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The map label for this gene is pgi [H]

Identifier: 195977350

GI number: 195977350

Start: 223758

End: 225107

Strand: Direct

Name: pgi [H]

Synonym: Sez_0203

Alternate gene names: 195977350

Gene position: 223758-225107 (Clockwise)

Preceding gene: 195977349

Following gene: 195977351

Centisome position: 11.05

GC content: 44.67

Gene sequence:

>1350_bases
ATGTCACATATTACATTTGATTATTCAAAGGTTCTTGAGCAATTTGCCGGACAGCATGAAATTGACTTTTTACAAGGTCA
GGTAACAGAGGCTGACCAGGCACTACGTCAGGGCACTGGACCTGGATCAGATTTCTTGGGCTGGCTTGAGTTACCTGAAA
ACTATGACAAAGAAGAATTTGCTCGTATCCTTAAAGCAGCTGAGAAGATTAAGGCTGACAGTGACGTTCTTGTTGTGATT
GGTATTGGTGGCTCTTACCTTGGTGCTAAGGCTGCGATTGACTTTTTAAACAGCCATTTTGCCAACCTACAAACAGCAAA
AGAGCGCAAAGCACCCCAAATTCTTTATGCTGGTAACTCCATCTCATCAAGCTATCTTGCTGATCTTGTGGACTATGTTC
AAGATAAGGATTTCTCTGTTAACGTGATTTCTAAGTCTGGTACAACAACAGAGCCTGCAATCGCCTTTCGTGTCTTTAAA
GAATTACTTGTTAAAAAGTACGGTCAAGAAGAGGCCAACAAGCGTATCTATGCAACGACTGATAAGGTCAAGGGTGCTGT
TAAGGTTGAGGCTGATGCAAATCATTGGGAAACCTTTGTTGTGCCAGATAATGTTGGTGGCCGTTTCTCAGTGCTGACAG
CTGTGGGCTTGCTACCAATTGCAGCATCAGGGGCTGATATTACCGCGCTGATGGAAGGAGCAAATGCAGCTCGTAAGGAC
CTGTCATCAGATAAAATCTCAGAAAACATCGCTTACCAATATGCTGTGGTCCGCAATATCCTCTACCGCAAAGGCTATGT
GACTGAAATTTTGGCAAACTACGAGCCATCATTGCAGTATTTTAGCGAATGGTGGAAGCAGCTGGCTGGTGAGTCTGAAG
GCAAGGACCAAAAGGGTATCTACCCAACTTCAGCTAATTTCTCGACAGACCTGCATTCTCTTGGTCAATTTATCCAAGAA
GGCTACCGTAACCTCTTTGAGACAGTGATTCGTGTGGACAAGCCACGTCAAAATGTGATTATCCCAGAAATGGCTGAGGA
CCTTGATGGCCTTGGCTACCTACAAGGAAAAGACGTTGACTTTGTCAACAAAAAAGCAACAGATGGTGTCCTTCTTGCCC
ATACAGATGGTGGTGTGCCAAATATGTTTATCACGCTTCCAGAGCAAGACGAATTTACACTAGGCTATACGATCTACTTC
TTTGAGCTTGCTATTGCCCTTTCAGGCTACCTCAACGGGGTCAATCCATTTGATCAGCCAGGCGTTGAGGCTTACAAGAA
AAACATGTTTGCCCTTCTTGGTAAGCCAGGCTTTGAAGAGCTAGGAGCAGCGCTCAACGCACGCTTGTAA

Upstream 100 bases:

>100_bases
CTAGGAGTAGCCACCTGTTTCTTAAATATAAAAACATTGAAATATTGAATAGAAAAGGTTATGATACTAATGAAACTTTA
AAAGTTAAGGGAGTAAAATA

Downstream 100 bases:

>100_bases
TGACAGAGCTAGCTAGACTAGTCTGCTAAAACATAACAAAGAGTCTCGTGAAAGGCTCTTTTTTTTGCTTCTTTTCAAGG
TCGGTTAGGCTTATCAAGGC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSDFLGWLELPENYDKEEFARILKAAEKIKADSDVLVVI
GIGGSYLGAKAAIDFLNSHFANLQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
LSSDKISENIAYQYAVVRNILYRKGYVTEILANYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE
GYRNLFETVIRVDKPRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEFTLGYTIYF
FELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL

Sequences:

>Translated_449_residues
MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSDFLGWLELPENYDKEEFARILKAAEKIKADSDVLVVI
GIGGSYLGAKAAIDFLNSHFANLQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
LSSDKISENIAYQYAVVRNILYRKGYVTEILANYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE
GYRNLFETVIRVDKPRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEFTLGYTIYF
FELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL
>Mature_448_residues
SHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSDFLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIG
IGGSYLGAKAAIDFLNSHFANLQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFKE
LLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDL
SSDKISENIAYQYAVVRNILYRKGYVTEILANYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEG
YRNLFETVIRVDKPRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEFTLGYTIYFF
ELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Escherichia coli, GI1790457, Length=389, Percent_Identity=25.4498714652956, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319673, Length=375, Percent_Identity=24.8, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 49509; Mature: 49378

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSDFLGWLELPENYDKEEF
CCCEECCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHH
ARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFANLQTAKERKAPQILYAGNS
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
ISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEH
DKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
HHHCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHC
LSSDKISENIAYQYAVVRNILYRKGYVTEILANYEPSLQYFSEWWKQLAGESEGKDQKGI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
YPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDKPRQNVIIPEMAEDLDGLGYLQGKDVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCCCCCCCC
FVNKKATDGVLLAHTDGGVPNMFITLPEQDEFTLGYTIYFFELAIALSGYLNGVNPFDQP
CCCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCC
GVEAYKKNMFALLGKPGFEELGAALNARL
CHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSDFLGWLELPENYDKEEF
CCEECCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHH
ARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFANLQTAKERKAPQILYAGNS
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
ISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEH
DKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
HHHCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHC
LSSDKISENIAYQYAVVRNILYRKGYVTEILANYEPSLQYFSEWWKQLAGESEGKDQKGI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
YPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDKPRQNVIIPEMAEDLDGLGYLQGKDVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCCCCCCCC
FVNKKATDGVLLAHTDGGVPNMFITLPEQDEFTLGYTIYFFELAIALSGYLNGVNPFDQP
CCCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCC
GVEAYKKNMFALLGKPGFEELGAALNARL
CHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA