| Definition | Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome. |
|---|---|
| Accession | NC_011134 |
| Length | 2,024,171 |
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The map label for this gene is uvrA [H]
Identifier: 195977494
GI number: 195977494
Start: 368284
End: 371106
Strand: Direct
Name: uvrA [H]
Synonym: Sez_0349
Alternate gene names: 195977494
Gene position: 368284-371106 (Clockwise)
Preceding gene: 195977491
Following gene: 195977495
Centisome position: 18.19
GC content: 46.55
Gene sequence:
>2823_bases ATGCAAGATAAATTGATTATTCATGGGGCACGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCACGTGATAAGCT CGTTGTGGTGACAGGCTTATCAGGGTCTGGAAAATCTAGCCTTGCCTTTGATACCATTTATGCTGAGGGACAAAGGCGTT ATGTGGAGAGTTTGTCAGCCTATGCTAGGCAATTTTTAGGCAACATGGAAAAGCCTGATGTGGACTCTATAGACGGGCTT AGTCCTGCTATTTCTATTGACCAAAAAACAACCAGCAAGAATCCTAGATCAACCGTTGGTACGGTGACAGAAATCAATGA TTACCTCAGGCTTCTTTATGCGCGTGTGGGGACTCCCTATTGTATCAATGGGCATGGGGCTATTACGGCTTCTTCAGTGG AGCAGATTGTTGAGCAGGTGCTAGAGTTGCCTGAGCGGACGCGTATGCAGATTTTGGCGCCTCTTGTCCGTCGTAAAAAG GGACAGCACAAGACAGTGTTTGAGAAAATTCAAAAGGACGGTTATGTGCGCGTGCGTGTTGATGGAGAGATTTTTGATGT GTCAGAGGTACCAGCATTATCTAAAAGCAAAATGCACAATATAGAGGTCGTCATTGATCGCTTGGTCAATAAGGACGGGA TCCGCAGTCGTCTTTTTGATTCGATAGAGGCTGCGCTTCGCTTGGGAGATGGCTATCTGATGATTGATACGATGGACGGC AATGAGCTGCTGTTTTCAGAGTATTATTCCTGTCCGGTATGTGGTTTTACAGTGCCAGAGCTAGAGCCTCGTCTTTTTTC ATTTAACGCGCCCTTTGGCTCTTGCCCTACCTGTGATGGCTTAGGGATCAAGCTGGAGGTGGATTTAGATCTGGTTGTTC CTGATCCCAGCAAGACCTTGAGAGAGGGTGCCCTTGCTCCTTGGAATCCAATCTCGTCAAATTATTACCCAACCATGCTT GAGCAGGCAATGCAAAGCTTTGGCGTTGATATGGACAAGCCCTTTGAGCAATTGAGCGAGCAGGAAAAGGAGCTGATCTT GTATGGCTCAGGTGATCAAGAGTTCCATTTTCACTATGTCAATGATTTTGGTGGCGAGCGCAGCATTGATATTCCCTTTG AAGGGGTTGTGACAAATATCAACCGTCGCTACCATGAGACTAGCAGTGATTACACCCGCAATGTCATGCGAGGGTACATG AATGAATTGACCTGTGCTGCCTGTCATGGCTATCGTCTCAACGATCAAGCCTTGTGTGTGCGTGTTGGTGGTGAGCATGG CTTGACTATTGGTCAGGTATCAGAGCTATCTATTGCAGACCACTTGCAGCTGCTGGATGGGCTTGAGCTATCAGACAATG AAAGCACCATTGCAAAGCCAATTATCAAGGAAATTCATGATCGGCTGACCTTTTTGAATAATGTCGGTCTGAATTATCTG ACCTTGTCTCGCTCGGCAGGTACCTTGTCTGGTGGAGAGAGTCAGCGTATCCGTTTGGCAACGCAAATTGGCTCTAATCT GTCAGGCGTCCTTTATGTTTTGGACGAGCCTTCTATTGGTCTGCACCAGCGAGATAACGATCGCTTGATTGATAGCTTGA AAAAAATGCGTGACTTGGGAAACACCTTGATTGTGGTTGAGCACGATGAGGATACCATGATGCAGGCAGATTGGCTGATT GATGTGGGACCTAGTGCTGGGGACTTTGGCGGGCAGATTGTTGCCTCTGGAACGCCTCAGCAGGTTGCTCGGCATAAAAG GTCTATCACTGGTCAATACCTGTCTGGACGCAAATCAATACCCGTTCCTTTGGAGCGACGTGCTGGCAATGGCCGATTTA TTGATATCAAGGGAGCAGCCCAAAACAATCTGCAAAATCTTGATGTAAGGTTTCCTCTAGGGAAATTTATTGCAGTGACT GGGGTCTCTGGCTCAGGAAAATCAACGCTGGTTAACAGCATTCTCAAAAAAGCAGTGGCTCAAAAGCTAAACCGTAACTC TGAAAAGCCAGGCAGGCATAGGTCTATCACTGGCATTGAACATTTGGAGCGTCTGATTGATATTGATCAAAGCCCAATTG GGCGGACACCGCGCTCTAATCCTGCCACCTATACTGGTGTTTTTGATGATATTCGAGAGCTTTTTGCCCAGACTAATGAA GCCAAGATTCGTGGCTACAAAAAAGGGCGCTTCTCCTTTAATGTAAAAGGTGGGCGCTGTGAGGCCTGCTCTGGAGATGG GATTATCAAGATTGAGATGCATTTTTTGCCAGATGTCTACGTTCCATGTGATGTTTGTCATGGCAGACGCTATAATTCAG AGACGTTGGAGGTCCATTATAAGGGCAAAAATATTGCTGAAATCTTGGATATGACGGTAGATGATGCTCTGGTATTTTTC TCAGCGATTCCAAAGATTGCTCGTAAAATTCAGACGATTAAGGACGTTGGGCTTGGCTATGTTACTCTAGGGCAGCCAGC AACAACCCTATCAGGTGGTGAGGCCCAGCGCATGAAGCTGGCGAGTGAGCTGCACAAGCGCTCAACTGGTAAAAGCTTGT ATATTTTAGATGAGCCAACGACGGGGCTGCATACAGATGACATTGCACGATTGCTGAAGGTTTTAGAGCGTTTTGTTGAT GATGGCAATACGGTTTTAGTGATTGAGCACAATTTAGATGTCATCAAGTCGGCAGACCATATTATTGACCTTGGTCCAGA AGGCGGTGTTGGTGGAGGTCAATTGGTTGCAGCTGGGACTCCTGAAGAGGTTGCCGCTGTTGAGGAAAGCTACACAGGGC AGTACCTGAAGCTGAAATTGTAG
Upstream 100 bases:
>100_bases TTATACTACAAATTCATAGTGTTTGGGGCAACTGATTATTAGAAATTTTTGTTATAATGGAATAAATCTCGATGAGGAGG GTGCCTAAGGGCACAAGAGC
Downstream 100 bases:
>100_bases GGCTGTGGGCCTGACATCTATCGACAGAGTGAGTTTCGTATTATTGGTGTGGGAGTGCAGATTGAGATGCCAGTTGGTGA GGTTTACCTCTGGGTGGGCA
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 940; Mature: 940
Protein sequence:
>940_residues MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRLFDSIEAALRLGDGYLMIDTMDG NELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTML EQAMQSFGVDMDKPFEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETSSDYTRNVMRGYM NELTCAACHGYRLNDQALCVRVGGEHGLTIGQVSELSIADHLQLLDGLELSDNESTIAKPIIKEIHDRLTFLNNVGLNYL TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLI DVGPSAGDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRFIDIKGAAQNNLQNLDVRFPLGKFIAVT GVSGSGKSTLVNSILKKAVAQKLNRNSEKPGRHRSITGIEHLERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNE AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALVFF SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQLVAAGTPEEVAAVEESYTGQYLKLKL
Sequences:
>Translated_940_residues MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRLFDSIEAALRLGDGYLMIDTMDG NELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTML EQAMQSFGVDMDKPFEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETSSDYTRNVMRGYM NELTCAACHGYRLNDQALCVRVGGEHGLTIGQVSELSIADHLQLLDGLELSDNESTIAKPIIKEIHDRLTFLNNVGLNYL TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLI DVGPSAGDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRFIDIKGAAQNNLQNLDVRFPLGKFIAVT GVSGSGKSTLVNSILKKAVAQKLNRNSEKPGRHRSITGIEHLERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNE AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALVFF SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQLVAAGTPEEVAAVEESYTGQYLKLKL >Mature_940_residues MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRLFDSIEAALRLGDGYLMIDTMDG NELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTML EQAMQSFGVDMDKPFEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETSSDYTRNVMRGYM NELTCAACHGYRLNDQALCVRVGGEHGLTIGQVSELSIADHLQLLDGLELSDNESTIAKPIIKEIHDRLTFLNNVGLNYL TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLI DVGPSAGDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRFIDIKGAAQNNLQNLDVRFPLGKFIAVT GVSGSGKSTLVNSILKKAVAQKLNRNSEKPGRHRSITGIEHLERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNE AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALVFF SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQLVAAGTPEEVAAVEESYTGQYLKLKL
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=56.2765957446808, Blast_Score=1054, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 103756; Mature: 103756
Theoretical pI: Translated: 6.18; Mature: 6.18
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSA CCCCEEEECCCCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH YARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPY HHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCE CINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKKGQHKTVFEKIQKDGYVRVRV EECCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEE DGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRLFDSIEAALRLGDGYLMIDTMDG CCCEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEEECCC NELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKTL CEEHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEEEECCCHHHH REGALAPWNPISSNYYPTMLEQAMQSFGVDMDKPFEQLSEQEKELILYGSGDQEFHFHYV HCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCEEEEEEE NDFGGERSIDIPFEGVVTNINRRYHETSSDYTRNVMRGYMNELTCAACHGYRLNDQALCV CCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEE RVGGEHGLTIGQVSELSIADHLQLLDGLELSDNESTIAKPIIKEIHDRLTFLNNVGLNYL EECCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLG EEECCCCCCCCCCCCEEEEEEHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC NTLIVVEHDEDTMMQADWLIDVGPSAGDFGGQIVASGTPQQVARHKRSITGQYLSGRKSI CEEEEEECCCCCEEEECEEEEECCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHCCCCCC PVPLERRAGNGRFIDIKGAAQNNLQNLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVA CCCHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHH QKLNRNSEKPGRHRSITGIEHLERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNE HHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCC AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHY HHEEEEECCEEEEEECCCEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEE KGKNIAEILDMTVDDALVFFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKL CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH ASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADH HHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCC IIDLGPEGGVGGGQLVAAGTPEEVAAVEESYTGQYLKLKL EEEECCCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEC >Mature Secondary Structure MQDKLIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSA CCCCEEEECCCCCCCCCCEEECCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH YARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPY HHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCE CINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKKGQHKTVFEKIQKDGYVRVRV EECCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEE DGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRLFDSIEAALRLGDGYLMIDTMDG CCCEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEEECCC NELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKTL CEEHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEEEECCCHHHH REGALAPWNPISSNYYPTMLEQAMQSFGVDMDKPFEQLSEQEKELILYGSGDQEFHFHYV HCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCEEEEEEE NDFGGERSIDIPFEGVVTNINRRYHETSSDYTRNVMRGYMNELTCAACHGYRLNDQALCV CCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEE RVGGEHGLTIGQVSELSIADHLQLLDGLELSDNESTIAKPIIKEIHDRLTFLNNVGLNYL EECCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLG EEECCCCCCCCCCCCEEEEEEHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC NTLIVVEHDEDTMMQADWLIDVGPSAGDFGGQIVASGTPQQVARHKRSITGQYLSGRKSI CEEEEEECCCCCEEEECEEEEECCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHCCCCCC PVPLERRAGNGRFIDIKGAAQNNLQNLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVA CCCHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHH QKLNRNSEKPGRHRSITGIEHLERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNE HHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCC AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHY HHEEEEECCEEEEEECCCEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEE KGKNIAEILDMTVDDALVFFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKL CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHH ASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADH HHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCC IIDLGPEGGVGGGQLVAAGTPEEVAAVEESYTGQYLKLKL EEEECCCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11296296 [H]