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The map label for this gene is znuB [H]

Identifier: 195977256

GI number: 195977256

Start: 109614

End: 110447

Strand: Direct

Name: znuB [H]

Synonym: Sez_0105

Alternate gene names: 195977256

Gene position: 109614-110447 (Clockwise)

Preceding gene: 195977255

Following gene: 195977258

Centisome position: 5.42

GC content: 41.13

Gene sequence:

>834_bases
ATGAGAGCAAAGGAGGGTCATTCCATGCTTGAGATTTTATCTTATGATTTTATGCAGCGTGCTGTTATGGCTGTTGTGGC
GATCAGTATCTTTGCTCCGATTTTGGGTATCTTTTTGATTTTGCGTCGTCAAAGCTTGTTGAGTGATACGCTTAGCCACG
TTTCTCTGGCTGGTGTGGCCTTTGGTGTTGTTCTTGGTGTTTCGCCAACCTTCACAACGATTATTGTGGTGGTGCTAGCT
GCCATCTTGCTAGAATATCTTAGGGTGGTTTATAAGCACTATATGGAGATTTCGACAGCTATCCTAATGTCCTTGGGGCT
GGCTATTTCCTTGATTATCATGAGTAAGTCAACTAGCTCTTCTAGTATGAGCTTGGAGCAATACCTTTTTGGCTCTATCA
TTACTATTAGTACGGAGCAGGTTGCTGCCTTATTTATCATCGCTTTGATTATTTTAGCCTTGACGATATTATTTATTCGT
CCAATGTATATCTTGACCTTCGATGAGGACACAGCCTATGTCGATGGCTTGCCAGTGCGTGTCATGTCTGTTTTGTTTAA
TATTGTGACAGGTGTTGCTATTGCTCTGACGATCCCAGCGGCAGGAGCCCTTTTGGTATCAACGATTATGGTTTTGCCAG
CAAGTATTGCCATGCGGCTTGGTAAGAATTTTAAATCGGTTATTTTTCTTGGGATTATGATTGGCTTTACAGGTATGCTG
TCTGGTATTTTCTTGTCCTATTTTTGGGAAACGCCAGCAAGTGCGACCATTACGATGATTTTTATTATTATCTTTCTTAT
GGTTAACCTCTTGTCCTTTATTCGCAAAACATAA

Upstream 100 bases:

>100_bases
GACCCAGAGGAGGTCAAGGCTTATGCTGATCGAAATATTCATTTGATTAGAAATCAACGGCTTCCTTGGCGCTGCTTCAA
CATTCATGATGCTGAGGCTG

Downstream 100 bases:

>100_bases
TCATCAAAAAGCAAGATTTTCCTAGCTGTCAGATAAACACCTCTGTTTGCTCTGCCTTTTCTAGAATAGCTACTTGGAGA
AAGGCTCTAATCAATACTAA

Product: Zinc ABC transporter inner membrane permease protein ZnuB

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRAKEGHSMLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLSHVSLAGVAFGVVLGVSPTFTTIIVVVLA
AILLEYLRVVYKHYMEISTAILMSLGLAISLIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFIIALIILALTILFIR
PMYILTFDEDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKSVIFLGIMIGFTGML
SGIFLSYFWETPASATITMIFIIIFLMVNLLSFIRKT

Sequences:

>Translated_277_residues
MRAKEGHSMLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLSHVSLAGVAFGVVLGVSPTFTTIIVVVLA
AILLEYLRVVYKHYMEISTAILMSLGLAISLIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFIIALIILALTILFIR
PMYILTFDEDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKSVIFLGIMIGFTGML
SGIFLSYFWETPASATITMIFIIIFLMVNLLSFIRKT
>Mature_277_residues
MRAKEGHSMLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLSHVSLAGVAFGVVLGVSPTFTTIIVVVLA
AILLEYLRVVYKHYMEISTAILMSLGLAISLIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFIIALIILALTILFIR
PMYILTFDEDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKSVIFLGIMIGFTGML
SGIFLSYFWETPASATITMIFIIIFLMVNLLSFIRKT

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=242, Percent_Identity=28.099173553719, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 30185; Mature: 30185

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAKEGHSMLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLSHVSLAGVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAISLIIMSKSTSS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SSMSLEQYLFGSIITISTEQVAALFIIALIILALTILFIRPMYILTFDEDTAYVDGLPVR
HHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCHHCCCHHH
VMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKSVIFLGIMIGFTGML
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SGIFLSYFWETPASATITMIFIIIFLMVNLLSFIRKT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAKEGHSMLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLSHVSLAGVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAISLIIMSKSTSS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SSMSLEQYLFGSIITISTEQVAALFIIALIILALTILFIRPMYILTFDEDTAYVDGLPVR
HHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCHHCCCHHH
VMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKSVIFLGIMIGFTGML
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SGIFLSYFWETPASATITMIFIIIFLMVNLLSFIRKT
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]