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The map label for this gene is pbpZ [H]

Identifier: 195977258

GI number: 195977258

Start: 111990

End: 114290

Strand: Direct

Name: pbpZ [H]

Synonym: Sez_0107

Alternate gene names: 195977258

Gene position: 111990-114290 (Clockwise)

Preceding gene: 195977256

Following gene: 195977259

Centisome position: 5.53

GC content: 44.94

Gene sequence:

>2301_bases
ATGGTGAAATGGAAAAAGAATCAAACAAGCAAAAATCATCAGCGATTGGAATTAGTTGATTTTGGAACGGTCTTTTTGCG
CACATTAAAATTCATGTCGAGCTTTTTTTATGTAGCTGTCTTTTTATTTGGCATGCTGGGTGCTGGTATGGCCTTTGGCT
ATTTAGCCAGTCAAATTGACTCGGTAAAAATTCCAAGCAAGGAAAGCCTTGTCAAGCAGGTTGAATCATTGACCATGATG
TCACAGATCACTTATTCAGACAATAGCTTGATTTCAGGCATTGATACGGATCTGCTTAGGACACCGGTTGCTAGTGATGC
GATTTCAGATAATATTAAAAAGGCCATTGTCTCAACTGAGGACGACAACTTTCAGCGTCATAAGGGCGTTGTACCAAAGG
CGGTTTTTCGTGCGACTCTGGCCTCTGTTTTGGGCTTTGGGGAGTCAAGTGGTGGCTCTACGCTGACACAGCAATTGATT
AAGCAGCAGGTTTTGGGCGATGATCCGACCTTTAGGCGAAAATCAAAGGAAATTATCTATGCACTGGCCCTAGAGCGTTA
CATGTCAAAGGACGATATTTTATCACATTATTTGAACGTGTCGCCTTTTGGTCGTAATAATAAGGGGCAAAACATTGCAG
GTGTGGAGGAGGCTGCGCGTGGGATTTTTGGAGTCTCTGCAAAGGATCTGACGGTTCCGCAGGCGGCCTTTTTGGCAGGG
CTTCCGCAAAGCCCGATTGTTTATTCGCCGTATTTGCCGACAGGGCAGTTAAAATCAGCCGAGGATATGGCCTATGGGAT
TAAGCGCCAGCAAAATGTCCTCTATAACATGTATCGAACAGGTGTGCTGACAGAAAAAGAATATCGTGATTATAAGGCAT
ACCCTATTAGCAATGATTTTATCAAACCTGAAACAGTCACTGCCAATACTCATGATTACCTCTACTATTCTGTCTTGGCA
GAGGCACAAAAGGCTATGTATAGCTATCTGATCAAGCGAGATAAGGTTCCTGCTAAAGATTTAAAAAATGATGAGACTAA
GGCTGCCTATGAGGAGCGGGCCTTAACGGAGCTACAGCATGGTGGCTACACTGTCAAAACAACAATCAATAAATCAATCC
ATCAGGTGATGCAAAAAGCGGCAGCTCAGTTTGGTGGCTTGTTAGACGATGGCACTGGGACAGTGCAGATGGGCAATGTC
CTAACAGACAATGCTACAGGAGCTGTTTTGGGCTTTATTGGTGGCAGAGACTATGCTCAAAATCAAAACAATCATGCCTT
TAATACTGTTCGCTCTCCAGGCTCTAGCATTAAGCCGATTATTGCTTATGGACCTGCCATTGATCAGGGATTAATGGGAA
GTGCTAGTGTCCTATCCAACTATCCGACGACCTATTCCAGCGGTCAAAAAATCATGCACGTCGATAGTGAAGGAACAGCA
ATGATGCCCTTGCAGGAGGCGCTTAATACCTCATGGAATATTCCAGCCTTTTGGACTCAAAAGCTGCTGCGTGATAAGGG
CGTTGATGTTGAAAACTATATGAGTAAAATGGGGTATCGGATTGCTGATTATTCCATTGAAAGTCTGCCACTTGGTGGTG
GGATTGAGACCTCGGTAGCCCAGCAGACCAATGCTTATCAGATGATTGCTAATAATGGTCTTTATCAAAAGCAATATATG
GTGGCTAGTATCACAGCTAGTGATGGATCCGTTGTTTATCAGCATGAGGCTAAGCCAGTTCGTATTTTTTCAGCTCCAAC
AGCCACAATTTTGCAGGAGCTCTTGAGAGGGCCGATTTCATCTGGGGCAACAACCACTTTTAAAAGCCGATTAGCAGGGA
TCAACCCAAGCCTTGCAGGTGCTGACTGGATAGGTAAAACAGGAACAACCGAAAATTATACCGATGTCTGGCTGGTCTTA
GCTACTCCAAGGGTTACTTTGGGTGGTTGGGCAGGCCATGATGACAATACCTCGCTTGCACCACTGACGGGATACAATAA
TAATTCAAATTACATGGCTTATTTGGTTAATGCCATCAGTCAGGCTGATCCAAATATTTTTGGCCTTGGTCAGCGGTTTT
CACTGGATCCTGGTGTTATCAAGGCTTCTGTCTTGAAGGCCACTGGTCTAAAGCCGGGTACAGTGACGATCAATGGCCAA
ACCATCTCCGTCGGTGGAGAGCTAACAACCAGCCTCTGGGCTCAAAAGGGACCCGGAGCAACTACCTATAGGTTTGCCAT
TGGGGGGACAGATGCAGACTATCAAAAAGCCTGGGGAGGCTTTAGTGGTAGAAGAAATTAG

Upstream 100 bases:

>100_bases
TTTCTCCATTTTCTTTATGATTTCCGAATCATTATATCAAAAATGACTGTGGCTGTGCAAGCTTAATCAAAGTTTGGTAT
AATGAAGATTGAGGTACGTT

Downstream 100 bases:

>100_bases
TTGTATTTTCCAGACAAATAGTGTATAATATCCGTAACTATTTGTCGTCTAATCTAGCTGAAATATTGTCCAGCTAGAAA
GAACAGCAGTTAAATCACAC

Product: multimodular transpeptidase-transglycosylase

Products: NA

Alternate protein names: PBP-1F; Penicillin-binding protein F [H]

Number of amino acids: Translated: 766; Mature: 766

Protein sequence:

>766_residues
MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFGMLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMM
SQITYSDNSLISGIDTDLLRTPVASDAISDNIKKAIVSTEDDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLI
KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAG
LPQSPIVYSPYLPTGQLKSAEDMAYGIKRQQNVLYNMYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLA
EAQKAMYSYLIKRDKVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKSIHQVMQKAAAQFGGLLDDGTGTVQMGNV
LTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQGLMGSASVLSNYPTTYSSGQKIMHVDSEGTA
MMPLQEALNTSWNIPAFWTQKLLRDKGVDVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYM
VASITASDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWIGKTGTTENYTDVWLVL
ATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQADPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQ
TISVGGELTTSLWAQKGPGATTYRFAIGGTDADYQKAWGGFSGRRN

Sequences:

>Translated_766_residues
MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFGMLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMM
SQITYSDNSLISGIDTDLLRTPVASDAISDNIKKAIVSTEDDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLI
KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAG
LPQSPIVYSPYLPTGQLKSAEDMAYGIKRQQNVLYNMYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLA
EAQKAMYSYLIKRDKVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKSIHQVMQKAAAQFGGLLDDGTGTVQMGNV
LTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQGLMGSASVLSNYPTTYSSGQKIMHVDSEGTA
MMPLQEALNTSWNIPAFWTQKLLRDKGVDVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYM
VASITASDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWIGKTGTTENYTDVWLVL
ATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQADPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQ
TISVGGELTTSLWAQKGPGATTYRFAIGGTDADYQKAWGGFSGRRN
>Mature_766_residues
MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFGMLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMM
SQITYSDNSLISGIDTDLLRTPVASDAISDNIKKAIVSTEDDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLI
KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAG
LPQSPIVYSPYLPTGQLKSAEDMAYGIKRQQNVLYNMYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLA
EAQKAMYSYLIKRDKVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKSIHQVMQKAAAQFGGLLDDGTGTVQMGNV
LTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQGLMGSASVLSNYPTTYSSGQKIMHVDSEGTA
MMPLQEALNTSWNIPAFWTQKLLRDKGVDVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYM
VASITASDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWIGKTGTTENYTDVWLVL
ATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQADPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQ
TISVGGELTTSLWAQKGPGATTYRFAIGGTDADYQKAWGGFSGRRN

Specific function: Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI87082258, Length=355, Percent_Identity=29.2957746478873, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1788867, Length=581, Percent_Identity=25.9896729776248, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786343, Length=599, Percent_Identity=24.3739565943239, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789601, Length=179, Percent_Identity=31.2849162011173, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.-; 3.4.-.- [C]

Molecular weight: Translated: 83393; Mature: 83393

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFGMLGAGMAFGYLASQID
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTPVASDAISDNIKKAIVSTE
CCCCCCHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHCCC
DDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLIKQQVLGDDPTFRRKSKEIIY
CCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAG
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHC
LPQSPIVYSPYLPTGQLKSAEDMAYGIKRQQNVLYNMYRTGVLTEKEYRDYKAYPISNDF
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCC
IKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRDKVPAKDLKNDETKAAYEERALTELQH
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHC
GGYTVKTTINKSIHQVMQKAAAQFGGLLDDGTGTVQMGNVLTDNATGAVLGFIGGRDYAQ
CCEEEEEHHHHHHHHHHHHHHHHHCCEEECCCCCEEECCEEECCCCCEEEEECCCCCHHC
NQNNHAFNTVRSPGSSIKPIIAYGPAIDQGLMGSASVLSNYPTTYSSGQKIMHVDSEGTA
CCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCE
MMPLQEALNTSWNIPAFWTQKLLRDKGVDVENYMSKMGYRIADYSIESLPLGGGIETSVA
ECCHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCHHHH
QQTNAYQMIANNGLYQKQYMVASITASDGSVVYQHEAKPVRIFSAPTATILQELLRGPIS
HHCCCHHHHHCCCCCEEEEEEEEEEECCCCEEEEECCCCEEEECCCHHHHHHHHHCCCCC
SGATTTFKSRLAGINPSLAGADWIGKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLA
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCC
PLTGYNNNSNYMAYLVNAISQADPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQ
EEECCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCE
TISVGGELTTSLWAQKGPGATTYRFAIGGTDADYQKAWGGFSGRRN
EEEECCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFGMLGAGMAFGYLASQID
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTPVASDAISDNIKKAIVSTE
CCCCCCHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHCCC
DDNFQRHKGVVPKAVFRATLASVLGFGESSGGSTLTQQLIKQQVLGDDPTFRRKSKEIIY
CCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEAARGIFGVSAKDLTVPQAAFLAG
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHC
LPQSPIVYSPYLPTGQLKSAEDMAYGIKRQQNVLYNMYRTGVLTEKEYRDYKAYPISNDF
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCC
IKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRDKVPAKDLKNDETKAAYEERALTELQH
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHC
GGYTVKTTINKSIHQVMQKAAAQFGGLLDDGTGTVQMGNVLTDNATGAVLGFIGGRDYAQ
CCEEEEEHHHHHHHHHHHHHHHHHCCEEECCCCCEEECCEEECCCCCEEEEECCCCCHHC
NQNNHAFNTVRSPGSSIKPIIAYGPAIDQGLMGSASVLSNYPTTYSSGQKIMHVDSEGTA
CCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCE
MMPLQEALNTSWNIPAFWTQKLLRDKGVDVENYMSKMGYRIADYSIESLPLGGGIETSVA
ECCHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCHHHH
QQTNAYQMIANNGLYQKQYMVASITASDGSVVYQHEAKPVRIFSAPTATILQELLRGPIS
HHCCCHHHHHCCCCCEEEEEEEEEEECCCCEEEEECCCCEEEECCCHHHHHHHHHCCCCC
SGATTTFKSRLAGINPSLAGADWIGKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLA
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCC
PLTGYNNNSNYMAYLVNAISQADPNIFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQ
EEECCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCE
TISVGGELTTSLWAQKGPGATTYRFAIGGTDADYQKAWGGFSGRRN
EEEECCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8335642; 1459957 [H]