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The map label for this gene is yqhT [H]

Identifier: 195977495

GI number: 195977495

Start: 371684

End: 372781

Strand: Direct

Name: yqhT [H]

Synonym: Sez_0350

Alternate gene names: 195977495

Gene position: 371684-372781 (Clockwise)

Preceding gene: 195977494

Following gene: 195977496

Centisome position: 18.36

GC content: 45.26

Gene sequence:

>1098_bases
TTGTCGATAAAGGAGATTACCATGTCATCATTTTTAGCACAGCGCTTAAGCAATTGCCAAGCATTACTGGAAAAAAAGGG
CTTGGAGGCTATTTTAATTACTAATCTGACTAATATTTATTACCTGACAGGCTTTTCAGGGACCTCAGCTACGGTCTTTA
TCAGTCCAAAGCGGCGTGTTTTTATTACAGATTCGCGTTATACCTTGATTGCTAAGGCTAGTATTGAGGGCTTTGATATC
ATTGAGAGCCGCACACCGCTGGCTGAAATTGCTGCAATCCTACAGGCGGACAAGCTTAGCAGTCTAGCCTTTGAGGATCA
GGTGTCCTTTTCCTTTTATCAGCATCTCCAGGCTACTTTTGCTGGGGTGAGCTTGCTGCCGCAATCAGGCTTTATTGAAG
CGCTTCGTCTGATTAAGGACGCTTCTGAGATTGACATTATTGCTAAAGCCTGCTCGATTTCAGACAAGGCCTTCTGTGAT
GTCTTGGACTTTATTAAGCCGGGGCAGACAAGTGAGCTTGAGGTGGCTAATTTCTTGGATTTTCGCATGCGTCAATACGG
TGCCTCAGGCATTTCCTTTGACACCATTGCAGCCTCAGGCTATCGTTCTGCCATGCCTCATGGTCGTGCTACAGATAAAA
TCATTCAGCAGGGAGAGACTTTGACGCTTGACTTTGGCTGTTATTATCAGCATTATGTGAGTGATATGACAAGGACTATT
CATATCGGACAGGTGACAGACCAGGAGCGTGAGATTTATGAGCTGGTTCTTGCAGCTAATCAAGCCTTGATTGCAAAGGC
TAGTGCAGGCATGACCTATCGTGAGTTTGATGCTATTCCCCGTCAGCTGATTGCTGAGGCAGGATATGGCAGTCATTTCA
CACATGGTATTGGTCATGGGATCGGACTTGATATTCATGAGGATCCATTTTTTGCTAAGACAGACCAAAGGCTTCTTGCT
GGTATGGTGGTGACAGATGAGCCGGGTATCTATTTAGATGGCAAATACGGCGTGCGTATTGAGGACGATCTTGTCATCAC
AGAGACAGGCTGTCAGGTCTTAACCAAGGCACCAAAGGAATTGATTGTTTTAACGTAG

Upstream 100 bases:

>100_bases
ATTAGCCTTTTGATCCACTGTCAGAAATGCTTTTTTGTTGGCTTTCTCTAATGGGTCCTGCTTTTAAAAGCGTTGAAATC
ATGGTAAACTTAAGGTAGTT

Downstream 100 bases:

>100_bases
GCTTGTTAGCTGCTGTGAGCTAGGAGGAATTAGGAGACAAAAATGACAGATAGGCTATCATGGCAAGATTATTTTATGGC
AAATGCAGAGCTGATATCTA

Product: aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSIKEITMSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSATVFISPKRRVFITDSRYTLIAKASIEGFDI
IESRTPLAEIAAILQADKLSSLAFEDQVSFSFYQHLQATFAGVSLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCD
VLDFIKPGQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDFGCYYQHYVSDMTRTI
HIGQVTDQEREIYELVLAANQALIAKASAGMTYREFDAIPRQLIAEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLA
GMVVTDEPGIYLDGKYGVRIEDDLVITETGCQVLTKAPKELIVLT

Sequences:

>Translated_365_residues
MSIKEITMSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSATVFISPKRRVFITDSRYTLIAKASIEGFDI
IESRTPLAEIAAILQADKLSSLAFEDQVSFSFYQHLQATFAGVSLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCD
VLDFIKPGQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDFGCYYQHYVSDMTRTI
HIGQVTDQEREIYELVLAANQALIAKASAGMTYREFDAIPRQLIAEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLA
GMVVTDEPGIYLDGKYGVRIEDDLVITETGCQVLTKAPKELIVLT
>Mature_364_residues
SIKEITMSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSATVFISPKRRVFITDSRYTLIAKASIEGFDII
ESRTPLAEIAAILQADKLSSLAFEDQVSFSFYQHLQATFAGVSLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDV
LDFIKPGQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDFGCYYQHYVSDMTRTIH
IGQVTDQEREIYELVLAANQALIAKASAGMTYREFDAIPRQLIAEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAG
MVVTDEPGIYLDGKYGVRIEDDLVITETGCQVLTKAPKELIVLT

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=260, Percent_Identity=30.3846153846154, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI264681563, Length=226, Percent_Identity=30.0884955752212, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI93141226, Length=195, Percent_Identity=33.8461538461538, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI264681565, Length=223, Percent_Identity=28.6995515695067, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI149589008, Length=344, Percent_Identity=27.0348837209302, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI260593665, Length=315, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI260593663, Length=231, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788728, Length=360, Percent_Identity=39.1666666666667, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789275, Length=281, Percent_Identity=29.1814946619217, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17508215, Length=292, Percent_Identity=26.7123287671233, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=188, Percent_Identity=33.5106382978723, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71989583, Length=309, Percent_Identity=24.5954692556634, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321118, Length=296, Percent_Identity=26.3513513513513, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322999, Length=188, Percent_Identity=34.0425531914894, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320922, Length=268, Percent_Identity=27.2388059701493, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920384, Length=324, Percent_Identity=28.0864197530864, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357079, Length=288, Percent_Identity=28.4722222222222, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17137632, Length=240, Percent_Identity=28.3333333333333, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40222; Mature: 40091

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKEITMSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSATVFISPKRRV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCEEEEECCCCEE
FITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVSFSFYQHLQATF
EEECCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVSLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKPGQTSELEVANFLD
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
FRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDFGCYYQHYVSDMTRTI
HHHHHHCCCCCCCHHHCCCCHHHCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHEE
HIGQVTDQEREIYELVLAANQALIAKASAGMTYREFDAIPRQLIAEAGYGSHFTHGIGHG
EECCCCCHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCC
IGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIEDDLVITETGCQVLTKAPKE
CCCCCCCCCCCCCCCHHHHEEEEEECCCCEEECCCCCEEEECCEEEECCCHHHHHCCCCE
LIVLT
EEEEC
>Mature Secondary Structure 
SIKEITMSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSATVFISPKRRV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCEEEEECCCCEE
FITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVSFSFYQHLQATF
EEECCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVSLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKPGQTSELEVANFLD
HHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
FRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDFGCYYQHYVSDMTRTI
HHHHHHCCCCCCCHHHCCCCHHHCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHEE
HIGQVTDQEREIYELVLAANQALIAKASAGMTYREFDAIPRQLIAEAGYGSHFTHGIGHG
EECCCCCHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCC
IGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIEDDLVITETGCQVLTKAPKE
CCCCCCCCCCCCCCCHHHHEEEEEECCCCEEECCCCCEEEECCEEEECCCHHHHHCCCCE
LIVLT
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]