BacMap

Definition	Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome.
Accession	NC_011134
Length	2,024,171

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The map label for this gene is dnaJ [H]

Identifier: 195977546

GI number: 195977546

Start: 432227

End: 433363

Strand: Direct

Name: dnaJ [H]

Synonym: Sez_0403

Alternate gene names: 195977546

Gene position: 432227-433363 (Clockwise)

Preceding gene: 195977545

Following gene: 195977547

Centisome position: 21.35

GC content: 46.97

Gene sequence:

>1137_bases
ATGAATAATACGGAATACTATGATCGTCTTGGGGTTTCAAAAGACGCTTCGGCCGATGATATTAAACGAGCTTACCGTAA
GATGTCTAAGAAATACCACCCAGACATCAATAAAGAGCCGGGAGCTGAGCAAAAATATAAGGACGTACAGGAAGCCTATG
AAACCCTAAGCGATTCACAAAAGCGTGCAGCCTATGATCAATACGGGGCAGCCGGAGCAAACGGTGGCTTTGGTGGTGGC
GCAGGCGGTTTTGGCGGCTTCGATGGTGGTGGCTTTGGCGGCTTTGAGGATATTTTCTCAAGCTTTTTTGGCGGTGGTGG
TATGCGTAATCCCAATGCTCCGCGTCAGGGTGATGACCTTCAATATAGGGTAAACCTTTCTTTTGAGGAAGCTGTTTTTG
GTACCGAAAAAGAGGTCAGTTATCATCGTGAATCAACCTGTAGCACCTGTGCAGGCTCAGGAGCTAAGCCTGGAACAAGT
CCTACAACCTGCCGTAAATGTCATGGCTCAGGGGTTATCAATGTTGATACGCAGACCCCACTTGGCATGATGCGTCGTCA
GGTGACCTGTGATATCTGTCATGGCAGCGGTCAGGAAATCAAAGAGCCTTGCCATACCTGTCATGGAACTGGTCATGAAA
AGAAGGTTCACAAGGTTTCAGTAAAAATCCCAGCAGGTGTTGAAACTGGCCAACAAATTCGCTTACAGGGTCAGGGTGAA
GCAGGCTTTAATGGTGGACCTTATGGTGATTTGTTCGTTATTTTAAACGTGCTTCCAAGTAAACAGTTTGAGCGCAATGG
CTCTACTATTTACTACAGCTTGAATATTTCATTTGTTCAGGCTGCTTTGGGAGATACAGTAGATATCCCAACGGTCCATG
GTGATGTTGCCATGTCTATTCCCGCTGGAACACAAACTGGTAAGGTATTTCGCTTGAAGGGCAAGGGGGCTCCTAAGCTT
CGAGGCGGAGGCCAAGGAGACCAGCATGTAACTGTAAACATTGTAACGCCTACCAAGCTCAATGAGGCTCAAAAGGAGGC
CTTGAAGGCTTTTGCGGAGGCTAGTGGCGAAAAGCCGATTGCTCCAAAGAAAAAAGGTTTCTTTGACAAGGTCAAAGACG
CTCTAGAGGATATTTAA

Upstream 100 bases:

>100_bases
CCCTAATTGCTAGAAAATAGCATAGCAAGGCTAAATAAATAAAAATCAAATAGGCGGGGCGCCTCGCTCCGTCTGTTTTT
GTCAATGAAGGAAAGAATAA

Downstream 100 bases:

>100_bases
GCGGGTCTTGTTTACACACTCTATGAGCGATTGATCACAATTGTATAGAAATGGTTGAGCATAGGTCATGCTAAAGCTGC
AGAGTCTGAGACATTTTTGT

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQKYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGG
AGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDICHGSGQEIKEPCHTCHGTGHEKKVHKVSVKIPAGVETGQQIRLQGQGE
AGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNISFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKL
RGGGQGDQHVTVNIVTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI

Sequences:

