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The map label for this gene is hrcA [H]

Identifier: 195977543

GI number: 195977543

Start: 428181

End: 429215

Strand: Direct

Name: hrcA [H]

Synonym: Sez_0400

Alternate gene names: 195977543

Gene position: 428181-429215 (Clockwise)

Preceding gene: 195977542

Following gene: 195977544

Centisome position: 21.15

GC content: 42.9

Gene sequence:

>1035_bases
GTGATCACAGAGAGACAATCTAACATCTTGAATCTTATTGTAGATTTATTTACACAGACCCATGAACCGGTTGGCTCTAA
GGCTTTGCAGTCAGTTATTGCTTCTAGTAGTGCCACTATTAGAAATGACATGGCAAAGCTTGAAAAACTAGGATTGCTGG
AGAAGGCTCACACATCAAGTGGACGTATGCCAAGTGCGGCAGGCTTTAAATATTTTGTAGAGCATTCTCTTAACCTTGGC
AGCATTGATGAGCAGGATTTTTATCAGCTGGTCAAGGCCTTTGATTTTGAGGCCTTTAAGCTGGAGGACGTTTTGCTAAG
GGCTAGCCAGATGTTATCGGATATGACCGGCTATACGGCAGCGATTTTAGATGTCGAGCCTGCAAGGCAAAGACTGACAG
GCTTTGATATTGTTCAGCTATCTAGTCATGATGCCTTAGCTGTTTTGACCTTAGATGAGTCCAAGCCGTTGACCGTACAG
TTTGCCATTCCTAAGAATTTTATGAATCGTGATTTGCTGGTGCTTAAGGGCATTGTTGCTGATCGCTTACTTGGCAAAGA
TGTTATGACTGTTCATTACAAGCTGCGAACCGAAATCCCTCAGATTGTTCAGAAGTATTTTACGGTGACAGACAATGTTT
TGGATTTGTTTGATTATATCTTTGTCGGGCTTTTTCGAGAAACGATTTTTGTCTCTGGCAAGGTTGCTGCCCTTGACTAT
GCTGGTCTTGTGACCTATCAGTTTCTTGATGAGGAGCAGCGCTTAGCCCTATCTATCAGACAGAGTCTATCAGAGGAAGA
GATGGCAACGGTTCAGGTTGCTGACAGCAGTGAGCCAGCCCTAGCAAACGTGACCTTGCTGACCTACAAGTTTTTAATTC
CATACAGAGGATTTGGTCTTTTAAGCTTAATTGGGCCAGTTGATATGGATTATCGTCGTAGTGTTAGCTTGATTAATGTG
ATTGGTCAGCTGTTGGCCGTGAAGCTAAGAGATTATTACCGGTACTTAAACAGCAACCATTATGAGGTTCACTAA

Upstream 100 bases:

>100_bases
TTGAGTTTTTTTCTTGACATGCTAGTTTAAAAGGATATAATAGAACTATAAATTAGCAGTCCGATGTATAGAGTGCTAAC
AGAAAGGGAGTGATTGGTTT

Downstream 100 bases:

>100_bases
GGCCTTAATATGATTTAAGAAAATGTAAGAAAGGGGTAGACACCTTGTCTAAAAAACCAAAAGAAGAGCTCAAGGATCAA
GAGGACATTCTTGATGAGGC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDMAKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLG
SIDEQDFYQLVKAFDFEAFKLEDVLLRASQMLSDMTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQ
FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFDYIFVGLFRETIFVSGKVAALDY
AGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADSSEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINV
IGQLLAVKLRDYYRYLNSNHYEVH

Sequences:

>Translated_344_residues
MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDMAKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLG
SIDEQDFYQLVKAFDFEAFKLEDVLLRASQMLSDMTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQ
FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFDYIFVGLFRETIFVSGKVAALDY
AGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADSSEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINV
IGQLLAVKLRDYYRYLNSNHYEVH
>Mature_344_residues
MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDMAKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLG
SIDEQDFYQLVKAFDFEAFKLEDVLLRASQMLSDMTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQ
FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFDYIFVGLFRETIFVSGKVAALDY
AGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADSSEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINV
IGQLLAVKLRDYYRYLNSNHYEVH

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38757; Mature: 38757

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDMAKLEKLGLLEKAHTSS
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
GRMPSAAGFKYFVEHSLNLGSIDEQDFYQLVKAFDFEAFKLEDVLLRASQMLSDMTGYTA
CCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
AILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQFAIPKNFMNRDLLVLKGIVA
EEEECCHHHHHCCCCEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHH
DRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFDYIFVGLFRETIFVSGKVAALDY
HHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHH
AGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADSSEPALANVTLLTYKFLIPYRGFGL
HHHHHHHHHCHHHHHHHHHHHHCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHH
LSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYRYLNSNHYEVH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MITERQSNILNLIVDLFTQTHEPVGSKALQSVIASSSATIRNDMAKLEKLGLLEKAHTSS
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
GRMPSAAGFKYFVEHSLNLGSIDEQDFYQLVKAFDFEAFKLEDVLLRASQMLSDMTGYTA
CCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
AILDVEPARQRLTGFDIVQLSSHDALAVLTLDESKPLTVQFAIPKNFMNRDLLVLKGIVA
EEEECCHHHHHCCCCEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHH
DRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFDYIFVGLFRETIFVSGKVAALDY
HHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHH
AGLVTYQFLDEEQRLALSIRQSLSEEEMATVQVADSSEPALANVTLLTYKFLIPYRGFGL
HHHHHHHHHCHHHHHHHHHHHHCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHH
LSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYRYLNSNHYEVH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA