Click here to switch to the map view.

The map label for this gene is yicL [H]

Identifier: 195977535

GI number: 195977535

Start: 421317

End: 422261

Strand: Direct

Name: yicL [H]

Synonym: Sez_0392

Alternate gene names: 195977535

Gene position: 421317-422261 (Clockwise)

Preceding gene: 195977534

Following gene: 195977536

Centisome position: 20.81

GC content: 47.2

Gene sequence:

>945_bases
ATGTCAAGAAATGGAAAAGGCAGTACCATGATTTTACTAGCCGGAATCGCCTGGGGTCTCTCAGGGGTGTCAGGGCAATA
TTTAATTGCTCATGAGGTCGGCATCAATGCCTTGACCTCACTAAGGCTCATTATTTCAGGGCTTGTGCTATCAAGTATGG
CCTATATGCGACAGCGAGACGCTGTTATCCGACTGCTCAAGGACAAAAGGCTTTTAAGAGAGCTATTGATTTATAGCCTA
TTTGGCCTCACGCTGAATCAATATGCCTATTTGCTGGCTATTCGTTATTCTAACGCTGGTACAGCTACAGTCCTGCAATA
CCTTTCCCCCATTTTGGTGCTGGTCTATCTATCGTTCAAGTCAAGACGCCTGCCGGCTGCGGGAGAGAGCTGTGCTATTT
GCCTAGCGATCCTAGGAACGGTTATCATGGCCTGTCATGGGGACTTGTCGCATCTAGCGATTAATCCTATCGGGCTTTTC
TGGGGGCTTTTTGCAGCGGTGACCTATGCTTACTGTGTCATCAAGCCTGCTAAGCTGATTGCCGACTGGGGGAGCTTGCT
GATTGTTGGTCTTGCCATGCTGATGGGAGGAGTGATTTTTCCGATCCTGACAAGAGCATGGCAGTACCCATTGGCAATGA
CTTATGGGAATCTACGGGCCCTGTTTGGCATTATCGGTATTGGGACAATTTTTGCCTACACCTTTTTTCTAAAGGGGGCT
TCAATCATTGGGCCGATCAAGGCTACCTTGCTGGCTTCAATTGAGCCGGTTGCTTCAGTCTTTTTTGCGATTATCCTGAT
GAAAGAGACTTTTCACCCTATTGACCTGTTAGGGATGGCATTGATTTTAATAGCAGTGCTTGTGATATCGCTGAGAGACT
TACTGCTTGCTCAAAGAAAAAAGCAGCTAGCTCTTAAGGCCAAGCGACTACCATCATCTGACTGA

Upstream 100 bases:

>100_bases
TGTTAATGACTGTTAAGCAGGCTTGGTGAAGTCTAGGCTAGAGCTATCAAGGTATTATGAGTGGCCTTATCATGGCATGG
ATTAAAAAGAGGAAGATAAT

Downstream 100 bases:

>100_bases
TATAGAGCAAGGGTGTGCTATAATAAGACAAAACATAAAGGAGATTTGTGATGATTTGGTCATTAATTGTTGGTGCCATC
ATTGGTATGATTGCAGGCAG

Product: drug/metabolite transporter (DMT) superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHEVGINALTSLRLIISGLVLSSMAYMRQRDAVIRLLKDKRLLRELLIYSL
FGLTLNQYAYLLAIRYSNAGTATVLQYLSPILVLVYLSFKSRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLF
WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNLRALFGIIGIGTIFAYTFFLKGA
SIIGPIKATLLASIEPVASVFFAIILMKETFHPIDLLGMALILIAVLVISLRDLLLAQRKKQLALKAKRLPSSD

Sequences:

>Translated_314_residues
MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHEVGINALTSLRLIISGLVLSSMAYMRQRDAVIRLLKDKRLLRELLIYSL
FGLTLNQYAYLLAIRYSNAGTATVLQYLSPILVLVYLSFKSRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLF
WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNLRALFGIIGIGTIFAYTFFLKGA
SIIGPIKATLLASIEPVASVFFAIILMKETFHPIDLLGMALILIAVLVISLRDLLLAQRKKQLALKAKRLPSSD
>Mature_313_residues
SRNGKGSTMILLAGIAWGLSGVSGQYLIAHEVGINALTSLRLIISGLVLSSMAYMRQRDAVIRLLKDKRLLRELLIYSLF
GLTLNQYAYLLAIRYSNAGTATVLQYLSPILVLVYLSFKSRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLFW
GLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNLRALFGIIGIGTIFAYTFFLKGAS
IIGPIKATLLASIEPVASVFFAIILMKETFHPIDLLGMALILIAVLVISLRDLLLAQRKKQLALKAKRLPSSD

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI1790092, Length=312, Percent_Identity=34.9358974358974, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004779
- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 34093; Mature: 33962

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHEVGINALTSLRLIISGLVLSSMAYMRQRD
CCCCCCCCEEEEEHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIRLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTATVLQYLSPILVLVYLSFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
SRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLFWGLFAAVTYAYCVIKPAKLI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNLRALFGIIGIGTIFAYTFFLKGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SIIGPIKATLLASIEPVASVFFAIILMKETFHPIDLLGMALILIAVLVISLRDLLLAQRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQLALKAKRLPSSD
HHHHHHHHCCCCCC
>Mature Secondary Structure 
SRNGKGSTMILLAGIAWGLSGVSGQYLIAHEVGINALTSLRLIISGLVLSSMAYMRQRD
CCCCCCCEEEEEHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIRLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTATVLQYLSPILVLVYLSFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
SRRLPAAGESCAICLAILGTVIMACHGDLSHLAINPIGLFWGLFAAVTYAYCVIKPAKLI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNLRALFGIIGIGTIFAYTFFLKGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SIIGPIKATLLASIEPVASVFFAIILMKETFHPIDLLGMALILIAVLVISLRDLLLAQRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQLALKAKRLPSSD
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]