>Translated_378_residues
MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQKYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGG
AGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDICHGSGQEIKEPCHTCHGTGHEKKVHKVSVKIPAGVETGQQIRLQGQGE
AGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNISFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKL
RGGGQGDQHVTVNIVTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI
>Mature_378_residues
MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQKYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGG
AGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDICHGSGQEIKEPCHTCHGTGHEKKVHKVSVKIPAGVETGQQIRLQGQGE
AGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNISFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKL
RGGGQGDQHVTVNIVTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=373, Percent_Identity=34.5844504021448, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI205360840, Length=373, Percent_Identity=34.5844504021448, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI194328758, Length=303, Percent_Identity=32.013201320132, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI194328760, Length=303, Percent_Identity=32.013201320132, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI4504511, Length=295, Percent_Identity=32.5423728813559, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI5031741, Length=384, Percent_Identity=30.2083333333333, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI201862587, Length=362, Percent_Identity=31.767955801105, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI201862518, Length=362, Percent_Identity=31.767955801105, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI56549115, Length=362, Percent_Identity=31.767955801105, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7706495, Length=358, Percent_Identity=30.1675977653631, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI6631085, Length=360, Percent_Identity=30.5555555555556, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI5453690, Length=360, Percent_Identity=27.2222222222222, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI194328762, Length=259, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI47777312, Length=105, Percent_Identity=47.6190476190476, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI39204547, Length=369, Percent_Identity=23.3062330623306, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI23503241, Length=103, Percent_Identity=48.5436893203884, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI56687498, Length=68, Percent_Identity=55.8823529411765, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI9558755, Length=119, Percent_Identity=41.1764705882353, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI27151736, Length=107, Percent_Identity=45.7943925233645, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI88501736, Length=107, Percent_Identity=45.7943925233645, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI194306642, Length=104, Percent_Identity=43.2692307692308, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI194306640, Length=104, Percent_Identity=43.2692307692308, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI17388799, Length=105, Percent_Identity=51.4285714285714, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4885495, Length=111, Percent_Identity=50.4504504504504, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI21553335, Length=75, Percent_Identity=52, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI72534740, Length=107, Percent_Identity=41.1214953271028, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI68077168, Length=76, Percent_Identity=47.3684210526316, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI68077166, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI217035105, Length=76, Percent_Identity=43.421052631579, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22749377, Length=101, Percent_Identity=39.6039603960396, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI45504382, Length=67, Percent_Identity=47.7611940298507, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI29126218, Length=67, Percent_Identity=44.7761194029851, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786197, Length=383, Percent_Identity=46.7362924281984, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI1787235, Length=357, Percent_Identity=31.0924369747899, Blast_Score=168, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17553096, Length=368, Percent_Identity=36.6847826086957, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17553098, Length=368, Percent_Identity=36.6847826086957, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17507263, Length=348, Percent_Identity=32.183908045977, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17534355, Length=102, Percent_Identity=54.9019607843137, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538236, Length=112, Percent_Identity=44.6428571428571, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI212645553, Length=70, Percent_Identity=48.5714285714286, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115532378, Length=95, Percent_Identity=37.8947368421053, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554644, Length=112, Percent_Identity=37.5, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=371, Percent_Identity=34.5013477088949, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321094, Length=394, Percent_Identity=36.8020304568528, Blast_Score=159, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6323870, Length=355, Percent_Identity=33.5211267605634, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6323119, Length=368, Percent_Identity=28.5326086956522, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6324252, Length=423, Percent_Identity=25.531914893617, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322194, Length=105, Percent_Identity=45.7142857142857, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323813, Length=111, Percent_Identity=41.4414414414414, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320888, Length=105, Percent_Identity=39.0476190476191, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552811, Length=395, Percent_Identity=34.9367088607595, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI45552813, Length=389, Percent_Identity=36.5038560411311, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI45549272, Length=389, Percent_Identity=36.5038560411311, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI85726398, Length=363, Percent_Identity=32.5068870523416, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI20129487, Length=345, Percent_Identity=28.695652173913, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24584014, Length=345, Percent_Identity=28.695652173913, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646562, Length=393, Percent_Identity=29.7709923664122, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646560, Length=393, Percent_Identity=29.7709923664122, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646558, Length=393, Percent_Identity=29.7709923664122, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646556, Length=393, Percent_Identity=29.7709923664122, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21357547, Length=393, Percent_Identity=29.7709923664122, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19920464, Length=359, Percent_Identity=28.4122562674095, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28574949, Length=368, Percent_Identity=27.9891304347826, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24658562, Length=364, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24658555, Length=364, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI18858081, Length=358, Percent_Identity=26.2569832402235, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668492, Length=68, Percent_Identity=45.5882352941176, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654066, Length=118, Percent_Identity=35.5932203389831, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654070, Length=118, Percent_Identity=35.5932203389831, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654068, Length=118, Percent_Identity=35.5932203389831, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654072, Length=118, Percent_Identity=35.5932203389831, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737735, Length=67, Percent_Identity=49.2537313432836, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668523, Length=67, Percent_Identity=49.2537313432836, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574723, Length=67, Percent_Identity=49.2537313432836, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358273, Length=116, Percent_Identity=35.3448275862069, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 40384; Mature: 40384

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2 ; PS00637 DNAJ_CXXCXGXG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQKYKDVQEAYETLSDSQ
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCE
QYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTSPTTCRKCHGSGVINVDTQTP
EEEEECCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCC
LGMMRRQVTCDICHGSGQEIKEPCHTCHGTGHEKKVHKVSVKIPAGVETGQQIRLQGQGE
HHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEEEECCC
AGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNISFVQAALGDTVDIPTVHGDVAMSI
CCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCEEEEC
PAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNIVTPTKLNEAQKEALKAFAEASGEKPI
CCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
APKKKGFFDKVKDALEDI
CCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQKYKDVQEAYETLSDSQ
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCE
QYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTSPTTCRKCHGSGVINVDTQTP
EEEEECCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCC
LGMMRRQVTCDICHGSGQEIKEPCHTCHGTGHEKKVHKVSVKIPAGVETGQQIRLQGQGE
HHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEEEECCC
AGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNISFVQAALGDTVDIPTVHGDVAMSI
CCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCEEEEC
PAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNIVTPTKLNEAQKEALKAFAEASGEKPI
CCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
APKKKGFFDKVKDALEDI
CCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]