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVKIAELVQDISFAIK
HHHHHHCCCCCEEEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVG
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
LNRATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLV
CCCCEEEEEECCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
WQSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFQGK
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIVKLFGHKIICSSNKLSEKRSDMTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEIL
CEEEEECCEEEECCCHHHHHHHCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHH
EAIQLVKDNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVKIAELVQDISFAIK
HHHHHHCCCCCEEEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLPKPVILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVG
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
LNRATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLV
CCCCEEEEEECCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
WQSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFQGK
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA